Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester (>90%)
<p>Impurity Fesoterodine Impurity 6;<br>Applications 1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester is derived from (R)-Fesoterodine Fumarate (F321300), which is a muscarinic receptor antagonist for the treatment of Lower Urininary Tract Symptoms (LUTS). It is very similar to Tolterodine (T535800).<br>References Rogers, D., et al.: Pharmacotherapy, 20, 1092 (2000), Praharaj, S., et al.: J. Psychopharmacology, 19, 426 (2005),<br></p>Formula:C26H35NO5Purity:>90%Color and Shape:NeatMolecular weight:441.56Ternidazole-d6 Hydrochloride (>90%)
CAS:Controlled Product<p>Applications Labelled Ternidazole (T116500). An antiparasitic nitroimidazole.<br>References Tramontano, E., et al.: Biochem. Pharmacol., 43, 1371 (1992), Schafer, W., et al.: J. Med. Chem., 36, 726 (1993),<br></p>Formula:C7H6D6ClN3O3Purity:>90%Color and Shape:NeatMolecular weight:227.68Modafinil-d5 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Labelled Modafinil (M482502). Modafinil is an α-1-adrenergic agonist. Modafinil is a CNS stimulant; psychostimulant that displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease.This is a controlled substance (stimulant).<br>References Saletu, B., et al.: Int. J. Clin. Pharmacol. Res., 9, 183 (1989), Chemelli, R.M., et al.: Cell, 98, 437 (1999)<br></p>Formula:C152H5H10NO2SColor and Shape:NeatMolecular weight:278.384-Methyl Mebendazole
CAS:Controlled Product<p>Applications Mebendazole (M200500) related compound as anthelmintic agent.<br>References Raeymaekers, A.H.M., et al.: Arzneim.-Forsch., 28, 586 (1978),<br></p>Formula:C17H15N3O3Color and Shape:NeatMolecular weight:309.325-Bromo-1-(3,4-dimethoxyphenyl)-1H-benzo[d]imidazole
CAS:Purity:98%Molecular weight:333.184997558593753-(1 H -Benzoimidazol-2-yl)-4-chloro-phenylamine
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:243.69000244140625Methyl Methanesulfonate
CAS:<p>Applications Methyl Methanesulfonate is used as a reagent in the synthesis of 2-Methyllamotrigine (M315350); an impurity of Lamotrigine (L173250) which is an anticonvulsant that inhibits glutamate release, possible through inhibition of sodium, potassium and calcium currents. Also used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986); Grunze, et al.: Neuropsychobiology, 38, 131 (1998); Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999)<br></p>Formula:C2H6O3SColor and Shape:Colourless LiquidMolecular weight:110.13(R)-Pregabalin
CAS:Controlled Product<p>Impurity Pregabalin USP Related Compound A<br>Applications R-Enantiomer of Pregabalin. A GABA analogue used as an anticonvulsant. Anxiolytic analgesic used to treat peripheral neuropathic pain and fibromyalgia (less potent than the S-Enantiomer). Pregabalin USP Related Compound A.<br>References Field, M.J. et al.: Br. J. Pharmacol., 132, 1 (2001); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993);<br></p>Formula:C8H17NO2Color and Shape:WhiteMolecular weight:159.23Rupatadine-d4 Fumarate
CAS:Controlled Product<p>Applications Labelled Rupatadine (R701650). Rupatadine is a dual antagonist of histamine H1 and platelet-activating factor receptors. Rupatadine is used as an antihistaminic.<br>References Merlos, M., et al.: J. Pharmacol. Exp. Ther., 280, 114 (1997), Guadano, E.M., et al.: Allergy, 59, 766 (2004),<br></p>Formula:C30H26D4ClN3O4Color and Shape:NeatMolecular weight:536.05Itraconazole Mono N-Oxide
Controlled ProductFormula:C35H38Cl2N8O5Color and Shape:NeatMolecular weight:721.63Imidacloprid
CAS:Controlled Product<p>Applications A neonicotinoid; the active ingredient in certain neuro-active insecticides. Reports show that when exposed to neonicotinid pesticides honeybees have problems returning home after foraging and bumblebee colonies grow poorly and produce fewer queens. Imidacloprid is useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009), Tomizawa, M., et al.: J. Med. Chem., 52, 3735 (2009), Chem. and Eng. News 90: 10 (2012)<br></p>Formula:C9H10ClN5O2Color and Shape:NeatMolecular weight:255.66Scopolamine-13C, D3 Hydrobromide
CAS:Controlled Product<p>Applications Scopolamine-13C, d3 Hydrobromide, is the labeled analogue of Scopolamine-d3 Hydrobromide (S200002), an acetylcholine antagonist, used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brand, J.J., et al.: Lancet, 2, 232 (1970), Bowles, J.B., et al.: Anaesthesia, 34, 476 (1979), Clissold, S.P., et al.: Drugs, 29, 189 (1985), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 19, 477 (1990),<br></p>Formula:C1613CH19D3BrNO4Color and Shape:Off-WhiteMolecular weight:388.285-Hydroxy Omeprazole Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications The main metabolite of Omeprazole.<br>References Renberg, L., et al.: Drug Metab. Dispos., 17, 69 (1989), Calabresi, L., et al.: Pharmacol. Res., 49, 493 (2004), Yin, O., et al.: J. Clin. Pharmacol., 44, 582 (2004),<br></p>Formula:C17H18N3NaO4SColor and Shape:White To Light YellowMolecular weight:383.40Omeprazole Sulfide Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Omeprazole Sulfide Hydrochloride is a metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H19N3O2S·HClColor and Shape:NeatMolecular weight:329.42 + 36.46cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolane-4-methanol
CAS:Controlled ProductFormula:C13H13Cl2N3O3Color and Shape:NeatMolecular weight:330.17Secnidazole
CAS:Controlled Product<p>Applications Analog of Metronidazole. Antiamebic. Antiprotozoal (Trichomonas).<br>References Cosar, C., et al.: Arzneim.-Forsch., 16, 23 (1966), Videau, D., et al.: Br. J. Vener. Dis., 54, 77 (1978), Symonds, J., et al.: J. Antimicrob. Chemother., 5, 484 (1979),<br></p>Formula:C7H11N3O3Color and Shape:White To Light YellowMolecular weight:185.182'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-carbaldehyde
CAS:Purity:98%Molecular weight:250.261001586914061'-Hydroxy Triazolam
CAS:Controlled Product<p>Applications A metabolite of Triazolam (T767380(M)), which is a sedative; a controlled substance (depressant).<br>References Boxenbaum, H., et al.: J. Pharm. Pharm. Sci., 2, 47 (1999), Perloff, M., et al.: J. Pharmacol. Exp. Ther., 292, 618 (2000), Patki, K., et al.: Drug Metab. Dispos., 31, 938 (2003),<br></p>Formula:C17H12Cl2N4OColor and Shape:Light GreenMolecular weight:359.21
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