EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 572 productos de "EGFR"
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Anti-EGFR Antibody (7X976)
<p>Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.</p>Forma y color:Odour LiquidAnti-Phospho-EGFR (Tyr1092) Antibody (9I899)
<p>Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.</p>Forma y color:Odour LiquidAnti-EGFR Antibody (3B845)
<p>Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.</p>Forma y color:Odour LiquidAnti-EGFR Antibody (9S619)
<p>Anti-EGFR Antibody (9S619) is an antibody targeting EGFR. Anti-EGFR Antibody (9S619) can be used in ELISA, IHC, FCM.</p>Forma y color:Odour LiquidEGFR Protein, Rhesus macaque, Recombinant (His)
<p>EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.</p>Forma y color:Lyophilized PowderPeso molecular:69.8 kDa (predicted). Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.Rilematovir
CAS:<p>Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.</p>Fórmula:C21H20ClF3N4O3SPureza:99.82%Forma y color:SolidPeso molecular:500.92Lapatinib Ditosylate
CAS:Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:925.46Neratinib maleate
CAS:<p>Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.</p>Fórmula:C34H33ClN6O7Pureza:99.64%Forma y color:SolidPeso molecular:673.11BMS-599626
CAS:Fórmula:C27H27FN8O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:530.56Canertinib
CAS:Fórmula:C24H25ClFN5O3Pureza:>98.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:485.94Tyrphostin RG 13022
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:266.30BI-4142
CAS:<p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>Fórmula:C28H27N9O2Pureza:97.21% - 98.09%Forma y color:SolidPeso molecular:521.57AEE 788
CAS:Fórmula:C27H32N6Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:440.60Vandetanib
CAS:Fórmula:C22H24BrFN4O2Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:475.36Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245)
<p>Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.</p>Forma y color:Odour LiquidWHI-P154
CAS:Fórmula:C16H14BrN3O3Pureza:>98.0%(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:376.21Tucatinib hemiethanolate
CAS:<p>Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.</p>Fórmula:C54H54N16O5Pureza:99.76%Forma y color:SolidPeso molecular:1007.11Hypericin
CAS:Fórmula:C30H16O8Pureza:>95.0%(HPLC)Forma y color:Black powder to crystalPeso molecular:504.45WHI-P180 Hydrochloride
CAS:Fórmula:C16H15N3O3·HClPureza:>97.0%(T)(HPLC)Forma y color:White to Light gray to Light yellow powder to crystalPeso molecular:333.77Neratinib
CAS:Fórmula:C30H29ClN6O3Pureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:557.05Tyrphostin RG 14620
CAS:Fórmula:C14H8Cl2N2Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:275.13PD 158780
CAS:Fórmula:C14H12BrN5Pureza:>97.0%(HPLC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:330.19Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:315.76EGFR vIII Protein, Human, Recombinant (hFc)
<p>EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.</p>Forma y color:Lyophilized PowderPeso molecular:90-120 KDa (reducing condition)EGFR Protein, Human, Recombinant (His & Avi)
<p>EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.Mubritinib
CAS:Fórmula:C25H23F3N4O2Pureza:>98.0%(HPLC)Forma y color:White to Gray to Brown powder to crystalPeso molecular:468.48Erlotinib-d6
CAS:<p>Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .</p>Fórmula:C22H23N3O4Pureza:98%Forma y color:SolidPeso molecular:399.47EGFR vIII Protein, Human, Recombinant (His)
<p>EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>Forma y color:Lyophilized PowderPeso molecular:61-75 Kda (reducing condition)EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:60-90 KDa (reducing condition)EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted)AV-412 free base
CAS:<p>AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).</p>Fórmula:C27H28ClFN6OForma y color:SolidPeso molecular:507Mavelertinib
CAS:<p>Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.</p>Fórmula:C18H22FN9O2Pureza:99.89%Forma y color:SolidPeso molecular:415.42Osimertinib dimesylate
CAS:<p>Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).</p>Fórmula:C30H41N7O8S2Pureza:98%Forma y color:SolidPeso molecular:691.82Rociletinib hydrobromide
CAS:<p>Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).</p>Fórmula:C27H29BrF3N7O3Pureza:98%Forma y color:SolidPeso molecular:636.46Tyrphostin AG 879
CAS:Fórmula:C18H24N2OSPureza:>98.0%(HPLC)Forma y color:Light yellow to Yellow to Orange powder to crystalPeso molecular:316.46Brivanib
CAS:<p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against</p>Fórmula:C19H19FN4O3Pureza:98.87%Forma y color:SolidPeso molecular:370.38Anti-EGFR Monoclonal Antibody
<p>Antibody Type: Rabbit Monoclonal<br><br>Application: FCM<br><br>Reactivity: Human</p>Pureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaAnti-EGFR Monoclonal Antibody-Biotin
<p>Antibody Type: Rabbit Monoclonal<br><br>Application: FCM<br><br>Reactivity: Human</p>Pureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaTyrphostin B44, (+) enantiomer
CAS:<p>Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)</p>Fórmula:C18H16N2O3Pureza:97.18%Forma y color:SolidPeso molecular:308.33WHI-P154
CAS:<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Fórmula:C16H14BrN3O3Pureza:98% - 99.67%Forma y color:SolidPeso molecular:376.2ONO-7475
CAS:<p>ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase</p>Fórmula:C32H26N4O6Pureza:98.74%Forma y color:SolidPeso molecular:562.57Tucatinib
CAS:<p>Tucatinib (ONT-380) is a potent and selective HER2 inhibitor (IC50: 8 nM).</p>Fórmula:C26H24N8O2Pureza:99.05% - 99.96%Forma y color:SolidPeso molecular:480.52Methyl 2,5-dihydroxycinnamate
CAS:<p>Methyl 2,5-dihydroxycinnamate is an EGF receptor-associated tyrosine kinases inhibitor.</p>Fórmula:C10H10O4Pureza:99.60%Forma y color:CrystallinePeso molecular:194.18ZD-4190
CAS:<p>ZD-4190 blocks VEGFR2 and EGFR, aiding cancer treatment.</p>Fórmula:C19H16BrFN6O2Pureza:99.12%Forma y color:SolidPeso molecular:459.27Mutant EGFR inhibitor
CAS:<p>Selective, potent inhibitor for mutated EGFR: L858R, Exon19 deletion, T790M resistance mutants.</p>Fórmula:C27H30ClN7O2Pureza:98% - 99.75%Forma y color:SolidPeso molecular:520.03HG-14-10-04
CAS:<p>HG-14-10-04 is a potent and specific ALK inhibitor.</p>Fórmula:C29H34ClN7OPureza:99.75% - >99.99%Forma y color:SolidPeso molecular:532.08TX1-85-1
CAS:<p>TX1-85-1: irreversible Her3 inhibitor (IC50: 23 nM), degrades Her3 protein, disrupts signaling, binds Cys721 covalently.</p>Fórmula:C32H36N8O3Pureza:98.12% - 98.12%Forma y color:SolidPeso molecular:580.68Alflutinib
CAS:<p>Alflutinib (ASK120067) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition.</p>Fórmula:C28H31F3N8O2Pureza:99.87%Forma y color:SolidPeso molecular:568.59Saracatinib
CAS:<p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>Fórmula:C27H32ClN5O5Pureza:98% - 99.63%Forma y color:SolidPeso molecular:542.03WS6
CAS:<p>WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.</p>Fórmula:C29H31F3N6O3Pureza:97.65% - 99.95%Forma y color:SolidPeso molecular:568.59Tuxobertinib
CAS:<p>Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.</p>Fórmula:C29H29ClN6O4Pureza:99.22%Forma y color:SolidPeso molecular:561.03Naquotinib
CAS:<p>Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR</p>Fórmula:C30H42N8O3Pureza:97.49%Forma y color:SolidPeso molecular:562.71Olafertinib
CAS:<p>Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.</p>Fórmula:C29H28F2N6O2Pureza:98.62% - 99.706%Forma y color:SolidPeso molecular:530.57KI8751
CAS:<p>KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.</p>Fórmula:C24H18F3N3O4Pureza:99.22% - 99.9%Forma y color:SolidPeso molecular:469.41FIIN-3
CAS:<p>FIIN-3 is an irreversible inhibitor of FGFR.</p>Fórmula:C34H36Cl2N8O4Pureza:97.63% - 98.92%Forma y color:SolidPeso molecular:691.61WZ8040
CAS:<p>WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).</p>Fórmula:C24H25ClN6OSPureza:97.42% - 99.785%Forma y color:SolidPeso molecular:481.01ZM39923 hydrochloride
CAS:<p>ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.</p>Fórmula:C23H25NO·HClPureza:98.05%Forma y color:SolidPeso molecular:367.91SU5214
CAS:<p>SU5214 is a modulator of tyrosine kinase signal transduction.</p>Fórmula:C16H13NO2Pureza:99.45% - 99.55%Forma y color:SolidPeso molecular:251.28Chrysophanol
CAS:<p>Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.</p>Fórmula:C15H10O4Pureza:99.44% - 99.91%Forma y color:Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°CPeso molecular:254.24AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Fórmula:C17H14N2O3Pureza:98.6% - 99.39%Forma y color:Yellow SolidPeso molecular:294.3SYR127063
CAS:<p>SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.</p>Fórmula:C23H20ClF3N4O3Pureza:98.57%Forma y color:SolidPeso molecular:492.88AZD8931 diFuMaric acid
CAS:<p>AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).</p>Fórmula:C31H33ClFN5O11Pureza:99.92%Forma y color:SolidPeso molecular:706.1CP-724714
CAS:<p>CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2</p>Fórmula:C27H27N5O3Pureza:97.1% - 98.82%Forma y color:SolidPeso molecular:469.54PF-6274484
CAS:<p>PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.</p>Fórmula:C18H14ClFN4O2Pureza:97.71%Forma y color:SolidPeso molecular:372.78WS3
CAS:<p>WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.</p>Fórmula:C28H30F3N7O3Pureza:97.93% - 99.94%Forma y color:SolidPeso molecular:569.58CL-387785
CAS:<p>CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.</p>Fórmula:C18H13BrN4OPureza:99.56% - 99.62%Forma y color:SolidPeso molecular:381.23PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Forma y color:SolidPeso molecular:369.22lavendustin C
CAS:<p>lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.</p>Fórmula:C14H13NO5Pureza:98.06%Forma y color:Yellow To Tan PowderPeso molecular:275.26Canertinib
CAS:<p>Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing growth and hypoxia.</p>Fórmula:C24H25ClFN5O3Pureza:98% - >99.99%Forma y color:White Or Similar To White Crystalline PowderPeso molecular:485.94AG-1557 hydrochloride (189290-58-2(free base))
<p>AG-1557 hydrochloride is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).</p>Fórmula:C16H15ClIN3O2Pureza:98.64%Forma y color:SolidPeso molecular:443.66Tyrphostin AG 879
CAS:<p>Tyrphostin AG 879 (AG 879) effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.</p>Fórmula:C18H24N2OSPureza:99.05%Forma y color:SolidPeso molecular:316.46Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14NS309
CAS:<p>NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.</p>Fórmula:C8H4Cl2N2O2Pureza:97.55%Forma y color:SolidPeso molecular:231.04Cetuximab
CAS:<p>Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM).</p>Fórmula:C107H179N35O36S7Pureza:95 - 98.60%Forma y color:LiquidPeso molecular:152 kDaEndoxifen (Z-isomer)
CAS:<p>Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.</p>Fórmula:C25H27NO2Pureza:99.19% - 99.81%Forma y color:SolidPeso molecular:373.49Mubritinib
CAS:<p>Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.</p>Fórmula:C25H23F3N4O2Pureza:98.61% - 99.85%Forma y color:SolidPeso molecular:468.47Epitinib
CAS:<p>Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).</p>Fórmula:C24H26N6O2Forma y color:SolidPeso molecular:430.5AG1557
CAS:<p>AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).</p>Fórmula:C16H14IN3O2Pureza:98.61% - 99.23%Forma y color:SolidPeso molecular:407.21E-4031 dihydrochloride
CAS:<p>E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)</p>Fórmula:C21H29Cl2N3O3SPureza:99.31% - 99.87%Forma y color:SolidPeso molecular:474.44Derazantinib dihydrochloride
CAS:<p>Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.</p>Fórmula:C29H31Cl2FN4OForma y color:SolidPeso molecular:541.49Tyrphostin AG 528
CAS:<p>Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).</p>Fórmula:C18H14N2O3Pureza:99.64%Forma y color:SolidPeso molecular:306.32AG 1406
CAS:<p>AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.</p>Fórmula:C16H18N2OPureza:98.12%Forma y color:SolidPeso molecular:254.33TAS0728
CAS:<p>TAS0728 is a HER2 inhibitor, with antitumor activity</p>Fórmula:C26H32N8O3Pureza:97.78%Forma y color:SolidPeso molecular:504.58NRC-2694
CAS:<p>NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.</p>Fórmula:C24H26N4O3Pureza:99.90%Forma y color:SolidPeso molecular:418.49Theliatinib
CAS:<p>Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).</p>Fórmula:C25H26N6O2Pureza:99.67%Forma y color:SolidPeso molecular:442.51(E)-AG 99
CAS:<p>(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).</p>Fórmula:C10H8N2O3Pureza:99.23%Forma y color:SolidPeso molecular:204.18JCN037
CAS:<p>JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).</p>Fórmula:C16H11BrFN3O2Pureza:99.5%Forma y color:SolidPeso molecular:376.18PKI-166 hydrochloride
CAS:<p>EGFR-kinase inhibitor, IC50 0.7 nM, >3000x selective, cuts metastasis and angiogenesis in mice, antihypertensive, oral use.</p>Fórmula:C20H19ClN4OForma y color:SolidPeso molecular:366.85SU 4313
CAS:<p>SU 4313 is a bioactive chemical.</p>Fórmula:C18H17NOPureza:99.51% - 99.89%Forma y color:SolidPeso molecular:263.33EGFR/ErbB-2/ErbB-4 inhibitor-2
CAS:<p>EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)</p>Fórmula:C23H21N3O3Pureza:99.55%Forma y color:SolidPeso molecular:387.43Oritinib mesylate
CAS:<p>Oritinib mesylate (SH-1028), an oral pyrimidine EGFR blocker with 18 nM IC50, targets both sensitive and T790M resistant mutations.</p>Fórmula:C32H41N7O5SForma y color:SolidPeso molecular:635.78Theliatinib tartrate
CAS:<p>Theliatinib: oral EGFR blocker, Ki 0.05 nM, IC50 3 nM (wild-type), 22 nM (T790M/L858R), >50x kinase selectivity.</p>Fórmula:C29H32N6O8Forma y color:SolidPeso molecular:592.6Olmutinib
CAS:<p>Olmutinib (BI1482694) is a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor</p>Fórmula:C26H26N6O2SPureza:99.14%Forma y color:SolidPeso molecular:486.59AEE788
CAS:<p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>Fórmula:C27H32N6Pureza:98% - >99.99%Forma y color:SolidPeso molecular:440.58WHI-P180
CAS:<p>WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.</p>Fórmula:C16H15N3O3Pureza:99.21%Forma y color:SolidPeso molecular:297.31NRC-2694 hydrochloride
CAS:<p>NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.</p>Fórmula:C24H27ClN4O3Forma y color:SolidPeso molecular:454.95Trastuzumab
CAS:<p>Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.</p>Pureza:98% - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Forma y color:LiquidPeso molecular:Approximately 145.53 kDaSulforaphene
CAS:<p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>Fórmula:C6H9NOS2Pureza:97.55% - 99.19%Forma y color:Slightly Yellowish LiquidPeso molecular:175.27SU5204
CAS:<p>SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and</p>Fórmula:C17H15NO2Pureza:99.46%Forma y color:SolidPeso molecular:265.31PP2
CAS:<p>PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.</p>Fórmula:C15H16ClN5Pureza:98% - 98.21%Forma y color:White SolidPeso molecular:301.77Tyrphostin AG30
CAS:<p>Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.</p>Fórmula:C10H7NO4Pureza:99.02%Forma y color:SolidPeso molecular:205.17PD-161570
CAS:<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Fórmula:C26H35Cl2N7OPureza:99.92%Forma y color:SolidPeso molecular:532.51Lazertinib
CAS:<p>Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.</p>Fórmula:C30H34N8O3Pureza:98.7% - 99.90%Forma y color:SolidPeso molecular:554.64Tyrphostin A1
CAS:<p>Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .</p>Fórmula:C11H8N2OPureza:98.32%Forma y color:SolidPeso molecular:184.19WZ4002
CAS:<p>WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.</p>Fórmula:C25H27ClN6O3Pureza:97.51%Forma y color:SolidPeso molecular:494.97MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Fórmula:C21H18N2OPureza:98.53%Forma y color:SolidPeso molecular:314.38Gefitinib-based PROTAC 3
CAS:<p>Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).</p>Fórmula:C47H57ClFN7O8SPureza:97.29% - 98.25%Forma y color:SolidPeso molecular:934.51Dacomitinib hydrate
CAS:<p>Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of</p>Fórmula:C24H27ClFN5O3Pureza:99.52%Forma y color:SolidPeso molecular:487.96Almonertinib
CAS:<p>Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.</p>Fórmula:C30H35N7O2Pureza:99.99%Forma y color:SolidPeso molecular:525.64G5-7
CAS:<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Fórmula:C22H19F2NO3Pureza:97.3%Forma y color:SolidPeso molecular:383.39AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Fórmula:C16H12N2O3Pureza:98.69%Forma y color:SolidPeso molecular:280.28Neratinib
CAS:<p>Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.</p>Fórmula:C30H29ClN6O3Pureza:96.17% - 99.85%Forma y color:SolidPeso molecular:557.04Osimertinib mesylate
CAS:<p>Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C29H37N7O5SPureza:99.46% - >99.99%Forma y color:SolidPeso molecular:595.71RG13022
CAS:<p>RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).</p>Fórmula:C16H14N2O2Pureza:98.38%Forma y color:SolidPeso molecular:266.29RG14620
CAS:<p>RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.</p>Fórmula:C14H8Cl2N2Pureza:99.82% - 99.87%Forma y color:SolidPeso molecular:275.13Allitinib tosylate
CAS:<p>Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.</p>Fórmula:C31H26ClFN4O5SPureza:98.46% - 98.68%Forma y color:SolidPeso molecular:621.08(S)-Sunvozertinib
CAS:<p>(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.</p>Fórmula:C29H35ClFN7O3Pureza:99.64%Forma y color:SolidPeso molecular:584.08BI-4020
CAS:<p>BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.</p>Fórmula:C30H38N8O2Pureza:97.21% - >99.99%Forma y color:SolidPeso molecular:542.68Avitinib
CAS:<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Forma y color:SolidPeso molecular:487.53Avitinib maleate
CAS:<p>Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.</p>Fórmula:C30H30FN7O6Pureza:98% - 99.74%Forma y color:SolidPeso molecular:603.61Alflutinib mesylate
CAS:<p>Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.</p>Fórmula:C29H35F3N8O5SPureza:97.94% - 99.63%Forma y color:SolidPeso molecular:664.7(E)-AG 556
CAS:<p>AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.</p>Fórmula:C20H20N2O3Pureza:99.93%Forma y color:Light Yellow PowderPeso molecular:336.38NSC 228155
CAS:<p>NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.</p>Fórmula:C11H6N4O4SPureza:99.84%Forma y color:SolidPeso molecular:290.25Afatinib Dimaleate
CAS:<p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Forma y color:SolidPeso molecular:718.08AZ-5104
CAS:<p>AZ5104 is a potent EGFR inhibitor.</p>Fórmula:C27H31N7O2Pureza:98.40% - 99.59%Forma y color:Solid PowderPeso molecular:485.58Dacomitinib
CAS:<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Forma y color:SolidPeso molecular:469.94Tyrphostin A9
CAS:<p>Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitor</p>Fórmula:C18H22N2OPureza:98.21% - 99.87%Forma y color:Yellow SolidPeso molecular:282.38Poziotinib hydrochloride
CAS:<p>Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.</p>Fórmula:C23H22Cl3FN4O3Pureza:99.69% - 99.81%Forma y color:SolidPeso molecular:527.8PP 3
CAS:<p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>Fórmula:C11H9N5Pureza:98.61%Forma y color:Whit To Off-White SolidPeso molecular:211.22Osimertinib
CAS:<p>Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.</p>Fórmula:C28H33N7O2Pureza:99.32% - >99.99%Forma y color:SolidPeso molecular:499.61Butein
CAS:<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Fórmula:C15H12O5Pureza:98.76% - >99.99%Forma y color:SolidPeso molecular:272.25PD158780
CAS:<p>PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.</p>Fórmula:C14H12BrN5Pureza:98.81%Forma y color:SolidPeso molecular:330.18β-Hydroxyisovalerylshikonin
CAS:<p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>Fórmula:C21H24O7Pureza:98.16%Forma y color:SolidPeso molecular:388.41TAS6417
CAS:<p>Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C23H20N6OPureza:99.71%Forma y color:SolidPeso molecular:396.44PD153035 hydrochloride
CAS:<p>PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.</p>Fórmula:C16H15BrClN3O2Pureza:99.39% - ≥95%Forma y color:SolidPeso molecular:396.67EAI045
CAS:<p>EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.</p>Fórmula:C19H14FN3O3SPureza:98.00% - 99.12%Forma y color:SolidPeso molecular:383.4AZ7550
CAS:<p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Fórmula:C27H31N7O2Pureza:97.07% - 99.75%Forma y color:SolidPeso molecular:485.58Epidermal Growth Factor
CAS:<p>EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.</p>Fórmula:C270H401N73O83S7Pureza:97.17%Forma y color:SolidPeso molecular:6222CP-380736
CAS:<p>CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.</p>Fórmula:C14H18N2O5Pureza:99.68%Forma y color:White To Off-White SolidPeso molecular:294.3Tyrphostin 23
CAS:<p>Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.</p>Fórmula:C10H6N2O2Pureza:99.7% - 99.86%Forma y color:Yellow-Tan SolidPeso molecular:186.17EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Forma y color:SolidPeso molecular:413.4ALK-IN-1
CAS:<p>ALK-IN-1 is a potent ALK inhibitor, demonstrating the ability to overcome Crizotinib resistance mediated by an L1196M mutation.</p>Fórmula:C26H34ClN6O2PPureza:99.74% - 99.80%Forma y color:SolidPeso molecular:529.01Zorifertinib
CAS:<p>Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.</p>Fórmula:C22H23ClFN5O3Pureza:98.20% - 99.36%Forma y color:White To Off-White SolidPeso molecular:459.9MTX-211
CAS:<p>MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.</p>Fórmula:C20H14Cl2FN5O2SPureza:97.6% - >99.99%Forma y color:SolidPeso molecular:478.33Desmethyl Erlotinib hydrochloride
CAS:<p>Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor.</p>Fórmula:C21H21N3O4·HClPureza:99.49%Forma y color:SolidPeso molecular:415.87AG 555
CAS:<p>AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.</p>Fórmula:C19H18N2O3Pureza:98.02% - 99.94%Forma y color:SolidPeso molecular:322.36WHI-P258
CAS:<p>WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.</p>Fórmula:C16H15N3O2Pureza:99.66% - 99.92%Forma y color:SolidPeso molecular:281.31AG-1478
CAS:<p>AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.</p>Fórmula:C16H14ClN3O2Pureza:99.03% - 99.71%Forma y color:SolidPeso molecular:315.75Desmethyl Erlotinib
CAS:<p>Desmethyl Erlotinib (CP-473420) is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).</p>Fórmula:C21H21N3O4Pureza:97.92% - 98.62%Forma y color:SolidPeso molecular:379.41Tesevatinib
CAS:<p>Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C24H25Cl2FN4O2Pureza:97.89% - 98.66%Forma y color:SolidPeso molecular:491.39EBE-A22
CAS:<p>EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.</p>Fórmula:C17H16BrN3O2Pureza:99.087% - 99.88%Forma y color:SolidPeso molecular:374.23Pelitinib
CAS:<p>Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).</p>Fórmula:C24H23ClFN5O2Pureza:98.37% - 99.84%Forma y color:Off-White SolidPeso molecular:467.92WZ-3146
CAS:<p>WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).</p>Fórmula:C24H25ClN6O2Pureza:97.15%Forma y color:SolidPeso molecular:464.95CZC-8004
CAS:<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Fórmula:C17H16FN5Pureza:99.29%Forma y color:SolidPeso molecular:309.34CNX-2006
CAS:<p>CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.</p>Fórmula:C26H27F4N7O2Pureza:98.85% - 99.16%Forma y color:SolidPeso molecular:545.53Sapitinib
CAS:<p>Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or</p>Fórmula:C23H25ClFN5O3Pureza:98.89% - 99.83%Forma y color:SolidPeso molecular:473.93Olmutinib
CAS:<p>Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.</p>Fórmula:C26H26N6O2SPureza:99.63%Forma y color:SolidPeso molecular:486.59Cyasterone
CAS:<p>Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising</p>Fórmula:C29H44O8Pureza:99.32% - 99.70%Forma y color:SolidPeso molecular:520.65Leptomycin B
CAS:<p>Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.</p>Fórmula:C33H48O6Pureza:97.10% - 99.04%Forma y color:White Crystalline SolidPeso molecular:540.73Genistein
CAS:<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>Fórmula:C15H10O5Pureza:98.22% - 99.64%Forma y color:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidPeso molecular:270.24Rostafuroxin
CAS:<p>Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.</p>Fórmula:C23H34O4Pureza:99.08% - >99.99%Forma y color:SolidPeso molecular:374.51Almonertinib mesylate
CAS:<p>Almonertinib mesylate: EGFR tyrosine kinase inhibitor, targets EGFR-mutant non-small cell lung cancer.</p>Fórmula:C31H39N7O5SPureza:99.92%Forma y color:SolidPeso molecular:621.75(Rac)-JBJ-04-125-02
CAS:<p>(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.</p>Fórmula:C29H26FN5O3SPureza:97.57%Forma y color:SolidPeso molecular:543.61Mobocertinib
CAS:<p>Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent</p>Fórmula:C32H39N7O4Pureza:99.47% - 99.97%Forma y color:SolidPeso molecular:585.7CUDC-101
CAS:<p>CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 and 15.7 nM, respectively.</p>Fórmula:C24H26N4O4Pureza:95.76% - 99.17%Forma y color:SolidPeso molecular:434.49Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Fórmula:C24H25ClFN5O3Pureza:98.56% - 99.9%Forma y color:Off-White SolidPeso molecular:485.94PD153035
CAS:<p>PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,</p>Fórmula:C16H14BrN3O2Pureza:98.47% - 99.29%Forma y color:SolidPeso molecular:360.21Nazartinib
CAS:<p>Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (</p>Fórmula:C26H31ClN6O2Pureza:98.63% - ≥95%Forma y color:Solid PowderPeso molecular:495.02PD-089828
CAS:<p>PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).</p>Fórmula:C18H18Cl2N6OPureza:97.39%Forma y color:SolidPeso molecular:405.28Gefitinib hydrochloride
CAS:<p>Obtustatin triacetate is an integrin derived from the venom of Vipera lebetina obtusa and is an α1β1 integrin and in vivo angiogenesis inhibitor.</p>Fórmula:C22H25Cl2FN4O3Pureza:99.8%Forma y color:SolidPeso molecular:483.36Cavutilide
CAS:<p>Cavutilide has antiarrhythmic activity, inhibits hERG K(+) channels, and can be used to study heart failure and persistent atrial fibrillation.</p>Fórmula:C22H26FN3O3Pureza:99.82% - 99.85%Forma y color:SolidPeso molecular:399.458Naquotinib mesylate
CAS:<p>Naquotinib mesylate (ASP8273 (mesylate)) is an orally available, mutant-selective and irreversible inhibitor of EGFR(iC50s of 8-33 nM and 230 nM for toward EGFR</p>Fórmula:C31H46N8O6SPureza:98%Forma y color:SolidPeso molecular:658.81Almonertinib hydrochloride
CAS:<p>Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation.</p>Fórmula:C30H36ClN7O2Pureza:98.01% - 98.12%Forma y color:SolidPeso molecular:562.1Canertinib dihydrochloride
CAS:<p>Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and</p>Fórmula:C24H27Cl3FN5O3Pureza:99.13% - >99.99%Forma y color:SolidPeso molecular:558.86BMS-690514
CAS:<p>BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.</p>Fórmula:C19H24N6O2Pureza:99.08%Forma y color:SolidPeso molecular:368.43Ponezumab
CAS:<p>Ponezumab (PF-04360365), a humanized IgG2 antibody, lowers Aβ in the CNS & boosts mice memory. Used in Alzheimer's research.</p>Forma y color:LiquidSerclutamab
CAS:<p>Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth factor receptor (EGFR).</p>Pureza:98%Forma y color:LiquidZalutumumab
CAS:<p>Zalutumumab is a high-affinity fully human monoclonal antibody ,the extracellular domain of the EGFR squamous cell carcinoma of the head and neck (SCCHN).</p>Pureza:95%Forma y color:LiquidElgemtumab
CAS:<p>Elgemtumab (LJM716) is a fully humanised monoclonal antibody targeting HER3/ERBB3, acting as an antagonist to block HER3/Akt phosphorylation antitumour.</p>Pureza:95%Forma y color:LiquidZanidatamab
CAS:<p>Zanidatamab (ZW25) is a bispecific, humanized monoclonal antibody that targets two distinct epitopes (ECD2 and ECD4) of the HER2 receptor, exhibiting anti-tumor</p>Forma y color:LiquidAnbenitamab
CAS:<p>Anbenitamab (KN-026) is a bispecific HER2 antibody for metastatic breast cancer research, blocking HER2 pathways and mediating ADCC.</p>Forma y color:LiquidBecotatug
CAS:<p>Becotatug (JMT-101) is an IgG1 antibody that targets EGFR and can be conjugated to Afatinib and Osimertinib, functioning as a synthetic antibody-drug conjugate</p>Pureza:95% - 95%Forma y color:LiquidDepatuxizumab
CAS:<p>Depatuxizumab is a humanised monoclonal antibody targeting EGFR with blood-brain barrier (BBB) permeability, inhibit tumor growth,GBM,SCCHN.</p>Pureza:95%Forma y color:LiquidFutuximab
CAS:<p>Futuximab, a chimeric monoclonal antibody, targets distinct epitopes on the epidermal growth factor receptor (EGFR), exhibiting antineoplastic activity [1].</p>Pureza:95% - 95%Forma y color:LiquidIzalontamab
CAS:<p>Izalontamab (SI-B001) is a bispecific EGFR/HER3 monoclonal antibody that binds to both EGFR×EGFR homodimers and EGFR×HER3 heterodimers.</p>Pureza:95%+ - 95%+Forma y color:LiquidImgatuzumab
CAS:<p>Imgatuzumab (RG 7160) is a humanized anti-EGFR monoclonal antibody and immunomodulator for cancer research.</p>Forma y color:LiquidPeso molecular:145.0 (kDa)lavendustin A
CAS:<p>lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.</p>Fórmula:C21H19NO6Pureza:98%Forma y color:Off-White SolidPeso molecular:381.38ZM323881 hydrochloride
CAS:<p>ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.</p>Fórmula:C22H19ClFN3O2Pureza:99.43%Forma y color:SolidPeso molecular:411.86Icotinib
CAS:<p>Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.</p>Fórmula:C22H21N3O4Pureza:99.76% - 99.94%Forma y color:SolidPeso molecular:391.42IGF-1R modulator 1
CAS:<p>IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), and 0.39 μM (TrkB). This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimer's disease.</p>Fórmula:C22H17N3O4Forma y color:SolidPeso molecular:387.39TAK-285
CAS:<p>TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.</p>Fórmula:C26H25ClF3N5O3Pureza:99.73%Forma y color:SolidPeso molecular:547.96Icotinib Hydrochloride
CAS:<p>Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.</p>Fórmula:C22H22ClN3O4Pureza:99.89%Forma y color:SolidPeso molecular:427.88Limertinib
CAS:<p>Limertinib (ASK120067) is a EGFR tyrosine kinase inhibitor targeting EGFR T790M, applicable for the study of non-small cell lung cancer.</p>Fórmula:C29H32ClN7O2Pureza:97.44%Forma y color:SolidPeso molecular:546.06EGFR/HER2-IN-9
CAS:<p>EGFR/HER2-IN-9, a compound inhibiting both EGFR and HER2, demonstrates potency with IC50 values of 3.2 nM for EGFR, 14 nM for HER2, and 8.3 nM against the EGFR</p>Fórmula:C25H25ClFN5O4Forma y color:SolidPeso molecular:513.95EGFR/C797S-IN-1
CAS:<p>EGFR/C797S-IN-1: Potent EGFR-C797S inhibitor, IC50 of 0.128 µM, dose-dependent p-EGFR suppression, anti-tumor properties.</p>Fórmula:C28H30N4O3Forma y color:SolidPeso molecular:470.56EAI001
CAS:<p>EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.</p>Fórmula:C19H15N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:349.41EGFR-IN-63
CAS:<p>EGFR- IN-63 is an EGFR inhibitor with an IC50 value of 0.096 μM. EGFR- IN-63 exhibited anticancer effects on MCF-7 cells (IC50: 2.49 μM).</p>Fórmula:C20H12BrN5SForma y color:SolidPeso molecular:434.31BIBX 1382 Dihydrochloride
CAS:<p>BIBX 1382 Dihydrochloride blocks Lassa/Ebola entry, aids in studying virus-host interactions, and hints at kinase targets for therapy.</p>Fórmula:C18H21Cl3FN7Forma y color:SolidPeso molecular:460.76(E/Z)-CP-724714
CAS:<p>(E/Z)-CP-724714, comprising racemic mixtures of (E)-CP-724714 and (Z)-CP-724714 isomers, is a potent, selective, and orally active inhibitor of ErbB2 (HER2)[1].</p>Fórmula:C27H27N5O3Pureza:98%Forma y color:SolidPeso molecular:469.54
