Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8892 products of "Purines and Pyrimidine Derivatives"
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6,6'-Binicotinic Acid
CAS:Controlled Product<p>Applications A Nicotinic acid (N429250) derivative for treatment of hypercholesterolemia and hyperlipidemia and cardiovascular disease.<br>References Hales, N.J., et al.: J. Med. Chem., 36, 3853 (1993),<br></p>Formula:C12H8N2O4Color and Shape:NeatMolecular weight:244.20N-(9-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
CAS:Purity:98%Molecular weight:373.343994140625Rizatriptan
CAS:<p>Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.</p>Formula:C15H19N5Purity:99.74%Color and Shape:SolidMolecular weight:269.354-(thiophen-2-yl)-6-(3,4,5-trimethoxyphenyl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:343.3999938964844Tenofovir Diphosphate Triethylamine Salt (Mixture of Diastereomers)
CAS:<p>Stability Very Hygroscopic<br>Applications A metabolite of Tenofovir (T018500).<br>References Hazra, R., et al.: Antimicrob. Agents Chemother., 48, 124 (2004), Piketty, C., et al.: Antivir. Ther., 11, 213 (2006), Molto, J., et al.: Ther. Drug Monit., 29, 648 (2007),<br></p>Formula:C9H16N5O10P3·C6H15NColor and Shape:Off-White To Light YellowMolecular weight:447.171-Methyl-nicotinamide Iodide
CAS:Controlled Product<p>Applications A nicotinic acid derivative which shows a dopaminergic neurotoxicity.<br>References Rollema, H., et al.: J. Med. Chem., 33, 2221 (1990),<br></p>Formula:C7H9IN2OColor and Shape:NeatMolecular weight:264.064,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
CAS:Purity:98.0%Molecular weight:349.1700134277344N-(2-Chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:287.755-(1-Biphenyl-4-yl-1H-tetrazol-5-yl)-4-methyl-pyrimidin-2-ylamine
CAS:Color and Shape:SolidMolecular weight:329.36700439453125Allopurinol-d2
CAS:Controlled Product<p>Applications Labelled xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Benezra, S.A., et al.: Anal. Profiles Drug Subs., 7, 1, (1978), Dalbeth, N., et al.: Rheumatology, 44, 1090 (2005), Dinarello, C., et al.: J. Exp. Med., 201, 1355 (2005),<br></p>Formula:C52H2H2N4OColor and Shape:Light BrownMolecular weight:138.125-Acetylamino-6-amino-3-methyluracil Hydrate
CAS:Controlled Product<p>Applications Metabolite of Caffeine (C080100).<br>References Wong, P., et al.: J. Pharm. Biomed. Anal., 28, 693 (2002), Nyeki, A., et al.: Brit. J. Clin. Pharmacol., 55, 62 (2003), Jetter, A., et al.: Eur. J. Clin. Pharmacol., 65, 411 (2009),<br></p>Formula:C7H12N4O4Color and Shape:NeatMolecular weight:216.193-Methyl-1H-purine-2,6(3H,7H)-dione
CAS:Formula:C6H6N4O2Purity:95%Color and Shape:Solid, Light yellow powderMolecular weight:166.14Isoguanosine Hydrate
CAS:Controlled Product<p>Applications A useful synthetic intermedate. A naturally occuring, biologically active isomer of guanosine. Reported to stimulate the accumulation of cyclic-AMP in the brain. It is an inhibitor of IMP pyrophosphorylase, and its 5’-di and -tri-phosphates inhibit glutamic acid dehydrogenase. May contain approximately 0.6 moles of water.<br>References Divakar, K.J., et al.: J. Chem. Soc. Perkin Trans., 1, 771 (1991), Montsch, H.H., et al: Biochemistry, 14, 5593 (1975), Hagen, C.: Biochim. Biophys. Acta., 293, 105 (1973), Huang, M., et al.: J. Med. Chem., 15, 462 (1972)<br></p>Formula:C10H13N5O5·H2OColor and Shape:NeatMolecular weight:301.261,2,3,9-Tetrahydro-9-methyl-4H-carbazol-4-one
CAS:<p>Impurity Ondansetron EP Impurity C<br>Applications 1,2,3,9-Tetrahydro-9-(methyl-d3)-4H-carbazol-4-one (Ondansetron EP Impurity C) is used in the preparation of 5-HT3 modulators useful in the treatment and prevention of 5-HT3 receptor-mediated diseases. 1,2,3,9-Tetrahydro-9-methyl-4H-carbazol-4-one is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Huang, W. et al.: Zhong. Yao. Dax. Xueb., 30, 1 (1999); Kim, M. et al.: Heterocycles, 45, 2041 (1997); Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011);<br></p>Formula:C13H13NOColor and Shape:Off-WhiteMolecular weight:199.25Chloromethyl Ethyl Carbonate
CAS:Controlled Product<p>Applications A reagent used in the preparation of hepatitis C virus NS3 protease inhibitors and PMPA prodrugs with antiretroviral activity.<br>References Sheng, X. et al.: Bioorg, Med. Chem. Lett., 169, 3453 (2009); Arimilli, M.N. et al.: Antiviral Chem. Chemother., 8, 557 (1997);<br></p>Formula:C4H7ClO3Color and Shape:Colourless OilyMolecular weight:138.556,6’-Methylenebis[(3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one(Ondansetron Impurity B)
CAS:<p>Impurity Ondansetron EP Impurity B<br>Applications Ondansetron EP Impurity B.<br></p>Formula:C37H38N6O2Color and Shape:NeatMolecular weight:598.74(6-Methoxy-2-methylsulfanyl-pyrimidin-4-yl)-piperidin-4-yl-amine hydrochloride
CAS:Purity:95.0%Molecular weight:290.809997558593752-Chloro-N-piperidin-4-ylpyrimidin-4-amine hydrochloride
CAS:Purity:97.0%Molecular weight:249.139999389648444-([1,1'-Biphenyl]-4-yl)-6-chloro-2-phenylpyrimidine
CAS:Purity:95.0%Molecular weight:342.8299865722656
![6,6’-Methylenebis[(3RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carba…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FM303950.webp&w=3840&q=75)
![4-([1,1'-Biphenyl]-4-yl)-6-chloro-2-phenylpyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF053935.webp&w=3840&q=75)