Amino Acids (AA)

<p>1-[4-Methyl-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid is a reagent that is used as a complex compound, as a useful intermediate, and as a fine chemical. It has been used in the manufacture of pharmaceuticals, agrochemicals, dyes, and pigments. It also has many applications in research such as its use as a building block for organic synthesis or to synthesize other compounds with potential uses in medicine.</p>

<p>5-Methylindole-3-acetic acid (5MI3A) is a molecule that has been shown to have antiproliferative properties in bladder cancer cells. 5MI3A binds to the receptor for GABA, which is an inhibitory neurotransmitter. It also inhibits the production of proinflammatory mediators and reactive oxygen species in cancer cells. 5MI3A has anticancer activity in prostate cancer cells and may act by inducing apoptosis and inhibiting cell proliferation. Consumption of 5MI3A may reduce the risk of cancer development by preventing DNA damage from carcinogens, suppressing inflammation, and regulating cell growth through its antagonistic properties.</p>

<p>3,4-Methylenedioxy propiophenone is a synthetic compound with a fatty acid chain. It has been shown to have potent activity against leishmania and has been used as an intermediate in the synthesis of other drugs. 3,4-Methylenedioxy propiophenone can be synthesized by acylation reactions with chloride and acetylcholinesterase inhibition. This product also has molecular docking properties, which have been analyzed using computational methods, such as profiling and profile analysis.</p>

<p>L-Methionine is a non-essential amino acid that belongs to the group of essential amino acids. It is a major constituent of proteins and is used in the metabolism of lipids, carbohydrates, and nucleic acids. Methionine is also involved in the synthesis of cysteine, which is an important antioxidant. L-Methionine can be found in many foods such as eggs, dairy products, fish, poultry, soybean products, peanuts, beans and seeds. Studies have shown that L-methionine has effects on liver function and may be useful for prevention or treatment of liver disorders such as primary sclerosing cholangitis (PSC). This compound also plays a role in the formation of body tissues and cells. L-Methionine has been shown to increase glutathione levels which are important for detoxification reactions and protection against oxidative stress. It also helps regulate calcium metabolism by reducing calcium absorption from food and increasing excretion via</p>

<p>DL-Proline is a biological molecule that has been shown to bind to the DNA binding domains of proteins. This binding can be seen with the crystal structures of DL-proline and protein. The reaction mechanism for DL-proline is as follows:<br><br>DL-Proline + Protein → Proline + Protein<br><br>The equilibrium constant for this reaction is 1.0 at 298 K. The pKa value for the amide group in DL-proline is 4.8, which means that it will react with water and form an amine group at physiological pH levels. DL-Proline has been shown to have metabolic disorders.</p>

<p>(Fluoro-Methylphosphoryl)Oxycyclohexane is an organophosphorus compound that acts as a nerve agent. It inhibits the enzyme acetylcholinesterase, which is responsible for breaking down acetylcholine, leading to excess cholinergic stimulation. This can cause excessive contraction of muscles or even death. The exposure to (Fluoro-Methylphosphoryl)Oxycyclohexane can be detected by analytical methods such as gas chromatography/mass spectrometry. Oximes are used in the reactivation of acetylcholinesterase and are effective in preventing neuronal death. They bind to the phosphonyl group in (Fluoro-Methylphosphoryl)Oxycyclohexane and prevent it from inhibiting the enzyme acetylcholinesterase.</p>

<p>1-(3,4-Methylenedioxyphenyl) 2-nitropropene (1-MPNP) is a phosphatase inhibitor that is active against gram-negative bacteria by inhibiting enterotoxins and chlamydia. 1-MPNP inhibits the activity of tyrosine phosphatases, which are enzymes that play a major role in bacterial virulence. 1-MPNP competitively inhibits the activity of tyrosine phosphatases and prevents them from catalyzing the hydrolysis of polyphosphate substrates. This inhibition leads to an accumulation of polyphosphates in the bacterial cell membrane, which disrupts its permeability and leads to cell death.</p>

<p>N,N'-Di-boc-(L)-cystine-dimethyl ester is a fine chemical that can be used as a versatile building block. It is a complex compound with CAS No. 77826-55-2 and can be used as a reagent or speciality chemical in research. This chemical is also useful for the synthesis of various compounds and has been proven to be an excellent scaffold for chemical reactions.</p>

<p>Antimicrobial cationic peptide; used for microscopy glass slides coating</p>

<p>Applications (Z)-Ethyl 2-((2S,4R,5S)-4,5-Dihydroxy-2-methoxydihydro-2H-pyran-3(4H)-ylidene)acetate-13C3 is a by-product intermediate in synthesizing Patulin-13C3 (P206502), a labelled Patulin (PAT). It is a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation of glutathione in Hep G2 cells. Antibiotic.<br>References Scott, P., et al.: J. Agric. Food Chem., 20, 450 (1972); Aden, D., et al.: Nature, 282, 615 (1979); Surralles, J., et al.: Mutat. Res., 341, 169 (1995); Alves, I., et al.: Mutagenesis, 15, 229 (2000); Liu, B., et al.: Toxicol. Appl. Pharmacol., 191, 255 (2003)<br></p>

<p>Applications Tetrahydro-5-methyl-2-furanol 2-Benzoate is an intermediate in synthesizing 2,3-Dihydro-2-methylfuran (D447355), which is a general reagent used in next generation of biofuels. Dihydrofuranyl derivative.<br>References Simmie, J. et al.: J. Phys Chem., 116, 4528 (2012);<br></p>

<p>Applications 5-Hydroxy-7-methoxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one-d3 is an intermediate for the synthesis of Alternariol Monomethyl Ether-d3 (A575771), labelled methyl este analog fo Alternariol. An alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing the rate of DNA strand breaks.<br>References Asam, S., et al.: J. Agric. Food Chem., 57, 5152 (2009); Fehr, M., et al.: Mol. Nut. Food Res., 53, 441 (2009); Tiemann, U., et al.: Toxicol. Lett., 186, 139 (2009)<br></p>

<p>Applications 3-Acetylthio-2-methylpropanoic Acid-d5 (cas# 1189969-31-0) is a compound useful in organic synthesis.<br></p>

<p>4-Chloro-2-methylbenzoic acid is a high quality chemical that is used as an intermediate in the preparation of other compounds. It belongs to the group of complex compounds and has CAS No. 7499-07-2. This reagent can be used to synthesize speciality chemicals, research chemicals, and versatile building blocks. 4-Chloro-2-methylbenzoic acid is also useful as a reaction component for the synthesis of fine chemicals, pharmaceuticals, and agrochemicals.</p>

<p>Please enquire for more information about 2-Chloro-N-cyclohexyl-N-phenylpropanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Chloro-N-(4-methoxyphenyl)propanamide (2CMPP) is an acetanilide with a chloro substituent. It is used in research and yields better results than 2-chlorobenzoyl chloride. Acetanilides are prepared by the catalytic reduction of nitrobenzenes or chlorobenzenes with sodium or potassium borohydride in the presence of water. The reaction is exothermic and produces a white solid, which can be purified by recrystallization or column chromatography. Preparative methods for acetanilides include reaction of phenols with acetic anhydride and formaldehyde, followed by hydrolysis of the resulting ester to yield the corresponding amide.</p>

<p>Applications 3-((2-Chlorothiazol-5-yl)methyl)-5-methyl-1,3,5-oxadiazinan-4-imine Hydrochloride is an intermediate for the synthesis of N-(3-((2-Chlorothiazol-5-yl)methyl)-5-methyl-1,3,5-oxadiazinan-4-ylidene)benzenesulfonamide (C385860), which is an impurity of Thiamethoxam (T344180), a neonicotinoid insecticide.<br>References Oliver, J., et al.: J. Environ. Horticult., 28, 135 (2010), Ghosh, A., et al.: J. Entomol. Res., 34, 35 (2010), Chem. and Eng. News 90: 10 (2012)<br></p>

<p>Applications N-Methyl-d3-N-nitroso-p-toluenesulfonamide is the labeled version of Diazald; Diazomethane precursor.<br>References Takizawa, et al.: J. Pharm. Soc. Jpn., 70, 490 (1950)<br></p>

<p>Applications 2-(1-Cyano-1-methylethyl)azocarboxamide, cna be used in the synthesis of azobenzene side chain polymers derived from the bifunctional fumaric acid and itaconic acid.<br>References Kim, s. et al.: Polymer, Vol 55. P: 871-877 (2014);<br></p>

<p>Applications N,N-[Iminobis(trimethylene)]bis-D-gluconamide (cas# 86303-20-0) is a compound useful in organic synthesis.<br></p>

<p>4-Chloro-2-(methyl-phenyl-sulfamoyl)-benzoic acid methylester is an industrial chemical that is used in the production of other chemicals. It can be produced by the esterification of 4-chlorophenylacetic acid with methyl phenyl sulfonyl chloride, followed by diazotization and chlorination. This chemical also has the ability to form a condensation product with hydrazine.</p>

<p>Please enquire for more information about 6-Methoxy-1,2,3,4-tetrahydronaphthalen-2-ylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about L-(-)-Glyceraldehyde - Technical grade aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-[(4-Methyl-1H-pyrazol-1-yl)methyl]piperidine dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methylpentanoic acid is a fatty acid that is the product of anaerobic fermentation in the colon and can be found as an end product in the body. It can be used as a substrate in film tests for detecting bacteria, such as Escherichia coli, which are associated with bowel diseases. 4-Methylpentanoic acid has been shown to have inhibitory effects against nuclear dna replication, mitochondrial membrane potential, and energy metabolism. 4-Methylpentanoic acid also has antiinflammatory properties and has been shown to decrease body mass index. The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is an antituberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription</p>

<p>2-Bromo-6-methoxypyridin-3-amine is a perovskite that has been shown to have a high photoluminescence quantum yield and can be used in solar cells. This compound interacts with both the ligands and the acceptors, boosting the efficiency of these compounds. The 2-bromo-6 methoxypyridin-3 amine is a semiconductor with an electron affinity of 1.9 eV and a band gap of 1.6 eV. It has been shown to be efficient as a photoluminescent material in nanocrystals.</p>

<p>1,1-Dichloro-1-fluoro-methanesulfenylchloride is a hazardous chemical that belongs to the group of chlorine compounds. It has been used as an antibacterial agent in the past and has been shown to be effective against nematodes, helminths, and some microorganisms. It is also used as a solvent in the production of dyes and perfumes. 1,1-Dichloro-1-fluoro-methanesulfenylchloride is not active against bacteria that are resistant to sulfonic acids or amines.</p>

<p>Please enquire for more information about Methyl 5-chloro-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methoxy-N-methylbenzylamine is a synthesized compound that is structurally similar to piperazine. It has been synthesized using the Chloramine T method and has been shown to be active as an amine receptor ligand. This molecule binds to the amine receptor site of the GABAA receptor with high affinity, inhibiting chloride ion flow. The functional groups on this molecule are likely responsible for its binding activity. 4-Methoxy-N-methylbenzylamine may be useful in the treatment of scopolamine-induced amnesia, due to its ability to bind to specific receptors in the brain.</p>

<p>3,4-Methylenedioxyphenyl butyl ketone (MBK) is a synthetic drug that is structurally related to the amphetamines. MBK has been shown to induce locomotor hyperactivity in mice and exhibits pharmacokinetic properties similar to other amphetamine-type stimulants. MBK has a high affinity for the glutamate transporter, leading to an increase in extracellular concentrations of this neurotransmitter. This may lead to neurotoxicity with repeated use. MBK also interacts with the glutamate receptor and affects glutamate homeostasis. The administration of ceftriaxone, a cephalosporin antibiotic, has been found to attenuate the effects of MBK on dopamine levels and motor activity in rats.</p>

<p>Please enquire for more information about 2-Methyl-4-(trifluoromethoxy)iodobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Diethoxy-methyl-thioxo-phosphorane is a chemical compound that is used in the manufacture of industrial chemicals. It has a vapor pressure of 0.0014 mmHg at 25°C, and can be quantified by chemical ionization with gas chromatography/mass spectrometry. Diethoxy-methyl-thioxo-phosphorane reacts with radiation to produce reactive oxygen species and other free radicals, which can damage DNA and cause cancer. The reaction rate is rapid, with an analogy to humans being exposed to nitrate compounds. Diethoxy-methyl-thioxo-phosphorane is also used in devices such as radiators and heaters, where it causes damage when combined with nitrates.</p>

<p>Please enquire for more information about (Ala31, Aib 32)-Neuropeptide Y (porcine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Iodo-L-tyrosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Angiotensin I/II (3-8) H-Val-Tyr-Ile-His-Pro-Phe-OH is a peptide that has physiological effects and is used as a drug. It is an active analogue of the peptide hormone angiotensin II, which regulates blood pressure and fluid volume. Angiotensin I/II (3-8) H-Val-Tyr-Ile-His-Pro-Phe-OH binds to angiotensin receptors and stimulates the release of calcium ions from cytosolic stores in cells, leading to increased muscle contractions and vasoconstriction. This drug may also have effects on dopamine levels in the brain, locomotor activity, and biochemical properties such as enzyme activity or protein binding.br&gt;<br>Angiotensin I/II (3-8) H-Val-Tyr-Ile-His Pro Phe OH has been shown to reduce the level of dopamine</p>

<p>Please enquire for more information about Ovalbumin (257-264) (chicken) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about H-Gly-Trp-Gly-Gly-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Fmoc-α-Me-Ser(tBu)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>