Fatty Acids and Lypidic Derivatives

<p>Applications D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus.<br>References Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009); Springhorn, C. et al.: J. Clin. Endocrinol. Metab., 97, 4640 (2012); Hashimoto, K. et al.: J. Clin. Endocrinol. Metab., 97, 3016 (2012); Avelange, M. et al.: Plant. Phys., 94, 1157 (1990); Cramer, C. et al.: J. Chem. Soc., 115, 5745 (1993);<br></p>

<p>Applications Orlistat isomer. Used in the asymmetric synthesis of Orlistat (O686500).<br>References Barbier, P., et al.: Helv. Chimica Acta, 70, 196 (1987),<br></p>

<p>Applications N-Lauroylsarcosine is an anionic surfactant. Its microbicidal action against herpes simplex type 2 (HSV-2) intravaginal infection in a murine model has been investigated.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Roy, S., et al.: Antimicrobial Agents and Chemotherapy, 45, 1671-1681 (2001);<br></p>

<p>Applications Desmethyl Fondenafil is an impurity of the drug Fondenafil/Carbodenafil (F685400) a Sildenafil (S435000) related compound found in health foods.<br>References Hamilton, et al.: J. Med. Chem., 30, 91 (1987),<br></p>

<p>Applications 3-Oxo-7a-hydroxy-5β-cholanoic Acid is a keto bile acid derivative.<br>References Bortolini, O. et al.: Tetra., 62, 4482 (2006); Bortolini, O. et al.: J. Org. Chem., 67, 5802 (2002);<br></p>

<p>Applications Bis(2-ethylhexyl) Azelaate is used in the preparation of plasticizers.<br>References Nakajima, N.Nakajima, N. et al.: J. App. Polym. Sci., 95, 448 (2005); van Oosterhout, J. et al.: Polym., 44, 8081 (2003);<br></p>

<p>Applications Hydroxythiovardenafil is a hydroxylated thiol analogue of the PDE 5 inhibitor Vardenafil (H995300).<br></p>

<p>Stability Light Sensitive<br>Applications Prostaglandin D2 is a fatty acid compound present in the human body. Elevated levels of localized Prostaglandin D2 has been linked to hair loss and growth inhibition. It has also been seen to contribute to the activity of allergic asthma.<br>References Matsuoka, T. et al.: Science., 287, 2013 (2000); Luis, G. et al.: Sci. Transl., 4, 126 (2012);<br></p>

<p>Applications Antilipemic.<br>References Chang, et al.: Biochem. Pharmacol., 16, 2053 (1967), Walsh, et al.: Arch. Biochem. Biophys., 130, 7 (1969), Witiak, et al.: J. Med. Chem., 14, 754 (1971),<br></p>

<p>Applications A deuterated metabolite of Simvastin (S485000). A competitive inhibitor of HMG-CoA reductase.<br>References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),<br></p>

<p>Impurity Orlistat USP Related Compound D<br>Applications N-Formyl-L-leucine (3S,4R,6S)-3-Hexyltetrahydro-2-oxo-6-undecyl-2H-pyran-4-yl ester is an impurity of Orlistat (O686500). Orlistat USP Related Compound D.<br>References Stalder, H., et al.: Helv. Chim. Acta , 75, 1593 (1992),<br></p>

<p>Applications Anti-inflammatory. Selective cyclooxygenase-2 (COX-2) inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Glasson, et al.: Biochem, Pharmacol., 18, 633 (1969), Boissier, et al.: Therapie, 26, 211 (1971), Sorenson, J.R.J., et al.: J. Med. Chem., 19, 135 (1976), Barnett, J., et al.: Biochim. Biophys. Acta, 1209, 130 (1994), Johnson, J.L., et al.: Arch. Biochem. Biophys., 324, 26 (1995),<br></p>