CAS 113507-06-5

Moxidectina

Descripción:

Moxidectina es un lactona macrocíclica semisintética que pertenece a la clase de compuestos conocidos como avermectinas, que se derivan de la fermentación de la bacteria Streptomyces avermitilis. Se utiliza principalmente como agente antiparasitario, particularmente en medicina veterinaria, para el tratamiento de diversas infecciones parasitarias en animales, incluyendo nematodos y ectoparásitos. Moxidectina exhibe un amplio espectro de actividad y es conocido por su prolongada duración de acción, lo que permite una dosificación menos frecuente en comparación con otros agentes antiparasitarios. El compuesto actúa uniéndose a los canales de cloruro activados por glutamato en el sistema nervioso de los parásitos, lo que lleva a la parálisis y muerte del organismo. Moxidectina se administra típicamente por vía oral o mediante inyección, y su farmacocinética se caracteriza por una buena absorción y distribución en los tejidos. Es importante señalar que, aunque Moxidectina es efectivo contra muchos parásitos, no es efectivo contra todos, y su uso debe ser guiado por recomendaciones veterinarias para garantizar la seguridad y eficacia.

Fórmula: C₃₇H₅₃NO₈

InChI: InChI=1/C37H53NO8/c1-21(2)14-25(6)33-26(7)31(38-42-8)19-36(46-33)18-29-17-28(45-36)13-12-23(4)15-22(3)10-9-11-27-20-43-34-32(39)24(5)16-30(35(40)44-29)37(27,34)41/h9-12,14,16,21-22,26,28-30,32-34,39,41H,13,15,17-20H2,1-8H3/b10-9+,23-12+,25-14+,27-11+,38-31-/t22-,26-,28+,29-,30-,32+,33+,34+,36-,37+/m0/s1

Clave InChI: InChIKey=YZBLFMPOMVTDJY-LSGXYNIPSA-N

SMILES: C(=C\C(C)C)(\C)/[C@H]1O[C@@]2(C[C@@]3(C[C@](O2)(C/C=C(\C)/C[C@@H](C)/C=C/C=C\4/[C@@]5(O)[C@](C(=O)O3)(C=C(C)[C@@H](O)[C@]5(OC4)[H])[H])[H])[H])C/C(=N\OC)/[C@@H]1C

Sinónimos:

• (2aE,4E,4'E,5'S,6R,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-4'-(methoxyimino)-5',6,8,19-tetramethyl-6'-[(2E)-4-methylpent-2-en-2-yl]-3',4',5',6,6',7,10,11,14,15,17a,20,20a,20b-tetradecahydro-2H,17H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-17-one
• (6R,23E,25S)-5-O-Demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)milbemycin B
• 23-Methoxime-LL-F 28249α
• 5-O-demethyl-28-deoxy-25-(1E)-1,3-dimethyl-1-butenyl-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
• Cl 301423
• Cydectin
• Equest
• Milbemycin B, 5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-6,28-epoxy-23-(methoxyimino)-, [6R,23E,25S(E)]-
• Milbemycin B, 5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-buten-1-yl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
• Milbemycin B, 5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-
• MilbemycinB
• Moxidextin
• ProHeart 6
• Proheart
• Quest
• Quest (parasiticide)
• Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran], milbemycin B deriv.
• Vetdectin Oral Drench
• Moxidectin@100 μg/mL in Acetonitrile
• [6R,23E,25S(E)]-5-O-DeMethyl-28-deoxy-25-(1,3-diMethyl-1-butenyl)-6,28-epoxy-23-(MethoxyiMino)MilbeMycin B
• Moxidectin powder CAS 113507-06-5 fiona
• Moxidectin Solution, 100ppm
• Moxidectin CRS
• Moxidectin
• (1R,4S,4'E,5'S,6R,6'S,8R,10E,13R,14E,16E,20R,21R,24S)-21,24-dihydroxy-4'-methoxyimino-5',11,13,22-tetramethyl-6'-[(E)-4-methylpent-2-en-2-yl]spiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
• milbemycin B
• Moxidectin, >=98%
• (2R,2a'E,2a1'S,4Z,4'E,5S,6S,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',20'-Dihydroxy-4-(methoxyimino)-5,6',8',19'-tetramethyl-6-((E)-4-methylpent-2-en-2-yl)-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one
• Milbemycin B,
• Moxidectin for system suitability CRS
• Milbemycin B,5-O-demethyl-28-deoxy-25-(1,3-dimethyl-1-buten-1-yl)-6,28-epoxy-23-(methoxyimino)-,(6R,23E,25S)-
• Moxidectin,MilbeMycin B,23-MethoxiMe-LL-F 28249α,Equest,ProHeart 6
• Moxidectin Solution in Methanol, 100μg/mL
• Moxdectin
• (6R,23E,25S)-5-O-DeMethyl-28-deoxy-25-[(1E)-1,3-diMethyl-1-buten-1-yl]-6,28-epoxy-23-(MethoxyiMino)
• Moxidectin HOUSE STANDARD

Moxidectin

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Pureza: >98.0%(N)

Forma y color: White to Almost white powder to crystal

Peso molecular: 639.83

Ref: 3B-M3136

MOXIDECTIN CRS

CAS: 113507-06-5

MOXIDECTIN CRS

Fórmula: C₃₇H₅₃NO₈

Forma y color: Added

Peso molecular: 639.8186

Ref: 41-Y0000772

Moxidectin

CAS: 113507-06-5

Moxidectin

Fórmula: C₃₇H₅₃NO₈

Pureza: 94.2%

Forma y color: Off-White

Peso molecular: 639.37712

Ref: 47-1109

MOXIDECTIN FOR SYSTEM SUITABILITY CRS

CAS: 113507-06-5

MOXIDECTIN FOR SYSTEM SUITABILITY CRS

Fórmula: C₃₇H₅₃NO₈

Forma y color: Powder

Peso molecular: 639.8186

Ref: 41-Y0000747

Moxidectin

CAS: 113507-06-5

Lactones, nesoi

Fórmula: C₃₇H₅₃NO₈

Forma y color: White Powder

Peso molecular: 639.37712

Ref: 45-1448559

Milbemycin B,5-O-demethyl-28-deoxy-25-[(1E)-1,3-dimethyl-1-butenyl]-6,28-epoxy-23-(methoxyimino)-, (6R,23E,25S)-

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Pureza: 98%

Forma y color: Solid

Peso molecular: 639.8186

Ref: IN-DA00HCQ4

Moxidectin

CAS: 113507-06-5

Moxidectin

Fórmula: C₃₇H₅₃NO₈

Pureza: 98%

Peso molecular: 639.82

Ref: 54-OR1030356

Moxidectin

CAS: 113507-06-5

Moxidectin (CL301423) is an anthelmintic for heartworm/intestinal worms in dogs, cats, horses, cattle, and sheep; oral/topical/injectable.

Fórmula: C₃₇H₅₃NO₈

Pureza: 97.38%

Forma y color: White Solid

Peso molecular: 639.82

Ref: TM-T1157

Moxidectin-d3

CAS: 113507-06-5

Fórmula: C₃₇H₅₀D₃NO₈

Peso molecular: 642.85

Ref: 4Z-M-591

Moxidectin

CAS: 113507-06-5

Moxidectin

Fórmula: C₃₇H₅₃NO₈

Pureza: ≥95%

Peso molecular: 639.82

Ref: 54-BUP13574

Moxidectin

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Pureza: ≥ 95.0%

Forma y color: White to off-white or yellow powder

Peso molecular: 639.82

Ref: 7W-GW5324

Moxidectin

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Forma y color: White To Off-White Solid

Peso molecular: 639.84

Ref: 4Z-M-592

LC PestiMix 2 10 µg/mL in Acetonitrile

Producto controlado

CAS: 101-42-8, 103361-09-7, 105512-06-9, 111479-05-1, 111988-49-9, 113507-06-5, 114311-32-9, 116714-46-6, 120116-88-3, 122-34-9, 13360-45-7, 134098-61-6, 134605-64-4, 135158-54-2, 139-40-2, 144550-36-7, 145701-23-1, 14816-18-3, 149979-41-9, 156052-68-5, 158062-67-0, 16118-49-3, 161326-34-7, 1634-78-2, 1646-87-3, 165252-70-0, 16655-82-6, 168316-95-8, 1746-81-2, 177406-68-7, 181587-01-9, 18691-97-9, 1912-26-1, 1967-16-4, 1982-47-4, 19937-59-8, 208465-21-8, 2163-69-1, 2164-08-1, 22248-79-9, 23947-60-6, 24151-93-7, 24307-26-4, 24691-76-7, 2631-40-5, 2655-14-3, 27218-04-8, 272451-65-7, 283594-90-1, 29104-30-1, 298-01-1, 298-02-2, 3060-89-7, 30614-22-3, 330-54-1, 33693-04-8, 34622-58-7, 34681-10-2, 34681-23-7, 361377-29-9, 374726-62-2, 3761-42-0, 3766-60-7, 3766-81-2, 37764-25-3, 3878-19-1, 39196-18-4, 4147-51-7, 500008-45-7, 5234-68-4, 53380-22-6, 55814-41-0, 57646-30-7, 58810-48-3, 62610-77-9, 64628-44-0, 64902-72-3, 66063-05-6, 66215-27-8, 66840-71-9, 68157-60-8, 71283-80-2, 71422-67-8, 72490-01-8, 73250-68-7, 74223-64-6, 76578-14-8, 79241-46-6, 79277-27-3, 81405-85-8, 81412-43-3, 82097-50-5, 82558-50-7, 83-79-4, 83055-99-6, 865318-97-4, 93-71-0, 935545-74-7, 94125-34-5, 94593-91-6, 950-10-7, 999-81-5

Forma y color: Mixture

Ref: 04-A50000802AL

Moxidectin

Producto controlado

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Forma y color: Neat

Peso molecular: 639.82

Ref: 04-CA15335000

Moxidectin 100 µg/mL in Acetonitrile

CAS: 113507-06-5

Fórmula: C₃₇H₅₃NO₈

Forma y color: Single Solution

Peso molecular: 639.82

Ref: 04-A15335000AL-100

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3, 113507-06-5, 115550-35-1, 117704-25-3, 119478-55-6, 122-11-2, 1220-83-3, 123997-26-2, 127-71-9, 127-79-7, 144-82-1, 144-83-2, 14698-29-4, 148-79-8, 149676-40-4, 155569-91-8, 19562-30-2, 20559-55-1, 2447-57-6, 28657-80-9, 31430-15-6, 31431-39-7, 389-08-2, 42835-25-6, 43210-67-9, 515-64-0, 51940-44-4, 53716-50-0, 54029-12-8, 54965-21-8, 57-67-0, 57-68-1, 58306-30-2, 59-40-5, 63-74-1, 651-06-9, 68-35-9, 68786-66-3, 70288-86-7, 70458-96-7, 71751-41-2, 72-14-0, 723-46-6, 729-99-7, 74011-58-8, 75184-71-3, 79660-72-3, 80-08-0, 80-32-0, 80-35-3, 80983-34-2, 82419-36-1, 85721-33-1, 88254-99-3, 91296-86-5, 91296-87-6, 93106-60-6, 948-71-0, 98079-52-8

Forma y color: Mixture

Ref: 04-K30000030

PharmaVetResiMix 1 Avermectins-v6 10 µg/mL in Methanol

Producto controlado

CAS: 113507-06-5, 117704-25-3, 123997-26-2, 155569-91-8, 70288-86-7, 71751-41-2

Forma y color: Mixture

Ref: 04-A30000031ME

Moxidectin

CAS: 113507-06-5

(2R,2a'E,2a1'S,4Z,4'E,5S,6S,6'R,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',20'-Dihydroxy-4-(methoxyimino)-5,6',8',19'-tetramethyl-6-((E)-4-methylpent-2-en-2-yl)-2a1',3,4,5,6,6',7',10',11',14',15',17a',20',20a'-tetradecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one

Fórmula: C₃₇H₅₃NO₈

Pureza: 98%

Peso molecular: 639.82

Ref: IN-DG140452

Moxidectin-d3

Producto controlado

CAS: 113507-06-5

Stability Light Sensitive
Applications Moxidectin-d3 is a the labelled form of Moxidectin (M744800). Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005)

Fórmula: C₃₇H₅₀D₃NO₈

Forma y color: Neat

Peso molecular: 642.84

Ref: TR-M744802

Moxidectin

CAS: 113507-06-5

Applications Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005);

Fórmula: C₃₇H₅₃NO₈

Forma y color: Neat

Peso molecular: 639.82

Ref: TR-M744800