Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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N-Nitroso Albendazole (mixtures of regional isomers)
Controlled ProductFormula:C13H16N4O3SColor and Shape:NeatMolecular weight:616.712Trimebutine EP Impurity E-Nitroso
Controlled ProductFormula:C21H26N2O6Color and Shape:NeatMolecular weight:402.4412-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine Hydrochloride
CAS:Controlled Product<p>Impurity Omeprazole EP Impurity XI<br>Applications 2-(Chloromethyl)-4-methoxy-3,5-dimethylpyridine Hydrochloride (Omeprazole EP Impurity XI) is an intermediate in the production of the antiulcer agent Omeprazole.<br>References Roma, G., et al.: J. Med. Chem., 50, 2886 (2007), Hoffmann, S., et al.: Toxicol. Lett., 180, 9 (2008),<br></p>Formula:C9H12ClNO·ClHColor and Shape:WhiteMolecular weight:222.11N-Nitroso Aryl Lurasidone
CAS:Controlled ProductFormula:C11H12N4OSColor and Shape:NeatMolecular weight:248.316-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline
CAS:Controlled Product<p>Applications 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline is a photochemical decomposition product of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.<br>References Anderson, R., et al.: J. Pharma. Biomed. Anal., 13, 667 (1995); Anderson, R., et al: Am. Clin. Lab., 16, 25 (1997);<br></p>Formula:C15H10ClFN2Color and Shape:NeatMolecular weight:272.70Propyl Itraconazole
CAS:Controlled ProductFormula:C34H36Cl2N8O4Color and Shape:NeatMolecular weight:691.615,6-Dimethoxyindane-1,3-dione
CAS:Controlled ProductFormula:C11H10O4Color and Shape:NeatMolecular weight:206.19(R)-4,5-Dehydro Pregabalin
CAS:Controlled Product<p>Applications (R)-4,5-Dehydro Pregabalin is derived from rac 4,5-Dehydro Pregabalin (D230050), which is an impurity of the anti-convulsnat, Pregabalin.<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Formula:C8H15NO2Color and Shape:NeatMolecular weight:157.21N-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl] Rabeprazole Sulfide
CAS:Controlled Product<p>Applications Rabeprazole (R070500) N-aralkyl impurity.<br>References Fujisaki, H., et al.: Biochem. Pharmacol., 42, 321 (1991), Morri, M., et al.: J. Biol. Chem., 268, 21553 (1993), Pingili, R., et al.: Pharmazie, 60, 814 (2005),<br></p>Formula:C29H36N4O4SColor and Shape:NeatMolecular weight:536.692,5-Dichlorothiophen-3-yl Tioconazole Hydrochloride
CAS:Controlled ProductFormula:C16H12Cl4N2OS·ClHColor and Shape:NeatMolecular weight:458.62(3S)-1-[2-(3-Ethenyl-4-hydroxyphenyl)ethyl]-α,α-diphenyl-3-pyrrolidineacetamide
CAS:Controlled ProductFormula:C28H30N2O2Color and Shape:NeatMolecular weight:426.554-Hydroxy Midazolam-d5 Methanoate
CAS:Controlled Product<p>Applications A labelled metabolite of Midazolam (M343000).<br>References Ha, H., et al.: Ther. Drug Monit., 15, 338 (1993), Thummel, K., et al.: J. Pharmacol. Exp. Ther., 271, 557 (1994), Kim, R., et al.: Pharm. Res., 16, 408 (1999), Maurer, H., et al.: Anal. Bioanal. Chem., 381, 110 (2005), Smink, B., et al.: J. Anal. Toxicol., 30, 478 (2006),<br></p>Formula:C19H12D5ClFN3O2Color and Shape:NeatMolecular weight:378.84(S)-5,6-Dehydro Pregabalin
CAS:Controlled Product<p>Applications (S)-5,6-Dehydro Pregabalin is derived from rac 5,6-Dehydro Pregabalin (D230055), which is an impurity of the anti-convulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>Formula:C8H15NO2Color and Shape:NeatMolecular weight:157.21(S)-Aclidinium Bromide
CAS:Controlled Product<p>Applications (S)-Aclidinium Bromide is an isomer of Aclidinium Bromide (A190180) a novel long-acting antimuscarinic bronchodilator in phase II clinical trials for the treatment of chronic obstructive pulmonary disease (1,2).<br>References (1) Gupta, V. and Singh, D.: Expert Rev Respir Med. 6, 581 (2012)(2) De La Motte, S., et al.: Int. J. Clin. Pharmacol. Therap., 50,403 (2012)<br></p>Formula:C26H30BrNO4S2Color and Shape:Off-WhiteMolecular weight:564.554-Chloro-6-ethyl-5-fluoropyrimidine
CAS:Controlled Product<p>Applications A pyrimidine derivative used as a building block in the preparation of bio-active compounds such as broad-spectrum triazole antifungal agents.<br>References Butters, M. et al.: Org. Proc. Res. Dev., 5, 28 (2001); Tong, L. et al.: Zhong. Yao., 8, 280 (2010);<br></p>Formula:C6H6ClFN2Color and Shape:NeatMolecular weight:160.582,4-Dicyano-3-(2-methylpropyl)-pentanediamide (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygrscopic<br>Applications 2,4-Dicyano-3-(2-methylpropyl)-pentanediamide is an impurity of Pregabalin (P704800), a GABA (A602920) analogue used as an anticonvulsant.<br>References Hoekstra, M.S., et al.: Org. Proc. Rec. Deve., 1, 26 (1997); Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951); Gerlach, M., et al.: Brain Res., 741, 142 (1996); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)<br></p>Formula:C11H16N4O2Color and Shape:NeatMolecular weight:236.279-Acridinecarboxylic acid
CAS:Controlled Product<p>Applications 9-Acridinecarboxylic acid is used in the synthesis of short DNA-binding peptides.<br></p>Formula:C14H9NO2Color and Shape:YellowMolecular weight:223.23Propantheline-d3 Iodide
CAS:Controlled Product<p>Applications Labelled Propantheline (P760900). Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.<br>References Levin, R. et al.: Neurol. Urodyn., 1, 221 (1982); Daniotti, S. et al.: Br. J. Pharmacol., 82, 305 (1984); Moller, J. et al .: Acta Med. Scand., 184, 201 (1968);<br></p>Formula:C23H27D3INO3Color and Shape:NeatMolecular weight:498.41Butyl Itraconazole
CAS:Controlled ProductFormula:C35H38Cl2N8O4Color and Shape:NeatMolecular weight:705.632,5-Dichlorobenzoyl Cyanide
CAS:Controlled Product<p>Applications 2,5-Dichlorobenzoyl Cyanide is a reagent applied for research purposes<br>References Veerareddy, A., et al.: J. Heterocyclic Chem., 51, 1311 (2014)<br></p>Formula:C8H3Cl2NOColor and Shape:NeatMolecular weight:200.022
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