Amino Acids (AA)

<p>Applications 1,3,5-Trimethoxy-2-methylbenzene AldrichCPR (cas# 14107-97-2) is a useful research chemical.<br></p>

<p>Applications 1-Chloro-4-methoxybutane (cas# 17913-18-7) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Acetyl-L-(-)-leucine is used in the preparation of small molecule inhibitors of anti-apoptotic Bcl-2 family proteins. Also used in the preparation of amphiphilic copolymers involving hydrophobic amino acid and oligopeptide side chains for optical tumor imaging in vivo.<br>References Zheng, C. et al.: Bioorg. Med. Chem. Lett., 22, 39 (2012); Miki, K. et al.: Bull. Chem. Soc. Jap., 85, 1277 (2012);<br></p>

<p>Applications 2-Hydroxy-5-methylpyridine (cas# 1003-68-5) is a useful compound for organic synthesis. In particular it has been used for the diastereoselective preparation of cyclobutane-fused pyridinyl sulfonyl fluorides.<br>References Liu, J., et al.: Org. Biomol. Chem., 18, 4019 (2020)<br></p>

<p>Applications (3-Glycidoxypropyl)triethoxysilane is used in the fabric industry to treat and modify fabrics.<br>References Schramm, Christian, et al.: Coloration Tech., 133(3), 234-242 (2017);Grancaric, Ana Marija, et al.: Pro. in Org. Coatings, 103, 174-181 (2017); Yeo, Jun-Seok, et al.: J. of Ind. and Eng. Chem., 45, 301-306 (2017)<br></p>

<p>Applications 2-bromo-N-methoxy-N-methylbenzamide (cas# 899425-05-9) is a useful research chemical.<br></p>

<p>Applications DMTMM, a conjugating agent that efficiently conjugat PnPS to Luminex microspheres without affecting the antigenicity of a broad set of PnPS.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wrzesien, J. &amp; Graham, D.: Tetrahedron, 68, 1230 (2012); Schlottmann, S. et al.: J. Im. Meth., 309, 75 (2006)<br></p>

<p>Applications β-Alanine-13C3,15N is the isotope labeled analogue of β-Alanine (A637320), which is a naturally occurring beta amino acid. β-Alanine is formed in vivo by the degradation of Dihydro Uracil (D449990) and Carnosine. β-Alanine is also the rate-limiting precursor of Carnosine, as a result supplementation with β-Alanine increases the concentration of Carnosine in muscles.<br>References Derave, W. et al.: J. Appl. Physiol., 103, 1736 (2007); Xia, J.-F. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 977, 1930 (2009); Artioli, G.G. et al.: Med. Sci. Sports Exer.,42, 1162 (2010);<br></p>

<p>Applications Used in the synthesis of DMPO-type spin traps.<br>References Konaka, R., et al.: Free Radical Res., 23, 15 (1995),<br></p>

<p>Applications 3-Methoxycatechol is used to prepare polyphenolic deoxybenzoins as potential antioxidants and tyrosinase inhibitors.<br>References Ng, L., et al.: Bioorg. Med. Chem., 17, 4360 (2009)<br></p>

<p>Stability Hygroscopic<br>Applications 2-Fluoro-4-methylphenylboronic Acid (cas# 170981-26-7) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Methyldiethanolamine-13C,d3 Hydrochloride is isotopically labelled salt form of N-Methyldiethanolamine (M301625), which is used as a reagent in the synthesis of broad-spectrum antimicrobial polycarbonate hydrogels with fast degradability. It is also used as a reagent in the synthesis of dihydroxy quaternary ammonium salts with long chain alkyl bromides that can exhibit antibacterial and antifungal activity.<br>References Pascual, A., et al.: Biomacromolecules, 16, 1169 (2015); Liu, W., et al.: Chem. Biol. Drug Des., 85, 91 (2015);<br></p>

<p>Applications 2-ethyl-6-methylpyrazine (cas# 13925-03-6) is a useful research chemical.<br></p>

<p>Applications 8-Bromo-7-(2-butyn-1-yl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an intermediate used to prepare selective inhibitors of dipeptidyl peptidase 4 (DPP4) for potential use in the treatment of type 2 diabetes.<br>References Sutton, J., et al.: Bioorg. Med. Chem. Lett., 22, 1464 (2012); Lai, Z., et al.: Eur. J. Med. Chem., 83, 547 (2014)<br></p>

<p>Applications Important compounds in coffee aroma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Very Hygroscopic<br>Applications A component of elastin. It can be measured in all body fluids as biomarkers for in vivo degradation of matrix tissue elastin in man and animals.<br>References Sato, F., et al.: Clin. Biochem., 39, 746 (2006), Koenders, M., et al.: J. Pathol., 218, 446 (2009), Ma, S. et al.: J. Chrom. Anal. Tech. Biomed. Life Sci., 879, 1893 (2011),<br></p>

<p>Stability Hygroscopic<br>Applications Chlorobutanol is used as a preservative and sedative. It has also been shown to exhibit antibacterial properties.<br>References Dutta, T., et al.: PCT Int. Appl., 22, (2020); Ibibia, E., et al.: Asian. J. Pharm. Clin. Res., 9, 179-182 (2016)<br></p>

<p>Applications 2-Methylbutyrylglycine is one of the acylglycines, an important class of metabolites that have been used in the diagnosis of several “inborn errors of metabolism” (IEM).<br>References Costa, C., et al.: J. Pharmaceut. Biomed. Anal., 21, 1215 (2000), Garcia-Villoria, J., et al.: Clin. Biochem., 42, 2 (2009), Scalbert, A., et al.: Metabolomics, 5, 435 (2009),<br></p>

<p>Applications 1-Boc-4-(6-aminopyridin-3-yl)piperazine is used to prepare pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of cyclin-dependent kinases 4 and 6.<br>References Toogood, P., et al.: J. Med. Chem., 48, 2388 (2005); Cho, Y., et al.: J. Med. Chem., 53, 7938 (2010)<br></p>

<p>Stability Moisture sensitive<br>Applications Hexahydro-4-methylphthalic Anhydride, can be used in the mixture of other isomers nanofiber supported 3D interconnected BN nanosheets for epoxy nanocomposites with ultrahigh thermal management capability<br>References Chen, J., et al.: Adv. Funct. Material., 27, 5 (2017)<br></p>

<p>Applications A reagent used to synthesize 5-HT2A and 5-HT3 receptor ligands for use in treating CNS-related disorders.<br>References Bermudez, J., et al.: J. Med. Chem., 33, 1924 (1990),<br></p>

<p>Impurity Cefalexin EP Impurity D<br>Applications 3-Hydroxy-4-methyl-2(5H)-thiophenone (Cefalexin EP Impurity D) is an acid degradation product of Cephalexin (C256800) and Cefaclor (C235250), antibiotics.<br>References Dinner, A.: J. Med. Chem. 20, 963 (1977); Baetschi, S.W., et. al.: J. Pharmaceut., Sci., 86, 526 (1997)<br></p>

<p>Applications alpha-Methylene-gamma-valerolactone (cas# 62873-16-9) is a useful research chemical.<br></p>

<p>Applications 2-Methoxy-4-nitroaniline is a derivative of 4-Nitroaniline (N491770), which is used in the synthesis of photorefractive polymers, as novel chromophores in analytical study. As well, due to the absorption spectrum associated with 4-Nitroaniline, it is used to determine catechol derivatives in syntheses.<br>References Nagaraja, P. et al.: J. Pharm. Biomed. Anal., 25, 417 (2001);<br></p>

<p>Applications Glycyl-D-phenylalanine (cas# 34258-14-5) is a useful research chemical.<br></p>

<p>Applications 3-Ethyl-5-(2-hydroxyethyl)-4-methylthiazolium bromide is used in the novel synthesis of benzoin catalyzed by thiazolium salts.<br></p>