Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4968 products of "Steroids and Derivatives"
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6β-Muethyl Prednisolone 21-Acetate (>90%)
CAS:Controlled Product<p>Applications 6β-Μethyl Prednisolone 21-Acetate is the 6-methyl isomer of 6α-Methyl Prednisolone 21-Acetate (M326030).<br>References Sugihara, N., et al: Am. J. Cardiol., 69, 1475 (1992), Bracken, M.B., et al.: J. Neurosurg., 89, 699 (1998), Dammers, J.W.H.H., et al.: Brit. Med. J., 319, 884 (1999).<br></p>Formula:C24H32O6Purity:>90%Color and Shape:NeatMolecular weight:416.514-Hydroxy Atorvastatin Hemicalcium Salt
CAS:<p>Applications 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);<br></p>Formula:C66H68CaF2N4O12Purity:>90%Color and Shape:NeatMolecular weight:1187.3417-Epiestriol-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Estradiol (E888000).<br>References Marrian, B., et al.: Biochem. J., 59, 136 (1955), Dietel, M., et al.: Cancer Res., 50, 6100 (1990), Schumacher, G., et al.: Clin. Cancer Res., 5, 493 (1999), Robert, J., et al.: J. Med. Chem., 46, 4805 (2003),<br></p>Formula:C18H19D5O3Color and Shape:NeatMolecular weight:293.41Pregna-4,9(11)-diene-3,20-dione (90%)
CAS:Controlled Product<p>Applications Pregna-4,9(11)-diene-3,20-dione is a Progesterone (P755900) impurity, a steroid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.<br>References Thomas, P. et al.: Endocrinol., 148, 705 (2007); Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formula:C21H28O2Purity:90%Color and Shape:NeatMolecular weight:312.455,6-Dehydro-17b-dutasteride
CAS:Controlled Product<p>Impurity Dutateride EP Impurity G<br>Applications 5,6-Dehydro-dutasteride (Dutateride EP Impurity G) is an impurity in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formula:C27H28F6N2O2Color and Shape:NeatMolecular weight:526.51Bisnorcholenaldehyde
CAS:Controlled Product<p>Applications Bisnorcholenaldehyde can be used to prepare 27-Nor-Δ4-dafachronic acid as a synthetic ligand of Caenorhabditis elegans DAF-12 receptor. It is also used to synthesize 3β,6α-dihydroxy-5α-cholan-23-one.<br>References Samaja, G., et al.: Bioorg. Med. Chem. Lett., 23, 2893 (2013); Nahar, L., et al.: Tetrahedron, 59, 8623 (2003)<br></p>Formula:C22H32O2Color and Shape:NeatMolecular weight:328.49Testosterone-d3 β-D-Glucuronide Monosodium Salt
CAS:Controlled Product<p>Applications Labelled Metabolite of Testosterone (T155000).<br>References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug<br></p>Formula:C25H32D3NaO8Color and Shape:Off-WhiteMolecular weight:489.55Prednisolone Tebutate
CAS:Controlled Product<p>Applications Prednisolone Tebutate is an anaesthetic corticosteroid.<br>References Lewis, A. et al.: Agents and Actions, 10, 258 (1980); Myers, S. et al.: Arthris. Rheum., 28, 1275 (1985);<br></p>Formula:C27H38O6Color and Shape:NeatMolecular weight:458.59Betamethasone 17-Propionate-d5
CAS:Controlled ProductFormula:C25H28D5FO6Color and Shape:NeatMolecular weight:453.56D-Digitoxose
CAS:Controlled Product<p>Applications D-Digitoxose is a derivative of D-ribo-Hexonic acid that is metabolized in the liver. It inhibits glucose-stimulated insulin release.<br>References Domschke, W. et al.: Naun.-Schmied. Arch. Pharmacol., 265, 149 (1969); Brown, D.F. et al.: Experientia, 39, 979 (1983); Hussain, M. et al.: Biochem. Biophys. Res. Comm., 129, 358 (1985);<br></p>Formula:C6H12O4Purity:>85%Color and Shape:White SolidMolecular weight:148.16Digoxigenin Bisdigitoxoside
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Formula:C35H54O11Color and Shape:NeatMolecular weight:650.8017-Desacetyl Norgestimate-d6 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Norgestimate.<br>References Phillips, A., et al.: Steroids, 55, 373 (1990)<br></p>Formula:C21D6H23NO2Color and Shape:NeatMolecular weight:333.5Desonide 21-Acetate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Desonide 21-Acetate is a reactant in the synthesis of 7α-halogenocorticosteroids with anti-inflammatory activity.<br>References De, K., et. al.: J. Indian Chem. Soc., 79, 513 (2002)<br></p>Formula:C26H34O7Color and Shape:NeatMolecular weight:458.54trans-Latanoprost
CAS:<p>Impurity Latanoprost USP Related Compound A<br>Stability Temperature Sensitive<br>Applications Prostaglandin analog; prodrug of active acid metabolite. It is a synthetic derivative of the natural prostaglandin PGF2α, used as an anti-glaucoma agent that is effective in various types of glaucoma and ocular hypertension. Latanoprost USP Related Compound A.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993), Toris, C., et al.: Ophthalmology, 100, 1297 (1993), Holmstrom, S., et al.: Curr. Med. Res. Op., 21, 1875 (2005),<br></p>Formula:C26H40O5Color and Shape:ColourlessMolecular weight:432.5921-Dehydrocorticosterone (mixture of the aldehyde and the hydrated form)
CAS:Formula:C21H28O4Color and Shape:NeatMolecular weight:344.44(17β)-N-(1,1-Dimethylethyl)-3-oxoandrost-4-ene-17-carboxamide
CAS:Controlled ProductFormula:C24H37NO2Color and Shape:Off-WhiteMolecular weight:371.56Promestriene
CAS:Controlled Product<p>Applications A synthetic diethyl-ether of Estradiol with no distal hormonal effects, in patients undergoing surgical correction for stress urinary incontinence (SUI).<br>References Kelleher, C., et al.: Br. J. Obstet. Gynaecol., 104, 1374 (1997), Deffieux, X., et al.: J. Gynecol. Obstet. Biol. Reprod., 35, 678 (2006),<br></p>Formula:C22H32O2Color and Shape:NeatMolecular weight:328.492-Hydroxy-17β-estradiol
CAS:<p>Applications A metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>Formula:C18H24O3Color and Shape:Light Yellow To Dark YellowMolecular weight:288.38
