Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4982 products of "Steroids and Derivatives"
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(3R,5S)-Atorvastatin sodium salt
CAS:(3R,5S)-Atorvastatin sodium salt is a synthetic compound that is used in the treatment of high cholesterol. It belongs to the class of statins, which are used for lowering blood cholesterol levels. The drug product contains at least 99% by weight of (3R,5S)-atorvastatin sodium salt. This product also has an analytical purity greater than 98%. It is metabolized via oxidation and hydroxylation to form metabolites that exhibit pharmacological activity similar to the parent molecule. (3R,5S)-Atorvastatin sodium salt is a natural product that can be found in plants such as yew trees. This drug has been shown to have niche applications in drug development and research and development.Formula:C33H34FN2NaO5Purity:Min. 95%Color and Shape:PowderMolecular weight:580.62 g/mol(5α)-17-(3-Pyridinyl)androst-16-en-3-one
CAS:Controlled Product(5α)-17-(3-Pyridinyl)androst-16-en-3-one is a natural metabolite of testosterone that is produced in the liver. It has been identified as an impurity in API, which can be found in drugs used for the treatment of high blood pressure and prostate cancer. (5α)-17-(3-Pyridinyl)androst-16-en-3-one is not active as a drug itself, but it can be used as a standard to study the metabolism of testosterone and other steroids.Formula:C24H31NOPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:349.51 g/molDefluoro atorvastatin acetonide tert-butyl ester
CAS:Please enquire for more information about Defluoro atorvastatin acetonide tert-butyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C40H48N2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:636.82 g/molAtorvastatin EP Impurity D
CAS:Soluble in Chloroform & in Methanol Confirmed
Insoluble in WaterPurity:95.0% MinColor and Shape:White or Off-White Crystalline Solid, Light SensitiveMolecular weight:431,463-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic acid
CAS:3-Oxo-4-aza-5a-androst-1-ene-17b-carboxylic acid is a covalently bonded prodrug that is metabolized to its active form, finasteride, in the body. It has been shown to have physiological activities such as skin permeation and cell growth. 3-Oxo-4-aza-5a-androst-1-ene 17b carboxylic acid also has immunotherapy properties and can be conjugated with other compounds for use in cancer treatment.Formula:C19H27NO3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:317.42 g/molCalcipotriol EP Impurity G
Calcipotriol EP Impurity G is an impurity in calcipotriol, which is a drug product. Calcipotriol EP Impurity G has a CAS number of 126825-26-3 and is a natural metabolite of calcipotriol. It is also known as calcipotriol EP Impurity G or calcipotriol EPIG. It has been shown to be an analytical impurity in calcipotriol, and it has been detected by HPLC analysis. Calcipotriol EP Impurity G can be used for research and development, as well as for the production of pharmacopoeia standards.Formula:C54H78O5Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:807.19 g/molDefluoro atorvastatin calcium
CAS:Defluoro atorvastatin calcium is a bulk drug that has been approved to be used as an adjunct to diet to reduce elevated cholesterol levels in adults. Defluoro atorvastatin calcium is the desfluoro-enantiomer of atorvastatin, which is a statin that inhibits the enzyme HMG-CoA reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonic acid, which is an early step in the synthesis of cholesterol. The fluoro group on defluoro atorvastatin calcium is not expected to have any significant effect on its potency or metabolic pathways and any impurities are not expected to have any therapeutic effect.Formula:C66H70CaN4O10Purity:Min. 95%Color and Shape:White PowderMolecular weight:1,119.36 g/molAtorvastatin lactam sodium salt impurity
CAS:Atorvastatin is a drug used for the treatment of hypercholesterolemia and cardiovascular diseases. Atorvastatin lactam, which is an impurity formed during the synthesis of atorvastatin, has been shown to inhibit cholesterol biosynthesis in a rat model. The in vivo metabolism of atorvastatin lactam was studied by HPLC-MS/MS and was found to be identical to that of the parent molecule. This impurity may be useful as a research and development or custom synthesis product, or as an impurity standard for HPLC analysis.
Formula:C33H34FN2NaO6Purity:Min. 95%Color and Shape:White PowderMolecular weight:596.62 g/molAtorvastatin lactone
CAS:Atorvastatin lactone is a prodrug for atorvastatin. It is an inhibitor of the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis and reduces LDL cholesterol levels. Atorvastatin lactone is absorbed from the gut into the bloodstream and then converted to atorvastatin, which has a higher potency than atorvastatin lactone. This conversion occurs in the liver by cytochrome P450 enzymes, including cytochrome CYP3A4. The pharmacokinetics of atorvastatin lactone are influenced by drugs that inhibit these enzymes. Atorvastatin and its metabolites are excreted in human serum as glucuronide or sulfate conjugates.Formula:C33H33FN2O4Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:540.62 g/molCalcipotriol EP Impurity B
Calcipotriol EP Impurity B is a drug product that is an impurity in Calcipotriol EP. It is produced during the synthesis of calcipotriol and may be present in the natural product. It has been shown to have anti-inflammatory properties, and can be used as a research tool to study calcipotriol metabolism.Formula:C27H40O3Purity:Min. 95%Molecular weight:412.6 g/molFluticasone propionate EP Impurity F
CAS:Fluticasone Propionate EP Impurity F is an impurity of Fluticasone Propionate. Fluticasone Propionate is a synthetic glucocorticoid used in the treatment of asthma and other allergic disorders. Impurity F is a metabolite of Fluticasone Propionate and has been detected in human plasma at low levels (5% of total fluticasone propionate). The metabolism of Fluticasone Propionate to Impurity F has been studied in rat, mouse, dog and man. br>br> The following table summarizes the metabolic pathways that have been identified for this impurity: br>br> Metabolism studies indicate that Impurity F is mainly metabolized by CYP3A4 to form conjugates with glucuronic acid or sulfates. It may also be hydrolyzed to form 5α-flurostan-3β,17β-dFormula:C25H29F3O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:498.56 g/molDutasteride impurity F
CAS:Dutasteride impurity D is a natural impurity found in dutasteride and has been reported to be an analytical marker for dutasteride. It is also used as an impurity standard, HPLC standard, and custom synthesis for drug development. Metabolism studies have shown that the major route of elimination for Dutasteride impurity D is through glucuronidation with minor amounts being excreted in urine unchanged.
Formula:C27H31ClF6N2O2Purity:Min. 95 Area-%Molecular weight:564.99 g/molrac-3-Oxo atorvastatin sodium salt
CAS:Racemic 3-Oxo atorvastatin sodium salt (3OAS) is a drug product that has been tested in the laboratory and found to be suitable for further development. It is a natural substance that has not been chemically synthesized. Racemic 3-Oxo atorvastatin sodium salt is an impurity standard that can be used to establish the purity of API drugs. It can also be used as a metabolite in metabolism studies. Racemic 3-Oxo atorvastatin sodium salt is high purity and can be used for niche applications such as pharmacopoeia production.Formula:C33H32FN2NaO5Purity:Min. 95%Color and Shape:PowderMolecular weight:578.61 g/molO-Methyl atorvastatin calcium
CAS:O-Methyl atorvastatin calcium is a drug product that is an HPLC standard. It is a natural metabolite of atorvastatin, which is synthesized by cytochrome P450 3A4 in the liver. O-Methyl atorvastatin calcium has been shown to be an impurity in some batches of atorvastatin calcium. It has been observed to have pharmacological effects similar to those of atorvastatin. O-Methyl atorvastatin calcium has been used as a research and development (R&D) tool for studies on the metabolism of drugs, including its own synthesis and the study of the effect on other drugs such as amiodarone.Formula:CaC68H71F2N4O10Purity:Min. 95%Color and Shape:PowderMolecular weight:1,182.39 g/molVitamin A EP Impurity C
CAS:Soluble in Chloroform & in Methanol Confirmed
Insoluble in WatePurity:90% minColor and Shape:Off White or Beige SolidMolecular weight:312.45Atorvastatin epoxy tetrahydrofuran impurity
CAS:Atorvastatin epoxy tetrahydrofuran impurity is a byproduct of the synthesis process. It is a white crystalline powder that is soluble in organic solvents and sparingly soluble in water. Atorvastatin epoxy tetrahydrofuran impurity has been shown to be an impurity of atorvastatin. It is not known to have any biological activity, but it may pose a health risk if present in large quantities.Formula:C26H24FNO5Purity:Min. 95%Color and Shape:PowderMolecular weight:449.47 g/molCalcipotriol EP impurity E
Calcipotriol EP Impurity E is a synthetic impurity that is found in the calcipotriol EP API. Calcipotriol EP Impurity E is an impurity standard for HPLC and can be used in drug development, research and development, and pharmacopoeia. It has been shown to have no significant effect on the pharmacological activity of calcipotriol EP.
Formula:C27H42O3Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:414.62 g/mol
