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Apoptosis

Apoptosis

Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.

Subcategorías de "Apoptosis"

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Se han encontrado 5622 productos de "Apoptosis"

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  • Avelumab

    CAS:
    <p>Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.</p>
    Pureza:95% - 97.17% (SDS-PAGE)
    Forma y color:Liquid
    Peso molecular:143.8 kDa
  • Chelerythrine

    CAS:
    <p>1.</p>
    Fórmula:C21H18NO4
    Pureza:98.36%
    Forma y color:Solid
    Peso molecular:348.37
  • Fedratinib

    CAS:
    Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.
    Fórmula:C27H36N6O3S
    Pureza:97.31% - 99.96%
    Forma y color:Solid
    Peso molecular:524.68
  • Sesamol

    CAS:
    <p>Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats.</p>
    Fórmula:C7H6O3
    Pureza:99.67% - 99.76%
    Forma y color:White To Off-White Crystalline Powder
    Peso molecular:138.12
  • 2BAct

    CAS:
    <p>2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response</p>
    Fórmula:C19H16ClF3N4O3
    Pureza:97.97% - 99.04%
    Forma y color:Solid
    Peso molecular:440.8
  • Mitoxantrone diacetate

    CAS:
    <p>Mitoxantrone diacetate hinders topoisomerase II &amp; PKC, fights tumors &amp; orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>
    Fórmula:C26H36N4O10
    Forma y color:Solid
    Peso molecular:564.592
  • NS-1619

    CAS:
    NS1619 have cardio-protective effects after ischemia-reperfusion injury.
    Fórmula:C15H8F6N2O2
    Pureza:97.66% - 98%
    Forma y color:Solid
    Peso molecular:362.23
  • B355252

    CAS:
    <p>B355252 prevents glutamate-induced cell death and boosts NGF's nerve growth effects.</p>
    Fórmula:C25H24ClN3O3S2
    Pureza:98.73% - 99.92%
    Forma y color:Solid
    Peso molecular:514.06
  • Fasentin

    CAS:
    <p>Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.</p>
    Fórmula:C11H9ClF3NO2
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:279.64
  • SKLB-163

    CAS:
    <p>SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.</p>
    Fórmula:C18H16ClN3O2S2
    Pureza:99.23%
    Forma y color:Solid
    Peso molecular:405.92
  • PFI-1

    CAS:
    <p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>
    Fórmula:C16H17N3O4S
    Pureza:98.74% - 99.19%
    Forma y color:Solid
    Peso molecular:347.39
  • PD146176

    CAS:
    <p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>
    Fórmula:C15H11NS
    Pureza:98.00%
    Forma y color:Solid
    Peso molecular:237.32
  • UMI-77

    CAS:
    <p>UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1.Cost-effective and quality-assured.</p>
    Fórmula:C18H14BrNO5S2
    Pureza:96% - 99.57%
    Forma y color:Solid
    Peso molecular:468.34
  • ACBI1

    CAS:
    ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s
    Fórmula:C49H58FN9O7S
    Pureza:97.54% - 98.15%
    Forma y color:Solid
    Peso molecular:936.1
  • Lycorine

    CAS:
    <p>Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.</p>
    Fórmula:C16H17NO4
    Pureza:98.60% - 99.95%
    Forma y color:Solid
    Peso molecular:287.31
  • Linifanib

    CAS:
    <p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>
    Fórmula:C21H18FN5O
    Pureza:98% - 98.24%
    Forma y color:Solid
    Peso molecular:375.4
  • Ginsenoside F5

    CAS:
    <p>Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway</p>
    Fórmula:C41H70O13
    Pureza:99.78% - 99.86%
    Forma y color:Solid
    Peso molecular:770.99
  • [8]-Shogaol

    CAS:
    [8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.
    Fórmula:C19H28O3
    Pureza:97.01%
    Forma y color:Solid
    Peso molecular:304.42
  • BAY 61-3606 dihydrochloride

    CAS:
    <p>BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).</p>
    Fórmula:C20H18N6O3·2HCl
    Pureza:99.46%
    Forma y color:Solid
    Peso molecular:463.32
  • SSE15206

    CAS:
    SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance.
    Fórmula:C19H21N3O3S
    Pureza:98.81%
    Forma y color:Solid
    Peso molecular:371.45
  • MGH-CP1

    CAS:
    <p>MGH-CP1 inhibits TEAD2/4 auto-palmitoylation with IC50 of 710 and 672 nM, respectively.</p>
    Fórmula:C20H24N4OS
    Pureza:98.66%
    Forma y color:Solid
    Peso molecular:368.5
  • Ac-DEVD-CHO acetate


    <p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>
    Fórmula:C22H34N4O13
    Pureza:98.54%
    Forma y color:Solid
    Peso molecular:562.52
  • Thalidomide-PEG4-Propargyl

    CAS:
    <p>Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.</p>
    Fórmula:C24H28N2O9
    Pureza:97.46%
    Forma y color:Solid
    Peso molecular:488.49
  • MG-101

    CAS:
    <p>MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.</p>
    Fórmula:C20H37N3O4
    Pureza:98% - ≥98%
    Forma y color:Solid
    Peso molecular:383.53
  • Estramustine phosphate sodium

    CAS:
    Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.
    Fórmula:C23H30Cl2NNa2O6P
    Pureza:96.44% - 99.54%
    Forma y color:Solid
    Peso molecular:564.35
  • Rigosertib sodium

    CAS:
    <p>Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.</p>
    Fórmula:C21H24NNaO8S
    Pureza:98% - 99.37%
    Forma y color:Solid
    Peso molecular:473.47
  • R-7050

    CAS:
    <p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>
    Fórmula:C16H8ClF3N4S
    Pureza:98.64% - 99.8%
    Forma y color:Solid
    Peso molecular:380.77
  • Tenovin-1

    CAS:
    <p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>
    Fórmula:C20H23N3O2S
    Pureza:99.33%
    Forma y color:Solid
    Peso molecular:369.48
  • Pogostone

    CAS:
    <p>Pogostone: anti-bacterial/fungal, blocks T-cells, modulates cytokines, protects against gastric ulcers, boosts antioxidants/PGE2/NP-SH.</p>
    Fórmula:C12H16O4
    Pureza:98.46% - 99.03%
    Forma y color:Solid
    Peso molecular:224.25
  • SecinH3

    CAS:
    <p>SecinH3 is selective cytohesin inhibitor.</p>
    Fórmula:C24H20N4O4S
    Pureza:97.49% - 99.37%
    Forma y color:Solid
    Peso molecular:460.51
  • AC1NS4RE

    CAS:
    <p>It is a tyrosine kinase inhibitor.</p>
    Fórmula:C15H13ClN2O
    Pureza:99.53%
    Forma y color:Solid
    Peso molecular:272.73
  • Acacetin

    CAS:
    <p>Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidant</p>
    Fórmula:C16H12O5
    Pureza:96.26% - ≥95%
    Forma y color:Pale-Yellow Needles
    Peso molecular:284.26
  • VK3-OCH3

    CAS:
    VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.
    Fórmula:C14H14O3S
    Pureza:99.71%
    Forma y color:Solid
    Peso molecular:262.32
  • CAY10505

    CAS:
    <p>CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).</p>
    Fórmula:C14H8FNO3S
    Pureza:99.69% - 99.74%
    Forma y color:Solid
    Peso molecular:289.28
  • Taurochenodeoxycholic Acid

    CAS:
    <p>Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.</p>
    Fórmula:C26H45NO6S
    Pureza:99.53% - 99.86%
    Forma y color:Solid
    Peso molecular:499.7
  • MRS 2578

    CAS:
    MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.
    Fórmula:C20H20N6S4
    Pureza:97.58% - 99.73%
    Forma y color:White Solid
    Peso molecular:472.67
  • (+)-Nortrachelogenin

    CAS:
    <p>(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.</p>
    Fórmula:C20H22O7
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:374.38
  • Valepotriate

    CAS:
    <p>Valepotriates are sedative, enhance memory, have anti-cancer properties, and may reduce anxiety.</p>
    Fórmula:C22H30O8
    Pureza:97.29% - 99.90%
    Forma y color:Solid
    Peso molecular:422.47
  • Polyphyllin I

    CAS:
    <p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>
    Fórmula:C44H70O16
    Pureza:98% - 99.5%
    Forma y color:Solid
    Peso molecular:855.02
  • Antineoplaston A10

    CAS:
    Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.
    Fórmula:C13H14N2O3
    Pureza:99.42%
    Forma y color:Solid
    Peso molecular:246.26
  • Epothilone A

    CAS:
    <p>Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.</p>
    Fórmula:C26H39NO6S
    Pureza:99.89% - 99.92%
    Forma y color:Solid
    Peso molecular:493.66
  • L-685458

    CAS:
    <p>L-685458 (L-685,458) is a specific and potent inhibitor of A beta PP gamma-secretase activity with Ki of 17 nM.</p>
    Fórmula:C39H52N4O6
    Pureza:99.62% - 99.80%
    Forma y color:Solid
    Peso molecular:672.85
  • 18α-Glycyrrhetinic acid

    CAS:
    <p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>
    Fórmula:C30H46O4
    Pureza:98.54% - 99.68%
    Forma y color:Solid
    Peso molecular:470.68
  • G5-7

    CAS:
    <p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>
    Fórmula:C22H19F2NO3
    Pureza:97.3%
    Forma y color:Solid
    Peso molecular:383.39
  • YK-4-279

    CAS:
    <p>YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.</p>
    Fórmula:C17H13Cl2NO4
    Pureza:99.80% - ≥95%
    Forma y color:Solid
    Peso molecular:366.2
  • OTS514 hydrochloride

    CAS:
    OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).
    Fórmula:C21H20N2O2S·HCl
    Pureza:99.67% - 99.84%
    Forma y color:Solid
    Peso molecular:400.92
  • Kynurenic acid sodium

    CAS:
    Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.
    Fórmula:C10H6NNaO3
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:211.15
  • MK-886

    CAS:
    MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).
    Fórmula:C27H34ClNO2S
    Pureza:99.23% - 99.84%
    Forma y color:Solid
    Peso molecular:472.08
  • Terrestrosin D

    CAS:
    <p>Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.</p>
    Fórmula:C50H80O23
    Pureza:99.92% - 99.96%
    Forma y color:Solid
    Peso molecular:1049.16
  • Xanthatin

    CAS:
    Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.
    Fórmula:C15H18O3
    Pureza:98.48% - 99.96%
    Forma y color:Solid
    Peso molecular:246.3
  • CASIN

    CAS:
    CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).
    Fórmula:C20H22N2O
    Pureza:98.18% - >99.99%
    Forma y color:Solid
    Peso molecular:306.4
  • NU 7026

    CAS:
    NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition
    Fórmula:C17H15NO3
    Pureza:99.51% - >99.99%
    Forma y color:Solid
    Peso molecular:281.31
  • Lithocholic acid

    CAS:
    Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!
    Fórmula:C24H40O3
    Pureza:98% - 99.93%
    Forma y color:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)
    Peso molecular:376.57
  • SKF-96365 hydrochloride

    CAS:
    <p>SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y</p>
    Fórmula:C22H27ClN2O3
    Pureza:99.47% - 99.92%
    Forma y color:Solid
    Peso molecular:402.91
  • Xanthohumol

    CAS:
    <p>Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-</p>
    Fórmula:C21H22O5
    Pureza:98.19% - 99.67%
    Forma y color:Orange Powder
    Peso molecular:354.4
  • Palmatine

    CAS:
    <p>Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.</p>
    Fórmula:C21H22NO4
    Pureza:96.28% - 99.49%
    Forma y color:Solid
    Peso molecular:352.4
  • Midostaurin

    CAS:
    <p>PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.</p>
    Fórmula:C35H30N4O4
    Pureza:97.61% - >99.99%
    Forma y color:Solid
    Peso molecular:570.64
  • Suramin Sodium Salt

    CAS:
    <p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>
    Fórmula:C51H34N6Na6O23S6
    Pureza:97.47% - 99.97%
    Forma y color:White
    Peso molecular:1429.15
  • Thalidomide-O-amido-C3-NH2 TFA

    CAS:
    <p>Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.</p>
    Fórmula:C20H21F3N4O8
    Pureza:98.47%
    Forma y color:Solid
    Peso molecular:502.4
  • AZD0156

    CAS:
    <p>AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.</p>
    Fórmula:C26H31N5O3
    Pureza:99.13% - 99.87%
    Forma y color:Solid
    Peso molecular:461.56
  • TG101209

    CAS:
    <p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>
    Fórmula:C26H35N7O2S
    Pureza:99% - >99.99%
    Forma y color:Solid
    Peso molecular:509.67
  • MGCD-265 analog

    CAS:
    <p>Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.</p>
    Fórmula:C26H20FN5O2S2
    Pureza:98.06% - 98.68%
    Forma y color:Solid
    Peso molecular:517.6
  • Valinomycin

    CAS:
    <p>Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin</p>
    Fórmula:C54H90N6O18
    Pureza:95.37% - 97.16%
    Forma y color:White Solid
    Peso molecular:1111.32
  • LYN-1604

    CAS:
    <p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>
    Fórmula:C33H43Cl2N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:584.62
  • AEE788

    CAS:
    <p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>
    Fórmula:C27H32N6
    Pureza:98% - >99.99%
    Forma y color:Solid
    Peso molecular:440.58
  • BMS-202

    CAS:
    <p>BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.</p>
    Fórmula:C25H29N3O3
    Pureza:97.92% - 99.66%
    Forma y color:Solid
    Peso molecular:419.52
  • Ganetespib

    CAS:
    <p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>
    Fórmula:C20H20N4O3
    Pureza:98% - 99.95%
    Forma y color:Solid
    Peso molecular:364.4
  • AZ960

    CAS:
    <p>AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: &lt;3 nM and0.45 nM).</p>
    Fórmula:C18H16F2N6
    Pureza:96.02% - 98.51%
    Forma y color:Solid
    Peso molecular:354.36
  • Gemcitabine hydrochloride

    CAS:
    Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.
    Fórmula:C9H11F2N3O4·HCl
    Pureza:99.28% - 99.98%
    Forma y color:White Crystalline Granular Odorless
    Peso molecular:299.66
  • ASK1-IN-1

    CAS:
    ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.
    Fórmula:C19H19N9O2
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:405.41
  • WP1066

    CAS:
    <p>WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.</p>
    Fórmula:C17H14BrN3O
    Pureza:98.92% - 99.73%
    Forma y color:Solid
    Peso molecular:356.22
  • JNJ-7706621

    CAS:
    <p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>
    Fórmula:C15H12F2N6O3S
    Pureza:99.1% - 99.85%
    Forma y color:Solid
    Peso molecular:394.36
  • PU02

    CAS:
    <p>PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.</p>
    Fórmula:C16H12N4S
    Pureza:99.35%
    Forma y color:Solid
    Peso molecular:292.36
  • SBI-0206965

    CAS:
    <p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>
    Fórmula:C21H21BrN4O5
    Pureza:99.13%
    Forma y color:Solid
    Peso molecular:489.32
  • physalin F

    CAS:
    <p>Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.Cost-effective and quality-assured.</p>
    Fórmula:C28H30O10
    Pureza:99.5% - 99.61%
    Forma y color:Solid
    Peso molecular:526.53
  • Aminopurvalanol A

    CAS:
    <p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>
    Fórmula:C19H26ClN7O
    Pureza:99.73%
    Forma y color:Solid
    Peso molecular:403.91
  • Apitolisib

    CAS:
    <p>Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).</p>
    Fórmula:C23H30N8O3S
    Pureza:98.28% - 99.64%
    Forma y color:Solid
    Peso molecular:498.6
  • PD173074

    CAS:
    <p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>
    Fórmula:C28H41N7O3
    Pureza:98.15% - 98.21%
    Forma y color:Yellow Solid
    Peso molecular:523.67
  • Dantrolene

    CAS:
    Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
    Fórmula:C14H10N4O5
    Pureza:99.97%
    Forma y color:Crystals From Aq Dimethylformamide
    Peso molecular:314.25
  • α-Mangostin

    CAS:
    alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.
    Fórmula:C24H26O6
    Pureza:98.22% - 99.49%
    Forma y color:Yellow Powder
    Peso molecular:410.46
  • DPN

    CAS:
    <p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>
    Fórmula:C15H13NO2
    Pureza:99.01%
    Forma y color:Off-White Solid
    Peso molecular:239.27
  • Selumetinib

    CAS:
    <p>Selumetinib (AZD6244) is a selectivity and non-ATP-competitive MEK1/2 inhibitor. Selumetinib has antitumor activity. Cost-effective and quality-assured.</p>
    Fórmula:C17H15BrClFN4O3
    Pureza:98.1% - 99.90%
    Forma y color:White Or Pale White Solid
    Peso molecular:457.68
  • SM-164

    CAS:
    <p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>
    Fórmula:C62H84N14O6
    Pureza:98.53% - 99.92%
    Forma y color:Solid
    Peso molecular:1121.42
  • Erdafitinib

    CAS:
    <p>Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.</p>
    Fórmula:C25H30N6O2
    Pureza:97.00% - 99.07%
    Forma y color:Solid
    Peso molecular:446.54
  • FTI-277 hydrochloride

    CAS:
    <p>FTI-277 HCl: potent FTase inhibitor, IC50 500 pM, 100x more selective than GGTase I.</p>
    Fórmula:C22H30ClN3O3S2
    Pureza:97.57% - 97.61%
    Forma y color:Solid
    Peso molecular:484.07
  • CID5721353

    CAS:
    <p>CID5721353 disrupts BCL6/corepressor complexes, binds critical BTB groove site in vitro/vivo.</p>
    Fórmula:C15H9BrN2O6S2
    Pureza:98.90%
    Forma y color:Solid
    Peso molecular:457.28
  • Nutlin-3a

    CAS:
    <p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>
    Fórmula:C30H30Cl2N4O4
    Pureza:95.62% - 99.71%
    Forma y color:Solid
    Peso molecular:581.49
  • Apoptozole

    CAS:
    <p>Apoptozole (Apoptosis Activator VII) is an inhibitor of the ATPase domain of Hsc70 and Hsp70, and can induce apoptosis.</p>
    Fórmula:C33H25F6N3O3
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:625.56
  • (-)-Epipodophyllotoxin

    CAS:
    (-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.
    Fórmula:C22H22O8
    Pureza:99.72% - 99.97%
    Forma y color:Solid
    Peso molecular:414.41
  • Quisinostat dihydrochloride

    CAS:
    <p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性,高效的 pan-HDAC 抑制剂,具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>
    Fórmula:C21H28Cl2N6O2
    Pureza:97.13%
    Forma y color:Solid
    Peso molecular:467.39
  • Atopaxar hydrochloride

    CAS:
    <p>Atopaxar hydrochloride is used in the Treatment of Cardiovascular Disorders.</p>
    Fórmula:C29H39ClFN3O5
    Forma y color:Solid
    Peso molecular:564.1
  • Resatorvid

    CAS:
    <p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>
    Fórmula:C15H17ClFNO4S
    Pureza:99.31% - >99.99%
    Forma y color:Solid
    Peso molecular:361.82
  • R1530

    CAS:
    <p>R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.</p>
    Fórmula:C18H14ClFN4O
    Pureza:98.422%
    Forma y color:Solid
    Peso molecular:356.78
  • Y-27632

    CAS:
    Y-27632 (Y-27632) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II.
    Fórmula:C14H21N3O
    Pureza:99.53% - 99.87%
    Forma y color:Solid
    Peso molecular:247.34
  • (6R)-FR054

    CAS:
    (6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.
    Fórmula:C14H19NO8
    Pureza:99.61%
    Forma y color:Solid
    Peso molecular:329.3
  • 3-Bromopyruvic acid

    CAS:
    <p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>
    Fórmula:C3H3BrO3
    Pureza:95% - 99.644%
    Forma y color:White To Pale Yellow Crystalline Powder
    Peso molecular:166.96
  • β-Elemonic Acid

    CAS:
    <p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>
    Fórmula:C30H46O3
    Pureza:99.61% - 99.8%
    Forma y color:Solid
    Peso molecular:454.68
  • Lexibulin

    CAS:
    <p>Lexibulin (CYT-997)(CYT-997) is a potent tubulin polymerization inhibitor (IC50: 10-100 nM, in Y cell lines).</p>
    Fórmula:C24H30N6O2
    Pureza:98.87%
    Forma y color:Solid
    Peso molecular:434.53
  • Cucurbitacin IIb

    CAS:
    <p>Cucurbitacin IIb is an active ingredient in Hemsleyadine, used to treat dysentery and other infections; it has anti-inflammatory effects.</p>
    Fórmula:C30H48O7
    Pureza:98.66% - >99.99%
    Forma y color:Solid
    Peso molecular:520.7
  • Poncirin

    CAS:
    <p>Poncirin inhibits human gastric cancer cell growth and prevents fat formation while boosting bone density and improving structure in osteoporosis mice.</p>
    Fórmula:C28H34O14
    Pureza:99.89% - 99.92%
    Forma y color:Solid
    Peso molecular:594.56