Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4973 products of "Steroids and Derivatives"
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15-Keto Travoprost
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications An impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600) used as an ocularly applied intraocular pressure reducing agent.<br></p>Formula:C26H33F3O6Color and Shape:NeatMolecular weight:498.53(22R)-Budesonide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Budesonide (B689490) epimer R. Budesonide 22R epimer is more active than 22S epimer. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Formula:C25H34O6Color and Shape:NeatMolecular weight:430.53Pregnenolone Acetate
CAS:Controlled Product<p>Applications Pregnenolone (P712200) derivative, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens<br>References Bjondahl, K., et al.: Med. Biol., 54, 454 (1976), Geick, A., et al.: J. Biol. Chem., 276, 14581 (2001), Johnson, D., et al.: Toxicol. Sci., 66, 16 (2002), Abe, C., et al.: Lipids, 42, 637 (2007),<br></p>Formula:C23H34O3Color and Shape:NeatMolecular weight:358.51Prednisolone 21-Methanesulfonate
CAS:Controlled ProductFormula:C22H30O7SColor and Shape:NeatMolecular weight:438.534(17α)-13-Ethyl-3-methoxy-18,19-dinorpregna-3,5-dien-20-yn-17-ol
CAS:Controlled Product<p>Applications Norgestrel (N689500) impurity.<br>References Gorog, S., et al.: J. Chromatogr., 400 177 (1987),<br></p>Formula:C22H30O2Color and Shape:NeatMolecular weight:326.4725-Hydroxy Vitamin D2
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of Vitamin D2 (V676040).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Barnes, P., et al.: J. Clin. Invest., 83, 1527 (1989), Holick, M., et al.: J. Cell Biochem., 88(2), 296 (2003), Maunsell, Z., et al.: Clin. Chem., 51, 1683 (2005),<br></p>Formula:C28H44O2Color and Shape:White To Light YellowMolecular weight:412.657,7’-Nonane-1,9-diylbis[estra-1,3,5(10)-triene-3,17β-diol](Mixture of Diastereomers)
Controlled Product<p>Applications Fulvestrant (F862500) impurity D.<br></p>Formula:C45H64O4Color and Shape:NeatMolecular weight:668.994-Hydroxy Atorvastatin Disodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Formula:C33H33FN2Na2O6Color and Shape:White To BrownMolecular weight:618.6011-Dehydrodexamethasone
CAS:Controlled ProductFormula:C22H27FO5Color and Shape:NeatMolecular weight:390.4452(15S)-Latanoprost
CAS:<p>Impurity Latanoprost USP Related Compound B<br>Applications An impurity of commercially prepared Latanoprost (L177280). Latanoprost USP Related Compound B.<br>References Resul, B., et al.: J. Med. Chem., 36, 2242 (1993),<br></p>Formula:C26H40O5Color and Shape:ColourlessMolecular weight:432.59Isoflupredone Acetate
CAS:Controlled Product<p>Applications An anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.<br>References Coffer, N.Y. et al.: Am. J. Vet. Res., 67, 1244 (2006); Seifi, H.A. et al.: J. Diary Sci., 90, 4181 (2007);<br></p>Formula:C23H29FO6Color and Shape:Off-WhiteMolecular weight:420.47δ7,9(11)-Dexamethasone
CAS:<p>Stability Hygroscopic<br>Applications Dexamethasone (D298800) process impurity.<br></p>Formula:C22H26O4Color and Shape:NeatMolecular weight:354.446α-Hydroxy Androstenedione
CAS:Controlled Product<p>Applications A metabolite of Androstenedione (A637550).<br>References Gazdar, A., et al.: Cancer Res., 50, 5488 (1990), Levesque, J., et al.: Steroids, 70, 305 (2005), Lootens, L., et al.: Drug Metab. Dispos., 37, 2367 (2009),<br></p>Formula:C19H26O3Color and Shape:NeatMolecular weight:302.41Fluorometholone
CAS:Controlled Product<p>Applications Fluorometholone is a glucocorticoid; anti-inflammatory.<br>References Kupferman, A., et al.: Arch. Ophthlmol., 640, 100 (1982), Tokunaga H., et al.: Chem. Pharm. Bull., 32, 4012 (1984),<br></p>Formula:C22H29FO4Color and Shape:White To Off-WhiteMolecular weight:376.46Estrone b-D-Glucuronide Sodium Salt (>97% by HPLC)
CAS:Controlled Product<p>Applications A metabolite of 17β -Estradiol (E888000).<br>References Cekan, S., et al.: J. Steroid Biochem., 27, 95 (1989), Martin, R., et al.: Clin. Chem., 46, 100 (2000), Blackwell, L., et al.: Steroids, 68, 465 (2003)<br></p>Formula:C24H29O8·NaPurity:>97% by HPLCColor and Shape:White To Light BrownMolecular weight:468.474-Hydroxy Atorvastatin Hemicalcium Salt
CAS:<p>Applications 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);<br></p>Formula:C66H68CaF2N4O12Purity:>90%Color and Shape:NeatMolecular weight:1187.345,6-Dehydro-17b-dutasteride
CAS:Controlled Product<p>Impurity Dutateride EP Impurity G<br>Applications 5,6-Dehydro-dutasteride (Dutateride EP Impurity G) is an impurity in the synthesis of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005),<br></p>Formula:C27H28F6N2O2Color and Shape:NeatMolecular weight:526.51
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