Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8901 products of "Purines and Pyrimidine Derivatives"
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4,6-Dihydroxypyrazolo[3,4-d]pyrimidine-13C,15N2
CAS:Controlled Product<p>Applications A labelled metabolite of Allopurinol.<br>References Marro, P., et al.: Brain Res., 650, 9 (1994), Abramov, A., et al.: J. Neurosci., 27, 1129 (2007), Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007),<br></p>Formula:CC4H415N2N2O2Color and Shape:White To BeigeMolecular weight:155.094-(3,4-dimethylphenyl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:365.4330139160156Succinimide
CAS:<p>Applications Succinimide is a reagent that is used in the synthesis of Lumiflavin (L473900), which is a toxic photolysis product of vitamin B2 (R415000).<br>References Zhao, X. et al.: Chemosphere, 63, 1116 (2006); Litke, S.V. et al.: Khim. Fiz., 10, 48 (1991); Ye, W. et al.: Guang. Yaox. Xueb., 12, 175 (1996);<br></p>Formula:C4H5NO2Color and Shape:White To Off-WhiteMolecular weight:99.09Didesmethyl Zolmitriptan (90%)
CAS:Controlled Product<p>Applications A metabolite of Zolmitriptan (Z639000).<br>References Buckingham, J., et al.: J. Med. Chem., 38, 3566 (1995),<br></p>Formula:C14H17N3O2Purity:90%Color and Shape:NeatMolecular weight:259.30Thyroxine-13C6 4'-O-β-D-Glucuronide Disodium Salt
CAS:Controlled ProductFormula:C1513C6H17I4NNa2O10Color and Shape:NeatMolecular weight:1002.912,4,5,6-Tetraaminopyrimidine Sulfate
CAS:Controlled Product<p>Applications Intermediate in the production of Methotrexate<br>References Chiosis, G., et al.: Bioorg. Med. Chem., 10, 3555 (2002), Palanki, M., et al.: J. Med. Chem., 50, 4279 (2007), Zav'yalov, S., et al.: Pharm. Chem. J., 42, 51 (2008),<br></p>Formula:C4H8N6·H2O4SColor and Shape:NeatMolecular weight:238.22N-Methylguanidine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications N-Methylguanidine is an alkylated guanidine which shows inhibitory action against trypsin catalysis. N-Methylguanidine inhibited metabolism of certain hepatic drugs that was mediated by cytochrome P 450 protein in human liver microsome and hepatocyte.<br>References Inagami, T. et al.: Biochemistry, 7, 4045 (1968); Hanada, K. et al.: Nephron, 103, 179 (2006);<br></p>Formula:C2H8ClN3Color and Shape:NeatMolecular weight:109.56(6-Benzhydryloxycarbonylamino-purin-9-yl)-acetic acid
CAS:Purity:97.0%Color and Shape:SolidMolecular weight:403.398010253906257-BROMO-2-(3-(PYRIMIDIN-2-YL)PHENETHYL)ISOINDOLIN-1-ONE
CAS:Purity:95.0%Molecular weight:394.2720031738281Telbivudine
CAS:Controlled Product<p>Applications Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.<br>References Standring, D.N., et al.: Antiviral. Chem. Chemother., 12, 119 (2001), Hernandez-Santiago, B., et al.: Antimicrob. Agents Chemother., 46, 1728 (2002), Lai, C.-L., et al.: Hepatology, 40, 719 (2004), Han, S.-H.B., et al.: Expert Opin. Invest. Drugs, 14, 511 (2005),<br></p>Formula:C10H14N2O5Color and Shape:White To Off-WhiteMolecular weight:242.234-([1,1'-Biphenyl]-4-yl)pyrimidin-2-amine
CAS:Purity:95+%Color and Shape:SolidMolecular weight:247.30099487304688Methotrexate-d3 Hexaglutamate Trifluoroacetic Acid Salt
CAS:Controlled Product<p>Applications Methotrexate-d3 Hexaglutamate is the isotope labelled analog of Methotrexate Hexaglutamate (M260745); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C45H54D3N13O20•x(C2HF3O2)Color and Shape:NeatMolecular weight:1103.03114023-Des[2-(Dimethylamino)ethyl] Zolmitriptan 3-Acetic Acid
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications The indole acetic acid metabolite of Zolmitriptan (Z639000) formed by human hepatocytes.<br>References Wild, M.J. et al.: Xenobiotica, 29, 847 (1999);<br></p>Formula:C14H14N2O4Color and Shape:NeatMolecular weight:274.27N-(2-CHLORO-5-METHOXYPYRIMIDIN-4-YL)-1H-INDAZOL-6-AMINE
CAS:Purity:95.0%Molecular weight:275.700012207031254-(3,4-dimethylphenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:281.3800048828125N-(4-((4-Chloro-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)thio)phenyl)cyclopropanecarboxamide
CAS:Purity:95.0%Molecular weight:400.89001464843753,5,3',5'-Tetraiodo Thyrolactic Acid (~90%)
CAS:Controlled Product<p>Stability Hygroscopic, Temperature sensitive<br>Applications 3,5,3',5'-Tetraiodo Thyrolactic Acid is a thyroid hormone analogue. A Thyroxine (T425600) analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989); Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992); Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999); Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002);<br></p>Formula:C15H10I4O5Purity:~90%Color and Shape:BeigeMolecular weight:777.85
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