Apoptosis

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat FASL. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat FASL. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat FASL, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat FASL in the samples is then determined by comparing the OD of the samples to the standard curve.

<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>

Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.

Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset

<p>Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.</p>

<p>Prucalopride (R-93877), a selective 5-HT4A/4B agonist (Ki: 2.5/8 nM), is &gt;290x more specific for these receptors.</p>

Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.

<p>Ac-YVAD-CMK: Irreversible Caspase-1 inhibitor; halts pyroptosis, IL-1β/IL-18; neuroprotective and anti-inflammatory.</p>

<p>Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.</p>

Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.

Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.

Tislelizumab, a PD-1 receptor monoclonal antibody, reduces Fcγ interaction and T cell clearance in advanced squamous NSCLC research.

<p>PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells</p>

<p>Budigalimab (ABBV 181) is a humanized monoclonal antibody targeting PD-1 with potential antitumor activity.</p>

<p>Carbaryl is a carbamate insecticide/parasiticide with low dermal toxicity used against head lice.</p>

<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>

Geniposidic acid, an iridoid glucoside, used in therapy of jaundice, inflammation and hepatic disorders.

<p>Cinchonine (LA40221), a potent amide local anesthetic for surface use, is toxic and limited to spinal anesthesia.</p>

<p>N-Oleoyl-L-Serine (N-Oleoylserine) is a lipid modulator of bone remodeling and stimulates osteoclast apoptosis for the study of osteoporosis.</p>

Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotide