Syk
Los inhibidores de Syk (tirosina quinasa del bazo) son compuestos que se dirigen a Syk, una quinasa involucrada en la señalización de células inmunitarias y la regulación de la angiogénesis. Syk desempeña un papel en las respuestas inflamatorias que pueden contribuir a la angiogénesis tumoral. Inhibir Syk puede reducir la formación de vasos sanguíneos inducida por la inflamación en los tumores, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer y la investigación sobre inflamación. En CymitQuimica, ofrecemos una amplia gama de inhibidores de Syk de alta calidad para apoyar su investigación en inmunología, oncología y angiogénesis.
Se han encontrado 38 productos para "Syk".
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Piceatannol
CAS:Fórmula:C14H12O4Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:244.251,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS:Fórmula:C9H7NO4Pureza:98%Forma y color:SolidPeso molecular:193.15621,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS:Fórmula:C14H12O4Pureza:97%Forma y color:SolidPeso molecular:244.2427Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Fórmula:C9H11NO3·HClPureza:99.94%Forma y color:SolidPeso molecular:217.65Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Fórmula:C14H12O4Pureza:98.66% - 99.73%Forma y color:SolidPeso molecular:244.24Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Fórmula:C24H28N8O2Pureza:98.06% - 99.94%Forma y color:SolidPeso molecular:460.53Ref: TM-T14331
1mg39,00€5mg84,00€1mL*10mM (DMSO)85,00€10mg116,00€25mg178,00€50mg333,00€100mg495,00€200mg710,00€Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Fórmula:C23H25N9OPureza:98.35%Forma y color:SolidPeso molecular:443.5Ref: TM-T11824LL
1mg49,00€2mg71,00€5mg94,00€1mL*10mM (DMSO)109,00€10mg159,00€25mg275,00€50mg408,00€100mg600,00€Syk-IN-4
CAS:Syk-IN-4 is a potent, oral Syk inhibitor; blocks immune signaling; used for rheumatoid arthritis research.Fórmula:C21H25N9OForma y color:White SolidPeso molecular:419.48Ref: TM-T37077
1mg141,00€5mg335,00€1mL*10mM (DMSO)358,00€10mg597,00€25mg1.189,00€50mg1.935,00€100mg2.907,00€Tyrosine Kinase Inhibitor Library
A unique collection of xnum HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;Forma y color:Odour SolidRef: TM-L2200
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarSyk Kinase Peptide Substrate, Biotin labeled
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.Fórmula:C76H108N18O24S1Forma y color:SolidPeso molecular:1689.9Cevidoplenib dimesylate
CAS:Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.Fórmula:C27H35N7O9S2Pureza:98%Forma y color:Yellow SolidPeso molecular:665.74Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].Fórmula:C26H31N9O4Pureza:98%Forma y color:SolidPeso molecular:533.58MRL-SYKi
MRL-SYKi is a highly selective and potent chemical probe for spleen tyrosine kinase (SYK). In live cell assays, it strongly binds to SYK gain-of-function (GoF) variants [SYK(S550Y), SYK(S550F), and SYK(P342T)], with IC50 values of 2.1 nM, 14 nM, and 4.6 nM in digitonin-permeabilized cell experiments. MRL-SYKi effectively reduces catalytic activity, as shown in PhosphoSens SOX peptide assays, where the IC50 for SYK(S550F) is 63 nM and for SYK(P342T) is 95 nM. Additionally, it decreases phosphorylation levels at Y525/526 of SYK(S550Y) in SW480 cells. MRL-SYKi is useful for inflammation research.Lanraplenib succinate
CAS:Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Fórmula:C58H68N18O14Forma y color:SolidPeso molecular:1241.294MNS
CAS:Fórmula:C9H7NO4Pureza:>98.0%(GC)Forma y color:Light yellow to Yellow to Green powder to crystalPeso molecular:193.16BAY 61-3606 dihydrochloride
CAS:BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Fórmula:C20H18N6O3·2HClPureza:99.46%Forma y color:SolidPeso molecular:463.32Ref: TM-T6776
1mg35,00€5mg79,00€1mL*10mM (DMSO)93,00€10mg110,00€25mg177,00€50mg264,00€100mg385,00€200mg535,00€TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Fórmula:C17H22ClFN6OPureza:99.28% - 99.82%Forma y color:SolidPeso molecular:380.85BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibitingFórmula:C20H18N6O3Pureza:98.72%Forma y color:Yellow SolidPeso molecular:390.4R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Fórmula:C16H13FN4O2Pureza:99.27% - 99.84%Forma y color:Yellow SolidPeso molecular:312.3Ref: TM-T3185
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg207,00€50mg311,00€100mg462,00€500mg973,00€Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Fórmula:C23H24FN6O9P·2NaPureza:96.13% - 99.09%Forma y color:White SolidPeso molecular:624.42Ref: TM-T2605
1mg44,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)110,00€10mg117,00€25mg210,00€50mg354,00€100mg530,00€500mg1.153,00€
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