Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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N-Nitroso Albendazole (mixtures of regional isomers)
Controlled ProductFormula:C13H16N4O3SColor and Shape:NeatMolecular weight:616.7123-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane Bromide
CAS:Controlled Product<p>Applications 3-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane is an impurity in the synthesis of Clidinium Bromide (C576250), an anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formula:C8H16BrNOColor and Shape:NeatMolecular weight:222.12Oxybutynin-d10 Hydrochloride
CAS:Controlled Product<p>Applications Oxybutynin-d10 Hydrochloride is a labeled analogue of Oxybutynin Chloride (O868525), an inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells.<br>References Park, J.M., et al.: J. Urol., 162, 1110 (1999); Watson, M., et al.: Brit. J. Pharmacol., 127, 590 (1999)<br></p>Formula:C22H22D10ClNO3Color and Shape:NeatMolecular weight:404.01(S)-Aclidinium Bromide
CAS:Controlled Product<p>Applications (S)-Aclidinium Bromide is an isomer of Aclidinium Bromide (A190180) a novel long-acting antimuscarinic bronchodilator in phase II clinical trials for the treatment of chronic obstructive pulmonary disease (1,2).<br>References (1) Gupta, V. and Singh, D.: Expert Rev Respir Med. 6, 581 (2012)(2) De La Motte, S., et al.: Int. J. Clin. Pharmacol. Therap., 50,403 (2012)<br></p>Formula:C26H30BrNO4S2Color and Shape:Off-WhiteMolecular weight:564.55N-Nitrosoiminodibenzyl
CAS:Controlled ProductFormula:C14H12N2OColor and Shape:NeatMolecular weight:224.26Omeprazole Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Omeprazole Sodium Salt is the salt analogue of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C17H18N3O3S·Na·H2OColor and Shape:Off-WhiteMolecular weight:385.41Butyl Itraconazole
CAS:Controlled ProductFormula:C35H38Cl2N8O4Color and Shape:NeatMolecular weight:705.635,6-Dimethoxyindane-1,3-dione
CAS:Controlled ProductFormula:C11H10O4Color and Shape:NeatMolecular weight:206.19(2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
CAS:Controlled ProductFormula:C13H15F2N3O4SColor and Shape:NeatMolecular weight:347.342-Aminobenzimidazole
CAS:Controlled ProductFormula:C7H7N3Color and Shape:BeigeMolecular weight:133.15Prazepam
CAS:Controlled Product<p>Applications Prazepam, is a benzodiazepine derivative drug having anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.<br>References Shader R. I., et al.: Ciba. Found. Symp., (74), 141 (1979); Jacqmin, P., et al.: Neuropsychobiology, 19 (4), 186 (1988);<br></p>Formula:C19H17ClN2OColor and Shape:Off-WhiteMolecular weight:324.80Scopolamine Sulfate
CAS:Controlled Product<p>Applications Scopolamine Sulfate is an impurity of Scopolamine (S200000), an acetylcholine antagonist used in the treatment of motion sickness and also used as antiemetic, antispasmodic, mydriatic, preanesthetic agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Trendelenburg P., et al.: Archiv fuer Exper. Pathol. Pharmacol., 73, 118 (1914);<br></p>Formula:C17H21NO7SColor and Shape:NeatMolecular weight:383.422-Deschlorothien-3-yl Tioconazole Hydrochloride
CAS:Controlled Product<p>Applications 2-Deschloro Tioconazole Hydrochloride is an analog of Tioconazole (T444680), an antifungal that is more active than Fluconazole (F421000) or Voriconazole (V760000) against Candida glabrata mutant strains. Antifungal (topical).<br>References Jevons, S., et al.: Antimicrob. Agents Chemother., 15, 597 (1979), Clayton, Y.M., et al.: Clin. Exp. Dermatol., 7, 543 (1982), Marriott, M.S., et al.: Dermatologica, 166, 1 (1983),<br></p>Formula:C16H14Cl2N2OS·ClHColor and Shape:NeatMolecular weight:389.73ent-Voriconazole
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity D; Voriconazole USP Related Compound B<br>Applications ent-Voriconazole (Voriconazole USP Related Compound B; Voriconazole EP Impurity D) is the (2S,3R) enantiomer in Voriconazole (V760000) drug substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gage, R., et al.: J. Pharm. Biomed. Anal., 17, 1449 (1998), Owens, P., et al.: Enantiomer, 4, 79 (1999), Pehourcq, F., et al.: Biomed. Chromatogr., 18, 719 (2004), Sellers, J., et al.: J. Pharm. Biomed. Anal., 41, 1088 (2006),<br></p>Formula:C16H14F3N5OColor and Shape:NeatMolecular weight:349.311-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid (>75%)
CAS:<p>Impurity Rabeprazole EP Impurity C<br>Applications 1-(1H-Benzo[d]imidazol-2-yl)-3-methyl-4-oxo-1,4-dihydropyridine-2-carboxylic acid (>75%) (Rabeprazole EP Impurity C) is a Rabeprazole (R070500) impurity. A degradation product formed in stressed tablets of Rabeprazole sodium.<br>References Kommanaboyina, B., et al.: Drug Dev. Ind. Pharm., 25, 857 (1999), Carswel, C., et al.: Drugs, 61, 2327 (2001), Garcia, C., et al.: J. Pharm. Biomed. Anal., 46, 88 (2008),<br></p>Formula:C14H11N3O3Purity:>75%Color and Shape:NeatMolecular weight:269.262-[2-(2-Methyl-4-nitroimidazol-1-yl)ethoxy]ethanol
CAS:Controlled ProductFormula:C8H13N3O4Color and Shape:NeatMolecular weight:215.21Tiotropium-d6 Bromide
CAS:Controlled ProductFormula:C19H16D6BrNO4S2Color and Shape:White To PurpleMolecular weight:478.45Midazolam-d6 (1 mg/mL in Acetonitrile)
CAS:Controlled ProductFormula:C18D6H7ClFN3Color and Shape:Single SolutionMolecular weight:331.80
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