Caspasa
Los inhibidores de caspasas son compuestos que bloquean la actividad de las caspasas, una familia de proteasas que son ejecutores centrales de la apoptosis. Las caspasas escinden sustratos específicos dentro de la célula para desencadenar el proceso apoptótico, lo que conduce a la muerte celular programada. Los inhibidores de caspasas se utilizan para estudiar los mecanismos de la apoptosis, así como para prevenir la muerte celular no deseada en varios modelos de investigación. Estos inhibidores también se exploran en contextos terapéuticos para proteger las células de la apoptosis en enfermedades como la neurodegeneración. En CymitQuimica, ofrecemos una amplia gama de inhibidores de caspasas de alta calidad para apoyar su investigación en apoptosis, muerte celular y campos relacionados.
Se han encontrado 178 productos para "Caspasa".
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Diclofenac sodium
CAS:Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions.Fórmula:C14H10Cl2NNaO2Pureza:98.21% - 99.92%Forma y color:SolidPeso molecular:318.13ML-9
CAS:ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Fórmula:C15H18Cl2N2O2SPureza:99.69%Forma y color:SolidPeso molecular:361.29Diclofenac diethylamine
CAS:Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).Fórmula:C18H22Cl2N2O2Pureza:99.81% - 99.87%Forma y color:SolidPeso molecular:369.29Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Fórmula:C9H8O4Pureza:99.78% - 99.91%Forma y color:SolidPeso molecular:180.1574Diclofenac
CAS:Diclofenac: a nonsteroidal compound inhibiting COX-1 and COX-2, reducing pro-inflammatory prostaglandins.Fórmula:C14H11Cl2NO2Pureza:99.69% - 99.99%Forma y color:White SolidPeso molecular:296.149Inclisiran sodium
CAS:Inclisiran (ALN-PCSsc) possesses antihypertensive activity, inhibiting the transcription of PCSK9, and can be used to research cardiovascular diseases.Pureza:99.29%Forma y color:Odour SolidAc-FLTD-CMK
CAS:Ac-FLTD-CMK, an abscisicin D derivative, selectively inhibits inflammatory caspases-1, -4, and -11 (IC50: 46.7 nM, 1.49 μM, 329 nM) but not caspase-3.Fórmula:C26H37ClN4O8Pureza:98.61%Forma y color:SolidPeso molecular:569.047Ac-YVAD-CMK
CAS:Ac-YVAD-CMK: Irreversible Caspase-1 inhibitor; halts pyroptosis, IL-1β/IL-18; neuroprotective and anti-inflammatory.Fórmula:C24H33ClN4O8Pureza:97.08% - 99.90%Forma y color:White SolidPeso molecular:540.994Q-VD-OPH
CAS:Q-VD-OPh is an irreversible caspase inhibitor with an IC50 value of 48 nM against caspase-7 and between 25 and 400 nM against caspase-1, 3, 8, 9, 10, 12.Fórmula:C26H25F2N3O6Pureza:97.8% - 99.96%Forma y color:SolidPeso molecular:513.49Crustecdysone
CAS:Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.Fórmula:C27H44O7Pureza:99.06% - 99.67%Forma y color:White SolidPeso molecular:480.6341Thiabendazole
CAS:Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.Fórmula:C10H7N3SPureza:99.14%Forma y color:White SolidPeso molecular:201.248Fenbufen
CAS:Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis.Fórmula:C16H14O3Pureza:98.35% - 98.74%Forma y color:White SolidPeso molecular:254.2806Lacidipine
CAS:Lacidipine (SN-305) is a slow-acting, long-duration lipophilic dihydropyridine calcium blocker that prevents reflex tachycardia and lowers blood pressure.Fórmula:C26H33NO6Pureza:99.98%Forma y color:White-To-Off-White Crystalline SolidPeso molecular:455.54Dehydrocorydaline chloride
CAS:Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.Fórmula:C22H24ClNO4Pureza:99.53%Forma y color:SolidPeso molecular:401.883Terfenadine
CAS:Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.Fórmula:C32H41NO2Pureza:98.76% - 99.97%Forma y color:SolidPeso molecular:471.67Oxidopamine hydrochloride
CAS:Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.Fórmula:C8H12ClNO3Pureza:98.34% - 99.85%Forma y color:White SolidPeso molecular:205.639Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Fórmula:C8H12BrNO3Pureza:98.59% - 99.88%Forma y color:Brown SolidPeso molecular:250.09Ac-VDVAD-CHO TFA
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor with IC50 values of 46 nM and 15 nM, respectively.Forma y color:Odour SolidNEK7 degrader-1
CAS:NEK7 degrader-1 is a molecular glue degrader (DC₅₀ = 0.1 nM) that inhibits caspase-1 and IL-1β release.Fórmula:C21H22Cl2N4O3Pureza:97.02%Peso molecular:449.33HDAC3 degrader-1
HDAC3degrader-1 (Compound Z8) is a selective HDAC3 degrader with a DC50 of 2.42 μM. It shows minimal impact on HDAC1, HDAC2, and HDAC6. By inhibiting the activation of the NLRP3 inflammasome, HDAC3degrader-1 reduces the secretion of IL-1β and caspase-1. It demonstrates significant efficacy in models of septic shock and colitis, making it valuable for anti-inflammatory research.
