EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 581 productos de "EGFR"
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AEE 788
CAS:Fórmula:C27H32N6Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:440.60Anti-EGFR Antibody (3B845)
Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.Forma y color:Odour Liquid(3S,4S)-PF-06459988
CAS:(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Fórmula:C19H22ClN7O3Forma y color:SolidPeso molecular:431.88Tucatinib hemiethanolate
CAS:Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.Fórmula:C54H54N16O5Pureza:99.76%Forma y color:SolidPeso molecular:1007.11Anti-Phospho-EGFR (Tyr1092) Antibody (9I899)
Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.Forma y color:Odour LiquidAnti-EGFR Antibody (7X976)
Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.Forma y color:Odour LiquidAnti-Phospho-EGFR (Tyr1068) Antibody (3Q245)
Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.Forma y color:Odour LiquidCanertinib
CAS:Fórmula:C24H25ClFN5O3Pureza:>98.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:485.94AV-412 free base
CAS:AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).Fórmula:C27H28ClFN6OForma y color:SolidPeso molecular:507Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:315.76Hypericin
CAS:Fórmula:C30H16O8Pureza:>95.0%(HPLC)Forma y color:Black powder to crystalPeso molecular:504.45Mavelertinib
CAS:Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.Fórmula:C18H22FN9O2Pureza:99.89%Forma y color:SolidPeso molecular:415.42EGFR Protein, Rhesus macaque, Recombinant (His)
EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.Forma y color:Lyophilized PowderPeso molecular:69.8 kDa (predicted). Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.Rilematovir
CAS:Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.Fórmula:C21H20ClF3N4O3SPureza:99.95%Forma y color:SolidPeso molecular:500.92Neratinib maleate
CAS:Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.Fórmula:C34H33ClN6O7Pureza:99.99%Forma y color:SolidPeso molecular:673.11Osimertinib dimesylate
CAS:Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).Fórmula:C30H41N7O8S2Pureza:98%Forma y color:SolidPeso molecular:691.82EGFR vIII Protein, Human, Recombinant (His)
EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Forma y color:Lyophilized PowderPeso molecular:61-75 Kda (reducing condition)Ref: TM-TMPJ-00648
1mg2.535,00€5µg90,00€10µg130,00€20µg193,00€50µg381,00€100µg600,00€200µg947,00€500µg1.765,00€EGFRVIII Protein, Human, Recombinant (His & Avi)
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.Tyrphostin RG 14620
CAS:Fórmula:C14H8Cl2N2Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:275.13EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.Forma y color:Lyophilized PowderPeso molecular:60-90 KDa (reducing condition)EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted)Ref: TM-TMPK-00689
5µg150,00€10µg242,00€20µg405,00€50µg794,00€100µg1.343,00€200µg1.978,00€500µg3.455,00€Rociletinib hydrobromide
CAS:Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).Fórmula:C27H29BrF3N7O3Pureza:98%Forma y color:SolidPeso molecular:636.46WHI-P180 Hydrochloride
CAS:Fórmula:C16H15N3O3·HClPureza:>97.0%(T)(HPLC)Forma y color:White to Light gray to Light yellow powder to crystalPeso molecular:333.77Erlotinib-d6
CAS:Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .Fórmula:C22H23N3O4Pureza:98%Forma y color:SolidPeso molecular:399.47EGFR Protein, Human, Recombinant (His & Avi)
EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.Flurandrenolide
CAS:Flurandrenolide is a corticosteroid with anti-inflammatory effects that activates EGFR (EC50=23 nM).Fórmula:C24H33FO6Forma y color:Crystals From Acetone + Hexane SolidPeso molecular:436.51Lapatinib Ditosylate
CAS:Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:925.46PD 158780
CAS:Fórmula:C14H12BrN5Pureza:>97.0%(HPLC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:330.19AG 1478 Hydrochloride
CAS:Fórmula:C16H14ClN3O2·HClPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:352.22Mubritinib
CAS:Fórmula:C25H23F3N4O2Pureza:>98.0%(HPLC)Forma y color:White to Gray to Brown powder to crystalPeso molecular:468.48Erlotinib
CAS:Fórmula:C22H23N3O4Pureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:393.44EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00427
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled
EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00425
5µg150,00€10µg242,00€20µg405,00€50µg794,00€100µg1.343,00€200µg1.978,00€500µg3.455,00€CL-387785
CAS:Fórmula:C18H13BrN4OPureza:>98.0%(GC)Forma y color:White to Light yellow powder to crystalPeso molecular:381.23Trichilinin D
CAS:Trichilinin D is a natural product that can be used in related research in the field of life sciences. Its product number is TN8637.Fórmula:C37H44O8Peso molecular:616.74WHI-P154
CAS:Fórmula:C16H14BrN3O3Pureza:>98.0%(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:376.21Daphnetin
CAS:Fórmula:C9H6O4Pureza:>90.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:178.14EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00690
5µg150,00€10µg242,00€20µg405,00€50µg794,00€100µg1.343,00€200µg1.978,00€500µg3.455,00€Anti-EGFR Monoclonal Antibody
Antibody Type: Rabbit Monoclonal
Application: FCM
Reactivity: HumanPureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaAnti-EGFR Monoclonal Antibody-Biotin
Antibody Type: Rabbit Monoclonal
Application: FCM
Reactivity: HumanPureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaTAS0728
CAS:TAS0728 is a HER2 inhibitor, with antitumor activityFórmula:C26H32N8O3Pureza:97.78%Forma y color:SolidPeso molecular:504.58Ref: TM-T7819
1mg48,00€5mg105,00€10mg166,00€25mg304,00€50mg485,00€100mg658,00€200mg888,00€1mL*10mM (DMSO)111,00€WHI-P154
CAS:WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Fórmula:C16H14BrN3O3Pureza:98% - 99.67%Forma y color:SolidPeso molecular:376.2ONO-7475
CAS:ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinaseFórmula:C32H26N4O6Pureza:98.74%Forma y color:SolidPeso molecular:562.57Tucatinib
CAS:Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).Fórmula:C26H24N8O2Pureza:99.05% - 99.96%Forma y color:SolidPeso molecular:480.52Ref: TM-T2364
1g1.071,00€2mg34,00€5mg50,00€10mg74,00€25mg117,00€50mg177,00€100mg333,00€500mg782,00€1mL*10mM (DMSO)82,00€Methyl 2,5-dihydroxycinnamate
CAS:Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.Fórmula:C10H10O4Pureza:99.60%Forma y color:CrystallinePeso molecular:194.18ZD-4190
CAS:ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.Fórmula:C19H16BrFN6O2Pureza:99.12%Forma y color:SolidPeso molecular:459.27Ref: TM-T5475
1mg80,00€5mg173,00€10mg261,00€25mg414,00€50mg567,00€100mg767,00€200mg1.018,00€1mL*10mM (DMSO)175,00€Mutant EGFR inhibitor
CAS:Selective, potent inhibitor for mutated EGFR: L858R, Exon19 deletion, T790M resistance mutants.Fórmula:C27H30ClN7O2Pureza:98% - 99.75%Forma y color:SolidPeso molecular:520.03Ref: TM-T2705
1mg34,00€2mg49,00€5mg75,00€10mg92,00€25mg165,00€50mg250,00€100mg359,00€500mgA consultar1mL*10mM (DMSO)99,00€HG-14-10-04
CAS:HG-14-10-04 is a potent and specific ALK inhibitor.Fórmula:C29H34ClN7OPureza:99.75% - >99.99%Forma y color:SolidPeso molecular:532.08Ref: TM-T4015
1mg49,00€5mg92,00€10mg152,00€25mg222,00€50mg289,00€100mg409,00€200mg590,00€1mL*10mM (DMSO)111,00€TX1-85-1
CAS:TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.Fórmula:C32H36N8O3Pureza:97.16% - 98.12%Forma y color:SolidPeso molecular:580.68Alflutinib
CAS:Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition.Fórmula:C28H31F3N8O2Pureza:99.87%Forma y color:SolidPeso molecular:568.59Ref: TM-T22254
1mg57,00€5mg120,00€10mg177,00€25mg356,00€50mg537,00€100mg707,00€200mg1.009,00€1mL*10mM (DMSO)152,00€WS6
CAS:WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Fórmula:C29H31F3N6O3Pureza:97.65% - 99.95%Forma y color:SolidPeso molecular:568.59Tuxobertinib
CAS:Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.Fórmula:C29H29ClN6O4Pureza:99.22%Forma y color:SolidPeso molecular:561.03Ref: TM-T9072
2mg38,00€5mg57,00€10mg90,00€25mg178,00€50mg334,00€100mg497,00€200mg712,00€1mL*10mM (DMSO)71,00€Naquotinib
CAS:Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFRFórmula:C30H42N8O3Pureza:97.49%Forma y color:SolidPeso molecular:562.71Olafertinib
CAS:Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.Fórmula:C29H28F2N6O2Pureza:98.62% - 99.706%Forma y color:SolidPeso molecular:530.57FIIN-3
CAS:FIIN-3 is an irreversible inhibitor of FGFR.Fórmula:C34H36Cl2N8O4Pureza:97.63% - 98.92%Forma y color:SolidPeso molecular:691.61WZ8040
CAS:WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).Fórmula:C24H25ClN6OSPureza:97.42% - 99.785%Forma y color:SolidPeso molecular:481.01ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Fórmula:C23H25NO·HClPureza:98.05%Forma y color:SolidPeso molecular:367.91SU5214
CAS:SU5214 is a modulator of tyrosine kinase signal transduction.Fórmula:C16H13NO2Pureza:99.45% - 99.55%Forma y color:SolidPeso molecular:251.28Chrysophanol
CAS:Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.Fórmula:C15H10O4Pureza:99.44% - 99.91%Forma y color:Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°CPeso molecular:254.24AG490
CAS:AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.Fórmula:C17H14N2O3Pureza:98.6% - 99.85%Forma y color:Yellow SolidPeso molecular:294.3SYR127063
CAS:SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.Fórmula:C23H20ClF3N4O3Pureza:98.57%Forma y color:SolidPeso molecular:492.88AZD8931 diFuMaric acid
CAS:AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).Fórmula:C31H33ClFN5O11Pureza:99.92%Forma y color:SolidPeso molecular:706.1Ref: TM-T8751
1mg58,00€5mg118,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)170,00€CP-724714
CAS:CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2
Fórmula:C27H27N5O3Pureza:97.1% - 98.82%Forma y color:SolidPeso molecular:469.54PF-6274484
CAS:PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.Fórmula:C18H14ClFN4O2Pureza:97.71%Forma y color:SolidPeso molecular:372.78Ref: TM-T22396
2mg38,00€5mg57,00€10mg96,00€25mg177,00€50mg333,00€100mg495,00€500mg1.071,00€1mL*10mM (DMSO)63,00€WS3
CAS:WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Fórmula:C28H30F3N7O3Pureza:97.93% - 99.94%Forma y color:SolidPeso molecular:569.58CL-387785
CAS:CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Fórmula:C18H13BrN4OPureza:99.56% - 99.62%Forma y color:SolidPeso molecular:381.23Tyrphostin B44, (+) enantiomer
CAS:Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)Fórmula:C18H16N2O3Pureza:97.18%Forma y color:SolidPeso molecular:308.33Ref: TM-T22450
1mg39,00€5mg82,00€10mg115,00€25mg192,00€50mg264,00€100mg380,00€200mg515,00€1mL*10mM (DMSO)90,00€lavendustin C
CAS:lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Fórmula:C14H13NO5Pureza:98.06%Forma y color:Yellow To Tan PowderPeso molecular:275.26Ref: TM-T4185
1mg42,00€2mg55,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€1mL*10mM (DMSO)90,00€Canertinib
CAS:Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing growth and hypoxia.Fórmula:C24H25ClFN5O3Pureza:98% - >99.99%Forma y color:White Or Similar To White Crystalline PowderPeso molecular:485.94AG-1557 hydrochloride (189290-58-2(free base))
AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).Fórmula:C16H15ClIN3O2Pureza:98.64%Forma y color:SolidPeso molecular:443.66Tyrphostin AG 879
CAS:Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.Fórmula:C18H24N2OSPureza:99.05%Forma y color:SolidPeso molecular:316.46Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14NS309
CAS:NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.Fórmula:C8H4Cl2N2O2Pureza:97.55%Forma y color:SolidPeso molecular:231.04Ref: TM-T4612
5mg54,00€10mg65,00€25mg113,00€50mg205,00€100mg305,00€200mg445,00€500mg712,00€1mL*10mM (DMSO)59,00€Cetuximab
CAS:Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM).Fórmula:C107H179N35O36S7Pureza:95 - 98.60%Forma y color:LiquidPeso molecular:145.54 kDaEndoxifen (Z-isomer)
CAS:Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.Fórmula:C25H27NO2Pureza:99.19% - 99.81%Forma y color:SolidPeso molecular:373.49Ref: TM-T2280
1mg34,00€5mg66,00€10mg88,00€25mg167,00€50mg259,00€100mg389,00€200mg563,00€1mL*10mM (DMSO)75,00€Mubritinib
CAS:Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Fórmula:C25H23F3N4O2Pureza:98.61% - 99.85%Forma y color:SolidPeso molecular:468.47Epitinib
CAS:Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).Fórmula:C24H26N6O2Forma y color:SolidPeso molecular:430.5AG1557
CAS:AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
Fórmula:C16H14IN3O2Pureza:98.61% - 99.23%Forma y color:SolidPeso molecular:407.21E-4031 dihydrochloride
CAS:E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Fórmula:C21H29Cl2N3O3SPureza:99.31% - 99.87%Forma y color:SolidPeso molecular:474.44Derazantinib dihydrochloride
CAS:Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.Fórmula:C29H31Cl2FN4OForma y color:SolidPeso molecular:541.49Tyrphostin AG 528
CAS:Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).Fórmula:C18H14N2O3Pureza:99.64%Forma y color:SolidPeso molecular:306.32AG 1406
CAS:AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.Fórmula:C16H18N2OPureza:98.12%Forma y color:SolidPeso molecular:254.33PD168393
CAS:PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Forma y color:SolidPeso molecular:369.22Ref: TM-T6932
1mg37,00€2mg50,00€5mg63,00€10mg94,00€25mg146,00€50mg210,00€100mg294,00€1mL*10mM (DMSO)52,00€NRC-2694
CAS:NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.Fórmula:C24H26N4O3Pureza:99.90%Forma y color:SolidPeso molecular:418.49Ref: TM-T16343
1mg56,00€5mg105,00€10mg170,00€25mg281,00€50mg371,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)116,00€Theliatinib
CAS:Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).Fórmula:C25H26N6O2Pureza:99.67%Forma y color:SolidPeso molecular:442.51(E)-AG 99
CAS:(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).Fórmula:C10H8N2O3Pureza:99.23%Forma y color:SolidPeso molecular:204.18JCN037
CAS:JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).Fórmula:C16H11BrFN3O2Pureza:99.5%Forma y color:SolidPeso molecular:376.18PKI-166 hydrochloride
CAS:EGFR-kinase inhibitor, IC50 0.7 nM, >3000x selective, cuts metastasis and angiogenesis in mice, antihypertensive, oral use.Fórmula:C20H19ClN4OForma y color:SolidPeso molecular:366.85SU 4313
CAS:SU 4313 is a bioactive chemical.Fórmula:C18H17NOPureza:99.51% - 99.89%Forma y color:SolidPeso molecular:263.33Ref: TM-T3568
1mg34,00€5mg66,00€10mg92,00€25mg167,00€50mg236,00€100mg353,00€200mg517,00€1mL*10mM (DMSO)73,00€EGFR/ErbB-2/ErbB-4 inhibitor-2
CAS:EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)Fórmula:C23H21N3O3Pureza:99.55%Forma y color:SolidPeso molecular:387.43Ref: TM-T21954
1mg50,00€5mg94,00€10mg140,00€25mg245,00€50mg369,00€100mg537,00€200mg712,00€1mL*10mM (DMSO)103,00€Oritinib mesylate
CAS:Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.Fórmula:C32H41N7O5SForma y color:SolidPeso molecular:635.78Theliatinib tartrate
CAS:Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.Fórmula:C29H32N6O8Forma y color:SolidPeso molecular:592.6AEE788
CAS:AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Fórmula:C27H32N6Pureza:98% - >99.99%Forma y color:SolidPeso molecular:440.58Ref: TM-T2116
2mg47,00€5mg70,00€10mg103,00€25mg188,00€50mg325,00€100mg490,00€500mg1.103,00€1mL*10mM (DMSO)77,00€WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Fórmula:C16H15N3O3Pureza:99.21%Forma y color:SolidPeso molecular:297.31NRC-2694 hydrochloride
CAS:NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.Fórmula:C24H27ClN4O3Forma y color:SolidPeso molecular:454.95Trastuzumab
CAS:Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.Pureza:97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Forma y color:LiquidPeso molecular:145.36 kDaSulforaphene
CAS:Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Fórmula:C6H9NOS2Pureza:97.55% - 99.67%Forma y color:Slightly Yellowish LiquidPeso molecular:175.27Ref: TM-TL0016
1mg34,00€2mg46,00€5mg66,00€10mg92,00€25mg167,00€50mg241,00€100mg359,00€200mg525,00€1mL*10mM (DMSO)65,00€SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFórmula:C17H15NO2Pureza:99.46%Forma y color:SolidPeso molecular:265.31PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Fórmula:C15H16ClN5Pureza:98% - 98.21%Forma y color:White SolidPeso molecular:301.77Ref: TM-T6266
2mg44,00€5mg65,00€10mg110,00€25mg178,00€50mg304,00€100mg482,00€200mg687,00€1mL*10mM (DMSO)71,00€Tyrphostin AG30
CAS:Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.Fórmula:C10H7NO4Pureza:99.02%Forma y color:SolidPeso molecular:205.17
