Organic Sulphonates and Sulphates
Sulphonates are compounds that contain a functional -SO₃ group, where a sulphur atom is bonded to three oxygen atoms, with one of them linked to an alkyl or aryl group. These compounds are used in API formulation due to their ability to enhance the solubility and stability of active ingredients. Their structure can also confer antimicrobial or anti-inflammatory properties.
Organic sulphates are derivatives of sulphuric acid, where the -OSO₃ group is attached to a carbon atom within an organic structure. They are employed in the manufacture of certain APIs to modify the solubility and bioactivity of compounds. Sulphates are also useful for improving the bioavailability of certain active ingredients in pharmaceutical treatments.
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Found 10406 products of "Organic Sulphonates and Sulphates"
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2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine]
CAS:<p>2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] is a chemical compound that is used as a lead to develop new drugs against malaria. It inhibits the growth of plasmodium falciparum and has been shown to be active in high-throughput screening assays. 2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] may serve as an active molecule for the treatment of malaria in combination with other antiplasmodial agents. The drug discovery process prioritized this compound because it is an asexual stage inhibitor and has gametocyte inhibitory activities.</p>Formula:C24H28N8O4Purity:Min. 95%Molecular weight:492.53 g/mol1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine
CAS:<p>1,4-Bis[(tetrahydro-2-furanyl)carbonyl]-piperazine is a synthetic drug product. It is used as an analytical standard to help elucidate the metabolic pathway of drugs and their metabolites. This compound has been shown to be metabolized by various enzymes including CYP450, glutathione reductase, and esterases. It can also be synthesized from 1,4-dihydropyridine and 2-furancarboxaldehyde. The physical properties of 1,4-bis[(tetrahydro-2-furanyl)carbonyl]-piperazine are: white powder; mp 178°C; IR max 1710 cm−1 (CO); UV max 221 nm (EtOH). The impurities in this product are: 1-(2H)-Quinolinone (CAS No. 2467-94-1) which may have a maximum concentration</p>Formula:C14H22N2O4Purity:Min. 95%Molecular weight:282.34 g/mol1-(2-Furoyl)piperazine
CAS:<p>1-(2-Furoyl)piperazine is a potent inhibitor of tyrosinase, an enzyme involved in the production of melanin. It can be used to treat cancer, as well as hyper-pigmentation disorders such as melasma and chloasma. 1-(2-Furoyl)piperazine inhibits tyrosinase by binding to the active site of the enzyme and blocking its access to substrates. This inhibition prevents the conversion of tyrosine to DOPA and further conversion to melanin. 1-(2-Furoyl)piperazine also inhibits other enzymes in the melanin synthesis pathway, including amine oxidase and dopa oxidase.</p>Formula:C9H12N2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:180.2 g/molBucillamine
CAS:<p>Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.</p>Formula:C7H13NO3S2Purity:99.47%Color and Shape:SolidMolecular weight:223.311,4-Di-2-furoylpiperazine
CAS:<p>1,4-Di-2-furoylpiperazine is a synthetic compound that has been shown to have anti-inflammatory and analgesic properties. It was originally developed as a pharmaceutical drug candidate for the treatment of arthritis and other inflammatory disorders. 1,4-Di-2-furoylpiperazine is an impurity in the synthesis of the drug product diclofenac. The compound is also found as a metabolite in humans after oral administration of diclofenac. 1,4-Di-2-furoylpiperazine binds to protein and inhibits protein synthesis by preventing amino acid incorporation into proteins. It also has nicotinic effects on acetylcholine binding sites and can be used as an analytical standard for HPLC analysis of drugs containing this molecule.</p>Formula:C14H14N2O4Purity:Min. 95%Molecular weight:274.27 g/molBosentan impurity C
CAS:<p>Bosentan impurity C is a stable crystalline compound that is soluble in organic solvents. It has been identified as an impurity of the drug bosentan, and has been found to be present in the drug at concentrations of up to 0.2%. Bosentan impurity C can be prepared by crystallization from an alkaline solution and can also be obtained as a salt form. The salt form is a dimer that consists of two bosentan molecules linked together by one oxygen atom. Bosentan impurity C is stable under normal conditions and does not undergo any changes when exposed to light or heat. This compound has shown no significant adverse effects on humans who have taken it, with no adverse effects on the kidney, liver, or lungs reported.</p>Formula:C52H52N10O10S2Purity:Min. 95%Molecular weight:1,041.16 g/molClopamide
CAS:<p>Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.</p>Formula:C14H20ClN3O3SPurity:99.71%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:345.841-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone
CAS:<p>1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-5-hydroxy-1-pentanone is a drug product that is used as an HPLC standard. It is a natural metabolite of the drug product 1-[4-(4-Amino-6,7-dimethoxyquinazolinyl)-1piperazinyl]-5hydroxypentane. The synthesis of this compound has been reported in the literature.<br>The impurity content of this compound meets the pharmacopoeia requirements for an analytical reference standard for API impurities.</p>Formula:C19H27N5O4Purity:Min. 95%Molecular weight:389.45 g/molN,S-Carboxymethyl cysteine hydrochloride
CAS:<p>N,S-Carboxymethyl cysteine hydrochloride (NCC) is a drug product that is synthesized from cysteine. It has been used in analytical chemistry, metabolism studies, and drug development. NCC has been shown to be a natural metabolite of cysteine when administered orally to rats or mice. It is also an impurity standard for HPLC analysis and has been used as an API impurity in the synthesis of other drugs.<br>NCC is not commercially available but can be synthesized by reacting cysteine with chloroacetic acid and sodium hydroxide.</p>Formula:C7H11NO6S·HClPurity:Min. 95%Molecular weight:273.69 g/mol[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(5S)-tetrahydro-5-methyl-2-furanyl]-methanone
CAS:<p>Furegrelate is an analytical reference standard for the hydroxylation of 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl[(5S)-tetrahydro-5-methyl-2-furanyl]-methanone. Furegrelate is a synthetic drug product that has been used in pharmacological and toxicological research. It is a metabolite of the drug Furosemide, which is used to treat heart failure and high blood pressure. Furegrelate has also been found as an impurity in the API (active pharmaceutical ingredient) of other drugs such as Carvedilol and Metoprolol.</p>Formula:C20H27N5O4Purity:Min. 95%Molecular weight:401.46 g/mol[4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone
CAS:<p>4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone (CAS No. 105356-89-6) is a synthetic impurity standard used in the manufacture of various drugs. Impurities are substances that exist in a mixture with the desired product, but are not an intentional part of that product. Synthetic impurities are created during the synthesis process and are not found in nature. This substance has been shown to be metabolized by cytochrome P450 enzymes and glutathione reductase, and is excreted through urine and bile. It also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>Formula:C18H23N5O4Purity:Min. 95%Molecular weight:373.41 g/molFalimint
CAS:<p>Falimint is a compound with antipyretic and analgesic activity [1].</p>Formula:C11H14N2O4Color and Shape:SolidMolecular weight:238.24Clethodim
CAS:<p>Clethodim is a selective herbicide inhibiting acetyl-CoA carboxylase, effective on grasses with low environmental persistence and moderate toxicity to wildlife.</p>Formula:C17H26ClNO3SPurity:99.99%Color and Shape:Light Yellow LiquidMolecular weight:359.91Spebrutinib besylate
CAS:<p>Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).</p>Formula:C28H28FN5O6SPurity:98%Color and Shape:SolidMolecular weight:581.62Metsulfuron-methyl
CAS:<p>Metsulfuron-methyl: systemic, selective, sulfonylurea herbicide for wheat; targets broadleaf and grass weeds.</p>Formula:C14H15N5O6SPurity:98.52%Color and Shape:Faint Sweet Ester-Like White To Pale Yellow SolidMolecular weight:381.36Flutolanil
CAS:<p>Flutolanil: a fungicide targeting R. solani in rice, toxic to zebrafish.</p>Formula:C17H16F3NO2Color and Shape:SolidMolecular weight:323.31(S)-Terazosin
CAS:<p>(S)-Terazosin is an active S-enantiomer of Terazosin.</p>Formula:C19H25N5O4Color and Shape:SolidMolecular weight:387.43Fomesafen
CAS:<p>Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).</p>Formula:C15H10ClF3N2O6SPurity:99.91% - 99.93%Color and Shape:White Crystalline Solid Fomesafen Is A White Crystalline Solid Used As An HerbicideMolecular weight:438.76Cromoglicate sodium hydrate
CAS:<p>Cromoglicic acid stabilizes mast cells, preventing histamine release, but has been superseded by leukotriene antagonists in asthma treatment.</p>Formula:C23H24Na2O15Color and Shape:SolidMolecular weight:586.41Azafenidin
CAS:<p>Azafenidin: Herbicide for fruit crops like pineapple and citrus, inhibits protoporphyrinogen oxidase (EC 1.3.3.4).</p>Formula:C15H13Cl2N3O2Color and Shape:SolidMolecular weight:338.19
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