Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10354 products of "Benzimidazole and Imidazole Derivatives"
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Scopolamine-d3 Hydrobromide Hydrate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),<br></p>Formula:C17H18D3NO4·BrH·xH2OColor and Shape:NeatMolecular weight:387.284-(1H-1,2,4-Triazol-1-ylmethyl)benzonitrile
CAS:Controlled ProductFormula:C10H8N4Color and Shape:WhiteMolecular weight:184.20(R)-Pregabalin
CAS:Controlled Product<p>Impurity Pregabalin USP Related Compound A<br>Applications R-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia (less potent than the S-Enantiomer). Pregabalin USP Related Compound A.<br>References Field, M.J. et al.: Br. J. Pharmacol., 132, 1 (2001); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993);<br></p>Formula:C8H17NO2Color and Shape:WhiteMolecular weight:159.23Methyl Methanesulfonate
CAS:<p>Applications Methyl Methanesulfonate is used as a reagent in the synthesis of 2-Methyllamotrigine (M315350); an impurity of Lamotrigine (L173250) which is an anticonvulsant that inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Also used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986); Grunze, et al.: Neuropsychobiology, 38, 131 (1998); Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999)<br></p>Formula:C2H6O3SColor and Shape:Colourless LiquidMolecular weight:110.134-Methyl Mebendazole
CAS:Controlled Product<p>Applications Mebendazole (M200500) related compound as anthelmintic agent.<br>References Raeymaekers, A.H.M., et al.: Arzneim.-Forsch., 28, 586 (1978),<br></p>Formula:C17H15N3O3Color and Shape:NeatMolecular weight:309.32Voriconazole-d3
CAS:Controlled Product<p>Applications Labelled Vorizonazole (V760000), used as an antifungal (systemic). An Ergosterol Biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C162H3H11F3N5OColor and Shape:White To BeigeMolecular weight:352.33Modafinil-d5 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Labelled Modafinil (M482502). Modafinil is an α-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease.This is a controlled substance (stimulant).<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999)<br></p>Formula:C152H5H10NO2SColor and Shape:NeatMolecular weight:278.38Iminostilbene
CAS:Controlled Product<p>Impurity Carbamazepine EP Impurity D<br>Applications A metabolite of Carbamazepine (CBZ) (C175840).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001),<br></p>Formula:C14H11NColor and Shape:Yellow To Dark OrangeMolecular weight:193.24Omeprazole Sulfone N-Oxide
CAS:<p>Impurity Omeprazole EP Impurity I<br>Applications Omeprazole Sulfone N-Oxide (Omeprazole EP Impurity I) is a metabolite of Omeprazole. Impurity I.<br>References Stevens, C.M., et al.: J. Biol. Chem., 75, 182 (1950), Okamoto, S., et al.: Biochem. Biophys. Res. Commun., 101, 440 (1981)<br></p>Formula:C17H19N3O5SColor and Shape:NeatMolecular weight:377.418(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one (Mixture of Regioisomers)
CAS:Controlled Product<p>Impurity Omeprazole EP Impurity F+Omeprazole EP Impurity G<br>Stability Sample unstable under MS condition<br>Applications 8(9)-Methoxy-1,3-dimethyl-12-thioxopyrido[1’,2’:3,4]imidazo[1,2-a]benzimidazol-2-(12H)-one(Mixture of Regioisomers) (Omeprazole EP Impurity F+Omeprazole EP Impurity G) is a mixture of regioisomers of Omeprazole Impurity.<br>References Rackur, G., et al.: Biochem. Biophys. Res. Commmun., 128, 477 (1985),<br></p>Formula:C16H13N3O2SColor and Shape:NeatMolecular weight:311.362-((1,3-DIOXOISOINDOLIN-2-YL)METHYL)OXAZOLE-4-CARBOXYLIC ACID
CAS:Purity:95.0%Molecular weight:272.21600341796875Rivastigmine N-Oxide (Technical Grade)
CAS:Controlled Product<p>Applications Rivastigmine N-Oxide is an impurity of Rivastigmine (R541000, Tartrate Salt) which is a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Brit. Med. J., 318, 633 (1999), Enz, A., et al.: Prog. Brain Res., 98, 431 (1993)<br></p>Formula:C14H22N2O3Color and Shape:Light Yellow LiquidMolecular weight:266.34para-Clotrimazole Isomer
CAS:Controlled Product<p>Impurity Clotrimazole EP Impurity B<br>Applications para-Clotrimazole Isomer (Clotrimazole EP Impurity B) is a positional isomer of the antifungal agent (C587400). It showed agonistic activity on the pregnane X receptor and regulated the levels of apoA1 and HDL-cholesterol in rodents.<br>References Buechel, K.H. et al.: Drugs Made Ger., 15, 79 (1972); Bachmann, K. et al.: Pharmacol. Res., 50, 237 (2004);<br></p>Formula:C22H17ClN2Color and Shape:NeatMolecular weight:344.845-Desamino 5-Oxo-2,5-dihydro Lamotrigine
CAS:Controlled Product<p>Impurity Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C<br>Applications 5-Desamino 5-Oxo-2,5-dihydro Lamotrigine (Lamotrigine EP Impurity A; Lamotrigine USP Related Compound C) is an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Formula:C9H6Cl2N4OColor and Shape:White SolidMolecular weight:257.082-Chlorotrityl Chloride (90%)
CAS:Controlled Product<p>Impurity Clotrimazole EP Impurity C<br>Applications 2-Chlorotrityl Chloride (Clotrimazole EP Impurity C) is used in convergent peptide synthesis. 2-Chlorotrityl Chloride is also used in the preparation of modified trityl nucleosides as inhibitors of P. falciparum dUTPase.<br>References Ruda, G.F. et al.: ChemMedChem, 6, 309 (2011); Athanassopoulos, P. et al.: Tetrahed. Lett., 36, 5645 (1995);<br></p>Formula:C19H14Cl2Purity:90%Color and Shape:NeatMolecular weight:313.22Rufinamide
CAS:<p>Applications Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant. Neuroprotective & Neuroresearch Product.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H8F2N4OColor and Shape:White To Off-WhiteMolecular weight:238.194-Methoxy-2-nitroaniline(2-Nitro-p-anisidine)
CAS:Controlled Product<p>Applications Toxic to some wild and domestic birds and mice. Molluscicidal activity<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References De Abreu, F. et al.; Bioorg. Med. Chem. 9, 659 (2001); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 14, 111 (1985); Schafer, E.W. et al.; Arch. Environ. Con. Tox. 12, 355 (1983)<br></p>Formula:C7H8N2O3Color and Shape:NeatMolecular weight:168.152,4-Dihydro-4-[4-[4-(4-hydroxyphenyl]-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
CAS:Controlled Product<p>Applications An intermediate in the synthesis of Itraconazole.<br></p>Formula:C22H27N5O2Color and Shape:NeatMolecular weight:393.48Atropine Sulfate Monohydrate
CAS:Controlled Product<p>Applications Mydriatic; antispasmodic; used in preanesthetic medication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, R.V., et al.: Br. J. Pharmacol., 15, 170 (1960), Shutt, L.E., et al.: Anaesthesia, 34, 476 (1979), Hinderling, P.H., et al.: J. Pharm. Sci., 74, 703 (1985),<br></p>Formula:C17H23NO3·H2O·H2O4SColor and Shape:White To Light YellowMolecular weight:694.83
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