Food Industry Standards

<p>Applications 2-Hydroxy-1,4-naphthoquinone-5,6,7,8-d4 is the isotope labelled analog of 2-Hydroxy-1,4-naphthoquinone (Lawsone) (H949535); the active ingredient of Lawsonia inermis (henna) leaves extract. Lawsone has potential antimicrobial activity and can be used for the detection of latent fingermarks on paper surfaces.<br>References Tekin, V., et al.: J. Radioanal. Nucl. Ch., (2014); Rahmoun, N.M., et al.: Am. J. Med. Biol. Res., 1, 16 (2013); Jelly, R., et al.: Chem. Commun., 30, 3513 (2008)<br></p>

<p>Applications 2-Phenyl-d5-ethyl Isothiocyanate (CAS# 912627-98-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications m-Salicylic Acid is widely used in organic synthesis. It is also an important active metabolite of aspirin (A187780).<br>References Haynes, M., et al.: CRC H.b Chem. Phys., 92, 306 (2011)<br></p>

<p>Applications AMOZ-HN is a metabolite of Nitrofuran (N493840, 2-Nitrofuran).<br>References Du, N., et al.: J. Chromat., 1327, 90 (2014)<br></p>

<p>Applications Ambrettolide is a macrocyclic lactone that naturally occurs in ambrette seed oil. Ambrettolide is nontoxic, has a musky odour, and is commonly used as a fixative in perfume formulations.<br>References Jellinek, P.: Perfumery, No vol. given, 72 (1997); Majee, R., et al.: J. Indian Chem. Soc., 83, 1179 (2006); Ngassouum, M., et al.: J. Ess. Oil Res., 11, 231 (1999); van der Meulen, I., et al.: Polym. Prepr., 49, 467 (2008)<br></p>

<p>Applications 3-Mercapto-3-methyl-1-butanol (cas# 34300-94-2) is a useful research chemical.<br></p>

<p>Applications 4-Nitro-1,2,3-triazole is a highly impact sensitive and explosive material.<br>References Politzer, P. et al.: Int. J. Quant. Chem., 61, 389 (1997);<br></p>

<p>Applications 1,​9-​Decadiene is used in acyclic diene metathesis copolymerization (ADMET) along with 1, 5-hexadiene to form polybutadiene –polyoctenamer copolymers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wagener, K.B., et al.: Macromolecules, 23, 5155-57 (1990);<br></p>

<p>Applications Pentadecanolide is a monomer used to make PGA-co-pentadecalactone polymers to be used in the development of directly compressed prolonged release tablets of slightly soluble drugs such as ketoprofen.<br>References Jan, S.U., et. al.: AFR. J. Pharm. Pharmacol., 6, 601 (2012)<br></p>

<p>Applications Nonadecane is a long chain saturated aliphatic hydrocarbon. Nonadecane is found in tar from coal and other forssil organic matter. Nonadecane is used as a fragrance agent in cosmetics and perfumes.<br>References Youtcheff, J.J. et al.: Org. Geochem., 5, 157 (1983): Etienne, J.J.: Riv. Ital. EPPOS, 15, 418 (1997);<br></p>

<p>Applications Ethyl Benzoylformate is a general chemical reagent used in the preparation of diaminoethanediyl bismethylpyridinium salts for designing recyclable organocatalysts.<br>References Lisnyak, V. et al.: J. Org. Chem., 80, 8570 (2015);<br></p>

<p>Applications DL-Tyrosine (cas# 556-03-6) is a useful research chemical.<br></p>

<p>Applications N,N'-Dimethylurea<br></p>

<p>Applications D-(+)-Trehalose is a disaccharide composed of two α-glucose units. D-(+)-Trehalose is used in many processed foods as well as in biopharmaceutical monoclonal antibody formulations. D-(+)-Trehalose is also used as a protein stabilizer.<br>References Bosquillon, C. et al.: J. Cont. Rel., 99, 357 (2004); Arakawa, T. et al.: Adv. Drug Deliv. Rev., 46, 307 (2001); Singh, S.K. et al.: Pharmac. Res., 28, 873 (2011);<br></p>

<p>Applications 3,4-Dimethoxybenzaldehyde-d3 is an intermediate in the synthesis of trans-Piceatannol-d3 (P436302), which is an isotope labelled compound of trans-Piceatannol (P436300), which is human metabolite of Resveratrol (R150000).<br>References Athar, M., et al.: Toxicol. Appl. Pharmacol., 224, 274 (2007), Bernhardt, R., et al.: J. Biotechnol., 124, 128 (2006), Fairman, D.A., et al.: Drug Metab. Dispos., 35, 2159 (2007),<br></p>

<p>Applications L-Menthyl Acetate is a component of essential oils extracted from natural sources.<br>References Gowton, C. M., et al.: Sci. Rep., 10, 9090 (2020); Zardo, D. M., et al.: Curr. Bioact. Compds, 15, 592 (2019); Adaszynska, Michalina, et al.: Zywnosc, 20(2), 116-125 (2013);Hashimoto, Gabriela S., et al.: Aquaculture, 450, 182-186 (2016); Mazzucotelli, Maria, et al.: J. of Chrom. A, 1583, 124-135 (2019)<br></p>

<p>Applications Phenyl Acetate is a metabolite of Phenylbutyrate (PB), useful in the treatment of neuroblastoma and lung cancer. An odorant found in strawberries, passion fruit and black tea.<br>References Ubeda, C. et al.; J. Agr. Food Chem. 60, 6095 (2012); Burzynski, S.R. &amp; Nagy-Kubove, E.; J. Cancer Ther. 2, 518 (2011); Brat, P. et al.; J. Agr. Food Chem., 48, 6210 (2000); Mick, W. &amp; Schreier, P.; J. Agr. Food Chem., 32, 924 (1984)<br></p>

<p>Applications 1-Bromo-2-fluorobenzene is used as a reagent in the synthesis of organic compounds inlcuding that of brominated N-arylated carbazoles which are widely useful in organic chemistry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, L., Synthesis, pages ahead of print, (2015);<br></p>

<p>Applications 1,4-Dimethoxybenzene is a useful chemical in organic synthesis.<br>References Digwal, Chander S., et al.: Asian J. of Org. Chem., 7(5), 865-869 (2018);Cai, Zhi-Bin, et al.: RSC Advances, 6(52), 46853-46863 (2016);Lin, Qi, et al.: Soft Matter, 13(39), 7222-7226 (2017)<br></p>

<p>Applications (Z)-11-Octadecenoic Acid, is a natural 18:1 ω-7 fatty acid. It is readily incorporated into triglycerides in perfused liver.<br>References Bickerstaff, R., et al.: Biochem J. 118(3), 433-442 (1970).;<br></p>

<p>Applications Erucic acid is a long-chain alcohol that acts as an inhibitor of fatty acid oxidation in the heart. Erucic acid originates in rapeseed plants, and is the major fatty acid constituent of rapeseed plant oil extracts and canola oil.<br>References Christophersen, B. &amp; Bremer, J.: BBA-Lipid. Lipid Met., 280, 506 (1972); Ecke, W., et al.: Theor. Appl. Gen., 91, 972 (1995); Metz, J., et al.: Plant Phys., 122, 635 (2000)<br></p>

<p>Applications α-Methylanisalacetone is used in skin sensitization measuring method.<br>References Fujita, M., et al.: PCT Int. Appl., (2020);<br></p>

<p>Applications 1,4-Butanediol Dimethylacrylate used in preparation method and application of Hydrogel superabsorbent polymer.<br>References Woo, H., et al.: PCT Int. Appl., (2020);<br></p>

<p>Applications Diphenyl Phthalate-3,4,5,6-d4 (CAS# 1398065-61-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Bis[(±)-2-ethylhexyl] Phthalate-d38 (CAS# 352431-42-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3-Diethyl-2-thiourea (cas# 105-55-5) is a useful research chemical.<br></p>

<p>Applications Bis(5-methylhexyl) Phthalate works as a plasticizer.<br>References Lai, Y., et al.: J. Agri. Food Chem., 61, 5286 (2013); Park, G., et al.: J. Membrane Sci., 18, 177 (1984)<br></p>

<p>Applications A derivative of dioxane.<br></p>

<p>Applications: D-(+)-3-Phenyllactic Acid is an 3-aryl analogue of D-Lactic acid with antimicrobial activity. D-(+)-3-Phenyllactic Acid is partiularly effective in inhibiting the growth of Listeria monocytogenes.<br>References Dieuleveux, V. et al.: Int. J. Food Microbiol., 40, 177 (1998); Dieuleveux, V. et al.: J. Food Prot., 61, 1281 (1998);<br></p>

<p>Applications Bis(2-ethoxyethyl) Phthalate-3,4,5,6-d4 (CAS# 1398066-12-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Monoundecyl Phthalate is a phthalate monoesters on gap junctional intercellular communication and peroxisome proliferation in rodent and primate hepatocyte.<br>References Kamendulis, L.M., et al.: J. Toxicol. Environ. Health., 65, 569 (2002);<br></p>

<p>Applications 2-Phenyl-d5-ethan-1,1,2,2-d4-ol (CAS# 42950-74-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Ergosine is an ergot alkaloid which are used in the treatment of vasoconstriction and as well as Parkinson’s disease. Also certain derivatives act as psychedelics mimicking lysergic acid.<br>References Martucci N. et al.: Cephal., 1, 151 (1983); Kehr, W. et al.: Eur. J. Phamracol., 41, 261 (1977);<br></p>