EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 582 productos de "EGFR"
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EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted). Due to glycosylation, the protein migrates to 60-78 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00692
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.Forma y color:Lyophilized PowderPeso molecular:60-90 KDa (reducing condition)(3S,4S)-PF-06459988
CAS:(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Fórmula:C19H22ClN7O3Forma y color:SolidPeso molecular:431.88EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.Forma y color:Lyophilized PowderPeso molecular:41.6 kDa (predicted)Ref: TM-TMPK-00689
5µg150,00€10µg242,00€20µg405,00€50µg794,00€100µg1.343,00€200µg1.978,00€500µg3.455,00€EGFR Protein, Human, Recombinant (His & Avi)
EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.AG 1478 Hydrochloride
CAS:Fórmula:C16H14ClN3O2·HClPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:352.22Trichilinin D
CAS:Trichilinin D is a natural product that can be used in related research in the field of life sciences. Its product number is TN8637.Fórmula:C37H44O8Peso molecular:616.74Tyrphostin RG 14620
CAS:Fórmula:C14H8Cl2N2Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:275.13Canertinib
CAS:Fórmula:C24H25ClFN5O3Pureza:>98.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:485.94Mavelertinib
CAS:Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.Fórmula:C18H22FN9O2Pureza:99.89%Forma y color:SolidPeso molecular:415.42AV-412 free base
CAS:AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).Fórmula:C27H28ClFN6OForma y color:SolidPeso molecular:507PD 158780
CAS:Fórmula:C14H12BrN5Pureza:>97.0%(HPLC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:330.19Neratinib maleate
CAS:Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.Fórmula:C34H33ClN6O7Pureza:99.99%Forma y color:SolidPeso molecular:673.11CL-387785
CAS:Fórmula:C18H13BrN4OPureza:>98.0%(GC)Forma y color:White to Light yellow powder to crystalPeso molecular:381.23Osimertinib dimesylate
CAS:Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).Fórmula:C30H41N7O8S2Pureza:98%Forma y color:SolidPeso molecular:691.82Vandetanib
CAS:Fórmula:C22H24BrFN4O2Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:475.36Tyrphostin AG 490
CAS:Fórmula:C17H14N2O3Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:294.31Rociletinib hydrobromide
CAS:Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).Fórmula:C27H29BrF3N7O3Pureza:98%Forma y color:SolidPeso molecular:636.46Hypericin
CAS:Fórmula:C30H16O8Pureza:>95.0%(HPLC)Forma y color:Black powder to crystalPeso molecular:504.45WHI-P154
CAS:Fórmula:C16H14BrN3O3Pureza:>98.0%(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:376.21EGFR vIII Protein, Human, Recombinant (His)
EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Forma y color:Lyophilized PowderPeso molecular:61-75 Kda (reducing condition)Ref: TM-TMPJ-00648
1mg2.535,00€5µg90,00€10µg130,00€20µg193,00€50µg381,00€100µg600,00€200µg947,00€500µg1.765,00€Rilematovir
CAS:Rilematovir (JNJ-678) inhibits fusion protein, has antiviral properties, low toxicity, and targets RSV treatment.Fórmula:C21H20ClF3N4O3SPureza:99.95%Forma y color:SolidPeso molecular:500.92Tyrphostin AG 1478
CAS:Fórmula:C16H14ClN3O2Pureza:>98.0%(HPLC)Forma y color:Light orange to Yellow to Green powder to crystalPeso molecular:315.76Tyrphostin 8
CAS:Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits proteinFórmula:C10H6N2OPureza:97%Forma y color:SolidPeso molecular:170.17Tucatinib hemiethanolate
CAS:Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.Fórmula:C54H54N16O5Pureza:99.76%Forma y color:SolidPeso molecular:1007.11AEE 788
CAS:Fórmula:C27H32N6Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:440.60BI-4142
CAS:BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.Fórmula:C28H27N9O2Pureza:97.21% - 98.09%Forma y color:SolidPeso molecular:521.57Ref: TM-T63643
1mg57,00€5mg120,00€10mg177,00€25mg356,00€50mg537,00€100mg803,00€200mg1.341,00€1mL*10mM (DMSO)138,00€Mubritinib
CAS:Fórmula:C25H23F3N4O2Pureza:>98.0%(HPLC)Forma y color:White to Gray to Brown powder to crystalPeso molecular:468.48Tyrphostin AG 879
CAS:Fórmula:C18H24N2OSPureza:>98.0%(HPLC)Forma y color:Light yellow to Yellow to Orange powder to crystalPeso molecular:316.46Anti-EGFR Antibody (9S619)
Anti-EGFR Antibody (9S619) is an antibody targeting EGFR. Anti-EGFR Antibody (9S619) can be used in ELISA, IHC, FCM.Forma y color:Odour LiquidAnti-EGFR Antibody (3B845)
Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.Forma y color:Odour LiquidAnti-Phospho-EGFR (Tyr1092) Antibody (9I899)
Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.Forma y color:Odour LiquidAnti-EGFR Antibody (7X976)
Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.Forma y color:Odour LiquidAnti-Phospho-EGFR (Tyr1068) Antibody (3Q245)
Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.Forma y color:Odour LiquidWHI-P180 Hydrochloride
CAS:Fórmula:C16H15N3O3·HClPureza:>97.0%(T)(HPLC)Forma y color:White to Light gray to Light yellow powder to crystalPeso molecular:333.77BMS-599626
CAS:Fórmula:C27H27FN8O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:530.56Daphnetin
CAS:Fórmula:C9H6O4Pureza:>90.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:178.14Tyrphostin RG 13022
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:266.30Anti-EGFR Monoclonal Antibody-Biotin
Antibody Type: Rabbit Monoclonal
Application: FCM
Reactivity: HumanPureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaAnti-EGFR Monoclonal Antibody
Antibody Type: Rabbit Monoclonal
Application: FCM
Reactivity: HumanPureza:> 95% as determined by SDS-PAGE.Forma y color:LiquidPeso molecular:150 kDaTyrphostin AG 528
CAS:Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).Fórmula:C18H14N2O3Pureza:99.64%Forma y color:SolidPeso molecular:306.32Tyrphostin B44, (+) enantiomer
CAS:Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)Fórmula:C18H16N2O3Pureza:97.18%Forma y color:SolidPeso molecular:308.33Ref: TM-T22450
1mg39,00€5mg82,00€10mg115,00€25mg192,00€50mg264,00€100mg380,00€200mg515,00€1mL*10mM (DMSO)90,00€Derazantinib dihydrochloride
CAS:Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.Fórmula:C29H31Cl2FN4OForma y color:SolidPeso molecular:541.49Olafertinib
CAS:Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.Fórmula:C29H28F2N6O2Pureza:98.62% - 99.706%Forma y color:SolidPeso molecular:530.57PD153035 hydrochloride
CAS:PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
Fórmula:C16H15BrClN3O2Pureza:99.39% - ≥95%Forma y color:SolidPeso molecular:396.67G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Fórmula:C22H19F2NO3Pureza:97.3%Forma y color:SolidPeso molecular:383.39Ref: TM-T8742
1mg35,00€5mg71,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€1mL*10mM (DMSO)78,00€CL-387785
CAS:CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Fórmula:C18H13BrN4OPureza:99.56% - 99.62%Forma y color:SolidPeso molecular:381.23E-4031 dihydrochloride
CAS:E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Fórmula:C21H29Cl2N3O3SPureza:99.31% - 99.87%Forma y color:SolidPeso molecular:474.44AEE788
CAS:AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Fórmula:C27H32N6Pureza:98% - >99.99%Forma y color:SolidPeso molecular:440.58Ref: TM-T2116
2mg47,00€5mg70,00€10mg103,00€25mg188,00€50mg325,00€100mg490,00€500mg1.103,00€1mL*10mM (DMSO)77,00€AG-494
CAS:AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Fórmula:C16H12N2O3Pureza:98.69%Forma y color:SolidPeso molecular:280.28
