Pharmaceutical and Veterinary Compounds and Metabolites

<p>Lysinoalanine is an unusual amino acid, not a dipeptide, which exists in proteins of cooked foods. It is formed in food that is heated or treated with alkali.</p>

<p>Cellulose, an excipient, aids stability, solubility, and processing of drugs and affects their ADME.</p>

<p>Monoglyceridelipase is a crucial enzyme involved in lipid metabolism, catalyzing the hydrolysis of monoglycerides (especially 2-AG, or 2-arachidonoylglycerol) into glycerol and free fatty acids. By regulating the levels of 2-AG, this enzyme impacts neural signaling, pain perception, inflammatory responses, and metabolic processes.</p>

<p>N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription.</p>

<p>Atrazine mercapturate, a major atrazine metabolite from glutathione, is detectable in urine and linked to cancer, reproductive, and endocrine issues.</p>

<p>Cortisol sulfate sodium, a Cortisol metabolite, binds specifically to intracellular transcortin.</p>

<p>D-Glyceric acid, found in urine, aids in Primary hyperoxaluria I &amp; Glutaric Acidemia II research.</p>

<p>Compound 7a, Methyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate, is a metabolite of bile acid.</p>

<p>GPI, also PGI or PHI, is a conserved dimeric glycolytic enzyme, catalyzing glucose-6-phosphate to fructose-6-phosphate isomerization.</p>

<p>Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed</p>

<p>Oleic acid-2,6-diisopropylanilide: ACAT inhibitor, IC50 7 nM; lowers LDL &amp; raises HDL in high-fat fed rabbits/rats at 0.05%.</p>

<p>12α-Hydroxysteroid dehydrogenase, an NAD-dependent enzyme expressed in Bacillus sphaericus, actively processes both free and conjugated bile salts. It is utilized to determine the levels of 12α-hydroxy bile acids in serum.</p>

<p>3-Hydroxysebacic acid, an endogenous metabolite found in urine, is utilized in the study of Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) [1] [2].</p>

<p>2-Methylnicotinamide is an endogenous metabolite of nicotinamide and can be used for related research in the life sciences.</p>

<p>P-orlandin, a fungal compound, blocks FREP1, halting P. falciparum's mosquito infection.</p>

<p>Sorbitol-6-phosphate 2-dehydrogenase, a dehydrogenase enzyme produced by Escherichia coli, catalyzes the interconversion of D-sorbitol 6-phosphate and D-fructose 6-phosphate. The enzyme oxidizes D-sorbitol 6-phosphate at a rate ten times faster than it reduces D-fructose 6-phosphate, playing a role in various cellular processes.</p>

<p>A unique collection of 4454 human metabolites for high-throughput, high-content screening.</p>

<p>4β-hydroxy Cholesterol is a useful organic compound for research related to life sciences. The catalog number is T21530 and the CAS number is 17320-10-4.</p>

<p>Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] .</p>

<p>9-cis-Vitamin A palmitate, a 9-cis isomer in corn flakes, has 26% activity of all-trans-vitamin A, the most active form.</p>

<p>N-Acetyl-α-D-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, plays a crucial role as an intermediate in the biosynthesis of N-linked</p>

<p>Streptolysin O: lyses cells, cardiotoxic, used for cell permeabilization, has active and inactive states.</p>

<p>L-α-Aminoadipic Acid exhibits biological activity against metabotropic glutamate receptors and can be used in biochemical experiments and drug synthesis.</p>

<p>IAGNH, a glycosidase, breaks N-glycosidic bonds in nucleosides, recycling nucleobases and ribose.</p>

<p>ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.</p>

<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>

<p>Pregnant mare serum gonadotropin (PMSG) functions as a gonadotropin that enhances follicular development and ovulation in animals. This compound operates by modulating blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. Commonly employed in livestock to boost reproductive efficiency, PMSG is also valuable for research focused on estrous cycle regulation.</p>

<p>Diacetinase, a member of the esterase family, catalyzes the hydrolysis of glyceryl diacetate (Diacetin). It is utilized in the measurement of lipase activity.</p>

<p>Manoyl oxide is a proposed intermediate in the biosynthesis of forskolin and other medically important labdane-type terpenoids.</p>

<p>Sarcophine is a natural cembranoid from the Red Sea soft coral Sarcophyton glaucum.</p>

<p>12(S)-HETE, from arachidonic acid via 12-lipoxygenase, is found in platelets and leukocytes, aids tumor cell adhesion, with a derivative used in research.</p>

Beta-Galactose dehydrogenase converts galactose to galactonolactone, reducing NAD to fluorescent NADH; useful in galactose measurement.

<p>(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid displays EC50 values of 73.5 μM against T. cruzi. trypomastigotes.</p>

<p>8-Isoprostaglandin F2α is a natural product for research related to life sciences. The catalog number is T37164 and the CAS number is 27415-26-5.</p>

<p>Ethylenediaminediacetic acid is derived from two molecules of glycine linked by amines.</p>

<p>Glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is an enzyme that catalyzes the oxidation of glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DHAP), playing a crucial role in glycerol metabolism and energy production. This enzyme acts as the rate-limiting step in glycerol production within Saccharomyces cerevisiae, regulating glycerol formation and accumulation to aid the yeast in adapting to hyperosmotic environments. Additionally, glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is relevant in research within the field of metabolic engineering.</p>

<p>9(R)-HODE cholesteryl ester, from atherosclerotic lesions, may form enzymatically or by lipid peroxidation; used as a chiral analysis standard.</p>

<p>Cyperine is a useful organic compound for research related to life sciences. The catalog number is T125020 and the CAS number is 33716-82-4.</p>

<p>7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, is utilized in the synthesis of mRNA cap analogues[1].</p>

<p>Doxorubicinol is the major circulating metabolite of doxorubicin with antineoplastic acitivity.</p>

<p>Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".</p>

<p>F-14329 is a tetramic acid fungal metabolite [1] .</p>

<p>FR106969 is a platelet activating factor antagonist isolated from fungus with anti-inflammatory activity.</p>

<p>Maximiscin, a metabolite derived from fungi, causes DNA damage and exhibits selective cytotoxic activity towards a specific subtype of triple-negative breast</p>

<p>Coproporphyrin III is a derivative of porphyrin.</p>

<p>Homocarnosine TFA: brain-exclusive GABA-histidine dipeptide, neuronal, anticonvulsant, antioxidant, anti-inflammatory.</p>

<p>D-Sedoheptulose 7-phosphate, a precursor to group III heptaic acid and group IV hygromycin B, converts to NDP-heptose via similar pathways.</p>

<p>L-Lysine, sulfite (2:1) is a drug/ therapeutic agent.</p>

<p>2-(2',3',4'-Trihydroxybutyl)quinoxaline is a food metabolite.</p>

<p>Estriol 16α-(β-D-glucuronide), an endogenous metabolite found in urine, is utilized in pregnancy research [1] [2].</p>