Organic Phosphates and Phosphonates
Organic phosphates are compounds that contain a phosphate group (-PO₄) attached to a carbon atom within an organic structure, typically in combination with alcohols, acids, or amines. These compounds are used in API formulation to enhance the solubility, stability, and bioavailability of active ingredients. Organic phosphates also play a role in controlled drug release and in improving the absorption of certain medications.
Organic phosphonates contain a phosphonate group (-PO₃H₂) in which the phosphorus atom is bonded to a carbon atom and two oxygen groups. These compounds have important pharmacological properties, particularly in enzyme inhibition and biochemical process modulation. Organic phosphonates are used in the production of APIs that target bone metabolism, bacterial infections, or antiviral treatments due to their specific biological effects.
At CymitQuimica, we offer organic phosphates and phosphonates for research in medicinal chemistry, biochemistry, and the development of advanced formulations.
Found 1201 products of "Organic Phosphates and Phosphonates"
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3-(Methylnitrosamino)propionitrile
CAS:Controlled Product<p>Applications 3-(Methylnitrosamino)propionitrile (MNPN) was detected for the 1st time in the saliva of betel quid chewers and is a potent carcinogen.<br>References Bartsch, H., et al.: Mutat. Res., 250, 103 (1991), Su, T., et al.: Drug Metab. Dispos., 24, 884 (1996), Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001),<br></p>Formula:C4H7N3OColor and Shape:Light YellowMolecular weight:113.12Triisopropyl Phosphate
CAS:Controlled Product<p>Applications Triisopropyl Phosphate can be used as a flame retardant and catalyst.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, Tie-jiang.: Meitan Jishu,29(2), 204-206 (2010);Chen, Yong-Fu, et al.: Jingxi Huagong, 17(9), 541-543 (2000)<br></p>Formula:C9H21O4PColor and Shape:NeatMolecular weight:224.23Risedronic Acid-d4 (Major)
CAS:Controlled ProductFormula:C7H7D4NO7P2Color and Shape:NeatMolecular weight:287.14Alendronic Acid-d6 (Major)
CAS:Controlled ProductFormula:C4D6H7NO7P2Color and Shape:NeatMolecular weight:255.13Metaraminol Bitartrate
CAS:Controlled Product<p>Applications Metaraminol Bitartrate is a vasopressor comparable to ephedrine used in the maintenance of arterial pressure during spinal anesthesia. Also used in the treatment of hypotension while under the effect of anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ngan, K. et al.: Anesthes., 95, 307 (2001); Critchley, L. et al.: Br. J. Anaesth., 76, 734 (1996);<br></p>Formula:C9H13NO2·C4H6O6Color and Shape:WhiteMolecular weight:317.29(4-Amino-1-hydroxybutane-1,1-diyl)diphosphonic acid
CAS:Purity:95.0%Color and Shape:Solid, White to slightly pale yellow powderMolecular weight:249.0959930419922Cyclophosphamide-d8 H2O [bis(2-chloroethyl-d4)]
CAS:Controlled Product<p>Applications Cyclophosphamide-d8 H2O [bis(2-chloroethyl-d4)] is a useful isotopically labeled compound of Cyclophosphamide Monohydrate (C988580)<br></p>Formula:C7H9D8Cl2N2O3PColor and Shape:White To Off-WhiteMolecular weight:287.15Diazinon
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications A cholinesterase inhibitor; a nonsystemic organophosphate insecticide. This compound is a contaminant of emerging concern (CECs). Used as a standard for Pesticide detection.Diazinon is useful in cannabis testing kits as a component of pesticide mixes (P698230).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gaines, T.B., et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969);<br></p>Formula:C12H21N2O3PSColor and Shape:ColourlessMolecular weight:304.35Cyclophosphamide-d4
CAS:Controlled Product<p>Applications It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),<br></p>Formula:C72H4H11Cl2N2O2PColor and Shape:Off-WhiteMolecular weight:265.11Amifostine Thiol Dihydrochloride >90%
CAS:<p>Stability Hygroscopic<br>Applications Amifostine Thiol is a metabolite of Amifostine (A576810) which provides normal cells with selective protection against the toxic effects of cancer chemotherapy and radiation treatment.<br>References Satge, J., et al.: Eur. J. Med. Chem., 24, 48 (1989); Geary, R.S., et al.: Biopharm. Drug Dispos., 12, 261 (1991); Brown, D.Q., et al. Pharmacol. Ther., 39, 159 (1988); Capizzi, R.L., et al.: Cancer, 72, 3495 (1993); Treskes, M., et al.: Cancer Chemother. Pharmacol., 33, 93 (1993)<br></p>Formula:C5H14N2S·2ClHPurity:>90%Color and Shape:NeatMolecular weight:207.16Carboxyphosphamide-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Cyclophosphamide (CPA) (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Takamizawa, A., et al.: J. Med. Chem., 18, 376 (1975), Jones, R.J., et al.: J. Hematother., 1, 343 (1992), Biggs, D., et al.: Prog. Clin. Biol. Res., 389, 9 (1994),<br></p>Formula:C7H11D4Cl2N2O4PColor and Shape:NeatMolecular weight:297.11(R,S)-4-Hydroxy Cyclophosphamide Preparation Kit
CAS:<p>Stability Unstable in Solution<br>Applications A metabolite of Cyclophosphamide.This Kit consists of a vial of the precursor, 4-hydroperoxycyclophosphamide (H714675), and a vial of sodium thiosulfate (S673640). Simply add water to the reducing agent until it is completely dissolved and add this solution to the precursor. This solution has a half-life of approximately 200 minutes at room temperature. Detailed instructions are enclosed.<br>References Peter, G., et al.: Cancer. Chemother. Pharmacol., 3, 181 (1979), Fenselau, C., et al.: Drug Metab. Dispos., 10, 636 (1982), Gamcsik, M., et al.: J. Med. Chem., 33, 1009 (1990), Habib, A., et al.: Biochem. Pharmacol., 50, 429 (1995),<br></p>Formula:C7H15Cl2N2O3PColor and Shape:Off White CrystallineMolecular weight:277.09Malathion α-Monoacid
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications A major biodegradation product of Malathion (M111000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, Y. et al.: Chemosphere, 60, 1349 (2005); Yoshii, K. et al.: J. Health Sci., 54, 535 (2008); Hayasaka, M. et al.: Jap. J. Forensic Toxicol., 12, 15 (1994);<br></p>Formula:C8H15O6PS2Color and Shape:NeatMolecular weight:302.3Zoledronic Acid Disodium Salt Tetrahydrate
CAS:Controlled Product<p>Applications A biphosphonate bone resorption inhibitor.<br>References Green, J.R., et al.: J. Bone Min. Res., 9, 745 (1994), Risser, F., et al.: J. Pharm. Biomed. Anal., 15, 1877 (1997), Body, J.J., Cancer, 80, 1699 (1997),<br></p>Formula:C5H8N2O7P2·2Na·4H2OColor and Shape:NeatMolecular weight:388.11Imidazol-1-yl-acetic Acid
CAS:Controlled Product<p>Applications An impurity arising in the synthesis of zoledronic acid (Z623500).<br></p>Formula:C5H6N2O2Color and Shape:BeigeMolecular weight:126.115-Decyano 5-Carboxymilrinone
CAS:Controlled Product<p>Impurity Milrinone Impurity 12<br>Applications 5-Decyano 5-Carboxymilrinone (Milrinone Impurity 12) is an impurity of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.<br>References Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983); Maskin, C.S., et al.: Circulation, 67, 1065 (1983); Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983); Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983)<br></p>Formula:C12H10N2O3Color and Shape:Off-WhiteMolecular weight:230.22Deferasirox Methyl Ester
CAS:Controlled Product<p>Applications Deferasirox Methyl Ester is a derivative of Deferasirox (D228650); an orally active tridentate iron chelator.<br>References Hershko, C., et al.: Blood, 97, 1115 (2001); Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003); Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003)<br></p>Formula:C22H17N3O4Color and Shape:White To BeigeMolecular weight:387.39Parathion
CAS:Controlled Product<p>Stability Hygroscopic, Moisture Sensitive<br>Applications Parathion is an organophosphate insecticide used on cotton, rice and fruit trees.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Seifert, J., et al.: Environ. Toxicol. Pharmacol., 35, 200 (2013); Ciffroy, P., et al.: Environ. Toxicol. Chem., 32, 602 (2013);<br></p>Formula:C10H14NO5PSColor and Shape:YellowMolecular weight:291.26
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