
Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10354 products of "Benzimidazole and Imidazole Derivatives"
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6-O-Desmethyl Donepezil-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Donepezil (D531750), an inhibitor of acetylcholinesterase.<br>References De Vos, F., et al.: Nuc. Med. Biol., 27, 745 (2000), Okereke, C., et al.: Brit. J. Clin. Pharmacol., 58, 41 (2004),<br></p>Formula:C232H5H22NO3Color and Shape:NeatMolecular weight:370.50tert-Butyl 2-bromo-1-methyl-1H-imidazole-4-carboxylate
CAS:Purity:97%Molecular weight:261.11898803710945-(1-Biphenyl-4-yl-1H-tetrazol-5-yl)-4-methyl-pyrimidin-2-ylamine
CAS:Color and Shape:SolidMolecular weight:329.36700439453125Isometronidazole
CAS:Controlled Product<p>Impurity Metronidazole EP Impurity E<br>Applications Isometronidazole (Metronidazole EP Impurity E) is an impurity of Metronidazole (M338880), a chemotherapeutic agent that is used as a first line defense against Clostridium difficile (C.diff). Isometronidazole is also a hypoxic cell sensitizer in humans and mice.<br>References Hentschel, M. & Schmidt, W.: Die Pharm., 47, 221 (1992); Musher, D., et al.: Clin. Inf. Dis., 40, 1586 (2005); Rosenkranz, H. & Speck, W.: Biochem. Biophys. Res. Comm., 66, 520 (1975)<br></p>Formula:C6H9N3O3Color and Shape:NeatMolecular weight:171.155,6-DIMETHYL-2-(PYRIDIN-3-YL)-1H-BENZO[D]IMIDAZOLE
CAS:Purity:95.0%Molecular weight:223.2790069580078(S)-Luliconazole
CAS:Controlled Product<p>Applications (S)-Luliconazole is the (S)--enantiomer of Luliconazole, an azole antifungal drug. Luliconazole was found to interfere with ergosterol biosynthesis in cell-free extracts of Candida albican, while no interference due to (S)-Luliconazole was found.<br>References Uhida, K., et al.: J. Infect. Chemother., 10, 216 (2004); Niwano, ., et al.: Antimicro. Agents Chemother., 42, 967 (1998); Niwanno, Y., et al.: Med. Mycol., 37, 351 (1999)<br></p>Formula:C14H9Cl2N3S2Color and Shape:NeatMolecular weight:354.28Hydroxy Voriconazole
Controlled Product<p>Applications A hydroxylated derivative of Voriconazole (V760000), a systemic antifungal and ergosterol biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997).<br></p>Formula:C16H14F3N5O2Color and Shape:NeatMolecular weight:365.31(1R)-(-)-10-Camphorsulfonic Acid
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity E (1R)-Isomer<br>Stability Hygroscopic<br>Applications (1R)-(-)-10-Camphorsulfonic Acid (Voriconazole EP Impurity E (1R)-Isomer) is a chiral derivative of Camphor. Used in the preparation of a chiral recognition polymer that is used in the chiral separation of amino acids. A catalyst in direct animation of α-branched aldehydes (including important biological molecules such as α-Me phenylglycine) with near perfect enantioselectivity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guo, H. et al.: Polym. Preprints Am. Chem. Soc., 40, 506 (1999); Liu, C. et al.: Org. Lett., 13, 2638 (2011);<br></p>Formula:C10H16O4SColor and Shape:WhiteMolecular weight:232.303-(1 H -Benzoimidazol-2-yl)-4-chloro-phenylamine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:243.690002441406253,5-Didesamino-3,5-dioxo Lamotrigine
CAS:Controlled Product<p>Impurity Lamotrigine EP Impurity D<br>Applications 3,5-Didesamino-3,5-dioxo Lamotrigine (Lamotrigine EP Impurity D) is an impurity of the anticonvulsant Lamotrigine (L173250).<br>References Hlavac, J. et al.: ARKIVOC, 1, 22 (2003);<br></p>Formula:C9H5Cl2N3O2Color and Shape:NeatMolecular weight:258.06Hydroxy Metronidazole
CAS:<p>Applications A metabolite of Metronidazole (M338880).<br>References Haller, I., et al.: Antimicrob. Agents Chemother., 22, 165 (1982), Gibson, R., et al.: Clin. Chem., 30, 784 (1984), Kuti, J., et al.: Pharmacotherapy, 25, 935 (2005),<br></p>Formula:C6H9N3O4Color and Shape:WhiteMolecular weight:187.15Iminodibenzyl 5-Carbonyl Chloride
CAS:Controlled ProductFormula:C15H12ClNOColor and Shape:NeatMolecular weight:257.71Efinaconazole
CAS:Controlled Product<p>Applications Efinaconazole is a topical antifungal for onychomycosis. (Synonyms: KP-103)<br>References Sugiura, K., et. al.: Antimicrob. Agents CH., 58, 3837 (2014);<br></p>Formula:C18H22F2N4OColor and Shape:NeatMolecular weight:348.39Benznidazole
CAS:<p>Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.<br>References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),<br></p>Formula:C12H12N4O3Color and Shape:NeatMolecular weight:260.254-Chloro-6-nitro-1,3-dihydro-2H-benzo[d]imidazol-2-one
CAS:Purity:98%Molecular weight:213.5800018310547

