Amino Acids (AA)

Stability Very Hygroscopic
Applications 1-O-Dimethoxytrityl-2-(N-Fmoc)-4-Aminobutyl)-1,3-propanediol is a useful reagent for the synthesis of acridine and​/or lipid containing oligodeoxyribonucleotides.
References Marasco, C. J., et al.: Tetra. Lett., 35, 3029 (1994)

Applications A labelled metabolite of Toluene.
References Gargas, M., et al.: Toxicol. Appl. Pharmacol., 98, 87 (1989), Commandeur, J., et al.: Pharmacol. Rev., 47(2), 271 (1995), Campo, P., et al.: Neurotoxicol. Teratol., 21, 427 (1999), Lohse, C., et al.: J. Agr. Food Chem., 48, 5913 (2000),

Stability Hygroscopic
Applications (S)-(+)-2-Methylbutyric Acid is a chiral starting reagent used in various synthetic preparations.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Neves, F., et al.: Beilstein. J. Org. Chem., 7, 1504 (2011); King, A.M., et al.: J. Medn. Chem., 54, 6432 (2011); Ferrarni, A., et al.: Chirality., 26, 9 (2011);

Stability Hygroscopic
Applications 4-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride (cas# 106261-49-8) is a compound useful in organic synthesis.

Applications Thiodiglycolic Acid-d4 acts as a reagent for the synthesis of metabolites of S-carboxymethyl-L-cysteine and S-methyl-L-Cysteine and of some isotoically labelled (2H, 13C) analogs.
References Meese, C. O., et al.: Archiv der Pharmazie, 323, 957 (1990)

Applications N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.
References Sanchez-Lopez, E., et al.: J. Pharm. Biomed. Anal., 140, 313 (2017)

Applications Useful in the study of tyrosine-phosphorylation, which has been linked with the malignant transformation of cells by some RNA tumour viruses.
References Sefton, B.M., et al.: Cell, 20, 807 (1980), Erikson, R., et al.: Perspect. Virol., 11, 93 (1981), Lee, E-S, et al.: J. Org. Chem., 59, 2086 (1994)

Applications Carbamoyl-guanidine Amidino Urea Salt, Hydrochloride salt (cas# 926-72-7) is a compound useful in organic synthesis.

Applications L-Arginine-2,3,3,4,4,5,5-d7 HCl (CAS# 204244-77-9) is a useful isotopically labeled research compound. It can be used with Raman scattering for imaging living cells and organisms.
References Min, W., et al., PCT Int. Appl. (2014), WO 2014205074 A2

Stability Very Hygroscopic
Applications Hydroxyisovaleroyl Carnitine is used as a diagnostic tool to identify the presence of orofacial clefts. Also used in the screening and diagnostics of inborn errors of metabolism.
References Denes, J. et al.: Anal. Chem., 84, 10113 (2012); Budner, M. et al.: Arch. Oral. Biol., 58, 459 (2013);

Applications L-2-Aminobutyric Acid-d6 is the isotope labelled analog of L-2-Aminobutyric Acid (A602930); a receptor antagonist.
References Porter, D.J.T., et al.: Biochem. Pharmacol., 50, 1475 (1995)

Applications N-(1H-pyrrol-2-ylcarbonyl)-Glycine has been used as a diagnostic marker of hyperprolinemia type II.
References Walker, V., et al.: Clinica Chimica Acta, 405, 153 (2009).

Applications L-Theanine-d5 (N-ethyl-d5) (CAS# 1217451-85-8) is the labelled version of L-Theanine (T340500(P)), which is a non-protein amino acid mainly found naturally in the green tea plant. It may have activity in modulating the metabolism of cancer chemotherapeutics agents.
References Yokohoshi, H., et al.: Neurochem Res., 23, 667 (1998), Sugiyama, T., et al.: Clin Cancer Res., 5, 413 (1999)

Applications Caerulein is a ten amino acid oligopeptide that stimulates smooth muscle and increases digestive secretions. It is similar in action and composition to cholecystokinin. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction. It is used to induce pancreatitis in experimental animal models.
References Anastasi,E., et al.: Ep., 23, 699 (1997); De Caro, G., et al.: Br. J. Pharmac Chemother., 33, 48 (1968)

Stability Hygroscopic
Applications Lauryl Betaine is an amphoteric surfactant derived from N-dodecyl-N,N-dialkanol amine with protein denaturing potency. Lauryl Betaine is mainly used in shampoo, personal hygiene products and oil field chemicals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kimura, Y. et al.: J. SCCJ, 29, 106 (1995); Qin, C. et al.: GUang. Huag., 34, 30 (2006); Peng, Z. et al.: Riy. HUax. Gong., 37, 135 (2007);

Applications (±)-3-Amino-iso-butyric-2,3,3-d3 Acid is the labeled version of DL-3-Aminoisobutyric Acid (A603043(P)), which is a useful compound for suppressing atherosclerosis in apolipoprotein E-knockout mouse.
References Shimba, Y., et al.: Bio. Pharma. Bull., 43, 1016 (2020)

Applications Labelled DL-Serine is used in the synthesis of novel tryptoline derivatives as IDO (indoleamine 2,3-Deoxygenase) inhibitors, for potential use in Alzheimer’s treatment.
References Tanaka, M. et al.: Bioorg. Med. Chem., 21, 1159 (2013);

Applications Isotope labelled Intermediate for transsulfuration whereby a mammal transfers the sulfur of methionine via homocysteine to cysteine.
References Thompson, J.W., et al.: J. Biol. Chem., 266, 17011 (1991), Yoshida, Y., et al.: Microbiol., 148, 3961 (2002), Jiracek, J., et al.: J. Med. Chem., 49, 3982 (2006),

Applications L-3-Benzothienylalanine

Applications L-Aspartic Acid is a non-essential amino acid found in food sources. L-Aspartic Acid is one of the 20 proteinogenic amino acids; the building blocks of proteins. Its conjugate base L-aspartate is an excitatory neurotransmitter in the central nervous system.
References Ager, D.J. et al.: J. Mol. Catal. Enzym., 11, 199 (2001); Velisek, J. et al.: Cze. J. Food. Sci., 24, 1 (2006); Nagahama, M. et al.: Cell Tiss. Res., 318, 483 (2004);

Stability Volatile
Applications 3-ETHYL-3-METHYLHEPTANE (cas# 17302-01-1) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N-Boc-propargylamine is used in the preparation of triazolobenzylidene-thiazolopyrimidines which act as CDC25 phosphatase inhibitors. Also used in the synthesis of β-glucan polysaccharide analogs.
References Duval, R. et al.: J. Comb. Chem., 11, 947 (2009); Tanaka, H. et al.: Tetrahedron Lett., 53, 4104 (2012);

Applications L-Leucic Acid is a reagent in the synthesis of cryptophycins based macrocyclic depsipeptides which are used as tubulin inhibitors.
References Kumar, A., et al.: Eur. J. Med. Chem., 93, 55 (2015)

Applications 2-Methylresorcinol (cas# 608-25-3) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Used in peptide synthesis.
References Flohr, S., et al.: Chem. Eur. J., 5, 669 (1999), Kadereit, D., et al.: ChemBioChem., 1, 144 (2000), Volkert, M., et al.: Biol. Chem., 382, 1133 (2001),

Applications It is used as labelled biomarker for metabolic age.
References Selmer, T., et al.: Eur. J. Biochem., 268, 1363 (2001), Connelly, J., et al.: Drug Metab. Dispos., 30, 1357 (2002), Lindon, J., et al.: Pharm. Res., 23, 1075 (2006), Monteagudo, E., et al.: Xenobiotica, 37, 1000 (2007),

Applications A naturally occurring nitrostable secondary amine found in tabacco smoke condensate.
References Singer, G.M. et al.: J. Agric. Food Chem. 24, 553(1976); Bush, L. P. et al.: Can. J. Plant Sci. 50, 289(1970).

Applications (2-methylphenoxy)acetic acid (cas# 1878-49-5) is a useful research chemical.

Stability Hygroscopic
Applications A metabolite of Melatonin (M215000).
References Reiter, R.J., et al.: J. Biomed. Sci., 7, 444 (2000), Chen, Z., et al.: Am. J. Physiol, 284, 1618 (2003), Barrenetxe, J., et al.: J. Physiol. Biochem., 60, 61 (2004),

Applications 5'-O-Methylthymidine (cas# 14504-60-0) is a useful research chemical.

Applications 7-Chloro-8-methylquinoline (cas# 78941-93-2) is a compound useful in organic synthesis.

Applications Used for colorimetric determination of peptidase activity in bacteria.

Applications Labelled 4-Methyl-2-oxovaleric Acid, an α-ketomonocarboxylic acid that triggers insulin release by acting upon receptor sites which differ from those occupied by amino acids. 4-Methyl-2-oxovaleric Acid is an intermediate in the metabolism of Leucine.
References Panten, U. et al.: Naun.-Schmied. Arch. Pharmacol., 291, 405 (1975); Vague, P. et al.: Diab. Metab., 1, 185 (1975); Francois, G. et al.: Lancet, 1, 858 (1984);

Stability Hygroscopic
Applications Dityrosine (DY), a tyrosine dimer formed by 3,3’-biaryl bond formation can be used as a biomarker to detect oxidative protein damage and selective proteolysis. Fluorescence intensity decays of Dityrosine are generally characterized by two decay components, one with a lifetime in the range of 150 to 800 ps and another between 2.5 and 4.5 ns.
References Libertini, L., et al.: Biophys. J., 47, 765 (1985), Huggins, T., et al.: J. Biol. Chem., 268, 12341 (1993), Malencik, D., et al.: Biochemistry, 35, 4375 (1996),

Applications L-Abrine is an indoleamino acid that displays radical scavenging and antioxidant properties.
References Yang, M., et al.: Food. Funct., 5, 2268 (2014);

Applications D-Arginine is an unnatural isomer of L-Arginine (A769505), and is used to inhibit glutamate-induced nitric oxide production in rats. Derivatives of D-Arginine are used for pharmaceutical purposes, one example is 1-Deamino-8-D-arginine vasopressin, which is used to treat various bleeding disorders.
References Castellano, M., et al.: Neurosci. Lett., 314, 127 (2001); Kobrinsky, N., et al.: Lancet, 323, 1145 (1984); Weyrich, A., et al.: Circulation, 86, 279 (1992)