Fatty Acids and Lypidic Derivatives

Applications Acetaminotadalafil, is a new analogue of Tadalafil (T004500), used for the treatment of erectile dysfunction. It acts as a phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005),

Applications A serum lipid regulating agent used as an antihyperlipoproteinemic.This compound is a contaminant of emerging concern (CECs).
References Kissebach, A.H., et al.: Atherosclerosis, 24, 199 (1976), Lewis, J.E., et al.: Pract. Cardiol., 9, 99 (1983), Rubins, H.B., et al.: N. Engl. J. Med., 341, 410 (1999)

Impurity Ezetimibe Desfluoroaniline Analog (USP)
Stability Hygroscopic
Applications An impurity of the cholesterol absorption inhibitor Ezetimibe (E975000). Ezetimibe Desfluoroaniline Analog (USP).
References Anon.: IP.com J., 7, 4 (2007);