Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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(3S)-3-(2-Methylpropyl)-pentanedioic Acid 1-Methyl Ester
CAS:Controlled Product<p>Impurity Pregabalin Impurity 17<br>Applications (3S)-3-(2-Methylpropyl)-pentanedioic Acid 1-Methyl Ester (Pregabalin Impurity 17) is an impurity of Pregabalin (P704800), a GABA analogue used as an anticonvulsant.<br>References Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993); Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C10H18O4Color and Shape:NeatMolecular weight:202.252-Chlorobenzotrichloride
CAS:Controlled Product<p>Applications 2-Chlorobenzotrichloride is a chlorinated toluene with mutagenicity.<br>References Mineki, S. et al.: Mat. technol., 23, 413 (2005); Matsushita, H. et al.: Indust. Health., 17, 199 (1979);<br></p>Formula:C7H4Cl4Color and Shape:NeatMolecular weight:229.92Propyl Itraconazole
CAS:Controlled ProductFormula:C34H36Cl2N8O4Color and Shape:NeatMolecular weight:691.612-[2-(2-Methyl-4-nitroimidazol-1-yl)ethoxy]ethanol
CAS:Controlled ProductFormula:C8H13N3O4Color and Shape:NeatMolecular weight:215.213-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane Bromide
CAS:Controlled Product<p>Applications 3-Hydroxy-1-methyl-1-Azoniabicyclo[2.2.2]octane is an impurity in the synthesis of Clidinium Bromide (C576250), an anticholinergic. Used as an antispasmodic.<br>References Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Sanderson, H., et al.: Toxicol Lett., 187, 84 (2009),<br></p>Formula:C8H16BrNOColor and Shape:NeatMolecular weight:222.126-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline
CAS:Controlled Product<p>Applications 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline is a photochemical decomposition product of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Anderson, R., et al.: J. Pharma. Biomed. Anal., 13, 667 (1995); Anderson, R., et al: Am. Clin. Lab., 16, 25 (1997);<br></p>Formula:C15H10ClFN2Color and Shape:NeatMolecular weight:272.704,4'-(Bromomethylene)dibenzonitrile
CAS:Controlled Product<p>Applications 4,4'-(1-Bromomethyl)bis-benzonitrile (CAS# 69545-39-7) is a useful research chemical compound.<br></p>Formula:C15H9BrN2Color and Shape:NeatMolecular weight:297.1492,2'-Ethylenedianiline
CAS:Controlled Product<p>Applications 2,2'-Ethylenedianiline is used as a reagent to synthesize Oxcarbazepine (O869250), a broad-specturm, second-generation anticonvulsant drug that is used to treat partial and complex partial seizures in children and adults. 2,2'-Ethylenedianiline is also used as a reagent to prepare a series of triterpines (e.g. Lupeol [L474850]), compounds that have chemopreventative activity.<br>References Asmaa, M., et al.: Pac. J. Cancer Prevent., 15, 475 (2014); Kalis, M. & Huff, N.: Clin. Ther., 23, 680 (2001); Malke, S., et al.: Pharm. Sci., 69, 211 (2007); Schmidt, D. & Elger, C.: Epil. Beh., 5, 627 (2004)<br></p>Formula:C14H16N2Color and Shape:NeatMolecular weight:212.29Benzofuran-6-carboxylic Acid
CAS:Controlled Product<p>Applications Benzofuran-6-carboxylic Acid is a reagent in the development of potent LFA-1/ICAM antagonist SAR 118 as an opthalmic solution for treating dry eyes. Preparation of piperidinylpyrimidine derivatives as inhibitors of HIV-1 LTR activation.<br>References Zhong, M., et al.: ACS Med. Chem., 3, 203 (2012); Fujiwara, N., et al.: Bioorg. Med. Chem., 16, 9804 (2008)<br></p>Formula:C9H6O3Color and Shape:NeatMolecular weight:162.14ent-Voriconazole
CAS:Controlled Product<p>Impurity Voriconazole EP Impurity D; Voriconazole USP Related Compound B<br>Applications ent-Voriconazole (Voriconazole USP Related Compound B; Voriconazole EP Impurity D) is the (2S,3R) enantiomer in Voriconazole (V760000) drug substance.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gage, R., et al.: J. Pharm. Biomed. Anal., 17, 1449 (1998), Owens, P., et al.: Enantiomer, 4, 79 (1999), Pehourcq, F., et al.: Biomed. Chromatogr., 18, 719 (2004), Sellers, J., et al.: J. Pharm. Biomed. Anal., 41, 1088 (2006),<br></p>Formula:C16H14F3N5OColor and Shape:NeatMolecular weight:349.315,6-Dimethoxyindane-1,3-dione
CAS:Controlled ProductFormula:C11H10O4Color and Shape:NeatMolecular weight:206.1910,11-Dihydro Carbamazepine
CAS:Controlled ProductFormula:C15H14N2OColor and Shape:WhiteMolecular weight:238.28Varenicline-d2,15N2 Dihydrochloride
CAS:Controlled Product<p>Applications Varenicline-d2,15N2 Dihydrochloride, is the labelled dihydrochloride salt of Varenicline (V098492), a nicotinic α4β2 acetylcholine receptor partial agonist. Aids in smoking cessation.<br>References Benowitz, N., et al.: Clin. Pharmacol. Ther., 44, 23 (1988), Cohen, C., et al.: J. Pharmacol. Exp. Ther., 306, 407 (2003), Tapper, A., et al.: Science, 306, 1029 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Obach, R., et al.: Drug Metab. Disp., 34, 121 (2006),<br></p>Formula:C13H13D2Cl2N15N2Color and Shape:Light Beige SolidMolecular weight:288.18Triazolam-d3
CAS:Controlled Product<p>Applications Labelled Triazolam (T767380(M)). Triazolam in an hypnotic drug used in the short term treatment of insomnia.<br>References Lomen, P., et al.: J. Int. Med. Res., 4, 55 (1976), Allens, G.S., et al.: J. Int. Med. Res., 6, 343 (1978), Pakes, G.E., et al.: Drugs, 22, 81 (1981).<br></p>Formula:C17H9D3Cl2N4Color and Shape:NeatMolecular weight:346.232-Chloromethyl-4-methoxy-3-methylpyridine Hydrochloride
CAS:Controlled Product<p>Applications A pyridine derivative used in the preparation of anti-ulcerative agents and other pharmaceutical compounds.<br>References Kuehler, T.C. et al.: J. Med. Chem., 38, 4906 (1995);<br></p>Formula:C8H10ClNO·ClHColor and Shape:NeatMolecular weight:208.08Propantheline-d3 Iodide
CAS:Controlled Product<p>Applications Labelled Propantheline (P760900). Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.<br>References Levin, R. et al.: Neurol. Urodyn., 1, 221 (1982); Daniotti, S. et al.: Br. J. Pharmacol., 82, 305 (1984); Moller, J. et al .: Acta Med. Scand., 184, 201 (1968);<br></p>Formula:C23H27D3INO3Color and Shape:NeatMolecular weight:498.414-Hydroxy Midazolam-d5 Methanoate
CAS:Controlled Product<p>Applications A labelled metabolite of Midazolam (M343000).<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006),<br></p>Formula:C19H12D5ClFN3O2Color and Shape:NeatMolecular weight:378.84Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity
CAS:Controlled Product<p>Applications Itraconazole Desethylene-seco-piperazine Mono-N-formyl Impurity of Itraconazole (I937500). Itraconazole is an orally active antimycotic structurally related to Ketoconazole. Antifungal. It is a COVID19-related research product.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984), Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993),<br></p>Formula:C34H36Cl2N8O5Color and Shape:NeatMolecular weight:707.61N-Methyl Omeprazole-d3 (Mixture of isomers with the methylated nitrogens of imidazole)
CAS:Controlled Product<p>Applications Labelled Omeprazole (O635000) impurity.<br>References Allenmark, S., et al.: Anal. Biochem., 136, 293 (1984), Besancon, M., et al.: J. Biol. Chem., 272, 22438 (1997),<br></p>Formula:C18H18D3N3O3SColor and Shape:NeatMolecular weight:362.46
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