Amino Acids (AA)

Applications 2-Acrylamide-2-methylpropanesulfonic Acid is used in preparation of PAMPS/PHEMA/PEDOT Hydrogel Polyelectrolyte for activated carbon electrode.
References Zhang, X., et al.: Faming Zhuanli Shenqing, (2020);

Applications 2-Amino-5-methoxybenzoic Acid is used in the synthesis of quinazolinone class of histamine H3 receptor inverse agonists. It is also used in the synthesis of Alogliptin, a selective inhibitor of the serine protease dipeptidyl peptidase IV.
References Feng, J. et al.: J. Med. Chem., 50, 2297 (2007); Nagase, T. et al.: J. Med. Chem., 51, 4780 (2008);

Applications 2-Bromo-5-methylbenzoic acid

Applications 2-methylquinoline-4,6-diamine (cas# 5443-31-2) is a useful research chemical.

Applications 1-Methyl-2-pyrrolidone-d6 is labeled 1-Methyl-2-pyrrolidone (M326120), which is a versatile industrial solvent. NMP is currently approved for use only in veterinary pharmaceuticals. The determination of the disposition and metabolism of NMP in the rat will contribute toward understanding the toxicology of this exogenous chemical which man may likely be exposed to in increasing amounts.
References Southwell, D., et al.: J. Pharm. Pharmacol., 33, 3 (1981); Barry, W., et al.: J. Invest. Dermatol., 82, 49 (1984),

Applications 4-Chloro-3-methyl-benzylamine Hydrochloride is a salt of 4-Chloro-3-methyl-benzenemethanamine (C371115), which is used in the synthesis of stable stearoyl-CoA desaturase (SCD) inhibitors.
References Koltun, D.O., et. al.: Bioorg. Med. Chem. Lett., 19, 2048 (2009)

Applications Methyl 3-amino-2-methylbenzoate (cas# 18583-89-6) is a useful research chemical.

Applications 5-Methoxyindole-3-acetonitrile is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors.
References Van Zandt, M., et al.: J. Med. Chem., 48, 3141 (2005); Wu, J., et al.: Bioorg. Med. Chem. Lett., 17, 4664 (2007);

Applications Ethyl 4-bromo-2-methyl-2-(methylsulfonyl)butanoate can be used to synthesize pyridine methylsulfone hydroxamate LpxC inhibitors for treating bacterial infections.
References Montgomery, J. I. et al.: J. Med. Chem. 55, 1662 (2012); Brown, M. F., et al.: PCT Int. Appl. WO 2012120397 A1 20120913 (2012)

Applications An intermediate in the synthesis of Metoclopramide.
References Murakami, M., et al.: Chem. Pharm. Bull., 19, 1696 (1971),

Applications Methyl 3-formyl-5-methylbenzoate