Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8902 products of "Purines and Pyrimidine Derivatives"
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N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:277.33099365234375(2R,3R,4R,5R)-2-(2-AMINO-9H-PURIN-9-YL)-5-(HYDROXYMETHYL)-3-METHYLTETRAHYDROFURAN-3,4-DIOL
CAS:Purity:95.0%Molecular weight:281.2720031738281Methopterine (>90%)
CAS:Controlled Product<p>Impurity Methotrexate EP Impurity C; Methotrexate USP Related Compound C<br>Applications Methopterine (Methotrexate EP Impurity C) is a Folic acid (F680300) analogue. Methopterine is effective in the treatment of ectopic pregnancy. Methotrexate USP Related Compound C<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McNamara, P., et al.: Drug Metab. Dispos., 20, 302 (1992), Soldin, O., et al.: Ther. Drug Monit., 24, 1 (2002), Nicoli, S., et al.: J. Pharm. Biomed. Anal., 41, 994 (2006),<br></p>Formula:C20H21N7O6Purity:>90%Color and Shape:NeatMolecular weight:455.429-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one
CAS:Purity:97%Molecular weight:270.2200012207031LY-338979
CAS:<p>Applications LY 338979 is a metabolite of the antifolate Pemetrexed (P219500).<br>References Woodland, J.M. et al.: Drug Metab. Dispos., 25, 693 (1997);<br></p>Formula:C20H21N5O7Color and Shape:NeatMolecular weight:443.415-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide
CAS:Controlled Product<p>Applications 5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide is a metabolite of Temozolomide (T017775); an imidazotetrazine alkylating agent and antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997); Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999); Hait, W., et al.: Cancer Res., 69, 1263 (2009); Wang, Y., et al.: J. Org. Chem., 62, 7288 (1997)<br></p>Formula:C6H9N5O2Color and Shape:Off-WhiteMolecular weight:183.17N-Desmethoxypropyl Prucalopride
CAS:Controlled Product<p>Applications N-Desmethoxypropyl Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.<br>References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),<br></p>Formula:C14H18ClN3O2Color and Shape:NeatMolecular weight:132.201Memantine Lactose Adduct
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A lactose adduct of Memantine (M218000). Intermediate in the synthesis of reducing carbohydrate Adamantane amines for use in treating Gram positive or Gram negative bacteria infections.<br>References Kustimur, et al.: Chinese Med. J., 116, 633 (2003),<br></p>Formula:C24H41NO10Color and Shape:NeatMolecular weight:503.582-Amino-6-(5-methylfuran-2-yl)-5-nitropyrimidin-4-yl 4-methylbenzenesulfonate
CAS:Purity:97%Molecular weight:390.36999511718753-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester
CAS:<p>Impurity Allopurinol EP Impurity E / Allopurinol USP Related Compound E<br>Applications 3-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester (Allopurinol EP Impurity E) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.<br>References Nicolin, A. et al.: Cancer, Chemother. Rep., 57, 3 (1973); Bonmassar, E. et al.: Cancer Res., 35, 1957 (1975)<br></p>Formula:C7H9N3O3Color and Shape:WhiteMolecular weight:183.16N-Desmethyl Zolmitriptan
CAS:<p>Impurity Zolmitriptan USP Related Compound A<br>Stability Hygroscopic<br>Applications A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.<br>References Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004), Srinivasu, M., et al.: J. Pharm. Biomed. Anal., 37, 453 (2005),<br></p>Formula:C15H19N3O2Color and Shape:NeatMolecular weight:273.33Methyl 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylate
CAS:Controlled ProductFormula:C17H18N2O3SColor and Shape:NeatMolecular weight:330.44-(Tert-butyl)-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)benzamide
CAS:Purity:98%Molecular weight:438.54998779296875(S)-Tenofovir Disoproxil Fumarate
CAS:Controlled Product<p>Impurity Tenofovir Disoproxil USP Related Compound A<br>Applications The S-enantiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate (T018505(P)), which is an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor and used as an anti-HIV agent.Tenofovir Disoproxil USP Related Compound A.<br>References Shaw, J. P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)<br></p>Formula:C19H30N5O10P·C4H4O4Color and Shape:White SolidMolecular weight:635.52N-(3,4-Dimethoxyphenethyl)formamide
CAS:Controlled Product<p>Applications N-(3,4-Dimethoxyphenethyl)formamide is an impurity of Tetrabenazine (T284000), an antipsychotic.<br>References Schwartz, D., et al.: Biochem. Pharmacol., 15, 645 (1966),<br></p>Formula:C11H15NO3Color and Shape:NeatMolecular weight:209.242N'-Methyl-N,N-diphenylurea
CAS:<p>Impurity Temozolomide USP Related Compound B<br>Applications N'-Methyl-N,N-diphenylurea is used in the stabilization of thermal propellants. Temozolomide USP Related Compound B.<br>References Bohn, M. et al.: Prop. Exp. Pyro.,et al.: 19, 266 (1994); Muthurajan, H. et al.: J. Hazard. Mat., 133, 30 (2006);<br></p>Formula:C14H14N2OColor and Shape:NeatMolecular weight:226.272-Chloro-4-(3-pyridin-4-yl-ureido)benzenesulfonylchloride hydrochloride
CAS:Formula:C12H10Cl3N3O3SPurity:98%Color and Shape:SolidMolecular weight:382.643-Nitropyridine
CAS:Controlled Product<p>Applications Used in the novel synthesis of biologically active nitro heterocyclic compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pawar, N., et al.: Eur. J. Pharm. Sci., 21, 115 (2004), Badgujar, D., et al.: J. Sci. Ind. Res., 66, 250 (2007),<br></p>Formula:C5H4N2O2Color and Shape:NeatMolecular weight:124.10
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