Amino Acids (AA)

Amino acid

Amino acid

Glutamic acid

Amino acid

Amino acid

Nitrogen heterocyclic compound

Amino acid

Amino acid

Nitrogen heterocyclic compound

Nitrogen heterocyclic compound

Acyclic amide

Amino acid

Amino acid

Organo-sulphur compound

Methionine

<p>Applications 1-Methyl-4-nitropyrrole-2-carboxylic Acid is used in the synthesis of Lexitropsin and distamycin analogs with antimicrobial activities.<br>References Anthony, N., et al.: J. Med. Chem., 50, 6116 (2007); Khalaf, A., et al.: J. Med. Chem., 47, 2133 (2004)<br></p>

<p>Applications H-Val-Gly-OH (cas# 686-43-1) is a useful research chemical.<br></p>

<p>Applications Perfluoro(4-methyl-3,6-dioxaoct-7-ene)sulfonyl Fluoride is used as a reagent in the synthesis of novel perfluorinated vinyl ether containing sulfonimide functionality which can be copolymered with tetrafluoroethylene to yield a novel perfluorinated copolymer.<br>References Zhu, S., et al.: Chinese J. Chem., 21, 921 (2003);<br></p>

<p>Applications N-Methylformanilide is an aromatic reagent used in the synthesis of dye-sensitized solar cells. Also used in the synthesis of potent tyrosinase inhibitors.<br>References Meyer, T et al.: J. Org. Chem., 77, 3704 (2012); Nihei, K. et al.: Bioorg. Med. Chem. Lett., 14, 681 (2004);<br></p>

<p>Applications N-[(Benzyloxy)carbonyl]glycylglycine is a reagent in the synthesis of Glycylglycyl-L-tyrosine (G718500), which is a fungal tyrosinases and their capability to oxidize peptide-bound tyrosine residues is important in a view of applicability of tyrosinases.<br>References Bowness, J., et al.: Biochem. J., 53, 620 (1953), Cuff, M., et al.: J. Mol. Biol., 278, 855 (1998), Kubo, I., et al.: Bioorg. Med. Chem., 12, 5349 (2004),<br></p>

<p>Applications Triuret is a byproduct of purine degradation in living organisms. It is a product from the pyrolsis of urea.<br>References Sergiu P. P., et al:. HHS Public Access, (2010);<br></p>

<p>Applications Tris(2-(2-methoxyethoxy)ethyl)amine (cas# 70384-51-9) is a useful research chemical.<br></p>

<p>Applications 3'-Methylacetophenone is a reagent that is used in the preparation of 3-aryl-6-phenylimidazo[2,1-b]thiazoles which has anticancer properties.<br>References Koppireddi, S., et al.: Bioorg. Med. Chem. Lett., 24, 5428 (2014);<br></p>

<p>Applications Intermediate for the preparation of Naratriptan and other indole sulfonamide derivatives.<br></p>

<p>Applications 1-(4-methyl-3-cyclohexen-1-yl)ethanone is an essential oil found in Cedrus atlantica wood and orange peels.<br>References Uehara, Ayaka, et al.: Phytochemistry, 144, 208-215 (2017); Liu, Bo, et al.: Yancao Keji, (9), 52-56 (2014)<br></p>

<p>Applications 3-Methyl-3-hepten-5-one is a reagent used to prepare fused nitrogen-heterocycles from β-enamino nitrile and α,β-unsaturated carbonyl compounds.<br>References Nemes, P., et al.: Synlett., 2, 222 (1999)<br></p>

<p>Applications Used in the methods of detecting nitrotyrosine and aminotyrosine residues of peptides and proteins. Also used in the studies on the separation and photometric determination of antiepileptics.<br>References Quednow, B., et al.: Pharmazie, 34, 724 (1979),<br></p>

<p>Applications Dihydro-5-methyl-4H-1,3,5-dithiazine is used as a reagent in the synthesis of neovibsanin derivatives which have the ability to induce neuronal differentiation in PC12 cells.<br>References Annette, P.-J. C., et al.: Tetrahedron, 66, 6842 (2010)<br></p>

<p>Applications N-Methyldiethanolamine-13C,d3 Hydrochloride is isotopically labelled salt form of N-Methyldiethanolamine (M301625), which is used as a reagent in the synthesis of broad-spectrum antimicrobial polycarbonate hydrogels with fast degradability. It is also used as a reagent in the synthesis of dihydroxy quaternary ammonium salts with long chain alkyl bromides that can exhibit antibacterial and antifungal activity.<br>References Pascual, A., et al.: Biomacromolecules, 16, 1169 (2015); Liu, W., et al.: Chem. Biol. Drug Des., 85, 91 (2015);<br></p>

<p>Impurity Verapamil EP Impurity K<br>Applications (Verapamil EP Impurity K)<br></p>

<p>Applications Fructose-histidine is an amadori compound formed in food.<br>References Wang, J., et al.: J. Mass Spec., 43, 262 (2008); Hashiba, H.: J. Agri. Food Chem., 24, 70 (1976)<br></p>

<p>Applications N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir (D101500) which nhibits the HCV protein NS5A. Daclatasvir (D101500) can be used as a drug candidate for the treatment of hepatitis C (HCV).<br>References Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);<br></p>

<p>Applications L-Threonine-2,3-d2 (CAS# 1202936-45-5) is a useful isotopically labeled research compound.<br></p>

<p>Impurity Iohexol EP Impurity K<br>Applications 5-Amino-2,4,6-triiodoisophthalic Acid (Iohexol EP Impurity K) is an intermediate for nonionic iodinated X-ray contrast agents.<br></p>

<p>Applications L-Leucine is an essential amino acid. L-Leucine acts as a nutrient signal to stimulate protein synthesis. It has also activates the mammalian target of rapamycin kinase that regulates cell growth.<br>References Demant, T. et al.: Am. J. Physiol., 270, E1022 (1996); Diraison, F. et al.: Am. J. Physiol., 277, E529 (1999); Suryawan, A. et al.: J. Anim. Sci., 89, 2004 (2011); Peyrollier, K. et al.: Biochem. J., 350, 361 (2000);<br></p>

<p>Applications Ethametsulfuron-methyl Sodium Salt, a regulator of the early steps of complement activation on mucosal surfaces. It can be used in combination treatment of ohmic heating with various essential oil components for inactivation of food-​borne pathogens in buffered peptone water and salsa.<br>References Kim, S. S., et al.: Food Control, 80, 29 (2017); Reichhardt, M. P., et al.: Front Immunol, 7, 85 (2016)<br></p>

<p>Applications Labelled L-Citrulline. An amino acid, first isolated from the juice of watermelon, Citrullus vulgaris Schrad., Cucurbitaceae. Used in the treatment of asthenia.<br>References Kurtz, et al.: J. Biol. Chem., 122, 477 (1938), Rajantie, J., et al.: J. Pediatr., 97, 927 (1980), Carpenter, T.O., et al.: N. Engl. J. Med., 312, 290 (1985),<br></p>

<p>Applications Suberylglycine is one of the acylglycines, an important class of metabolites that have been used in the diagnosis of several inborn errors of metabolism (IEM).<br>References Costa, C., et al.: J. Pharmaceut. Biomed. Anal., 21, 1215 (2000), Garcia-Villoria, J., et al.: Clin. Biochem., 42, 2 (2009), Scalbert, A., et al.: Metabolomics, 5, 435 (2009),<br></p>

<p>Applications Intermediate for the preparation of Glimepiride.<br></p>

<p>Applications 3-Methoxy-2',4',6',4-tetrahydroxychalcone piperidine complex (cas# 52218-19-6) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Cysteine is a non-essential amino acid that can be synthesized by the human body under normal physiological conditions if a sufficient quantity of methionine is available. Cysteine is commonly used as a precursor in the food and pharmaceutical industries. Cysteine is used as a processing aid for baking, as an additive in cigarettes, as well as in the preparation of meat flavours.<br>References Hui, N. et al.: Meat Sci. Appl., 74 (2001); Kiviharju, K. et al.: J. Biotechnol., 117, 299 (2005); Pecivova, P. et al.: J. Sci. Food Agric., 90, 1681 (2010);<br></p>

<p>Applications A labelled metabolite of Catecholamines.<br>References Kopin, I.J., et al.: J. Biol. Chem., 236, 2109 (1961), Short, F.W., et al.: J. Med. Pharm. Chem., 5, 642 (1962)<br></p>

<p>Applications 2-Methoxyphenol-3,4,5,6-d4 (CAS# 7329-52-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>

<p>Applications 3-Methyl-1,3,5-pentanetriol is used in the synthesis of Mevalonolactone (M339040), in the synthesis of vitamins and isoprenoids such as steroids.<br>References Yamashita, H. et al.: Frag. J., 28, 62 (2000); Huang, F. et al.: J. Am. Chem. Soc., 97, 4144 (1975);<br></p>

<p>Applications 1-Ethyl-1-methylcyclopentane, is one of the chemical components of Gas-Phase organic carbon emissions from motor vehicles. It is also a volatile component of frying oils.<br>References Gentner, D. R., et al.: Environ. Sci. Tech., 47, 11937 (2013); Prevot, A. Frying Food, 155 (1988);<br></p>

<p>Applications MNC is on the metabolic pathway for 2,4-Dinitotoluene degradation.<br>References Spangoord, R.J., et al.: App. and Environ. Microbiology, 57, 11, 3200 (1991)<br></p>