Enzyme Substrates

<p>COX inhibitor; nonsteroidal anti-inflammatory drug</p>

<p>4-Aminoantipyrine has been used as an analgesic and anti-inflammatory agent. It can also target peroxidase enzymes to produce a red color</p>

<p>1,8,15,22-Tetrazacyclooctacosane-2,7,16,21-tetraone is an inhibitor with potent anticancer properties. It induces apoptosis in cancer cells by inhibiting kinases that are critical for cell survival and proliferation. This compound has been shown to be effective against various types of cancer in both Chinese hamster ovary and human cancer cell lines. Additionally, it has been found to increase the excretion of the anti-allergic drug rupatadine in urine. The use of 1,8,15,22-Tetrazacyclooctacosane-2,7,16,21-tetraone as a tumor inhibitor has also been investigated in combination with other kinase inhibitors such as bendamustine analogs. This compound holds great potential for the development of new anticancer therapies.</p>

<p>2,4-Dinitrophenyl)-L-lysine hydrochloride monohydrate is a lysine derivative that has been modified with a 2,4-dinitrophenyl group. It could be used as an enzyme substrate to monitor enzymes that recognize and modify lysine residues, such as lysine methyltransferases and demethylases, lysine acylases and lysine oxidases.</p>

<p>Fast Blue BB is commonly used for assaying beta-glycosidase activity and the chromogenic reaction between Fast Blue BB and beta-naphthol results in a reddish colored product and is at the basis of its application to different enzymatic activity assays. Produces a fluorescent, blue-green chromophore.</p>

<p>4-Nitrophenyl 2-azido-2-deoxy-beta-D-galactopyranoside is a chromogenic substrate for beta-galactosidase. Upon hydrolysis, para-nitrophenol is released yielding a yellowish colour. 4-Nitrophenyl 2-azido-2-deoxy-beta-D-galactopyranoside is used in different applications such as the Bacterial enzyme assays (e.g., E. coli detection)</p>

<p>Remazol Brilliant Blue R D-xylan is a chromogenic substrate used for the detection and quantification of xylanase enzyme activity. This substrate consists of a xylan polymer backbone covalently linked to the Remazol Brilliant Blue R dye. Upon cleavage by xylanase enzymes, the dye is released, producing a vibrant blue color that can be easily measured spectrophotometrically. This substrate is widely used in various applications, including the study of xylanase-producing microorganisms, optimization of enzyme production, and evaluation of enzyme kinetics.</p>

<p>4-Nitrophenyl 2-acetamido-2-deoxy-4-O-(β-D-galactopyranosyl)-α-D-glucopyranoside is a high-quality chromogenic pNP enzyme substrate specifically designed to enable effective and accurate detection of enzyme activity. By utilizing this advanced substrate, researchers and professionals can perform a range of applications, including activity assays, enzyme inhibition studies, and substrate specificity profiling. This substrate's unique properties result in exceptional sensitivity and throughput, ensuring effective results for a wide variety of enzyme assays.</p>

<p>Used for synthesis of chiral amines from ketones and ketoacids</p>

<p>Methyl 4-nitrophenyl hexylphosphonate is a phosphonate inhibitor of the enzyme serine esterase. It has been shown to be more potent than other irreversible inhibitors such as ethyl 4-nitrophenyl hexylphosphonate and methyl 4-nitrophenoxybutyl phosphate. This compound is an immobilized form of the methyl 4-nitrophenyl hexylphosphonate that is immobilized on an inert surface, such as silica gel, via a covalent bonding process. The immobilization of the molecule ensures that it will not leach from the surface and is stable over time. The molecular weight of this substance is 411.5 Daltons and its molecular formula is C8H15NO4P. This substance has a diameter of 0.8 nm and can be found in crystalline form with a melting point of 143 degrees Celsius at atmospheric pressure. Methyl 4-nitrophenyl</p>

<p>Please enquire for more information about 1,2,4-trihydroxynaphthalene-4-O-b-D-glucopyranoside including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>The photorelease of 2-deoxy-2-fluoro-L-fucose from 2-nitrobenzyl-2-deoxy-2-fluoro-L-fucopyranoside was performed under a 365 nm LED illumination. It has been shown in plant cells this liberated 2-deoxy-2-fluoro-L-fucose can be converted by the endogenous metabolic machinery into the corresponding nucleotide-sugar, which then efficiently inhibits Golgi-localized fucosyltransferases.</p>

<p>Please enquire for more information about 4-Nitrophenyl valerate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-O-(4-Nitrophenyl)-a-D-N-acetylneuraminic acid, also known as p-nitrophenyl N-acetylneuraminic acid, is a chromogenic substrate specifically designed for the detection and quantification of neuraminidase (sialidase) activity. Upon cleavage by neuraminidase, it releases a yellow-colored product, 4-nitrophenol, which can be easily monitored spectrophotometrically at 405 nm. This substrate is widely used in various applications, including enzyme kinetics studies, inhibitor screening, and the determination of neuraminidase activity in biological samples such as viruses, bacteria, and cell lysates. It is particularly useful for studying the enzymatic properties of neuraminidases from different sources and for the development of novel antiviral and antibacterial agents targeting neuraminidase activity.</p>

<p>Please enquire for more information about 1,2,4-trihydroxynaphthalene-2-O-b-D-glucopyranoside including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Nitrophenyl-myo-inositol-1-yl phosphate is a highly specific chromogenic substrate used for the detection, quantification, and characterization of phosphoinositide phosphatases. When cleaved by the target enzyme, it generates a highly absorbing 4-nitrophenyl moiety, producing a yellow color that can be measured spectrophotometrically. This versatile substrate is valuable in examining phosphoinositide phosphatase activity, enzyme kinetics, substrate specificity, and inhibition studies in various cellular processes, including signal transduction, lipid metabolism, and membrane trafficking.</p>

<p>Bioluminescent substrate for detection of E. coli.</p>

<p>Luciferin-beta-D-glucuronide, dipotassium salt is a fluorescent compound that is used as a diagnostic tool. It can be used to detect the presence of enzymes, such as beta-galactosidase and beta-glucuronidase, in culture media or biological fluids. Luciferin-beta-D-glucuronide, dipotassium salt is also used for food testing and environmental testing.</p>

<p>4-Nitrophenyl 2-acetamido-3,6-di-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-2-deoxy-a-D-galactopyranoside is a fluorogenic substrate that is used in enzyme assays to detect the presence of an enzyme. The substrate reacts with the enzyme to produce a fluorescent product. 4NPAAG can be used for diagnostics, culture media, food testing and environmental testing.</p>

<p>Please enquire for more information about H-Ala-Phe-Pro-pNA trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>