Amino Acids (AA)

Applications An intermediate in the production of Guanidinoacetic Acid
References Kennelly, P., et al.: J. Mol. Biol., 145, 583 (1981),

Applications Boc-D-serine is D-serine (S270975) with amine protected from eletrophiles by tert-butyloxycarbonyl group in organic synthesis. Boc-D-serine can be used to synthesize acetamido-methoxypropionamides such as Desacetyl Desmethyl Lacosamide (D288325) which is a potent anticonvulsant.
References Letiran, A., et al.: J. Med. Chem., 45, 4762 (2002); Wadavrao, S., et al.: Synthesis, 45, 3383 (2013)

Applications DL-Phenylalanine-2-13C (CAS# 64193-01-7) is a useful isotopically labeled research compound.

Applications 1-Bromo-3-methyl-2-butanol, can be used for preparation and polymerization of racemic isopropylthiirane.
References Dumas, Ph., et al.: Sciences Chimiques, 277, 939 (1973);

Applications 4-Methoxy-N-phenylaniline is a metabolite found from pears and apples.
References Pico, Y., et. al. Talanta, 81, 281 (2010)

Applications 4-Methoxy-2-pyridinecarboxylic Acid is an intermediate to prepare diacid analogs as glycogen phosphorylase inhibitors. It is also used to prepare allyl phenylethyl ether via ruthenium-pyridinecarboxylic acid-catalyzed allylation.
References Lu, Z., et al.: Bioorg. Med. Chem. Lett., 13, 4125 (2003); Tanaka, S., et al.: Chem. Lett., 38, 188 (2009)

Applications 4-methyl-3-nitrobenzoic acid (cas# 96-98-0) is a useful research chemical.

Applications O-Methyl Phosphorodichloridothioate-d3 is an intermediate used in the synthesis of Parathion-methyl-d6 (P192227), a derivative of Parathion (P192220), an organophosphate insecticide used on cotton, rice and fruit trees.
References Sykes, M., et al.: J. Agri. Food. Chem., 61, 4205 (2013); Sipes, N.S., et al.: Chem. Res. Toxicol., 26, 878 (2013);

Applications 6-Methyloctanoic acid is a branched fatty acid derivative found in ewe's milk and cheese. 6-Methyloctanoic acid is converted to lactones via antimycin biosynthetic pathways.
References Zviely, M.: Perfumer & Flavorist, 37, 30 (2012); Riclea, R.; et al.: ChemBioChem, 13, 1635 (2012).

Applications 1-(2-Methylphenyl)ethanamine (cas# 42142-17-6) is a useful compound for the synthesis and screening of macamides analogs as TNF-​α inhibitors.
References Perez, T., et al.: RSC Med. Chem., 11, 1196 (2020)

Applications D-Alanine-3,3,3-d3-N-t-BOC (CAS# 177614-70-9) is a useful isotopically labeled research compound.

Applications 5-Methylhexanol is an intermediate used in the synthesis of flavolipids as antitumor agents.
References Weaver, R., et al.: Bioorg. Med. Chem. Lett., 6, 2405 (1996), Guo, H., et al.: J. Med. Chem., 45, 2056 (2002), Hurley, L., et al.: Nat. Rev. Cancer, 2, 188 (2002),

Applications H-Lys(me)2-oh Hydrochloride

Applications 4-(dimethylamino)-7-methyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid hydrochloride (cas# 1432681-71-4) is a useful research chemical.

Applications 3-Methyl-6-nitroindazole a reactant used in the preparation of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Mei, Y. et al.: Let. Org. Chem., 9, 276 (2012); Harris, P. et al.: J. Med. Chem., 51, 4632 (2008); Olaussen, K., et al.: Oncogen., 28, 4249 (2009); Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009); Chan, A., et al.: Drugs, 69, 167 (2009)

Applications 2-(Methoxy-d3)-3-(2-methylpropyl)pyrazine is an intermediate used in the preparation of 2-methoxy-3-alkylpyrazines and their deuterated isotopologues.
References Schmarr, H. G., et al.: J. Label. Compds and Radiopharm., 54, 438 (2011); Gerritsma, D. A., et al.: J. Label. Compds. Radiopharm., 46, 243 (2003)

Applications N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide (cas# 129986-67-0) is a useful research chemical.

Applications DL-Phenyl-d5-alanine (CAS# 284664-89-7) is a useful isotopically labeled research compound.

Applications 2-Methyl-d3-3-butyn-1,1,1-d3-2-ol (CAS# 57444-27-6) is a useful isotopically labeled research compound.

Applications rac-threo-Methyl-13C, d3-phenidate Hydrochloride is the labeled analog of rac-threo-Methylphenidate Hydrochloride (M325671), which has shown that the pharmacological activity resides predominantly in the d-threo enantiomer.
References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961); Padmanabhan, G.R., et al.: Anal. Profiles Drug Subs., 10, 473 (1981); Kuczenski, R., et al.: J. Pharmacol. Exp. Ther., 296, 876 (2001), Pelham, W.E., et al.: J. Consult. Clin. Psychol., 61, 506 (1993); Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993)

Applications Intermediate in the production of Isosafrole and Ethylone.
References Katoch-Rouse, R., et al.: J. Med. Chem., 46, 642 (2003), Andrade, E., et al.: Chem. Biodivers., 5, 197 (2008),

Applications H-D-Phe-Homopro-Arg-pNA.2 Acetate is a useful organic reagent.

Applications N-Phenylglycinonitrile is a useful building block used in the preparation of purine derivatives with ability to inhibit protein kinases by competitive displacement of ATP.
References Laufer, S., et al.: J. Med. Chem.: 48, 710 (2005);

Applications Methyl 2-methyl-3-nitrobenzoate is used as a reagent to synthesize Lenalidomide (L328000). Lenalidomide is a compound that exhibits antimyeloma, anticancer and immunomodulatory activity and is used to treat patients with B-cell malignancies.
References Balaev, A., et al.: Pharm. Chem. J., 46, 676 (2013); Chanan-Khan, A. & Cheson, B.: J. Clin. Oncol., 26, 1544 (2008); Dredge, K., et al.: Microvasc. Res., 69, 56, 69 (2005); Palumbo, A., et al.: J. Clin. Oncol., 25, 4459 (2007)

Applications 4-ethyl-3-methyl-1H-pyrazol-5-amine (cas# 151521-79-8) is a useful research chemical.