Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10354 products of "Benzimidazole and Imidazole Derivatives"
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Rupatadine-d4 Fumarate
CAS:Controlled Product<p>Applications Labelled Rupatadine (R701650). Rupatadine is a dual antagonist of histamine H1 and platelet-activating factor receptors. Rupatadine is used as an antihistaminic.<br>References Merlos, M., et al.: J. Pharmacol. Exp. Ther., 280, 114 (1997), Guadano, E.M., et al.: Allergy, 59, 766 (2004),<br></p>Formula:C30H26D4ClN3O4Color and Shape:NeatMolecular weight:536.053-(2,3-Dichlorobenzamido) Lamotrigine
CAS:<p>Impurity Lamotrigine EP Impurity F/ Lamotrigine Related Compound D<br>Stability Light Sensitive<br>Applications 3-(2,3-Dichlorobenzamido) Lamotrigine (Lamotrigine EP Impurity F) an impurity of the anticonvulsant Lamotrigine (L173250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Emami, J. et al.: J. Pharmac. Biomed. Anal., 40, 999 (2006); Srinivasulu, P. et al.: Chromatographia, 70, 271 (2009);<br></p>Formula:C16H9Cl4N5OColor and Shape:NeatMolecular weight:429.094-Nitro-1H-imidazole
CAS:Controlled Product<p>Applications Metronidazole (M338880) derivative, an antibacterial in the treatment of rosacea and inflammatory bowel disease.<br>References Khan, K. et al.; Am. J. Gastroenterol. 106, 661 (2011)<br></p>Formula:C3H3N3O2Color and Shape:NeatMolecular weight:113.074-(2-Methylpropyl)piperidine-2,6-dione
CAS:Formula:C9H15NO2Color and Shape:White SolidMolecular weight:169.2210,11-Dihydro-10-hydroxy Carbamazepine-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Oxcarbazepine (O869250).<br>References Burkhart, C., et al.: Clin. Exp. Allergy, 32, 1635 (2002), Pearce, R., et al.: Drug Metab. Dispos., 30, 1170 (2002), Naisbitt, D., et al.: Mol. Pharmacol., 63, 732 (2003), Farrell, J., et al.: Br. J. Clin. Pharmacol., 57, 690 (2004),<br></p>Formula:C152H3H11N2O2Color and Shape:Off WhiteMolecular weight:257.305-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications 5-Hydroxy Omeprazole is the main metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O4SColor and Shape:NeatMolecular weight:361.42N-(3-(1H-imidazol-1-yl)propyl)-6-ethoxybenzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:302.3999938964844(S)-Lansoprazole
CAS:Controlled Product<p>Applications The S-enantiomer of Lansoprazole; a gastric proton pump inhibitor. An antiulcerative.<br>References Figgitt, D., et al.: Drugs, 60, 925 (2000), Katsuki, H., et al.: Eur. J. Clin. Pharmacol., 57, 709 (2001), Barradell, L.B., et al.: Drugs, 44, 225 (1992), Kim, K., et al.: Clin. Pharmacol. Ther., 72, 90 (2002), Niioka, T., et al.: Ther. Drug Monit., 28, 321 (2006),<br></p>Formula:C16H14F3N3O2SColor and Shape:NeatMolecular weight:369.36Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone
CAS:Controlled Product<p>Applications Bis[(1S)-3,4-dihydro-1-phenyl-2(1H)-isoquinolinyl]-methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence.<br>References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006)<br></p>Formula:C31H28N2OColor and Shape:NeatMolecular weight:444.575-(4-chlorophenyl)-1-(2-methoxyphenyl)-2,3-dihydro-1H-imidazole-2-thione
Molecular weight:316.79998779296875Albendazole Sulfoxide
CAS:<p>Impurity Albendazole EP Impurity B<br>Applications Albendazole Sulfoxide (Albendazole EP Impurity B) is a metabolite of Albendazole, an anthelmintic.<br>References Dominguez, L., et al.: Farmaco, 50, 697 (1995), De Laurentis, N., et al.: Pharm. Pharmacol Lett., 6, 2: 51 (1996)<br></p>Formula:C12H15N3O3SColor and Shape:White To BrownMolecular weight:281.335-Bromo-1-(3,4-dimethoxyphenyl)-1H-benzo[d]imidazole
CAS:Purity:98%Molecular weight:333.184997558593755-(4-chlorophenyl)-1-[2-(propan-2-yl)phenyl]-2,3-dihydro-1H-imidazole-2-thione
CAS:Purity:97%Molecular weight:328.85998535156252-{[(1-butyl-1H-benzimidazol-2-yl)amino]methyl}phenol
CAS:Purity:95.0%Molecular weight:295.3859863281252,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Controlled Product<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Formula:C13H14F3N3OColor and Shape:NeatMolecular weight:285.26
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