Food Industry Standards

<p>Applications 11-Aminoundecanoic Acid is used to prepare thapsigargin analogues targeting apoptosis to prostatic cancer cells. It is also used to synthesize N-carboxyalkylpeptides containing extended alkyl residues at P1'as matrix metalloproteinase inhibitors.<br>References Jakobsen, C., et al.: J. Med. Chem., 44, 4696 (2001); Esser, C., et al.: Bioorg. Med. Chem. Lett., 5, 539 (1995)<br></p>

<p>Applications AMOZ-HN is a metabolite of Nitrofuran (N493840, 2-Nitrofuran).<br>References Du, N., et al.: J. Chromat., 1327, 90 (2014)<br></p>

<p>Applications Induced mutation of dodecanedioic acid producing Candida tropicalis. Used in cosmetic compositions.<br>References Ardawi, M., et al.: Biochem. J., 212, 835 ( 1983), Renner, F., et al.: J. Lipid Res., 27, 72 (1986), Gu, H., et al.: Anal. Chem., 79, 89 (2007),<br></p>

<p>Applications Labelled analogue of Di-n-propyl Phthalate, a phthalate metabolite of Di-n-butyl phthalate (D429495) degradation with potential genotoxic effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fromme, H. et al.: Environ. Int., 37, 715 (2011); Cao, X.-L.: Comp. Rev. Food Sci. Food Safety, 9, 21 (2010); Begum, A. et al.: Chem. Lett., 33, 682 (2004);<br></p>

<p>Applications Dibenzoylmethane is a compound known to inhibit tumorigenesis in mice.<br>References Lin, C. C., et al.: Cancer Lett., 168, 125 (2001)<br></p>

<p>Applications 5-Ethyl-4-hydroxy-2-methyl-3(2H)-furanone, mixture of isomers 96%, FG (cas# 27538-09-6) is a useful research chemical.<br></p>

<p>Applications Hexacosanoic Acid (cas# 506-46-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,​9-​Decadiene is used in acyclic diene metathesis copolymerization (ADMET) along with 1, 5-hexadiene to form polybutadiene –polyoctenamer copolymers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wagener, K.B., et al.: Macromolecules, 23, 5155-57 (1990);<br></p>

<p>Applications Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells.<br>References Lee, H., et al.: J. Immunol., 185, 6698 (2010); Hsieh, T.J., et al.: Food. Chem. Toxicol., 42, 843 (2004);<br></p>

<p>Applications Methacrylamide (cas# 79-39-0) is a useful research chemical.<br></p>

<p>Applications 1,​1,​1,​2-​Tetrachloroethane is a chlorinated hydrocarbon and used as a solvent for cellulose, acetate, fat, waxes, greases, rubber, and sulfur. It is a contaminant in groundwater. 1,​1,​1,​2-​Tetrachloroethane can also induce heptotoxicity.Environmental contaminants; food contaminants.<br>References Lorah, M. M., and Olsen, L. D. Environ. Sci. Technol. 33, 227 (1999); Zheng, R. D., et al.: J Dig Dis. 13, 321 (2012)<br></p>

<p>Applications Nonadecane is a long chain saturated aliphatic hydrocarbon. Nonadecane is found in tar from coal and other forssil organic matter. Nonadecane is used as a fragrance agent in cosmetics and perfumes.<br>References Youtcheff, J.J. et al.: Org. Geochem., 5, 157 (1983): Etienne, J.J.: Riv. Ital. EPPOS, 15, 418 (1997);<br></p>

<p>Applications Ethyl Benzoylformate is a general chemical reagent used in the preparation of diaminoethanediyl bismethylpyridinium salts for designing recyclable organocatalysts.<br>References Lisnyak, V. et al.: J. Org. Chem., 80, 8570 (2015);<br></p>

<p>Applications Tetracosanoic Acid is a chemical component of a dried mushroom powder exhibiting antioxidant properties. It is a long chain fatty acid present in peanut oil.<br>References Carneiro, A. et al: Food Chem., 138, 2168 (2013); Beare-Rogers, J. et al. Pure Appl. Chem., 74, 685 (2001);<br></p>

<p>Applications Suberic Acid is used in the preparation of reduction-sensitive micelles affecting their cellular uptake. This has potential application in delivery of anticancer drugs. It is also used in the fluorescent detection of amidinium-carboxylate and amidinium formation.<br>References Cui, C. et al.: Biomat., 34, 3858 (2013); Kusukawa, T. et al.: Tetra., 68, 9973 (2012);<br></p>

<p>Applications D-Arabinitol, can be used as a diagnostic tool for the detection of fungal infections in neutropenic patients.<br>References Salonen, J.H., et al.: Eur. J. Clin. Microbiol. Infect. Dis., 20, 179 (2001);<br></p>

<p>Applications N,N'-Dimethylurea<br></p>

<p>Applications Tetrabromobisphenol A is a brominated flame retardant in environment.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References de Wit, C.: Chemosphere, 46, 583 (2002); Meerts, I., et al.: Toxicol. Sci., 56, 95 (2000); Darnerudm P.: Environ. Int., 29, 841 (2003)<br></p>

<p>Applications D-(+)-Trehalose is a disaccharide composed of two α-glucose units. D-(+)-Trehalose is used in many processed foods as well as in biopharmaceutical monoclonal antibody formulations. D-(+)-Trehalose is also used as a protein stabilizer.<br>References Bosquillon, C. et al.: J. Cont. Rel., 99, 357 (2004); Arakawa, T. et al.: Adv. Drug Deliv. Rev., 46, 307 (2001); Singh, S.K. et al.: Pharmac. Res., 28, 873 (2011);<br></p>

<p>Applications NPG Glycol is used in the synthesis of tetraphenylporphyrins. Also used in the synthesis of Bryostatin 2, a protein kinase modulator.<br>References Lindsey, J. et al.: J. Org. Chem., 52, 827 (1987); Evans, D. et al.: J. Am. Chem. Soc., 121, 7540 (1999);<br></p>

<p>Applications Lactitol is listed as an excipient in some prescription drugs, such as Adderall. Lactitol is a sugar alcohol used as a replacement bulk sweetener for low calorie foods. It is also used medically as a laxative.<br>References Bolhuis, G., et al.: Drug Dev. Ind. Pharm., 35, 671 (2009); Toda, Y.: New Food Ind., 33, 21 (1991); Egger, B., et al.: Eur. J. Clin. Pharmacol., 37, 205 (1989)<br></p>

<p>Applications 2-(((2-Propylhept-6-en-1-yl)oxy)carbonyl)benzoic Acid-d4 is the isotope labelled analog of 2-(((2-Propylhept-6-en-1-yl)oxy)carbonyl)benzoic Acid. 2-(((2-Propylhept-6-en-1-yl)oxy)carbonyl)benzoic Acid is an intermediate in the synthesis of 6-Hydroxy Monopropylheptylphthalate (M567075), which is a phthalate metabolite originating from a DPHP (B523500) used in plasticizers to improve chemical and physical properties.<br>References Kasper-Sonnenberg, M. et al.: Int. J. Hyg. Env. Health, 215, 373 (2012); Koch, H. et al.: Int. J. Hyg. Env. Health, 214, 188 (2011);<br></p>

<p>Applications 1-Bromo-2-fluorobenzene is used as a reagent in the synthesis of organic compounds inlcuding that of brominated N-arylated carbazoles which are widely useful in organic chemistry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, L., Synthesis, pages ahead of print, (2015);<br></p>

<p>Applications 1,4-Dimethoxybenzene is a useful chemical in organic synthesis.<br>References Digwal, Chander S., et al.: Asian J. of Org. Chem., 7(5), 865-869 (2018);Cai, Zhi-Bin, et al.: RSC Advances, 6(52), 46853-46863 (2016);Lin, Qi, et al.: Soft Matter, 13(39), 7222-7226 (2017)<br></p>

<p>Applications (Z)-11-Octadecenoic Acid, is a natural 18:1 ω-7 fatty acid. It is readily incorporated into triglycerides in perfused liver.<br>References Bickerstaff, R., et al.: Biochem J. 118(3), 433-442 (1970).;<br></p>

<p>Applications Methyl trans,trans-9,12-Octadecadienoate is a useful synthetic intermediate. It is an intermediate used to prepare (±)-trans-9,10-Epoxy-12(E)-octadecenoic acid methyl ester and (±)-trans-12,13-Epoxy-12(E)-octadecenoic acid methyl ester. It is also a biodiesel component that provides lubricity enhancement.<br>References Knothe, G., et al.: Fuel, 84, 1059 (2005); Knothe, G., et al.: Energy &amp; Fuels, 19, 1192 (2005)<br></p>

<p>Applications 1-PENTEN-3-OL (cas# 616-25-1) is a useful research chemical.<br></p>

<p>Applications 5-Hydroxy-7-methoxy-2-phenyl-4H-chromen-4-one (cas# 520-28-5) is a useful research chemical.<br></p>

<p>Applications α-Methylanisalacetone is used in skin sensitization measuring method.<br>References Fujita, M., et al.: PCT Int. Appl., (2020);<br></p>

<p>Applications Diphenyl Phthalate-3,4,5,6-d4 (CAS# 1398065-61-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Tricosanoic Acid is a saturated fatty acid. It may be used to activate orphan G protein-coupled receptor GPR40.<br>References Briscoe, C., et al.: J. Biol. Chem., 278, 11303 (2003)<br></p>

<p>Applications Triphenylphosphine is used in the synthesis of Chlorambucil with cytotoxicity in breast and pancreatic cancers. Also used in the preparation of α-Tocopherol analogues for monitoring antioxidant status.<br>References Millard, M. et al.: J. Med. Chem., 56, 9170 (2013); Krumova, K. et al.: J. Am. Chem. Soc., 135, 17135 (2013);<br></p>

<p>Applications Butyl Benzoate has a fruity aroma an is commonly employed in food additives and flavorings. Butyl Benzoate is also a useful reagent in synthesis.<br>References Mkhonazi, B., et al.: Molecules., 25, 1040 (2020); Rottiers, H., et al.: Eur. Food Res. Technol., 245, 2459-2478 (2019)<br></p>

<p>Applications Substrate specificity of haloalkane dehalogenases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koudelakova, T., et al.: Biochem. J., 435, 345 (2011),<br></p>

<p>Applications 1,3-Diethyl-2-thiourea (cas# 105-55-5) is a useful research chemical.<br></p>