Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4948 products of "Steroids and Derivatives"
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Danazol
CAS:Controlled Product<p>Applications Danazol is an anterior pituitary supressant. Danazol is an anabolic steroid derivative of ethisterone, with mild androgenic side effects (an impeded androgen). Antigonadotropin.<br>References Ahn, Y.S., et al.: N. Engl. J. Med., 308, 1396 (1983),<br></p>Formula:C22H27NO2Color and Shape:White To Light YellowMolecular weight:337.46Prednisolone 17-Acetate
CAS:Controlled Product<p>Applications Prednisolone 17-Acetate is an intermediate in the preparation of anti-inflammatory drugs.<br>References Yoon, Kyoung-Jin, et al.: Steroids, 60(7), 445-51 (1995);Uszycka-Horawa, Teresa, et al.: Pol., PL 161012 B1 19930531 (1993)<br></p>Formula:C23H30O6Color and Shape:NeatMolecular weight:402.48Dexamethasone-d5
CAS:Controlled Product<p>Applications A glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formula:C222H5H24FO5Color and Shape:NeatMolecular weight:397.494β-Hydroxy Cholesterol-d7
CAS:Controlled Product<p>Applications 4β-Hydroxy Cholesterol-d7 is a labelled metabolite of Cholesterol. It is formed from Cholesterol by the drug-metabolizing enzyme cytochrome P 450 3A4. A potential ligand for the nuclear receptor LXR and also a new endogenous CYP3A marker.<br>References Breuer, O., et al.: J. Lipid Res., 36, 2275 (1995), Pikuleva, I., et al.: J. Biol. Chem., 273, 18153 (1998), Chawla, A., et al.: Science, 294, 1866 (2001), Bodin, K., et al.: J. Biol. Chem., 276, 38685 (2001),<br></p>Formula:C27H39D7O2Color and Shape:Off WhiteMolecular weight:409.7011-Oxo Etiocholanolone
CAS:<p>Applications A metabolite of Etiocholanolone.<br>References Eriksson, H., et al.: Eur. J. Biochem., 15, 132 (1970), Cook, D., et al.: Endocrinology, 93, 1019 (1973),<br></p>Formula:C19H28O3Color and Shape:White To Off-WhiteMolecular weight:304.423-O-Methyl Estrone
CAS:Controlled ProductFormula:C19H24O2Color and Shape:White To Dark BrownMolecular weight:284.3917-epi-Norethindrone
CAS:Controlled Product<p>Impurity Norethindrone EP Impurity G<br>Applications Norethindrone (N676000) epimer. Norethindrone and acetate is used in combination with estrogen as contraceptive (oral). Norethindrone EP Impurity G.<br>References Angel, P., et al.: Biochim. Biophys. Acta., 1072, 129 (1991), Chenu, C., et al.: J. Cell Biol., 127, 1149 (1994), Schmidt, M., et al.: J. Endocrinol., 158, 401 (1998),<br></p>Formula:C20H26O2Color and Shape:Off White SolidMolecular weight:298.4214,15-Dehydro Budesonide
CAS:Controlled Product<p>Impurity Budesonide EP Impurity E<br>Applications 14,15-Dehydro Budesonide (Budesonide EP Impurity E) is a Budesonide (B689490) impurity.<br>References Aherne, G., et al.: J. Steroid Biochem., 17, 559 (1982), Assi, K., et al.: J. Pharm. Biomed. Anal., 41, 325 (2006),<br></p>Formula:C25H32O6Color and Shape:WhiteMolecular weight:428.51820(S)-Hydroxy Prednisolone
CAS:Controlled Product<p>Impurity Prednisolone EP Impurity G<br>Applications 20(S)-Hydroxy Prednisolone (Prednisolone EP Impurity G) is a Prednisolone (P703740) metabolite.<br>References Kim, H., et al.: J. Med. Chem., 30, 2239 (1987), Addison, R., et al.: J. Steroid Biochem., Mol. Biol., 39, 83 (1991),<br></p>Formula:C21H30O5Color and Shape:NeatMolecular weight:362.46Cholesterol
CAS:<p>Applications Cholesterol is a major component of all biological membranes; ~25% of total brain lipid is Cholesterol. Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones. This compound is a contaminant of emerging concern (CECs).<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Formula:C27H46OColor and Shape:WhiteMolecular weight:386.6511-β,16-α,17-α,21-Tetrahydroxypregna-1,4-diene-3,20-dione
Formula:C21H28O6Color and Shape:NeatMolecular weight:376.44a-Acetyl Digoxin
CAS:Controlled Product<p>Applications Digoxin derivative, a cardiotonic glycosides steroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yoshida, F., et al.: J. Med. Chem., 43, 2575 ( 2000), Turner, J., et al.: Pharm. Res., 21, 68 (2004), Wang, J., et al.: Anal. Chim. Acta, 601, 156 (2007),<br></p>Formula:C43H66O15Color and Shape:NeatMolecular weight:822.985-ANDROSTEN-3,17-DIONE
CAS:Controlled Product<p>Applications 5-Androsten-3,17-dione has been used in the synthetic preparation of androstenediones for treatment of hormone-related disorders.<br>References Davies, H., et al.: U.S. (2011), WO 2011127232 A2<br></p>Formula:C19H26O2Purity:>90%Color and Shape:NeatMolecular weight:286.41Dihydro Dutasteride
CAS:<p>Applications Dihydro Dutasteride is an impurity arose during the process development of Dutasteride (D735000).<br>References Solomons, W., et al.: J. Pharma. Sci., 63, 19 (1974), Rasmusson, G., et al.: J. Med. Chem., 29, 2298 (1986),<br></p>Formula:C27H32F6N2O2Color and Shape:NeatMolecular weight:530.5516a,17-[(1RS)-Butylidenebis(oxy)]-11b-hydroxy-17-(hydroxymethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Mixture of Diastereomers)
CAS:Controlled Product<p>Impurity Budesonide EP Impurity C, Budesonide Impurity C,<br>Applications 16α,17-[(1RS)-butylidenebis(oxy)]-11β-hydroxy-17-(hydroxymethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Budesonide EP Impurity C) is an impurity of Budesonide (B689490), an antiinflammatory agent.<br>References Ferraboschi, P. et al.: J. Pharm. Biomed. Anal., 47, 636 (2008);<br></p>Formula:C25H34O6Color and Shape:WhiteMolecular weight:430.53Estrone 3-O-Sulfamate
CAS:Controlled Product<p>Applications A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM.<br>References Woo, L.W., et al.: J. Med. Chem., 41, 1068 (1998)<br></p>Formula:C18H23NO4SColor and Shape:NeatMolecular weight:349.44Didemethyl Mifepristone
CAS:Controlled Product<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Formula:C27H31NO2Color and Shape:NeatMolecular weight:401.54(6a,11b)-17,21-Bis(acetyloxy)-6,9-difluoro-11-hydroxy-pregna-1,4-diene-3,20-dione
CAS:Controlled ProductFormula:C25H30F2O7Color and Shape:NeatMolecular weight:480.53α,5β-Tetrahydro Norgestrel
CAS:Controlled Product<p>Applications The major metabolite of the progestational agent Norgestrel (N689500).<br>References DeJongh, D.C. et al.: Steroids, 11, 649 (1968); Uniyal, J.P. et al.: Acta Endocrinol., 84, 155 (1977); Sisenwine, S.F. et al.: Drug Metab. Disp., 7, 1 (1979);<br></p>Formula:C21H32O2Color and Shape:NeatMolecular weight:316.487β-Spironolactone
CAS:Controlled Product<p>Impurity Spironolactone EP Impurity E<br>Applications 7β-Spironolactone (Spironolactone EP Impurity E) is the 7β-isomer of Spironolactone (S683000). It binds effectively to human plasma proteins.<br>References Chien, Y.W. et al.: J. Pharmac. Sci., 65, 1337 (1976);<br></p>Formula:C24H32O4SColor and Shape:NeatMolecular weight:416.57
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