EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 572 productos de "EGFR"
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EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
<p>EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.</p>Forma y color:Lyophilized PowderPeso molecular:60-90 KDa (reducing condition)EGFR vIII Protein, Human, Recombinant (hFc)
<p>EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.</p>Forma y color:Lyophilized PowderPeso molecular:90-120 KDa (reducing condition)BMS-599626
CAS:Fórmula:C27H27FN8O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:530.56EGFR vIII Protein, Human, Recombinant (His)
<p>EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.</p>Forma y color:Lyophilized PowderPeso molecular:61-75 Kda (reducing condition)EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted)EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted). Due to glycosylation, the protein migrates to 60-78 kDa based on Tris-Bis PAGE result.Brivanib
CAS:<p>Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against</p>Fórmula:C19H19FN4O3Pureza:98.87%Forma y color:SolidPeso molecular:370.38CL-387785
CAS:Fórmula:C18H13BrN4OPureza:>98.0%(GC)Forma y color:White to Light yellow powder to crystalPeso molecular:381.23EGFRVIII Protein, Human, Recombinant (His & Avi)
<p>The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.</p>Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.Neratinib maleate
CAS:<p>Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.</p>Fórmula:C34H33ClN6O7Pureza:99.64%Forma y color:SolidPeso molecular:673.11Hypericin
CAS:Fórmula:C30H16O8Pureza:>95.0%(HPLC)Forma y color:Black powder to crystalPeso molecular:504.45Rociletinib hydrobromide
CAS:<p>Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).</p>Fórmula:C27H29BrF3N7O3Pureza:98%Forma y color:SolidPeso molecular:636.46Vandetanib
CAS:Fórmula:C22H24BrFN4O2Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:475.36Canertinib
CAS:Fórmula:C24H25ClFN5O3Pureza:>98.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:485.94Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:315.76PD 158780
CAS:Fórmula:C14H12BrN5Pureza:>97.0%(HPLC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:330.19Tyrphostin RG 14620
CAS:Fórmula:C14H8Cl2N2Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:275.13Neratinib
CAS:Fórmula:C30H29ClN6O3Pureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:557.05Mavelertinib
CAS:<p>Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.</p>Fórmula:C18H22FN9O2Pureza:99.89%Forma y color:SolidPeso molecular:415.42Tucatinib hemiethanolate
CAS:<p>Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.</p>Fórmula:C54H54N16O5Pureza:99.76%Forma y color:SolidPeso molecular:1007.11Osimertinib dimesylate
CAS:<p>Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).</p>Fórmula:C30H41N7O8S2Pureza:98%Forma y color:SolidPeso molecular:691.82AV-412 free base
CAS:<p>AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).</p>Fórmula:C27H28ClFN6OForma y color:SolidPeso molecular:507Mubritinib
CAS:Fórmula:C25H23F3N4O2Pureza:>98.0%(HPLC)Forma y color:White to Gray to Brown powder to crystalPeso molecular:468.48AEE 788
CAS:Fórmula:C27H32N6Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:440.60BI-4142
CAS:<p>BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.</p>Fórmula:C28H27N9O2Pureza:97.21% - 98.09%Forma y color:SolidPeso molecular:521.57Rilematovir
CAS:<p>Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.</p>Fórmula:C21H20ClF3N4O3SPureza:99.82%Forma y color:SolidPeso molecular:500.92Anti-EGFR Antibody (9S619)
<p>Anti-EGFR Antibody (9S619) is an antibody targeting EGFR. Anti-EGFR Antibody (9S619) can be used in ELISA, IHC, FCM.</p>Forma y color:Odour LiquidAnti-EGFR Antibody (3B845)
<p>Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.</p>Forma y color:Odour LiquidAnti-Phospho-EGFR (Tyr1092) Antibody (9I899)
<p>Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.</p>Forma y color:Odour LiquidAnti-EGFR Antibody (7X976)
<p>Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.</p>Forma y color:Odour LiquidAnti-Phospho-EGFR (Tyr1068) Antibody (3Q245)
<p>Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.</p>Forma y color:Odour LiquidWHI-P180 Hydrochloride
CAS:Fórmula:C16H15N3O3·HClPureza:>97.0%(T)(HPLC)Forma y color:White to Light gray to Light yellow powder to crystalPeso molecular:333.77Tyrphostin AG 879
CAS:Fórmula:C18H24N2OSPureza:>98.0%(HPLC)Forma y color:Light yellow to Yellow to Orange powder to crystalPeso molecular:316.46WHI-P154
CAS:Fórmula:C16H14BrN3O3Pureza:>98.0%(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:376.21Daphnetin
CAS:Fórmula:C9H6O4Pureza:>90.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:178.14Tyrphostin 8
CAS:<p>Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein</p>Fórmula:C10H6N2OPureza:99.86%Forma y color:SolidPeso molecular:170.17Tyrphostin RG 13022
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:266.30Anti-EGFR Monoclonal Antibody
<p>Antibody Type: Rabbit Monoclonal<br><br>Application: FCM<br><br>Reactivity: Human</p>Pureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaAnti-EGFR Monoclonal Antibody-Biotin
<p>Antibody Type: Rabbit Monoclonal<br><br>Application: FCM<br><br>Reactivity: Human</p>Pureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaNaquotinib
CAS:<p>Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR</p>Fórmula:C30H42N8O3Pureza:97.49%Forma y color:SolidPeso molecular:562.71SYR127063
CAS:<p>SYR127063 (BDBM-92454) (BDBM92454) is a potent and selective HER2 inhibitor, binds to HER2 in a reactive conformation.</p>Fórmula:C23H20ClF3N4O3Pureza:98.57%Forma y color:SolidPeso molecular:492.88Tuxobertinib
CAS:<p>Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.</p>Fórmula:C29H29ClN6O4Pureza:99.22%Forma y color:SolidPeso molecular:561.03AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Fórmula:C17H14N2O3Pureza:98.6% - 99.39%Forma y color:Yellow SolidPeso molecular:294.3Trastuzumab
CAS:<p>Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.</p>Pureza:98% - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Forma y color:LiquidPeso molecular:Approximately 145.53 kDaEpitinib
CAS:<p>Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).</p>Fórmula:C24H26N6O2Forma y color:SolidPeso molecular:430.5G5-7
CAS:<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Fórmula:C22H19F2NO3Pureza:97.3%Forma y color:SolidPeso molecular:383.39Chrysophanol
CAS:<p>Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.</p>Fórmula:C15H10O4Pureza:99.44% - 99.91%Forma y color:Physical Description Golden Yellow Plates Or Brown Powder Melting Point 196°CPeso molecular:254.24WZ4002
CAS:<p>WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.</p>Fórmula:C25H27ClN6O3Pureza:97.51%Forma y color:SolidPeso molecular:494.97MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Fórmula:C21H18N2OPureza:98.53%Forma y color:SolidPeso molecular:314.38PP 3
CAS:<p>PP 3 is a Negative control for the Src kinase inhibitor PP 2</p>Fórmula:C11H9N5Pureza:98.61%Forma y color:Whit To Off-White SolidPeso molecular:211.22
