Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4967 products of "Steroids and Derivatives"
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6-Bromo-betamethasone 17,21-Dipropionate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Formula:C28H36BrFO7Color and Shape:NeatMolecular weight:583.482-Hydroxymethylene Ethisterone
CAS:Controlled Product<p>Applications A derivative of Danazol (D145000).<br>References Manson, A.J., et al.: J. Med. Chem., 6, 1 (1963), Jordan, V.C., et al.: Endocrinology, 124, 1717 (1989),<br></p>Formula:C22H28O3Color and Shape:NeatMolecular weight:340.46(6a,11b,16a)-21-(Acetyloxy)-6,9-difluoro-11,16,17-trihydroxypregna-1,4-diene-3,20-dione
CAS:Controlled Product<p>Applications (6α,11β,16α)-21-(Acetyloxy)-6,9-difluoro-11,16,17-trihydroxypregna-1,4-diene-3,20-dione is an impurity of Fluocinolone Acetonide, Glucocorticoid; anti-inflammatory.<br>References Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),<br></p>Formula:C23H28F2O7Color and Shape:NeatMolecular weight:454.466α-Methyl Hydrocortisone
CAS:<p>Applications A metabolite of Cortisone (C696500).<br>References Mashkovskii, M., et al.: Med. Agents, 2, 34 (2002),<br></p>Formula:C22H32O5Color and Shape:Off-White To BeigeMolecular weight:376.496b-Hydroxy Norethindrone
CAS:Controlled Product<p>Impurity Norethindrone EP Impurity H<br>Applications 6β-Hydroxynorethindrone (Norethindrone EP Impurity H) is the 6β-hydroxy analogue of Norethindrone (N676000). 6β-Hydroxynorethindrone is also a metabolite of the progestagen hormone, Lynestrenol.<br>References Choudhary, M.I. et al.: Nat. Prod. Res., 24, 1 (2010); Bagocsi, B. et al.: J. Plan. Chrom. Mod. TLC, 16, 359 (2003);<br></p>Formula:C20H26O3Color and Shape:NeatMolecular weight:314.42(3a)-Allopregnanolone Sulfate Pyridinium Salt
CAS:Controlled Product<p>Applications (3α)-Allopregnanolone Sulfate is the sulfate conjugate of (3α)-Allopregnanolone (A547100), a metabolite of progesterone and potent positive modulator of GABAA receptors.<br>References El-Etr, M. et al.: Brain Res., 790, 334 (1998); Hauser, C.A.E. et al.: Eur. J. Pharmacol. Mol. Pharmacol. Sec., 289, 249 (1995);<br></p>Formula:C26H39NO5SColor and Shape:White To Off-WhiteMolecular weight:477.666a,9a-Difluoroprednisolone 21-Acetate
CAS:Controlled Product<p>Applications 6α,9α-Difluoroprednisolone 21-Acetate, is an impurity of Difluprednate (D445925), which is shown to have antiinflammatory activity.<br>References Toscano L., et al.: J. Med. chem., 20, 213 (1977);<br></p>Formula:C23H28F2O6Color and Shape:White To Off-WhiteMolecular weight:438.46(3b)-Allopregnanolone Sulfate Sodium Salt
CAS:Controlled Product<p>Applications (3β)-Allopregnanolone Sulfate is the sulfate conjugate of (3β)-Allopregnanolone, a metabolite of progesterone and a potent inhibitory modulator of GABAA receptors.<br>References Li, P. et al.: Mol. Pharmacol., 77, 539 (2010); El-Etr, M. et al.: Brain Res., 790, 334 (1998); Park-Chung, M. et al.: Brain Res., 830, 72 (1999);<br></p>Formula:C21H33NaO5SColor and Shape:NeatMolecular weight:420.54Desmethyl Cerivastatin, Sodium Salt
CAS:Controlled ProductFormula:C25H31FNO5·NaColor and Shape:NeatMolecular weight:467.516-Keto 17b-Estradiol
CAS:Controlled ProductFormula:C18H22O3Color and Shape:Off-WhiteMolecular weight:286.37Δ5(10),6,8(9)-D-(-)-Norgestrel
CAS:Controlled ProductFormula:C21H24O2Color and Shape:NeatMolecular weight:308.414Testosterone-d3 Propionate
CAS:Controlled Product<p>Applications Isotope labelled Testosterone Propionate (T155045), Anabolic steroid. Androgen.Controlled substance.<br>References Glass, A., et al.: J. Clin. Endocrinol. Metab., 45, 1211 (1977), Behre, H., et al.: Eur. J. Endocrinol., 140, 414 (1999), Nieschlag, E., et al.: Steroids, 68, 965 (2003), Wang, C., et al.: J. Clin. Endocrinol. Metab., 91, 460 (2006),<br></p>Formula:C222H3H29O3Color and Shape:NeatMolecular weight:347.51Dexamethasone-d5 Acid Ethyl Ester
Controlled Product<p>Applications Isotope Labelled Dexamethasone Acid Ethyl Ester is a derivative of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formula:C23D5H26FO5Color and Shape:NeatMolecular weight:411.526-[(1E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-5,6-dihydro-4-hydroxy-2H-pyran-2-one
CAS:<p>Impurity Fluvastatin EP Impurity E<br>Applications 6-[(1E)-2-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]ethenyl]-5,6-dihydro-4-hydroxy-2H-pyran-2-one (Fluvastatin EP Impurity E) is an impurity of Fluvastatin (F601250), a synthetic HMG-CoA reductase inhibitor. Antilipemic.<br>References Yuan, J., et al.: Atherosclerosis, 87, 147 (1991), Tse, F.L.S., et al.: J. Clin. Pharmacol., 32, 630 (1992), Dain, J.G., et al.: Drug Metab. Disposit., 21, 567 (1993)<br></p>Formula:C24H22FNO3Color and Shape:NeatMolecular weight:391.43Dexamethasone 21-Formate
CAS:Controlled Product<p>Applications Dexamethasone 21-Formate is a metabolite of Dexamethasone.<br>References Minagawa, K., et al.: Steroids, 47, 175 (1986), Murray, G., et al.: Br. J. Clin. Pharmacol., 25, 465 (1988), Ravichandran, K., et al.: Science, 1993, 261, 731 (1993),<br></p>Formula:C23H29FO6Color and Shape:NeatMolecular weight:420.474-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid
CAS:Controlled Product<p>Applications 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid is used in the preparation of pentamethylnaphthylmethylbenzoates as a selective retinoid X receptor ligands that induce apoptosis in leukemia cells.<br>References Boehm, M.F., et al.: J. Med. Chem., 38, 3146-55 (1995); Furmie, J.K., et al.: ChemMedChem, 7, 1551-66 (2012)<br></p>Formula:C23H26O3Color and Shape:NeatMolecular weight:350.45Pregnenolone-d4
CAS:Controlled Product<p>Applications Pregnenolone-d4, is the labeled analogue of the Pregnenolone (P712200), which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),<br></p>Formula:C212H4H28O2Color and Shape:Off-WhiteMolecular weight:320.50Etonogestrel Sulfate Sodium Salt
Controlled Product<p>Applications A metabolite of Etonogestrel.<br></p>Formula:C22H27NaO5SColor and Shape:NeatMolecular weight:426.50220b-Dihydroprogesterone
CAS:Controlled Product<p>Impurity Progesterone EP Impurity C<br>Applications 20β-Dihydroprogesterone (Progesterone EP Impurity C) is an impurity of Progesterone (P755900), a steroid hormone secreted by the corpus luteum. Progesterone have various significant physiological roles, such as inducing the maturation and secretory activities of the uterine endothelium and the suppression of ovulation. Progesterone is also implicated in the etiology of breast cancer.<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formula:C21H32O2Color and Shape:White To Off-WhiteMolecular weight:316.486α-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione
CAS:Controlled Product<p>Applications 6α-Spiro[androsta-1,4-diene-6,2'-oxiran]-3,17-dione is a metabolite of exemestane (E957000). Exemestane is an antineoplastic (hormonal).<br>References Giudici, D., et al.: J. Steroid Biochem., 30, 391 (1988), Evans, T.R.J., et al.: Cancer Res., 52, 5933 (1992), Zilembo, N., et al.: Brit. J. Cancer, 72, 1007 (1995)<br></p>Formula:C20H24O3Color and Shape:White To Off-WhiteMolecular weight:312.403
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