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EGFR

EGFR

Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.

Se han encontrado 572 productos de "EGFR"

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  • Anti-EGFR Antibody (7X976)


    <p>Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.</p>
    Forma y color:Odour Liquid
  • Anti-Phospho-EGFR (Tyr1092) Antibody (9I899)


    <p>Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.</p>
    Forma y color:Odour Liquid
  • Anti-EGFR Antibody (3B845)


    <p>Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.</p>
    Forma y color:Odour Liquid
  • Anti-EGFR Antibody (9S619)


    <p>Anti-EGFR Antibody (9S619) is an antibody targeting EGFR. Anti-EGFR Antibody (9S619) can be used in ELISA, IHC, FCM.</p>
    Forma y color:Odour Liquid
  • EGFR Protein, Rhesus macaque, Recombinant (His)


    <p>EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.</p>
    Forma y color:Lyophilized Powder
    Peso molecular:69.8 kDa (predicted). Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.
  • Rilematovir

    CAS:
    <p>Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.</p>
    Fórmula:C21H20ClF3N4O3S
    Pureza:99.82%
    Forma y color:Solid
    Peso molecular:500.92
  • Lapatinib Ditosylate

    CAS:
    Fórmula:C29H26ClFN4O4S·2C7H8O3S
    Pureza:>98.0%(T)(HPLC)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:925.46

    Ref: 3B-L0467

    1g
    87,00€
  • Neratinib maleate

    CAS:
    <p>Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.</p>
    Fórmula:C34H33ClN6O7
    Pureza:99.64%
    Forma y color:Solid
    Peso molecular:673.11
  • BMS-599626

    CAS:
    Fórmula:C27H27FN8O3
    Pureza:>98.0%(HPLC)
    Forma y color:White to Light yellow to Light orange powder to crystal
    Peso molecular:530.56

    Ref: 3B-B5520

    10mg
    225,00€
    50mg
    709,00€
  • Canertinib

    CAS:
    Fórmula:C24H25ClFN5O3
    Pureza:>98.0%(HPLC)(qNMR)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:485.94

    Ref: 3B-C3818

    25mg
    200,00€
  • Tyrphostin RG 13022

    CAS:
    Fórmula:C16H14N2O2
    Pureza:>98.0%(GC)
    Forma y color:White to Yellow to Green powder to crystal
    Peso molecular:266.30

    Ref: 3B-T3575

    25mg
    177,00€
    100mg
    518,00€
  • BI-4142

    CAS:
    <p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>
    Fórmula:C28H27N9O2
    Pureza:97.21% - 98.09%
    Forma y color:Solid
    Peso molecular:521.57
  • AEE 788

    CAS:
    Fórmula:C27H32N6
    Pureza:>98.0%(HPLC)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:440.60

    Ref: 3B-A3271

    5mg
    123,00€
    25mg
    411,00€
  • Vandetanib

    CAS:
    Fórmula:C22H24BrFN4O2
    Pureza:>98.0%(T)(HPLC)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:475.36

    Ref: 3B-V0199

    1g
    340,00€
    200mg
    103,00€
  • Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245)


    <p>Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.</p>
    Forma y color:Odour Liquid
  • WHI-P154

    CAS:
    Fórmula:C16H14BrN3O3
    Pureza:>98.0%(HPLC)
    Forma y color:White to Yellow to Orange powder to crystal
    Peso molecular:376.21

    Ref: 3B-W0013

    10mg
    70,00€
    50mg
    238,00€
  • Tucatinib hemiethanolate

    CAS:
    <p>Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.</p>
    Fórmula:C54H54N16O5
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:1007.11
  • Hypericin

    CAS:
    Fórmula:C30H16O8
    Pureza:>95.0%(HPLC)
    Forma y color:Black powder to crystal
    Peso molecular:504.45

    Ref: 3B-H1845

    25mg
    400,00€
  • WHI-P180 Hydrochloride

    CAS:
    Fórmula:C16H15N3O3·HCl
    Pureza:>97.0%(T)(HPLC)
    Forma y color:White to Light gray to Light yellow powder to crystal
    Peso molecular:333.77

    Ref: 3B-W0021

    25mg
    169,00€
  • Neratinib

    CAS:
    Fórmula:C30H29ClN6O3
    Pureza:>95.0%(T)(HPLC)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:557.05

    Ref: 3B-N1062

    100mg
    238,00€
  • Tyrphostin RG 14620

    CAS:
    Fórmula:C14H8Cl2N2
    Pureza:>98.0%(HPLC)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:275.13

    Ref: 3B-T3576

    25mg
    169,00€
    100mg
    547,00€
  • PD 158780

    CAS:
    Fórmula:C14H12BrN5
    Pureza:>97.0%(HPLC)
    Forma y color:White to Yellow to Green powder to crystal
    Peso molecular:330.19

    Ref: 3B-P2567

    10mg
    124,00€
    50mg
    407,00€
  • Tyrphostin AG 1478

    CAS:
    Fórmula:C16H14ClN3O2
    Pureza:>98.0%(HPLC)
    Forma y color:Light orange to Yellow to Green powder to crystal
    Peso molecular:315.76

    Ref: 3B-T2944

    25mg
    198,00€
  • EGFR vIII Protein, Human, Recombinant (hFc)


    <p>EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.</p>
    Forma y color:Lyophilized Powder
    Peso molecular:90-120 KDa (reducing condition)
  • EGFR Protein, Human, Recombinant (His & Avi)


    <p>EGFR Protein, Human, Recombinant (His &amp; Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>
    Forma y color:Lyophilized Powder
    Peso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.
  • EGFR Protein, Human, Recombinant (His & Avi), Biotinylated


    <p>EGFR Protein, Human, Recombinant (His &amp; Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>
    Forma y color:Lyophilized Powder
    Peso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.
  • Mubritinib

    CAS:
    Fórmula:C25H23F3N4O2
    Pureza:>98.0%(HPLC)
    Forma y color:White to Gray to Brown powder to crystal
    Peso molecular:468.48

    Ref: 3B-M3058

    25mg
    203,00€
    100mg
    661,00€
  • Erlotinib-d6

    CAS:
    <p>Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .</p>
    Fórmula:C22H23N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:399.47
  • EGFR vIII Protein, Human, Recombinant (His)


    <p>EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>
    Forma y color:Lyophilized Powder
    Peso molecular:61-75 Kda (reducing condition)
  • EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated


    <p>EGFR vIII Protein, Human, Recombinant (His &amp; Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.</p>
    Forma y color:Lyophilized Powder
    Peso molecular:60-90 KDa (reducing condition)
  • EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled


    <p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>
    Forma y color:Lyophilized Powder
    Peso molecular:41.6 kDa (predicted)
  • AV-412 free base

    CAS:
    <p>AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).</p>
    Fórmula:C27H28ClFN6O
    Forma y color:Solid
    Peso molecular:507
  • Mavelertinib

    CAS:
    <p>Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.</p>
    Fórmula:C18H22FN9O2
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:415.42
  • Osimertinib dimesylate

    CAS:
    <p>Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).</p>
    Fórmula:C30H41N7O8S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:691.82
  • Rociletinib hydrobromide

    CAS:
    <p>Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).</p>
    Fórmula:C27H29BrF3N7O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:636.46
  • Tyrphostin AG 879

    CAS:
    Fórmula:C18H24N2OS
    Pureza:>98.0%(HPLC)
    Forma y color:Light yellow to Yellow to Orange powder to crystal
    Peso molecular:316.46

    Ref: 3B-T3696

    5mg
    148,00€
    25mg
    546,00€
  • Brivanib

    CAS:
    <p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but &gt;240-fold against</p>
    Fórmula:C19H19FN4O3
    Pureza:98.87%
    Forma y color:Solid
    Peso molecular:370.38
  • Anti-EGFR Monoclonal Antibody


    <p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: FCM&lt;br&gt;<br>Reactivity: Human</p>
    Pureza:> 95% as determined by SDS-PAGE.
    Forma y color:Liquid
    Peso molecular:150 kDa
  • Anti-EGFR Monoclonal Antibody-Biotin


    <p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: FCM&lt;br&gt;<br>Reactivity: Human</p>
    Pureza:> 95% as determined by SDS-PAGE.
    Forma y color:Liquid
    Peso molecular:150 kDa
  • Tyrphostin B44, (+) enantiomer

    CAS:
    <p>Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)</p>
    Fórmula:C18H16N2O3
    Pureza:97.18%
    Forma y color:Solid
    Peso molecular:308.33
  • WHI-P154

    CAS:
    <p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>
    Fórmula:C16H14BrN3O3
    Pureza:98% - 99.67%
    Forma y color:Solid
    Peso molecular:376.2
  • ONO-7475

    CAS:
    <p>ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase</p>
    Fórmula:C32H26N4O6
    Pureza:98.74%
    Forma y color:Solid
    Peso molecular:562.57
  • Tucatinib

    CAS:
    <p>Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).</p>
    Fórmula:C26H24N8O2
    Pureza:99.05% - 99.96%
    Forma y color:Solid
    Peso molecular:480.52
  • Methyl 2,5-dihydroxycinnamate

    CAS:
    <p>Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.</p>
    Fórmula:C10H10O4
    Pureza:99.60%
    Forma y color:Crystalline
    Peso molecular:194.18
  • ZD-4190

    CAS:
    <p>ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.</p>
    Fórmula:C19H16BrFN6O2
    Pureza:99.12%
    Forma y color:Solid
    Peso molecular:459.27
  • Mutant EGFR inhibitor

    CAS:
    <p>Selective, potent inhibitor for mutated EGFR: L858R, Exon19 deletion, T790M resistance mutants.</p>
    Fórmula:C27H30ClN7O2
    Pureza:98% - 99.75%
    Forma y color:Solid
    Peso molecular:520.03
  • HG-14-10-04

    CAS:
    <p>HG-14-10-04 is a potent and specific ALK inhibitor.</p>
    Fórmula:C29H34ClN7O
    Pureza:99.75% - >99.99%
    Forma y color:Solid
    Peso molecular:532.08
  • TX1-85-1

    CAS:
    <p>TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.</p>
    Fórmula:C32H36N8O3
    Pureza:98.12% - 98.12%
    Forma y color:Solid
    Peso molecular:580.68
  • Alflutinib

    CAS:
    <p>Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition.</p>
    Fórmula:C28H31F3N8O2
    Pureza:99.87%
    Forma y color:Solid
    Peso molecular:568.59
  • Saracatinib

    CAS:
    <p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>
    Fórmula:C27H32ClN5O5
    Pureza:98% - 99.63%
    Forma y color:Solid
    Peso molecular:542.03
  • WS6

    CAS:
    <p>WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.</p>
    Fórmula:C29H31F3N6O3
    Pureza:97.65% - 99.95%
    Forma y color:Solid
    Peso molecular:568.59
  • Tuxobertinib

    CAS:
    <p>Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.</p>
    Fórmula:C29H29ClN6O4
    Pureza:99.22%
    Forma y color:Solid
    Peso molecular:561.03
  • Naquotinib

    CAS:
    <p>Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR</p>
    Fórmula:C30H42N8O3
    Pureza:97.49%
    Forma y color:Solid
    Peso molecular:562.71
  • Olafertinib

    CAS:
    <p>Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.</p>
    Fórmula:C29H28F2N6O2
    Pureza:98.62% - 99.706%
    Forma y color:Solid
    Peso molecular:530.57
  • KI8751

    CAS:
    <p>KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.</p>
    Fórmula:C24H18F3N3O4
    Pureza:99.22% - 99.9%
    Forma y color:Solid
    Peso molecular:469.41
  • FIIN-3

    CAS:
    <p>FIIN-3 is an irreversible inhibitor of FGFR.</p>
    Fórmula:C34H36Cl2N8O4
    Pureza:97.63% - 98.92%
    Forma y color:Solid
    Peso molecular:691.61
  • WZ8040

    CAS:
    <p>WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).</p>
    Fórmula:C24H25ClN6OS
    Pureza:97.42% - 99.785%
    Forma y color:Solid
    Peso molecular:481.01
  • ZM39923 hydrochloride

    CAS:
    <p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>
    Fórmula:C23H25NO·HCl
    Pureza:98.05%
    Forma y color:Solid
    Peso molecular:367.91
  • SU5214

    CAS:
    <p>SU5214 is a modulator of tyrosine kinase signal transduction.</p>
    Fórmula:C16H13NO2
    Pureza:99.45% - 99.55%
    Forma y color:Solid
    Peso molecular:251.28
  • Chrysophanol

    CAS:
    <p>Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.</p>
    Fórmula:C15H10O4
    Pureza:99.44% - 99.91%
    Forma y color:Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°C
    Peso molecular:254.24
  • AG490

    CAS:
    <p>AG490 inhibits EGFR (0.1 μM IC50), 135x &gt; selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>
    Fórmula:C17H14N2O3
    Pureza:98.6% - 99.39%
    Forma y color:Yellow Solid
    Peso molecular:294.3
  • SYR127063

    CAS:
    <p>SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.</p>
    Fórmula:C23H20ClF3N4O3
    Pureza:98.57%
    Forma y color:Solid
    Peso molecular:492.88
  • AZD8931 diFuMaric acid

    CAS:
    <p>AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).</p>
    Fórmula:C31H33ClFN5O11
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:706.1
  • CP-724714

    CAS:
    <p>CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), &gt;640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2</p>
    Fórmula:C27H27N5O3
    Pureza:97.1% - 98.82%
    Forma y color:Solid
    Peso molecular:469.54
  • PF-6274484

    CAS:
    <p>PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.</p>
    Fórmula:C18H14ClFN4O2
    Pureza:97.71%
    Forma y color:Solid
    Peso molecular:372.78
  • WS3

    CAS:
    WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.
    Fórmula:C28H30F3N7O3
    Pureza:97.93% - 99.94%
    Forma y color:Solid
    Peso molecular:569.58
  • CL-387785

    CAS:
    <p>CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.</p>
    Fórmula:C18H13BrN4O
    Pureza:99.56% - 99.62%
    Forma y color:Solid
    Peso molecular:381.23
  • PD168393

    CAS:
    <p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>
    Fórmula:C17H13BrN4O
    Pureza:99.13% - 99.83%
    Forma y color:Solid
    Peso molecular:369.22
  • lavendustin C

    CAS:
    <p>lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.</p>
    Fórmula:C14H13NO5
    Pureza:98.06%
    Forma y color:Yellow To Tan Powder
    Peso molecular:275.26
  • Canertinib

    CAS:
    <p>Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing growth and hypoxia.</p>
    Fórmula:C24H25ClFN5O3
    Pureza:98% - >99.99%
    Forma y color:White Or Similar To White Crystalline Powder
    Peso molecular:485.94
  • AG-1557 hydrochloride (189290-58-2(free base))


    AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
    Fórmula:C16H15ClIN3O2
    Pureza:98.64%
    Forma y color:Solid
    Peso molecular:443.66
  • Tyrphostin AG 879

    CAS:
    <p>Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.</p>
    Fórmula:C18H24N2OS
    Pureza:99.05%
    Forma y color:Solid
    Peso molecular:316.46
  • Daphnetin

    CAS:
    <p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>
    Fórmula:C9H6O4
    Pureza:97.47% - 99.8%
    Forma y color:Solid
    Peso molecular:178.14
  • NS309

    CAS:
    <p>NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.</p>
    Fórmula:C8H4Cl2N2O2
    Pureza:97.55%
    Forma y color:Solid
    Peso molecular:231.04
  • Cetuximab

    CAS:
    <p>Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM).</p>
    Fórmula:C107H179N35O36S7
    Pureza:95 - 98.60%
    Forma y color:Liquid
    Peso molecular:152 kDa
  • Endoxifen (Z-isomer)

    CAS:
    <p>Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.</p>
    Fórmula:C25H27NO2
    Pureza:99.19% - 99.81%
    Forma y color:Solid
    Peso molecular:373.49
  • Mubritinib

    CAS:
    <p>Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.</p>
    Fórmula:C25H23F3N4O2
    Pureza:98.61% - 99.85%
    Forma y color:Solid
    Peso molecular:468.47
  • Epitinib

    CAS:
    <p>Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).</p>
    Fórmula:C24H26N6O2
    Forma y color:Solid
    Peso molecular:430.5
  • AG1557

    CAS:
    <p>AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).</p>
    Fórmula:C16H14IN3O2
    Pureza:98.61% - 99.23%
    Forma y color:Solid
    Peso molecular:407.21
  • E-4031 dihydrochloride

    CAS:
    <p>E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)</p>
    Fórmula:C21H29Cl2N3O3S
    Pureza:99.31% - 99.87%
    Forma y color:Solid
    Peso molecular:474.44
  • Derazantinib dihydrochloride

    CAS:
    <p>Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.</p>
    Fórmula:C29H31Cl2FN4O
    Forma y color:Solid
    Peso molecular:541.49
  • Tyrphostin AG 528

    CAS:
    <p>Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).</p>
    Fórmula:C18H14N2O3
    Pureza:99.64%
    Forma y color:Solid
    Peso molecular:306.32
  • AG 1406

    CAS:
    <p>AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.</p>
    Fórmula:C16H18N2O
    Pureza:98.12%
    Forma y color:Solid
    Peso molecular:254.33
  • TAS0728

    CAS:
    <p>TAS0728 is a HER2 inhibitor, with antitumor activity</p>
    Fórmula:C26H32N8O3
    Pureza:97.78%
    Forma y color:Solid
    Peso molecular:504.58
  • NRC-2694

    CAS:
    <p>NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.</p>
    Fórmula:C24H26N4O3
    Pureza:99.90%
    Forma y color:Solid
    Peso molecular:418.49
  • Theliatinib

    CAS:
    <p>Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).</p>
    Fórmula:C25H26N6O2
    Pureza:99.67%
    Forma y color:Solid
    Peso molecular:442.51
  • (E)-AG 99

    CAS:
    <p>(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).</p>
    Fórmula:C10H8N2O3
    Pureza:99.23%
    Forma y color:Solid
    Peso molecular:204.18
  • JCN037

    CAS:
    <p>JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).</p>
    Fórmula:C16H11BrFN3O2
    Pureza:99.5%
    Forma y color:Solid
    Peso molecular:376.18
  • PKI-166 hydrochloride

    CAS:
    <p>EGFR-kinase inhibitor, IC50 0.7 nM, &gt;3000x selective, cuts metastasis and angiogenesis in mice, antihypertensive, oral use.</p>
    Fórmula:C20H19ClN4O
    Forma y color:Solid
    Peso molecular:366.85
  • SU 4313

    CAS:
    SU 4313 is a bioactive chemical.
    Fórmula:C18H17NO
    Pureza:99.51% - 99.89%
    Forma y color:Solid
    Peso molecular:263.33
  • EGFR/ErbB-2/ErbB-4 inhibitor-2

    CAS:
    <p>EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)</p>
    Fórmula:C23H21N3O3
    Pureza:99.55%
    Forma y color:Solid
    Peso molecular:387.43
  • Oritinib mesylate

    CAS:
    <p>Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.</p>
    Fórmula:C32H41N7O5S
    Forma y color:Solid
    Peso molecular:635.78
  • Theliatinib tartrate

    CAS:
    <p>Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), &gt;50x kinase selectivity.</p>
    Fórmula:C29H32N6O8
    Forma y color:Solid
    Peso molecular:592.6
  • Olmutinib

    CAS:
    <p>Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor</p>
    Fórmula:C26H26N6O2S
    Pureza:99.14%
    Forma y color:Solid
    Peso molecular:486.59
  • AEE788

    CAS:
    <p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>
    Fórmula:C27H32N6
    Pureza:98% - >99.99%
    Forma y color:Solid
    Peso molecular:440.58
  • WHI-P180

    CAS:
    <p>WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.</p>
    Fórmula:C16H15N3O3
    Pureza:99.21%
    Forma y color:Solid
    Peso molecular:297.31
  • NRC-2694 hydrochloride

    CAS:
    <p>NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.</p>
    Fórmula:C24H27ClN4O3
    Forma y color:Solid
    Peso molecular:454.95
  • Trastuzumab

    CAS:
    <p>Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.</p>
    Pureza:98% - SDS-PAGE: 97.1%;SEC-HPLC: 99.2%
    Forma y color:Liquid
    Peso molecular:Approximately 145.53 kDa
  • Sulforaphene

    CAS:
    <p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>
    Fórmula:C6H9NOS2
    Pureza:97.55% - 99.19%
    Forma y color:Slightly Yellowish Liquid
    Peso molecular:175.27
  • SU5204

    CAS:
    <p>SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and</p>
    Fórmula:C17H15NO2
    Pureza:99.46%
    Forma y color:Solid
    Peso molecular:265.31