Apoptosis

<p>Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).</p>

<p>AZT triphosphate is a Nucleoside Triphosphate.</p>

<p>BCL6-IN-5 is a highly effective inhibitor of BCL6. It exhibits a pIC50 value of 5.82.</p>

<p>SB 202190 hydrochloride is a p38 MAPK inhibitor that inhibits p38α and p38β2 with selective, cell-permeable, and antitumor ,differentiation to cardiomyocytes.</p>

<p>Thalidomide D4 is a deuterium labeled Thalidomide, has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.</p>

<p>Bucladesine calcium: PDE inhibitor, boosts cAMP, activates PKA.</p>

<p>Rutin trihydrate is a natural flavonoid with antioxidant, anti-inflammatory, anti-diabetic, and anti-cancer benefits, plus heart and brain protection.</p>

<p>Capecitabine-d11 is a deuterated compound of Capecitabine. Capecitabine has a CAS number of 154361-50-9. Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.</p>

Isovalerylcarnitine (3-methylbutyrylcarnitine) is a selective effective calpain activator that can promote cell apoptosis and is related to isovaleric acidemia.

Gum Arabic, from A. Senegal, is an antioxidant that defends against hepatic, renal, and cardiac toxicities and aids in immunohistochemistry.

<p>TDE is an organochlorine insecticide with slightly irritating to the skin.</p>

Phenoxyethanol (Standard) is the standard substance of Phenoxyethanol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.

Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.

N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interaction with potential anticancer activity for cancer research.

CLZ-8 (Mcl1-IN-8) is a Mcl-1-PUMA inhibitor with radioprotective activity and inhibits radiation-induced overexpression of PUMA.

<p>PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits the growth of breast cancer cells.</p>

<p>Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor with anticancer activity.</p>