Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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Dehydrodeoxy donepezil
CAS:<p>Dehydrodeoxy donepezil is an analytical standard that is used in the manufacture of pharmaceuticals. It is a synthetic drug impurity, and its CAS number is 120013-45-8. Dehydrodeoxy donepezil can be found in the API impurity grade of various drugs, including those that are manufactured by Custom synthesis and natural synthesis. The pharmacopoeia states that dehydrodeoxy donepezil has a purity level of 98% or greater. This product can also be found as a metabolite in humans, with its half-life being approximately 40 minutes.</p>Formula:C24H29NO2Purity:Min. 95%Molecular weight:363.49 g/molSolifenacin EP impurity F succinate
CAS:<p>Solifenacin is an anti-cholinergic drug that has been shown to have a potent antagonistic effect on muscarinic receptors. It is used in the treatment of overactive bladder, urinary incontinence, and irritable bowel syndrome. Solifenacin succinate is a metabolite of solifenacin and it has been found to be an antagonist of M3 muscarinic receptors. The presence of solifenacin and its metabolites in wastewater can interfere with treatment processes by inhibiting the removal of other organic chemicals such as tamsulosin hydrochloride. Optimisation studies for solifenacin production have shown that famotidine can be used as a process aid to reduce solifenacin impurities. Famotidine is also an antagonist of M3 muscarinic receptors and can be used to remove solifenacin from wastewater. Analytes detected in wastewater samples include solifenacin, famot</p>Formula:C27H32N2O6Purity:Min. 95%Molecular weight:480.55 g/mol1-Deoxy-4-O-β-D-galactopyranosyl-1-[(4R)-4-(2-methylpropyl)-2-oxo-1-pyrrolidinyl]-β-D-fructopyranose/furanose
CAS:<p>Lactose conjugate degradation product of pregabalin</p>Formula:C20H35NO11Purity:Min. 95%Color and Shape:PowderMolecular weight:465.49 g/molN,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride
CAS:Controlled Product<p>N,N-Dimethylaminoethyl-a-(1-Hydroxycyclopentyl)phenylacetate hydrochloride (DMAEA) is a drug that is used as an ophthalmic. It has been shown to be safe and effective in patients with chronic open angle glaucoma, and it may also have some efficacy for the treatment of other conditions such as uveitis and retinal detachment. DMAEA is thought to work by binding to the DNA in the eye’s optic nerve cells and blocking the production of leukotrienes. This drug has also been shown to have anti-inflammatory properties.</p>Formula:C17H26ClNO3Purity:Min. 95%Color and Shape:PowderMolecular weight:327.85 g/mol2-Methoxy-5-methyL-N,N-bis(1-methyLethyL)-γ-phenyLbenzenepropanamine fumarate
CAS:<p>2-Methoxy-5-methyL-N,N-bis(1-methyLethyl)-gamma-phenyLbenzenepropanamine fumarate (DMXBPC) is an analgesic that has been shown to be a potent inhibitor of the cytosolic phospholipase A2 and is also cytotoxic. DMXBPC has significant cholinergic activity and can inhibit the synthesis of prostaglandins in the prostate gland. DMXBPC binds to the pyridine ring of DOPA and inhibits its conversion to dopamine. The enantiomers of DMXBPC have different effects on inhibition of phospholipase A2, with the (+) form being more potent than the (-) form. This is due to the fact that (+)DMXBPC binds more tightly to the enzyme than (-)DMXBPC does.</p>Formula:C23H33NOPurity:Min. 95%Molecular weight:339.51 g/mol2-Hydroxy-5-methyl-γ-phenylbenzenepropanol
CAS:<p>2-Hydroxy-5-methylphenylbenzenepropanol is an aliphatic phenol that is used as a treatment for benzene poisoning. It is also used as a precursor to other compounds, such as the chlorides and alkylates of 2-hydroxy-5-methylphenylbenzenepropanol. This compound can be synthesized by reacting ethyl benzoylacetate with diisopropylamine in the presence of oxygen and chlorine gas. It is often immobilized using nutrients, l-tartaric acid, or cinnamic acid.</p>Formula:C16H18O2Purity:Min. 95%Molecular weight:242.31 g/mol(S)-4-(2-Methylpropyl)-2-pyrrolidinone
CAS:Controlled Product<p>(S)-4-(2-Methylpropyl)-2-pyrrolidinone is a lactam that has been synthesized in the laboratory. It is an organic solvent that is used in the synthesis of other compounds. The compound has a potential for producing impurities, such as isopropyl and phosphite, during synthesis. (S)-4-(2-Methylpropyl)-2-pyrrolidinone can be synthesized by reacting 2-methylpropionic acid with one equivalent of methylamine. This reaction takes place in an organic solvent and requires kinetic control to avoid side reactions.</p>Formula:C8H15NOPurity:Min. 95%Color and Shape:PowderMolecular weight:141.21 g/molZolazepam
CAS:<p>Zolazepam (CI 716), a pyrazole and diazazone derivative, is a benzodiazepine-like veterinary anesthetic.</p>Formula:C15H15FN4OColor and Shape:SolidMolecular weight:286.3Abeprazan
CAS:<p>Abeprazan is a potassium-competitive acid blocker targeting acid-related diseases without acid activation.</p>Formula:C19H17F3N2O3SPurity:98%Color and Shape:SolidMolecular weight:410.41Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurity:99.84%Color and Shape:Clear In WaterMolecular weight:367.4(R,R)-Glycopyrrolate
CAS:<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>Formula:C19H28BrNO3Purity:98%Color and Shape:SolidMolecular weight:398.34Metopimazine
CAS:<p>Metopimazine is a selective and peripherally restricted dopamine D3 and D2 receptors antagonist.</p>Formula:C22H27N3O3S2Purity:98%Color and Shape:SolidMolecular weight:445.6Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formula:C15H16Cl3N3O2Purity:99.75% - 99.79%Color and Shape:Colorless SolidMolecular weight:376.67Orphenadrine
CAS:<p>Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner,</p>Formula:C18H23NOPurity:98.91% - 99.11%Color and Shape:SolidMolecular weight:269.38Morinidazole
CAS:<p>Morinidazole has antibacterial properties for researching anaerobic infections like appendicitis and PID.</p>Formula:C11H18N4O4Purity:98.92% - 99.82%Color and Shape:SolidMolecular weight:270.29(1-Nitroethyl)benzene
CAS:<p>(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.</p>Formula:C8H9NO2Purity:Min. 95%Color and Shape:PowderMolecular weight:151.16 g/mol5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone
CAS:<p>5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is a hydroxide that is obtained by the reflux of 4-hydroxybenzaldehyde with an alkali metal hydroxide. It can be used in the synthesis of benzylated donepezil hydrochloride. 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone condenses with pyridinecarboxaldehyde to produce 1-(4'-pyridylmethylene)indane. This reaction produces a mixture of products, including benzoic acid and the indane derivative.</p>Formula:C17H15NO3Purity:Min. 95%Molecular weight:281.31 g/molPantoprazole sulphide
CAS:<p>Pantoprazole sulphide is a benzimidazole derivative that has been synthesized in an asymmetric synthesis. The purified compound was characterized by its nmr spectra, which showed the presence of the carboethoxy group and the chromatographic method. The compound belongs to a family of inhibitors known as benzimidazole derivatives and has shown inhibitory activity against a number of bacterial species including Staphylococcus aureus, Clostridium perfringens, and Mycobacterium tuberculosis. Pantoprazole sulphide has been used as an inhibitor to treat gastric acid pump disorders such as Zollinger-Ellison syndrome. It is also used for treating pathological conditions such as duodenal ulcers or gastroesophageal reflux disease.</p>Formula:C16H15F2N3O3SPurity:Min. 95%Color and Shape:PowderMolecular weight:367.37 g/mol(S)-Rabeprazole sodium
CAS:<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>Formula:C18H21N3O3S•NaPurity:Min. 95%Molecular weight:382.43 g/molTroriluzole
CAS:<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>Formula:C15H16F3N5O4SPurity:97.14%Color and Shape:SolidMolecular weight:419.38
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