Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(8 productos)
- Caspasa(144 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(139 productos)
- PDK(9 productos)
- PERK(26 productos)
- Serina / treonina quinasa(18 productos)
- Survivin(14 productos)
- TNF(93 productos)
- c-RET(61 productos)
- p53(63 productos)
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Se han encontrado 6084 productos de "Apoptosis"
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C199
C199 is a PROTAC degrader targeting PRMT4 with a DC50 of 106 nM. It demonstrates high selectivity for PRMT4 compared to other protein arginine methyltransferases. C199 exhibits strong cellular degradation capacity and induces apoptosis in multiple myeloma cell lines. It efficiently eliminates PRMT4 protein through the VHL-proteasome pathway. C199 has a relatively long half-life and shows potent anti-multiple myeloma (MM) activity.Forma y color:Odour SolidPL120131
PL120131 is a PD-1/PD-L1 inhibitory peptide that disrupts the interaction between PD-1 and PD-L1 by binding to PD-1. This compound can inhibit the apoptosis signaling pathway mediated by PD-1, thereby preventing apoptosis (apoptosis) in Jurkat cells and primary lymphocytes. Additionally, PL120131 supports cytotoxic T lymphocytes (CTL) in exhibiting antitumor activity.Fórmula:C62H105N19O18Forma y color:SolidPeso molecular:1404.61RIPK3-IN-3
RIPK3-IN-3 (compound 20) is a selective RIPK3 inhibitor that demonstrates potent activity with an IC50 value of 10 nM.Fórmula:C16H11N5SForma y color:SolidPeso molecular:305.36Pentagamavunon-1
CAS:PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.Fórmula:C23H24O3Forma y color:SolidPeso molecular:348.4313-Methyltetradecanoic acid
CAS:LeDSF3 controls HSAF production in Lysobacter, has antifungal properties, and acts as an anti-tumor by inhibiting p-AKT and activating caspase-3.Fórmula:C15H30O2Forma y color:SolidPeso molecular:242.4NU 9056
CAS:NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM.Fórmula:C6H4N2S4Pureza:95.36% - 97.11%Forma y color:SolidPeso molecular:232.37CuATSM
CAS:Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.Fórmula:C8H14CuN6S2Forma y color:SolidPeso molecular:321.92Cobimetinib hemifumarate
CAS:Cobimetinib hemifumarate is a potent and selective MEK1 inhibitor with an IC50 value of 4.2 nM for MEK1.Fórmula:C46H46F6I2N6O8Forma y color:SolidPeso molecular:1178.707Rottlerin
CAS:Fórmula:C30H28O8Pureza:>95.0%(HPLC)(qNMR)Forma y color:Light yellow to Brown powder to crystalPeso molecular:516.55Isovalerylcarnitine
CAS:Isovalerylcarnitine (3-methylbutyrylcarnitine) is a selective effective calpain activator that can promote cell apoptosis and is related to isovaleric acidemia.Fórmula:C12H23NO4Pureza:98.24%Forma y color:SolidPeso molecular:245.32Melflufen hydrochloride
CAS:Melflufen HCl: prodrug of Melphalan, has antitumor and antiangiogenic effects, causes DNA damage in MM cells.Fórmula:C24H31Cl3FN3O3Forma y color:SolidPeso molecular:534.88Mepazine hydrochloride
CAS:Mepazine hydrochloride (Pecazine hydrochloride) is a MALT1 inhibitor with anticancer and antitumor activity, inhibiting RANK-induced osteoclastogenesis.Fórmula:C19H23ClN2SPureza:99.76%Forma y color:SolidPeso molecular:346.92PR-924
CAS:PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM).Fórmula:C37H38N4O5Pureza:98%Forma y color:SolidPeso molecular:618.72Fenvalerate
CAS:Fenvalerate (Evercide 2362) is a protein phosphatase 2B (calcineurin) inhibitor, a synthetic pyrethroid insecticide, that inhibits PP2B-Aα.Fórmula:C25H22ClNO3Pureza:99.62%Peso molecular:419.90Fenobucarb
CAS:Fenobucarb is a broad-spectrum carbamate insecticide and AChE inhibitor. It exhibits neurotoxicity to zebrafish foetal development and induces muscle spasmsFórmula:C12H17NO2Pureza:98.80%Forma y color:White CrystalPeso molecular:207.27Ulipristal Acetate
CAS:Fórmula:C30H37NO4Pureza:>98.0%(T)(HPLC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:475.63Ancitabine
CAS:Ancitabine is an antitumour drug that improves Hailey-Hailey disease-related phenotypes in yeast models. inhibits DNA synthesis, acute leukaemia.Fórmula:C9H11N3O4Pureza:99.91%Forma y color:SolidPeso molecular:225.2Pitavastatin D4
CAS:Pitavastatin D4 is deuterium labeled Pitavastatin. Pitavastatin is a potent inhibitor of HMG-CoA reductase.Fórmula:C25H24FNO4Pureza:98%Forma y color:SolidPeso molecular:425.49PND-1186 hydrochloride
CAS:PND-1186 hydrochloride (VS-4718 hydrochloride) is a highly specific, reversible and potent inhibitor of FAK (IC50: 1.5 nM), which can selectively induceFórmula:C25H27ClF3N5O3Forma y color:SolidPeso molecular:537.97Sunitinib-d10
CAS:Sunitinib D10, a deuterium-enriched version, inhibits VEGFR2 and PDGFRβ tyrosine kinases (IC50: 80 nM/2 nM).Fórmula:C22H27FN4O2Pureza:98%Forma y color:SolidPeso molecular:408.54
