Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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Triazolam
CAS:Controlled Product<p>Applications Sedative, hypnotic.Controlled substance (depressant).<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981)<br></p>Formula:C17H12Cl2N4Color and Shape:WhiteMolecular weight:343.21Triclabendazole Sulfoxide-D3
CAS:Controlled Product<p>Applications Triclabendazole Sulfoxide-D3 is a stable isotopically labelled metabolite of Triclabendazole (T774175), an anthelmintic.<br>References Wolff, K., et al.: Vet. Parasitol., 13, 145 (1983)<br></p>Formula:C14H6D3Cl3N2O2SColor and Shape:NeatMolecular weight:378.682,3,4,5-Tetrahydro-3-(trifluoroacetyl)-1,5-methano-1H-3-benzazepine-7,8-diamine
CAS:Controlled Product<p>Applications Varenicline intermediate.<br>References Coe, J., et al.: J. Med. Chem., 48, 3474 (2005),<br></p>Formula:C13H14F3N3OColor and Shape:NeatMolecular weight:285.26N-methyl-1-(1-phenyl-1H-tetrazol-5-yl)cyclohexanamine
CAS:Purity:95.0%Molecular weight:257.34100341796875Tinidazole-d5
CAS:Controlled Product<p>Applications Labelled Tinidazole. Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.<br>References Miller, M.W., et al.: J. Med. Chem., 13, 849 (1970), Oderdea, G., et al.: Gut, 33, 1328 (1992),<br></p>Formula:C8H8D5N3O4SColor and Shape:NeatMolecular weight:252.3Rufinamide-d2
CAS:Controlled Product<p>Applications Labelled Rufinamide (R701552). Antiepileptic triazole derivative which decreases firing by neurons at sodium channels. Anticonvulsant.<br>References Cheung, W.K., et al.: Pharm. Res., 12, 1878 (1995), Cardot, J.-M., et al.: Biopharm. Drug Dispos., 19, 259 (1998), Palhagen, S., et al.: Epilepsy Res., 43, 115 (2001),<br></p>Formula:C10H6D2F2N4OColor and Shape:White To Light YellowMolecular weight:240.213-Dechloro-4-chloro Lamotrigine
CAS:Controlled Product<p>Impurity Lamotrigine EP Impurity G<br>Applications 3-Dechloro-4-chloro Lamotrigine (Lamotrigine EP Impurity G) is a potential impurity of Lamotrigine (L173250).<br>References Rees, R., et al.: J. Med. Chem., 15, 859 (1972), McNamara, J., et al.: Nature, 399, A15 (1999),<br></p>Formula:C9H7Cl2N5Color and Shape:NeatMolecular weight:256.09(4-(3-Methoxypropoxy)-3-methylpyridin-2-yl)methanol Hydrochloride
CAS:Controlled ProductFormula:C11H17NO3·HClColor and Shape:NeatMolecular weight:211.26 + 36.46Triclabendazole Sulfone
CAS:Controlled Product<p>Applications Triclabendazole Sulfone is a metabolite of Triclabendazole (T774175), the only anthelmintic drug, which is active against immature, mature and adult stages of fluke.<br>References Whelan, M., et al.: J. Chromato., 1275, 41 (2013); Barrera, S., et al.; Antimicrob. Agent. Chemother., 56, 3535 (2012);<br></p>Formula:C14H9Cl3N2O3SColor and Shape:Off-WhiteMolecular weight:391.66N-(3-(1H-imidazol-1-yl)propyl)-1-(4-fluorophenyl)-2,2-dimethylcyclopropane-1-carboxamide
CAS:Purity:98%Molecular weight:315.3919982910156N-Ethyl-N-methyl-3-vinylphenyl Carbamate
CAS:Controlled Product<p>Impurity Rivastigmine USP Related Compound F<br>Stability Light Sensitive<br>Applications A related compound of Rivastigmine (R541000), a cholinesterase inhibitor. Rivastigmine USP Related Compound F.<br></p>Formula:C12H15NO2Color and Shape:White SolidMolecular weight:205.252-(5-TETRAZOLYL)ETHANAMINE HCL
CAS:Formula:C3H8ClN5Purity:95.0%Color and Shape:CrystallineMolecular weight:149.584,4',4''-Methylidynetrisbenzonitrile (Letrozole Impurity)
CAS:<p>Impurity Letrozole EP Impurity B<br>Applications 4,4',4''-Methylidynetrisbenzonitrile (Letrozole EP Impurity B) is a Letrozole isomeric impurity.<br></p>Formula:C22H13N3Color and Shape:Off-WhiteMolecular weight:319.36[2-[5-(Aminomethyl)-2-methyl-1H-imidazol-1-yl]-5-chlorophenyl](2-fluorophenyl)-methanone Dihydrochloride
CAS:Controlled ProductFormula:C18H15ClFN3O• 2(HCl)Color and Shape:White To YellowMolecular weight:343.78Piracetam-d8
CAS:Controlled Product<p>Applications Labelled Piracetam (P500800). Nootropic.<br>References Gobert, J., et al.: J. Pharm. Belg., 27, 281 (1972), Oosterveld, W.J., et al.: Arzneim.-Forsch., 30, 1947 (1980), Chouinard, G., et al.: Psychopharmacol. Bull., 17, 129 (1981),<br></p>Formula:C6D8H2N2O2Color and Shape:NeatMolecular weight:150.21PD 312236, PD 312237 Mixture
CAS:<p>Applications PD 312236 is a pyranoside lactose conjugate degradation product of pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Lovdahl, M.J., et al.: J. Pharma. Biomed. Anal., 28, 917 (2002);<br></p>Formula:C20H35NO11Color and Shape:NeatMolecular weight:465.49Lamotrigine
CAS:Controlled Product<p>Applications An anticonvulsant. Inhibits glutamate release, possible through inhibition of Sodium, Potassium and Calcium currents. Used in treatment of bipolar depression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, A.A., et al.: Epilepsia, 27, 483 (1986), Grunze, et al.: Neuropsychobiology, 38, 131 (1998), Calabrese, J.R., et al.: J. Clin. Psychiatry, 60, 79 (1999),<br></p>Formula:C9H7Cl2N5Color and Shape:NeatMolecular weight:256.091'-Hydroxy Midazolam-β-D-glucuronide
CAS:Controlled Product<p>Applications The major metabolite of Midazolam (M343000(P)). Midazolam is an anesthetic; anticonvulsant; sedative; hypnotic. It is a positive allosteric modulator of the GABAA receptor.<br>References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)<br></p>Formula:C24H21ClFN3O7Color and Shape:White To Off-WhiteMolecular weight:517.891-Cyclopropyl-1H-benzo[d]imidazol-2(3H)-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:174.2030029296875Rivastigmine Tartrate Salt
CAS:Controlled ProductFormula:C14H22N2O2·C4H6O6Color and Shape:White To Off-WhiteMolecular weight:400.42rel-(R,R)-Voriconazole
CAS:Controlled Product<p>Applications The (R,R)-enantiomer of Voriconazole. An antifungal (systemic). An ergosterol biosynthesis inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997),<br></p>Formula:C16H14F3N5OColor and Shape:NeatMolecular weight:349.315-Methoxy-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-1H-benzo[d]imidazole
CAS:Controlled Product<p>Applications 5-Methoxy-2-(4-methoxy-3,5-dimethylpyridin-2-yl)-1H-benzo[d]imidazole is an impurity of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983), Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984), Morii, M., et al.: J. Biol. chem., 268, 21553 (1993), Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>Formula:C16H17N3O2Color and Shape:NeatMolecular weight:283.33N-(Benzyloxy)-5-methyl-2-phenyloxazole-4-carboxamide
CAS:Purity:98%Molecular weight:308.33700561523445-(5-Fluoro-1-methyl-1h-1,3-benzodiazol-2-yl)-2-methylaniline
CAS:Purity:95%Molecular weight:255.29600524902344(S)-N-Desethyl Oxybutynin Hydrochloride
CAS:Controlled Product<p>Applications (S)-Metabolite of the drug Oxybutynin. Used in the treatmentment of incontinence.<br>References Ehlert, F., et al.: Life Sci., 74, 355 (2003), Matsui-Sakata, A., et al.: Drug Metab. Pharmacokinet., 20, 187 (2005), Hegde, S., et al.: Br. J. Pharmacol., 147, S80 (2006), Tashiro, M., et al.: Br. J. Clin. Pharmacol., 61, 16 (2006),<br></p>Formula:C20H27NO3·ClHColor and Shape:NeatMolecular weight:365.891-(2-naphthylmethyl)-1H-benzimidazole-2-carbaldehyde
CAS:Purity:95.0%Molecular weight:286.3340148925781(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole
CAS:Purity:95.0%Molecular weight:345.42001342773443,4,5-Trimethoxybenzoic Acid
CAS:<p>Applications A metabolite of Trimebutine (T795605(P)), which is an opioid receptor agonist and an antispasmodic.<br>References Dieks, H., et al.: J. Labelled Comp. Radiopharm., 28, 1093 (1990), Delvaux, M., et al.: J. Int. Med. Res., 25, 225 (1997), Lavit, M., et al.: Arzneim.-Forsch., 50, 640 (2000),<br></p>Formula:C10H12O5Color and Shape:White To BeigeMolecular weight:212.20N-Nitroso Methyl Aniline Derivative
CAS:Formula:C14H11ClN2O2Color and Shape:WhiteMolecular weight:274.7023Letrozole Diacid Impurity
CAS:Controlled Product<p>Applications An impurity of Letrozole (L330100) which is a nonsteroidal aromatase inhibitor structurally related to Fadrozole.<br>References Bhatnagar, A.S., et al: J. Steroid Biochem. Mol. Biol., 37, 1021 (1990), Pfister, C.U., et al.: J. Pharm. Sci., 83, 520 (1994), Lipton, A., et al.: Cancer, 75, 2132 (1995).<br></p>Formula:C17H13N3O4Color and Shape:White To Off-WhiteMolecular weight:323.3(S)-Pregabalin Lactam
CAS:<p>Impurity Pregabalin EP impurity A<br>Applications (S)-Pregabalin Lactam is an impurity of (S)-Pregabalin (P704790) which is a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C8H15NOColor and Shape:WhiteMolecular weight:141.211H-Benzo[d]imidazole-5-carbohydrazide
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:176.1790008544922{5-[1-(benzylamino)cyclohexyl]-1H-tetrazol-1-yl}acetic acid
CAS:Purity:95.0%Molecular weight:315.377014160156252,4-Dichloro-b-[(2,4-dichlorophenyl)methoxy]benzeneethanamine
CAS:Controlled Product<p>Impurity Miconazole EP Impurity C<br>Stability Hygroscopic<br>Applications 2,4-Dichloro-β-[(2,4-dichlorophenyl)methoxy]benzeneethanamine (Miconazole EP Impurity C) is an impurity of Miconazole (M342500).<br>References DeNinno, M.P., J. Med. Chem., 33, 2950 (1990), MacKenzie, R., et al.: J. Med. Chem., 34, 2561 (1991), Katerinopoulos, H.E., et al.: Eur. J. Med. Chem., 30, 949 (1995),<br></p>Formula:C15H13Cl4NOColor and Shape:NeatMolecular weight:365.08Miconazole
CAS:<p>Applications Antifungal (topical).<br>References Godefroi, E.F., et al.: J. Med. Chem., 12, 784 (1969), Brugmans, et al.: Arch. Dermatol., 102, 428 (1970), Heel, R.C., et al.: Drugs, 19, 7 (1980),<br></p>Formula:C18H14Cl4N2OColor and Shape:WhiteMolecular weight:416.13(S)-4-Isopropyl-5,5-diphenyloxazolidin-2-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:281.35501098632811-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-imidazole
CAS:Purity:98%Molecular weight:284.17001342773441-(4-Fluoro-benzyl)-2-(pyrrolidin-3-ylmethoxy)-1H-benzoimidazole hydrochloride
CAS:Purity:95.0%Molecular weight:361.8500061035156Carbamazepine 10,11-Epoxide-d2 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Carbamazepine (C175840).<br>References Bellucci, G., et al.: J. Med. Chem., 30, 768 (1987), Johannessen, S., et al.: Ther. Drug. Monit., 27, 710 (2005), Bialer, M., et al.: Expert Opin. Invest. Drugs, 15, 637 (2006), Williams, J., et al.: J. Clin. Pharmacol., 46, 258 (2006),<br></p>Formula:C15H10D2N2O2Color and Shape:NeatMolecular weight:254.28N,N-Diphenyl-1H-imidazole-1-carboxamide
CAS:Purity:97.0%Color and Shape:Solid, No data available.Molecular weight:263.29998779296875
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