Fatty Acids and Lypidic Derivatives

<p>M02150 - SNAP</p>

<p>Stability Hygroscopic<br>Applications Salinomycin is a potassium ionophore antibiotic. Studies showed that Salinomycin can selectively kill breast cancer stem cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Garcia-Rubino, M. E., et al.: Anticancer Agents Med Chem. 16, 1230 (2016); Boesch, M., et al.: Stem Cells Transl Med 4, 1028 (2015)<br></p>

<p>M02962 - H-Thr-OH</p>

<p>Applications A bile acid which stimulates the flow of bile salts, for potential treatment of Irritable Bile Syndrome.<br>References Gnewuch, C., et al.: World J. Gastroenterol., 15, 3134 (2009), Yu, B., et al.: J. Nat. Prod., 72, 24 (2009), Lim, S., et al.: Int. J. Cancer, 126, 1582 (2010),<br></p>

<p>Applications A degradation product of Orlistat (O686500).<br>References Stalder, H. et al.: Helv. Chim. Acta, 73, 1022 (1990);<br></p>

<p>Stability Hygroscopic<br>Applications Salicylic Acid 2-O-β-D-Glucoside (SAG) is the predominant glycosylated metabolite of Salicylic Acid (S088125); a compound that plays an important role in plants, mostly in the induction of systemic acquired resistance (SAR) against pathogens.<br>References Huang, W.E., et al.: Plant J., 46, 1073 (2006)<br></p>

<p>Applications Perfluoroundecanoic acid is used in biological studies to evaluate perfluorinated compounds level in raw and cooked Mediterranean finfish and shellfish in Greek diet.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vassiliadou, I., et al.: Chemosphere, 127, 117 (2015);<br></p>

<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>

<p>Applications 3’,5’-Dihydrodiol Simvastatin is a metabolite of Simvastatin (S485000).<br>References Vyas, K.P., et al.: Drug Metab. Sispos., 18, 203 (1990); Nakamura, T., et al.: Xenobiotica, 21, 277 (1991); Cheng, H., et al.: Drug Metab. Dispos., 22, 139 (1994);<br></p>