Amino Acids (AA)

Applications 4-Formyl-2-methylresorcinol is a reactant in the synthesis of 3-benzo[b]thiophenecoumarin, with potent anti-proliferative activity against breast cancer cell lines
References Zhao, H., et. al.: ACS Med. Chem., Lett., 3, 327 (2012)

Impurity Rivastigmine EP Impurity H
Applications 3'-Methoxyacetophenone (Rivastigmine EP Impurity H) is a general reactant/reagent used in the synthesis of potent inhibitors targetting the drug-resistant mutant of Influenza A Virus. As well, used in the preparation of VEGFR-2 inhibitors and anticancer agents.
References Abou-Seri, S. et al.: Eur. J. Med. Chem., 107, 165 (2016); Li, F. et al.: J. Med. Chem., 59, 1207 (2016);

Applications 2-Amino-5-methyl-pyrimidin-4-ol is a useful reagent for the preparation of pyrimidines.
References Von, A. S., et al.: Science of Synthesis, 16, 379 (2004)

Applications 4-(1,1-Dimethylethyl)-2-(1-methylpropyl)-6-[2-(2-nitrophenyl)diazenyl]phenol is an intermediate in the synthesis of 2-(2H-Benzotriazol-2-yl)-4-(tert-butyl)-6-(sec-butyl)phenol (B206645), which is often used to increase product stability and to prevent discolouration in various consumer and industrial goods such as plastics. Benzotriazole UV stabilizers, such as 2-(2H-Benzotriazol-2-yl)-4-(tert-butyl)-6-(sec-butyl)pheno, are pollutants for the aquatic environment and have been implicated as a potential stable and toxic ligands for the aryl hydrocarbon receptor in human.
References Liu, R., et al.: Talanta 120, 158 (2014); Nagayoshi, H., et al.: Environ Sci Technol. 49, 578 (2015).

Applications 6-Methoxy-1,2,3,4-tetrahydroisoquinoline is used in the synthesis of novel spirobicyclic Artemisinin (A777500) analogues for anti-tumor activity.
References Liu, G. et al.: Eur. J. Med. Chem., 103, 17 (2015);

Applications 5,6-Difluoro-2-Hydrazino-1-Methyl-1H-benzimidazole is an intermediate used in the preparation of pentacyclic fluoroquinolines.
References Nosova, E. V., et al.: Russian J. Org. Chem., 34, 408 (1998)

Applications 1H-1,2,3-Triazole-5-methanamine Dihydrochloride is used in the preparation of optimized 5-membered heterocycle-linked pterins for inhibition of ricin toxin A. Also used in the synthesis of orally bioavailiable human neurokinin-1 (hNK1) antagonists.
References Lin, P. et al.: Bioorg. Med. Chem. Lett., 17, 5191 (2007); Pruet, J. et al.: ACS Med. Chem. Lett., 3, 588 (2012);

Applications N-Benzoylglycine-2,2-d2 (CAS# 208928-78-3) is a useful isotopically labeled research compound.

Applications N-Benzyl-N-methylpentan-1-amine is a useful intermediate for organic synthesis and other chemical processes.
References Buck, J. S., et al.: J. Am. Chem. Soc., 63, 1964 (1941), Poling, S. M., et al.: Phytochemistry, 21, 601 (1982)

Applications 6-chloro-2-methyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione (cas# 129689-05-0) is a useful research chemical.