Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(6 productos)
- BCL(11 productos)
- Caspasa(127 productos)
- FOXO1(3 productos)
- IAP(66 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(126 productos)
- PDK(9 productos)
- PERK(23 productos)
- Serina / treonina quinasa(15 productos)
- Survivin(13 productos)
- TNF(91 productos)
- c-RET(51 productos)
- p53(62 productos)
Mostrar 6 subcategorías más
Se han encontrado 5618 productos de "Apoptosis"
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Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Fórmula:C6H9NO6Pureza:98.16%Forma y color:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecular:191.14MSC 2032964A
CAS:<p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>Fórmula:C16H13F3N6OPureza:99.76%Forma y color:SolidPeso molecular:362.31UAMC-3203 hydrochloride
CAS:<p>UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.</p>Fórmula:C25H38ClN5O2SPureza:99.62%Forma y color:SolidPeso molecular:508.12Paroxetine
CAS:<p>Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.</p>Fórmula:C19H20FNO3Pureza:98.89% - 99.45%Forma y color:White To Off-White PowderPeso molecular:329.37ML141
CAS:<p>ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).</p>Fórmula:C22H21N3O3SPureza:99.36% - 99.56%Forma y color:SolidPeso molecular:407.49CHS-828
CAS:<p>CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).</p>Fórmula:C19H22ClN5OPureza:98% - 99.9%Forma y color:SolidPeso molecular:371.86Ginsenoside F2
CAS:<p>Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.</p>Fórmula:C42H72O13Pureza:99.04% - 99.3%Forma y color:SolidPeso molecular:785.01LW6
CAS:<p>LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.</p>Fórmula:C26H29NO5Pureza:98.1% - 98.22%Forma y color:SolidPeso molecular:435.51Wogonin
CAS:<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Fórmula:C16H12O5Pureza:98% - 99.8%Forma y color:Yellow CrystalPeso molecular:284.26SW106065
CAS:<p>SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.</p>Fórmula:C10H8N2OSPureza:99.97%Forma y color:SolidPeso molecular:204.25(S)-(+)-Rolipram
CAS:<p>(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the</p>Fórmula:C16H21NO3Pureza:99.14%Forma y color:SolidPeso molecular:275.34Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Forma y color:SolidPeso molecular:532.61Nur77 modulator 1
CAS:<p>Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.</p>Fórmula:C28H25N5O2SPureza:99.62%Forma y color:SolidPeso molecular:495.6Candesartan Cilexetil
CAS:<p>Candesartan Cilexetil, an angiotensin II blocker (IC50: 0.26 nM), turns to candesartan in the body, which dilates blood vessels by hindering AT1.</p>Fórmula:C33H34N6O6Pureza:98.22% - >99.99%Forma y color:White Crystalline PowderPeso molecular:610.66CCPA
CAS:<p>CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptor</p>Fórmula:C15H20ClN5O4Pureza:99.1%Forma y color:Off-White To Light Yellow SolidPeso molecular:369.8KRIBB11
CAS:<p>KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.</p>Fórmula:C13H12N6O2Pureza:97.25% - 99.91%Forma y color:SolidPeso molecular:284.27Apomine
CAS:<p>Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。</p>Fórmula:C28H52O7P2Pureza:>99.99%Forma y color:SolidPeso molecular:562.66Iproniazid
CAS:<p>Iproniazid is an irreversible monoamine oxidase inhibitor. It is used as an antidepressive agent.</p>Fórmula:C9H13N3OPureza:98%Forma y color:SolidPeso molecular:179.22Asperosaponin VI
CAS:<p>Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.</p>Fórmula:C47H76O18Pureza:97.15% - 99.79%Forma y color:SolidPeso molecular:929.1TASIN-1
CAS:<p>TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).</p>Fórmula:C18H28N2O3SPureza:99.86%Forma y color:SolidPeso molecular:352.49Ginsenoside Rg6
CAS:<p>Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells</p>Fórmula:C42H70O12Pureza:97.34%Forma y color:SolidPeso molecular:767Formosanin C
CAS:<p>Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.</p>Fórmula:C51H82O20Pureza:99.75% - >99.99%Forma y color:SolidPeso molecular:1015.18Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Fórmula:C15H22N2OPureza:99.89%Forma y color:SolidPeso molecular:246.35Baicalein monohydrate
CAS:<p>Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.</p>Fórmula:C15H12O6Forma y color:SolidPeso molecular:288.25Cyasterone
CAS:<p>Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising</p>Fórmula:C29H44O8Pureza:99.32% - 99.70%Forma y color:SolidPeso molecular:520.65Thalidomide-5-methyl
CAS:Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.Fórmula:C14H12N2O4Pureza:99.48%Forma y color:SolidPeso molecular:272.26GSK2334470
CAS:<p>GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.</p>Fórmula:C25H34N8OPureza:99.57% - 99.87%Forma y color:SolidPeso molecular:462.59Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Fórmula:C11H11NO4SPureza:98.71%Forma y color:SolidPeso molecular:253.27EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Fórmula:C19H15F2NOPureza:99.71%Forma y color:SolidPeso molecular:311.33Masitinib
CAS:<p>Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.</p>Fórmula:C28H30N6OSPureza:97.56% - >99.99%Forma y color:SolidPeso molecular:498.64Dictamine
CAS:<p>Dictamine (Dectamine) shows anticholinesterase, anti-inflammatory, mutagenic, and has antimicrobial activity against bacteria and fungi.</p>Fórmula:C12H9NO2Pureza:99.72% - 99.889%Forma y color:SolidPeso molecular:199.21RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Fórmula:C23H21ClN2O5Pureza:98% - 99.96%Forma y color:SolidPeso molecular:440.88Schisandrin C
CAS:<p>Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.</p>Fórmula:C22H24O6Pureza:99.44% - 99.56%Forma y color:SolidPeso molecular:384.42Mancozeb
CAS:<p>Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.</p>Fórmula:C8H12MnN4S8ZnPureza:98%Forma y color:Grayish-Yellow PowderPeso molecular:541.08WM-3835
CAS:<p>WM-3835, a specific KAT7 inhibitor, potently halts OS cell growth, migration, and induces apoptosis.</p>Fórmula:C20H17FN2O4SPureza:97.78% - 99.36%Forma y color:SolidPeso molecular:400.42PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Forma y color:SolidPeso molecular:369.22Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Fórmula:C50H71N13O12Pureza:95% - >99.99%Forma y color:SolidPeso molecular:1046.18Venetoclax
CAS:<p>Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).</p>Fórmula:C45H50ClN7O7SPureza:98.00% - 99.97%Forma y color:SolidPeso molecular:868.44Quisinostat
CAS:Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.Fórmula:C21H26N6O2Pureza:96.01% - ≥98%Forma y color:SolidPeso molecular:394.47α-Hederin
CAS:<p>Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.</p>Fórmula:C41H66O12Pureza:99.44% - 99.89%Forma y color:SolidPeso molecular:750.96BMS-536924
CAS:<p>BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for</p>Fórmula:C25H26ClN5O3Pureza:99.02%Forma y color:SolidPeso molecular:479.963-Nitropropanoic acid
CAS:<p>3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.</p>Fórmula:C3H5NO4Pureza:98.35% - 99.94%Forma y color:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecular:119.08Genistein
CAS:<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>Fórmula:C15H10O5Pureza:98.22% - 99.64%Forma y color:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidPeso molecular:270.24(1E,6E)-Bis(demethoxy)curcumin
CAS:<p>(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.</p>Fórmula:C19H16O4Pureza:97.45%Forma y color:SolidPeso molecular:308.33Lupiwighteone
CAS:<p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>Fórmula:C20H18O5Pureza:98.92%Forma y color:SolidPeso molecular:338.35AZ 628
CAS:<p>AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc.</p>Fórmula:C27H25N5O2Pureza:99.50%Forma y color:SolidPeso molecular:451.52EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Forma y color:SolidPeso molecular:413.4SGI-1027
CAS:<p>SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).</p>Fórmula:C27H23N7OPureza:99.45% - 99.78%Forma y color:SolidPeso molecular:461.52Pembrolizumab
CAS:<p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>Pureza:95% - 99.70%Forma y color:LiquidPeso molecular:149 kDaGanoderic acid D
CAS:<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>Fórmula:C30H42O7Pureza:98.06% - 99.98%Forma y color:SolidPeso molecular:514.65Alvespimycin hydrochloride
CAS:Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.Fórmula:C32H48N4O8·HClPureza:99.94%Forma y color:SolidPeso molecular:653.21iCRT3
CAS:<p>iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.</p>Fórmula:C23H26N2O2SPureza:98.32% - 98.47%Forma y color:SolidPeso molecular:394.53Flavokawain A
CAS:<p>NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.</p>Fórmula:C18H18O5Pureza:97.1% - 99.72%Forma y color:SolidPeso molecular:314.332Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Forma y color:SolidPeso molecular:384.27SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Fórmula:C19H13Cl2N3O2SPureza:98.9%Forma y color:SolidPeso molecular:418.3Clobenpropit dihydrobromide
CAS:<p>Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)</p>Fórmula:C14H19Br2ClN4SPureza:99.86%Forma y color:SolidPeso molecular:470.7W-7 hydrochloride
CAS:<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Fórmula:C16H22Cl2N2O2SPureza:99.63%Forma y color:White Crystalline SolidPeso molecular:377.32RO8994
CAS:<p>RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).</p>Fórmula:C31H31Cl2FN4O4Pureza:99.31% - 99.44%Forma y color:SolidPeso molecular:613.51Rotenone
CAS:<p>Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.</p>Fórmula:C23H22O6Pureza:89.58% - 99.88%Forma y color:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Peso molecular:394.42TD52
CAS:TD52, an Erlotinib derivative, is an oral CIP2A cancer inhibitor that disrupts Elk1's attachment to the CIP2A promoter.Fórmula:C24H16N4Pureza:99.5%Forma y color:SolidPeso molecular:360.41Temsirolimus
CAS:<p>Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.</p>Fórmula:C56H87NO16Pureza:97.76% - >99.99%Forma y color:White Crystalline PowderPeso molecular:1030.29Amantadine
CAS:<p>Amantadine (1-Aminoadamantane), an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release and blocks dopamine reuptake.</p>Fórmula:C10H17NPureza:99.73% - 99.94%Forma y color:Hexakistetrahedral Crystals By Sublimation SolidPeso molecular:151.25Nitidine chloride
CAS:1.Fórmula:C21H18ClNO4Pureza:96.59% - 99.55%Forma y color:SolidPeso molecular:383.82MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Fórmula:C21H18N2OPureza:98.53%Forma y color:SolidPeso molecular:314.38MPI-0479605
CAS:<p>MPI-0479605 is an ATP competitive and selective inhibitor.</p>Fórmula:C22H29N7OPureza:97.59% - >99.99%Forma y color:SolidPeso molecular:407.51(S)-CPI203
CAS:<p>CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).</p>Fórmula:C19H18ClN5OSPureza:99.01% - 99.92%Forma y color:SolidPeso molecular:399.9Ginsenoside Rh2
CAS:<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Fórmula:C36H62O8Pureza:99.20% - 99.76%Forma y color:White PowderPeso molecular:622.87Epibrassinolide
CAS:<p>Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with</p>Fórmula:C28H48O6Pureza:97.57% - 98.11%Forma y color:SolidPeso molecular:480.68UTL-5g
CAS:<p>UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.</p>Fórmula:C11H8Cl2N2O2Pureza:99.83%Forma y color:SolidPeso molecular:271.1Oncrasin-1
CAS:<p>Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations</p>Fórmula:C16H12ClNOPureza:99.75%Forma y color:SolidPeso molecular:269.73Bioymifi
CAS:<p>Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.</p>Fórmula:C22H12BrN3O4SPureza:98% - 99.79%Forma y color:SolidPeso molecular:494.32Aniline mustard
CAS:<p>Aniline mustard (Mesylerythrol) is alkylating mustard with anti-neoplastic activity.</p>Fórmula:C10H13Cl2NPureza:99.54%Forma y color:SolidPeso molecular:218.12Glycitein
CAS:<p>1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.</p>Fórmula:C16H12O5Pureza:99.23% - 99.94%Forma y color:White PowderPeso molecular:284.26Glyphosate
CAS:<p>Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.</p>Fórmula:C3H8NO5PPureza:99.12% - 99.91%Forma y color:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)Peso molecular:169.07Radotinib
CAS:<p>Radotinib (IY-5511), and sometimes referred to by its investigational name IY5511, is a drug for the treatment of different types of Y, most notably</p>Fórmula:C27H21F3N8OPureza:99.13% - 99.97%Forma y color:SolidPeso molecular:530.5NSC 73150
CAS:<p>6-Methyl-1H-pyrimidin-4-one (NSC 73150) shows antitumor effects, impeding growth in breast, lung, liver cancer, and inducing apoptosis.</p>Fórmula:C12H12N4O2Pureza:99.84%Forma y color:SolidPeso molecular:244.25TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Fórmula:C10H14O2Pureza:99.17% - 99.53%Forma y color:White Solid PowderPeso molecular:166.22Kahweol
CAS:<p>Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB</p>Fórmula:C20H26O3Pureza:99.26% - 99.86%Forma y color:Off-White To Yellow SolidPeso molecular:314.42Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Forma y color:SolidPeso molecular:517.064E1rcat
CAS:<p>4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.</p>Fórmula:C28H18N2O6Pureza:99.47%Forma y color:SolidPeso molecular:478.45Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Fórmula:C28H26N4O3Pureza:99.24% - 99.82%Forma y color:Off-White PowderPeso molecular:466.53pimpinellin
CAS:<p>Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.</p>Fórmula:C13H10O5Pureza:99.85% - ≥95%Forma y color:SolidPeso molecular:246.22β-Lapachone
CAS:<p>β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.</p>Fórmula:C15H14O3Pureza:99.76% - 99.88%Forma y color:SolidPeso molecular:242.27MX69
CAS:<p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>Fórmula:C27H26N2O4SPureza:97.27% - 99.57%Forma y color:SolidPeso molecular:474.57DAPT
CAS:<p>DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.</p>Fórmula:C23H26F2N2O4Pureza:98.06% - 99.81%Forma y color:White SolidPeso molecular:432.46Bay 11-7085
CAS:<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Fórmula:C13H15NO2SPureza:99.76% - 99.94%Forma y color:White SolidPeso molecular:249.33BAM7
CAS:<p>BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).</p>Fórmula:C21H19N5O2SPureza:98.51% - 98.68%Forma y color:SolidPeso molecular:405.47Isocurcumenol
CAS:1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).Fórmula:C15H22O2Pureza:99.29% - ≥95%Forma y color:SolidPeso molecular:234.333BDO
CAS:<p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>Fórmula:C18H17NO5Pureza:97.76%Forma y color:SolidPeso molecular:327.33UNC1215
CAS:<p>UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).</p>Fórmula:C32H43N5O2Pureza:98% - 99.04%Forma y color:SolidPeso molecular:529.72Sodium dichloroacetate
CAS:<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Fórmula:C2HCl2NaO2Pureza:99.32% - 99.87%Forma y color:White PowderPeso molecular:150.92Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Fórmula:C39H43N3O11SPureza:≥98%Forma y color:SolidPeso molecular:761.84AES-350
CAS:<p>AES-350, an HDAC6 inhibitor (IC50: 0.0244 μM), also targets HDAC-3, -8, -11, induces AML cell apoptosis, and aids AML research.</p>Fórmula:C18H20N2O3Pureza:98.82%Forma y color:SolidPeso molecular:312.36NSC 15364
CAS:<p>NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.</p>Fórmula:C13H14N4OPureza:98.67%Forma y color:SolidPeso molecular:242.28Medicarpin
CAS:<p>Medicarpin, an ER agonist, stimulates osteoblasts, enhances peak bone mass, has no uterine effects, and is orally bioavailable.</p>Fórmula:C16H14O4Pureza:99.32% - 99.86%Forma y color:SolidPeso molecular:270.28Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Forma y color:Yellowish SolidPeso molecular:379.88Isobavachalcone
CAS:<p>Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in</p>Fórmula:C20H20O4Pureza:98% - 99.76%Forma y color:SolidPeso molecular:324.37Levomenol
CAS:<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Fórmula:C15H26OPureza:96.01%Forma y color:Clear To Yellowish LiquidPeso molecular:222.37CCT007093
CAS:<p>CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).</p>Fórmula:C15H12OS2Pureza:98% - 99.88%Forma y color:SolidPeso molecular:272.39Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFórmula:C20H19N3O·CH4O3SPureza:99.58% - 99.88%Forma y color:SolidPeso molecular:413.49
