Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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Carvedilol
CAS:Controlled Product<p>Applications Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996);<br></p>Formula:C24H26N2O4Color and Shape:WhiteMolecular weight:406.473-[2-(3,4-dimethoxyphenyl)ethyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one
CAS:Purity:98%Molecular weight:342.41Dolutegravir Sodium
CAS:<p>Applications Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011)<br></p>Formula:C20H18F2N3O5·NaColor and Shape:NeatMolecular weight:441.36Gabapentin Enacarbil Sodium Salt
CAS:Controlled Product<p>Applications Gabapentin enacarbil is a prodrug of the anticonvulsant gabapentin (G117250).<br>References Cundy, K., et al.: J. Pharmacol. Exp. Ther., 311, 315 (2004); Lal, R., et al.: Clin. Ther., 31, 1776 (2009)<br></p>Formula:C16H26NO6·NaColor and Shape:NeatMolecular weight:351.37Tert-Butyl 4-chloro-2-morpholino-5H-pyrrolo[2,3-d]pyrimidine-7(6H)-carboxylate
CAS:Purity:95.0%Molecular weight:340.80999755859375rac-trans-Ambroxol-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Bromohexine. Ambroxol Hydrochloride is a bronchosecretolytic drug.<br>References Jauch, R., et al.: Arzneim-Forsch., 13, 474 (1963)<br></p>Formula:C13H13D5Br2N2OColor and Shape:NeatMolecular weight:383.131-(10H-Phenothiazin-2-yl)propan-1-one
CAS:Purity:95%Color and Shape:SolidMolecular weight:255.339996337890622-Picoline
CAS:Controlled Product<p>Applications 2-Picoline is used as a reagent in the synthesis of 2-Picolineborane, a non-toxic alternative to sodium borohydride for the labelling of oligosaccharides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Renee Ruhaak, L., et al.: Proteomics, 10, 2330 (2010)<br></p>Formula:C6H7NColor and Shape:NeatMolecular weight:93.13Levofloxacin-d3 Sodium Salt
CAS:Controlled Product<p>Applications Levofloxacin-d3 Sodium Salt, is the labeled analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Formula:C18H16D3FN3NaO4Color and Shape:NeatMolecular weight:386.375-(Benzo[1,3]-dioxol-5yl)-picolinic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:243.21800231933594Amoxapine
CAS:<p>Applications Antidepressant.<br>References Takahashi, R., et al.: J. Int. Med. Res., 7, 7 (1979), Jue, S.G., et al.: Drugs 24, 1 (1982)<br></p>Formula:C17H16ClN3OColor and Shape:White To Light BeigeMolecular weight:313.784-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid
CAS:<p>Applications An impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.<br>References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)<br></p>Formula:C21H16Cl2N2O3Color and Shape:NeatMolecular weight:415.27Propoxyphenyl Thioaildenafil
CAS:Controlled Product<p>Applications Propoxyphenyl Thioaildenafil is an analogue of Thioaildenafil (T344365). Propoxyphenyl Thioaildenafil is a phosphodiesterase-5 inhibitor (PDE-5) that has been found in health supplements.<br>References Kee, C., Ge, X., Koh, H., Low, M.: J. Pharmaceut. Biomed., 70, 265 (2012)<br></p>Formula:C24H34N6O3S2Color and Shape:NeatMolecular weight:518.7Tricyclazole
CAS:Controlled Product<p>Applications Tricyclazole is an common active ingredient in several commercial fungicide products used to control rice blast fungus, in transplanted and direct-seeded rice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dhingani, J.C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Jeong, S.A., et al.: Bull. Environ. Contamin. Toxicol., 89, 1181 (2012);<br></p>Formula:C9H7N3SColor and Shape:BeigeMolecular weight:189.244-Demethoxy-4-hydroxy Apixaban
CAS:Controlled Product<p>Applications 4-Demethoxy-4-hydroxy Apixaban is a metabolite of Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Formula:C24H23N5O4Color and Shape:NeatMolecular weight:445.476-fluoro-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:259.299987792968751-(pyridin-3-ylmethyl)-1H-benzimidazole-5-carboxylic acid
CAS:Purity:95.0%Molecular weight:253.26100158691406Linagliptin
CAS:<p>Applications Linagliptin is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Formula:C25H28N8O2Color and Shape:White To OrangeMolecular weight:472.54OSI-420, Free Base (Desmethyl Erlotinib)
CAS:Controlled ProductFormula:C21H21N3O4Color and Shape:NeatMolecular weight:379.414-Diphenylmethoxypiperidine hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications 4-Diphenylmethoxypiperidine, HCl<br></p>Formula:C18H21NO·ClHColor and Shape:WhiteMolecular weight:303.832-(4-Chlorophenoxy)aniline
CAS:Controlled Product<p>Applications Amoxapine impurity.<br>References Matsuo, M., et al.: Chem. Pharma. Bull., 33, 4409 (1985),<br></p>Formula:C12H10ClNOColor and Shape:NeatMolecular weight:219.67Sulindac
CAS:Controlled Product<p>Applications Sulindac is a non-steroidal anti-inflammatory drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bjorkman., et al.: Am. J. Med., 105, 17S (1998), Thakur, et al.: Am. J. Hypertens., 12, 925 (1999),<br></p>Formula:C20H17FO3SColor and Shape:Yellow To Dark OrangeMolecular weight:356.41Ofloxacin
CAS:<p>Applications Ofloxacin is a fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990);<br></p>Formula:C18H20FN3O4Color and Shape:Off-WhiteMolecular weight:361.37Meloxicam
CAS:<p>Applications Preferential cyclooxygenase (COX-2) inhibitor. Sudoxicam and Meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hawkey, C., et al.: Br. J. Rheumatol., 35, Suppl. 1, 1 (1996), Fleischmann, R., et al.: Expert Opin. Pharmacother., 3, 1501 (2002),<br></p>Formula:C14H13N3O4S2Color and Shape:Light YellowMolecular weight:351.40(6,7-Dimethyl-3-phenyl-quinoxalin-2-yl)-phenyl-methanone
Purity:95.0%Molecular weight:338.4100036621094(2R,3S)-rel-Nadolol-de(N-tert-butyl)methoxy
<p>Impurity Nadolol EP Impurity B<br>Stability Hygroscopic<br>Applications (2R,3S)-rel-Nadolol-de(N-tert-butyl)methoxy is an impurity of Nadolol (N201050), a β-Adrenergic blocker. Antihypertensive; antianginal.<br>References Dreyfuss, J., et al.: J. Clin. Pharmacol., 17, 300 (1977); Sibley, P.L., et al.: Toxicol. Appl. Pharmacol., 44, 379 (1978); Slusarek, L., et al.: Anal. Profiles Drug Subs., 9, 455 (1980)<br></p>Formula:C14H20O5Color and Shape:NeatMolecular weight:268.30Ivacaftor Carboxylic Acid Lactone
CAS:Controlled ProductFormula:C24H24N2O4Color and Shape:NeatMolecular weight:404.464-Hydroxy Omeprazole Sulfide
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications An intermediate in the preparation of Omeprazole metabolites.<br>References Hoffmann, K., et al.: Drug Metab. Disposition, 14, 341 (1986), Andersson, T., et al.: Brit. J. Clin. Pharmacol., 36, 521 (1993),<br></p>Formula:C16H17N3O2SColor and Shape:NeatMolecular weight:315.395-(2,6-DIMETHOXYPHENYL)-1-(4-FLUOROPHENYL)-1H-PYRAZOLE-3-CARBOXYLIC ACID
Purity:90.0%Molecular weight:342.325988769531251-Methylindazole-3-carboxylic Acid (Granisetron Impurity D)
CAS:Controlled Product<p>Impurity Granisetron EP Impurity D<br>Applications Granisetron Impurity D.<br>References Bermudez, J., et al.: J. Med. Chem., 33, 1924 (1990),<br></p>Formula:C9H8N2O2Color and Shape:Off White SolidMolecular weight:176.172-[5-fluoro-2-(pyridin-3-yl)-1H-indol-3-yl]ethan-1-amine hydrochloride
CAS:Purity:95.0%Molecular weight:291.75Tert-Butyl N-[1-(quinazolin-4-yl)piperidin-4-yl]methylcarbamate
CAS:Molecular weight:342.44299316406254-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 4-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride (cas# 106261-49-8) is a compound useful in organic synthesis.<br></p>Formula:C13H18N2O2·2ClHColor and Shape:NeatMolecular weight:307.221-(3-Carboxypropyl)-3,7-dimethylxanthine
CAS:Controlled Product<p>Applications A metabolite of Pentoxifylline (P276500).<br>References Yamaoka, K., et al.: J. Pharmacokin. Biopharm., 6, 165 (1978), Cottam, H.B., et al.: J. Med. Chem., 39, 2 (1996), Janvilisri, T., et al.: J. Biol. Chem., 278, 20645 (2003),<br></p>Formula:C11H14N4O4Color and Shape:NeatMolecular weight:266.253-(3-Methoxyphenyl)-1-(p-tolyl)-1H-pyrazole-4-carboxylic acid
CAS:Purity:98%Molecular weight:308.33700561523443-acetyl-6-chloro-4-(4-chlorophenyl)quinolin-2(1H)-one
CAS:Purity:95.0%Molecular weight:332.179992675781253-acetyl-6-fluoro-4-(4-fluorophenyl)quinolin-2(1H)-one
CAS:Purity:95.0%Molecular weight:299.27700805664065,7-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.36999511718754-bromo-2-(5-pyridin-3-yl-4,5-dihydro-1H-pyrazol-3-yl)phenol
CAS:Purity:95.0%Molecular weight:318.174011230468752-(1-Nitroso-4-piperidinyl)-1H-benzimidazole
CAS:Controlled ProductFormula:C12H14N4OColor and Shape:NeatMolecular weight:230.2662-(5-amino-3-methyl-1H-pyrazol-1-yl)-6-phenylpyrimidin-4(3H)-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:267.2919921875
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