Amino Acids (AA)

<p>Applications 7-(2-Butyn-1-yl)-3,7-dihydro-3-methyl-1H-purine-2,6-dione is a reagent used in the preparation of pharmaceuticals for the treatment of fatty liver diseases.<br>References Muramoto, K. PCT Int. Appl. (2005), WO 2005053695 A1 20050616.<br></p>

<p>Applications An intermediate for the synthesis of Atazanavir and the preparation of some peptide analogs.<br>References Martin, J., et al.: Prog. Med. Chem., 32, 239 (1995), Bold, G., et al.: J. Med. Chem., 41, 3387 (1998).<br></p>

<p>Applications N,N'-1,2-Ethanediylbis[N-methy-β-alanine Diethyl Ester is an intermediate in the synthesis of penta- and hexacoordinated organotin compounds.<br>References Jurkschat, K., et al.: J. Organometallic. Chem., 347, 41 (1988);<br></p>

<p>Applications Intermediate for the preparation of Isotope Labelled Valdecoxib.<br></p>

<p>Applications (αZ)-α-(Methoxyimino)-2-methylbenzeneacetic-d7 Acid Methyl Ester is an intermediate used in the synthesis of Trifloxystrobin-d6 (T778902), which is the labelled analogue of Trifloxystrobin, a broad-spectrum foliar fungicide used in plant pritection. Trifloxystrobin functions by inhibiting fungal spore germination. Cannabis testing.<br>References Margot, P. et al.: Bright. Crop Prot. Conf. Pest Dis., 2, 375 (1998); Karadimos, D.A. et al.: Crop Prot., 24, 23 (2005); Prom, L.K. et al.: Plant Dis., 87, 252 (2003);<br></p>

<p>Applications DL-2-Methylbutyric Acid is a common chemical reagent used in the synthesis of anticancer naphthoquinione aliphatic amides. Also used in the synthesis of novel erythromycins.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kongkathip, B. et al.: Eur. J. Med. Chem., 60, 271 (2013); Pacey, M. et al.: J. Antibio. 51, 1029 (1998);<br></p>

<p>Applications Glycine-13C2,15N p-Toluenesulfonate is a by-product of an intermediate during the synthesis of m-Hydroxyhippuric Acid-13C2, 15N (H943127), a labelled m-Hydroxyhippuric Acid (H943125) which is a metabolite of caffeic and chlorogenic acids in human.<br>References Booth, A., et al.: J. Biol. Chem., 229, 51 (1957); Gonthier, M., et al.: Biomed. Pharmacother., 60, 536 (2006)<br></p>

<p>Applications A novel heterobifunctional linker for facile access to bioconjugates.<br>References Gait, M., et al.: Cell Mol. Life Sci., 60, 844 (2003), Hossany, R., et al.: Bioorg. Med. Chem., 12, 3743 (2004), Maurel, F., et al.: Bioorg. Med. Chem., 15, 5084 (2005),<br></p>

<p>Applications 1-Methoxy-4-(2-methyl-2-nitropropyl)benzene-d3 is an isotope labelled substituent in the synthesis of Olodaterol (O262000), a novel inhaled β2-adrenoceptor agonist with a 24h bronchodilatory efficacy.<br>References Bouyssou, T., et al.: Bioorg. Med. Chem. Lett., 20, 1410 (2010);<br></p>

<p>Stability Smelly, Air Sensitive<br>Applications 4-Methylbenzenethiol is used as a reactant in the preparation of sulfides by palladium-catalyzed coupling with aryl halides or sulfonates in presence of Josiphos ligand.<br>References Fernandez-Rodriguez, M., et al.: J. Am. Chem. Soc., 128, 2180 (2006);<br></p>

<p>Applications 3,8-Dinitro-6-phenyl-phenanthridine (cas# 82921-86-6) is a compound useful in organic synthesis.<br></p>

<p>Applications N-[4-[[3-(4-Hydroxy-3-methoxyphenyl)-1-oxo-2-propen-1-yl]amino]butyl]carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of Feruloylputrescine (F308950), an effector of plant root systems, influencing development of nutrient gathering root systems.<br>References Ben-Hayyim G. et al.: FEBS Lett., 4, 145 (1994);<br></p>

<p>Applications 3-Methoxycarbonyl-1-(methyl-d3)pyridinium Iodide (cas# 131448-16-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 3-(4-Fluorophenyl)-2-(2-methylpropionyl)propenoate-d6 (cas# 1185241-64-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-(5-((2-Chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic Acid Ethyl Ester is an intermediate in synthesizing Deschloroethyl Bendamustine Hydrochloride (D288365), which is an impurity formed from the synthesis of Bendamustine (B132500).<br>References Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996); Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001);<br></p>

<p>Applications A deuterated intermediate in the synthesis of Carisoprodol.<br></p>

<p>Applications 1,1'-[1,2-Ethanediylbis(oxy)]bis[5-methyl-2-nitro-benzene] is an intermediate in they synthesis of 5-Methyl-bis-(2-aminophenoxymethylene)-N,N,N’,N’-tetraacetate Methyl Ester<br></p>

<p>Stability Volatile<br>Applications 2-Methyl-2-butene is a trisubstituted olefin that is thought to be one of the prominent volatile compounds in exhaled human breath, possibly indicating the presence of lung cancer. 2-Methyl-2-butene is also used as a substitute for Methylene chloride as a dental softening agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Asmussen, E. &amp; Peutzfeldt, A.: Eur. J. Oral Sci., 108, 335 (2000); Bajtarevic, A., et al.: BMC Cancer, 9, No pp. given (2009); Buriak, J. &amp; Allen, M.: J. Am. Chem. Soc., 120, 1339 (1998); Goto, S., et al.: Can. J. Chem. Eng., 71, 821 (1993)<br></p>

<p>Applications 1-(3-Hydroxy-4-methylphenyl)-1-propanone is an intermediate in the synthesis of 3-Hydroxy Tolperisone Maleate which is a metabolite of Tolperisone (T535475).<br>References Shiozawa, A., et al.: Eur. J. Med. Chem. Chim. Ther., 30, 85 (1995),<br></p>

<p>Applications N-Methyl-6-(4-nitrophenoxy)-4-pyrimidinamine is an intermediate in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.<br>References Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);<br></p>