Fatty Acids and Lypidic Derivatives

Stability Hygroscopic
Applications Tadalafil. A phosphodiesterase 5 inhibitor.

Applications 3-Hydroxy-7,12-diketocholanoic Acid is a bile acid salt as biosurfactants.
References Posa, M., et al.: Steroids, 86, 16-25 (2014)

Applications Taurinamide is a derivative of Taurolidine; a drug with antimicrobial and antiendotoxic properties.
References Stendel, Ruediger., et al.: Clin. Pharmacokinet., 46(6), 513-524 (2007); Gong, Li., et al.: J. Clin. Pharmacol., 47(6), 697-703 (2007)

Stability Hygroscopic
Applications Deuterated Simvastatin, a competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic.
References Hoffman, W.F., et al.: J. Med. Chem., 29, 849 (1986), Mol, M.J., et al.: Lancet, 2, 936 (1986),

Stability Hygroscopic, Light Sensitive, Temperature Sensitive
Applications An intermediate in the Maillard reaction of proteins with glucose, which is metabolised to 3-Deoxyfructose. An intermediate in the formation of pyrraline, which might contribute to a pathological effect, such as carcinogenesis.
References Kato, H. et al.: Agric. Biol. Chem., 51, 683 (1987), Hayase, F. et al.: J. Biol. Chem., 264, 3758 (1989), Kato, H. et al.: Biochimica et Biophysica Acta, 1035, 71 (1990)