Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4949 products of "Steroids and Derivatives"
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Atorvastatin epoxy tetrahydrofuran impurity
CAS:<p>Atorvastatin epoxy tetrahydrofuran impurity is a byproduct of the synthesis process. It is a white crystalline powder that is soluble in organic solvents and sparingly soluble in water. Atorvastatin epoxy tetrahydrofuran impurity has been shown to be an impurity of atorvastatin. It is not known to have any biological activity, but it may pose a health risk if present in large quantities.</p>Formula:C26H24FNO5Purity:Min. 95%Color and Shape:PowderMolecular weight:449.47 g/mol(5α)-17-(3-Pyridinyl)androst-16-en-3-one
CAS:Controlled Product<p>(5α)-17-(3-Pyridinyl)androst-16-en-3-one is a natural metabolite of testosterone that is produced in the liver. It has been identified as an impurity in API, which can be found in drugs used for the treatment of high blood pressure and prostate cancer. (5α)-17-(3-Pyridinyl)androst-16-en-3-one is not active as a drug itself, but it can be used as a standard to study the metabolism of testosterone and other steroids.</p>Formula:C24H31NOPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:349.51 g/molAtorvastatin epoxy pyrrolooxazin tricyclic impurity
<p>Atorvastatin is a drug product that is metabolized to atorvastatin epoxy pyrrolooxazin tricyclic impurity. Due to the presence of this impurity, the purity of the drug product is not 100%. Atorvastatin epoxy pyrrolooxazin tricyclic impurity is a natural metabolite with CAS number 516-80-1. It has been shown to have effects on metabolism and may be involved in the development of atherosclerosis. Metabolism studies have been conducted on animals, but not humans.</p>Formula:C33H32FN2NaO6Purity:Min. 95%Molecular weight:594.61 g/molAtorvastatin lactone
CAS:<p>Atorvastatin lactone is a prodrug for atorvastatin. It is an inhibitor of the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis and reduces LDL cholesterol levels. Atorvastatin lactone is absorbed from the gut into the bloodstream and then converted to atorvastatin, which has a higher potency than atorvastatin lactone. This conversion occurs in the liver by cytochrome P450 enzymes, including cytochrome CYP3A4. The pharmacokinetics of atorvastatin lactone are influenced by drugs that inhibit these enzymes. Atorvastatin and its metabolites are excreted in human serum as glucuronide or sulfate conjugates.</p>Formula:C33H33FN2O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:540.62 g/molCalcipotriol EP Impurity H
<p>Calcipotriol EP Impurity H is an impurity found in calcipotriol EP. It is a metabolite of calcipotriol EP, which is the active ingredient in Dovonex. Calcipotriol EP Impurity H can be detected by HPLC with a retention time of 11.5 minutes and its purity can be determined by UV spectroscopy at 254 nm with a purity of >98%. Calcipotriol EP Impurity H can also be synthesized from natural or synthetic sources.</p>Formula:C54H78O5Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:807.19 g/molAtorvastatin EP Impurity D
CAS:<p>Soluble in Chloroform & in Methanol Confirmed<br>Insoluble in Water</p>Purity:95.0% MinColor and Shape:White or Off-White Crystalline Solid, Light SensitiveMolecular weight:431,46β-Epoxyabiraterone acetate
CAS:<p>Beta-Epoxyabiraterone acetate is a synthetic and natural metabolite of abiraterone that is used as an API impurity in the synthesis of abiraterone acetate. The drug product is a niche compound with CAS No. 52464-96-6. The Metabolite is an impurity found in the synthesis of beta-epoxyabiraterone acetate. Drug development research and development, analytical methods, and pharmacopoeia are all involved in the production of this compound.</p>Formula:C26H33NO3Purity:Min. 90 Area-%Color and Shape:White Off-White PowderMolecular weight:407.55 g/mol(3R,5S)-Atorvastatin sodium salt
CAS:<p>(3R,5S)-Atorvastatin sodium salt is a synthetic compound that is used in the treatment of high cholesterol. It belongs to the class of statins, which are used for lowering blood cholesterol levels. The drug product contains at least 99% by weight of (3R,5S)-atorvastatin sodium salt. This product also has an analytical purity greater than 98%. It is metabolized via oxidation and hydroxylation to form metabolites that exhibit pharmacological activity similar to the parent molecule. (3R,5S)-Atorvastatin sodium salt is a natural product that can be found in plants such as yew trees. This drug has been shown to have niche applications in drug development and research and development.</p>Formula:C33H34FN2NaO5Purity:Min. 95%Color and Shape:PowderMolecular weight:580.62 g/molTravoprost
CAS:<p>Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.</p>Formula:C26H35F3O6Purity:97.39% - 99.58%Color and Shape:Colorless OilMolecular weight:500.55Atorvastatin
CAS:<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>Formula:C33H35FN2O5Purity:99.37% - 99.69%Color and Shape:SolidMolecular weight:558.64Bexarotene
CAS:<p>Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).</p>Formula:C24H28O2Purity:99% - 99.65%Color and Shape:White SolidMolecular weight:348.48(R)-4-((5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
CAS:Purity:95%Molecular weight:392.58(3aR,4R,5R,6aS)-Hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-2-oxo-2H-cyclopenta[b]furan-5-yl Ester [1,1'-Biphenyl]-4-carboxylic Acid
CAS:<p>Applications Latanoprost Enol is an impurity of Latanoprost (L177280), a prostaglandin analogue used to treat glaucoma and other degenerative diseases of the eye.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993);<br></p>Formula:C31H30O5Color and Shape:NeatMolecular weight:482.5721-Carboxy Dexamethasone
CAS:<p>Applications 21-Carboxy Dexamethasone is a useful research chemical.<br>References Shepard, Allan R., ACS Chem. Biol., 3, 549-558(2013);<br></p>Formula:C22H27FO6Color and Shape:White To Off-WhiteMolecular weight:406.44Estriol 16a,17b-Diacetate
CAS:Controlled Product<p>Applications Estriol 16α,17β-Diacetate is a diacetate derivative of Estriol (E888960); an estrogenic metabolite considerably less potent than the hormone Estradiol (E888000).<br>References Marrian, et al.: Biochem. J., 23,1090 (1929); Huffman, et al.: J. Biol. Chem., 169, 167 (1947)<br></p>Formula:C22H28O5Color and Shape:NeatMolecular weight:372.45Ciclesonide-d11 (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.This compound is a mixture of diastereomers at the cyclohexyl acetal.<br>References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formula:C32D11H33O7Color and Shape:NeatMolecular weight:551.763-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic Acid Methyl Ester
CAS:Controlled Product<p>Impurity Finasteride EP Impurity B<br>Applications 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid Methyl Ester (Finasteride EP Impurity B) is an impurity of Finasteride (F342000) and Dutasteride (D735000). An intermediate in the synthesis of Finasteride and Dutasteride, 5α-reductase inhibitors used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders. Finasteride impurity.<br>References Bakshi., et al.: J. Med. Chem., 38, 3189 (1995),<br></p>Formula:C20H29NO3Color and Shape:White To Off-WhiteMolecular weight:331.456,7-Dihydrocanrenone
CAS:Controlled ProductFormula:C22H30O3Color and Shape:NeatMolecular weight:342.47(16α)-16-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregna-1,4-diene-3,11-dione
CAS:Controlled ProductFormula:C24H30O6Color and Shape:NeatMolecular weight:414.49Estradiol 3-Valerate
CAS:Controlled Product<p>Applications Estradiols ester used in polymeric matrix for transdermal treatment of osteoporosis.<br>References Tripathi, V.N., et al.: Can. J. Animal Sci., 48, 449 (1968),<br></p>Formula:C23H32O3Color and Shape:NeatMolecular weight:356.51(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate
CAS:Controlled Product<p>Applications (3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl [1,1'-biphenyl]-4-carboxylate is an intermediate in the synthesis of Prostaglandin E2 (P838610), the most common and biologically potent of mammalian prostaglandins.<br>References Radeuchel, B., et al.: Tetrahedron. Lett., 633, 9 (1975);<br></p>Formula:C21H18O5Color and Shape:NeatMolecular weight:350.364616-Methyl-17,20:20,21-bis[methylenebis(oxy)]-pregn-4-ene-3,11-dione
CAS:Controlled ProductFormula:C24H32O6Color and Shape:NeatMolecular weight:416.51rac 7-Methoxy Lasofoxifene
CAS:Controlled Product<p>Applications Lasofoxifene intermediate.<br>References Rosati, R., et al.: J. Med. Chem., 41, 2928 (1998),<br></p>Formula:C29H33NO2Color and Shape:NeatMolecular weight:427.58(4S,cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
CAS:Controlled Product<p>Applications An impurity of Atorvastatin.<br>References Graul, A., et al.: Drugs Fut. 22, 956 (1997),<br></p>Formula:C14H27NO4Color and Shape:NeatMolecular weight:273.3711β,16α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione-d3
Controlled Product<p>Applications A labelled metabolite of Budesonide (B689490), an antiinflammatory agent.<br>References Cserhati, T., et al.: J. Pharm. Biomed. Anal., 22, 25 (2000), Dilger, K., et al.: J. Clin. Pharmacol., 47, 1532 (2007), Buchwald, P., et al.: Steroids, 73, 193 (2008),<br></p>Formula:C21H25D3O6Color and Shape:NeatMolecular weight:379.466a-Hydroxy Levonorgestrel
CAS:<p>Impurity Levonorgestrel EP Impurity G<br>Applications 6α-Hydroxy Levonorgestrel (Levonorgestrel EP Impurity G) is a hydroxylated impurity of Norgestrel (N689500).<br>References Lin, Y., et al.: Biochim. Biophys. Acta, 218, 526 (1970), Smith, K., et al.: J. Steroid Biochem., 32, 445 (1989), Hu, S., et al.: Steroids, 60, 337 (1995),<br></p>Formula:C21H28O3Color and Shape:White SolidMolecular weight:328.44Exemestane-13C,D3
CAS:Controlled Product<p>Applications Exemestane-13C,D3 is the labeled analogue of Exemestane (E957000), an antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Formula:C1913CH21D3O2Color and Shape:NeatMolecular weight:300.41(5E)-Calcipotriene
CAS:Controlled Product<p>Impurity Calcipotriol EP Impurity C<br>Stability Temperature Sensitive<br>Applications The trans-isomeric impurity of Calcipotriene (C144200) and a vitamin D3 analogue with antitumor effects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wietrzyk, J. et al.: Anti-Cancer Drugs, 18, 447 (2007); Wietrzyk, J. et al.: Anticancer Res., 27, 3387 (2007); Filip, B. et al.: J. Ster. Biochem. Mol. Biol., 121, 399 (2010);<br></p>Formula:C27H40O3Color and Shape:NeatMolecular weight:412.6013-Ethyl-3-ethynyl-18,19-dinor-17α-pregna-3,5-dien-20-yn-17-ol(Levo Norgestrel Impurity)
CAS:Controlled Product<p>Impurity Levonorgestrel EP Impurity C<br>Applications 13-Ethyl-3-ethynyl-18,19-dinor-17α-pregna-3,5-dien-20-yn-17-ol (Levonorgestrel EP Impurity C) is an impurity of Levonorgestrel.<br></p>Formula:C23H28OColor and Shape:NeatMolecular weight:320.47Vitamin D3 b-D-Glucuronide, >90%
CAS:Controlled Product<p>Stability Temperature and Light Sensitive<br>Applications A metabolite of Vitamin D3.<br>References Bell, P.A., et al.: Biochem. J., et al.: 115, 663 (1969), Kumar, R.S., et al.: J. Clin. Invest., 65, 277 (1980), Shimada, K., et al.: Biol. Pharm. Bull., 19, 491 (1996),<br></p>Formula:C33H52O7Purity:>90%Color and Shape:NeatMolecular weight:560.76∆9,11-Dehydro-17α-cyanomethyl Estradiol
CAS:Controlled Product<p>Applications ∆9,11-Dehydro-17α-cyanomethyl estradiol is a metabolite of progestin dienogest (D441870), and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.<br>References Oettel, M., et al.: Pharmazie, 41, 627 (1993); Kiley, J. & Shulman, L.: Int. J. Womens Health, 3, 281 (2011);<br></p>Formula:C20H23NO2Color and Shape:NeatMolecular weight:309.40Dexamethasone acetate monohydrate
CAS:<p>Dexamethasone acetate treats rheumatic issues, skin conditions, asthma, allergies, COPD, brain swelling, croup, TB adjunct.</p>Formula:C24H33FO7Color and Shape:SolidMolecular weight:452.523-(N-Phenyl-N-methyl)aminoacrolein
CAS:<p>3-(N-Phenyl-N-methyl)aminoacrolein is a hydrophobic compound that has been shown to reversibly bind to serum albumin. This binding leads to a decrease in the lipid content of lipoproteins and a decrease in the rate of their metabolism. These effects are mediated by hydrophobic interactions with the hydrophobic regions of serum albumin. 3-(N-Phenyl-N-methyl)aminoacrolein also interacts with human serum albumin, which is involved in lipid transport and metabolism, and can be used as a contrast agent for X-ray diffraction studies.</p>Formula:C10H11NOPurity:Min. 97 Area-%Color and Shape:PowderMolecular weight:161.2 g/mol(4R)-4-[(1S,2S,5R,7R,10R,11S,14R,15R,16S)-5,16-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
CAS:Formula:C24H40O4Purity:98%Color and Shape:SolidMolecular weight:392.58Desogestrel
CAS:Controlled Product<p>Applications A progestogen with low androgenic potency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Viinikka, L., et al.: Eur. J. Clin. Pharmacol., 15, 349 (1979), Bergink, E.W., et al.: J. Steroid Biochem., 14, 175 (1981)<br></p>Formula:C22H30OColor and Shape:White To Off-WhiteMolecular weight:310.47(11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione(Deflazacort Impurity)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications (11β,16β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, is an impurity of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus.<br>References Nathansohn, G., et al.: J. Med. Chem., 10,799 (1967), Schiatti, P., et al.: Arzneim. Forsch., 30, 1543 (1980), Cavall-Perin, P., et al.: Eur. J. Clin. Pharmacol., 26, 357 (1984), Imbimbo, B., et al.: Adv. Exp. Med. Biol., 171, 241 (1984),<br></p>Formula:C27H33NO7Color and Shape:NeatMolecular weight:483.556α-Hydroxy-21-desacetyl Deflazacort
CAS:Controlled Product<p>Applications The minor metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Formula:C23H29NO6Color and Shape:NeatMolecular weight:415.48Desisobutyryl Ciclesonide
CAS:Controlled Product<p>Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma.<br>References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).<br></p>Formula:C28H38O6Color and Shape:White To Off-WhiteMolecular weight:470.60(5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one
CAS:Controlled Product<p>Applications (5α)-17,17-Dimethyl-18-nor-2-oxaandrost-13-en-3-one is metabolite and impurity of the anabolic steroid Oxandrolone (O845050).<br>References Fragkaki, A.G. et al.: J. Steroid Biochem. Mol. Biol., 115, 44 (2009); Bi, H. et al.: J. Steroid Biochem. Mol. Biol., 42, 533 (1992);<br></p>Formula:C19H28O2Color and Shape:White To Off-WhiteMolecular weight:288.4217β-Hydroxy Exemestane-d3 17-O-β-D-Glucuronide
CAS:Controlled Product<p>Applications 17β-Hydroxy Exemestane 17-O-β-D-Glucuronide is the glucuronidated conjugate of the hydroxy metabolite of Exemestane (E957000).<br>References Sun, D. et al.: Pharmacogen. Genom., 20, 575 (2010);<br></p>Formula:C26H31D3O8Color and Shape:NeatMolecular weight:477.56Ciclesonide-d7
CAS:Controlled Product<p>Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.<br>References ukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).<br></p>Formula:C32H37D7O7Color and Shape:NeatMolecular weight:547.737α-Acetylthio-17α-ethoxymethyl Testosterone
CAS:Controlled ProductFormula:C24H36O4SColor and Shape:NeatMolecular weight:420.611-Dehydro Aldosterone
CAS:Controlled ProductFormula:C21H26O5Color and Shape:NeatMolecular weight:358.43(9β,11β,16α)-9,11-Epoxy-21-hydroxy-16-methyl-pregna-1,4-diene-3,20-dione
CAS:Controlled Product<p>Applications Glucocorticoid.<br></p>Formula:C22H28O4Color and Shape:NeatMolecular weight:356.46
![(3aR,4R,5R,6aS)-Hexahydro-4-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]-2-oxo-2H-cyclopenta[b]furan…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FH294040.webp&w=3840&q=75)
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