Apoptosis
Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.
Subcategorías de "Apoptosis"
- ASK(9 productos)
- BCL(11 productos)
- Caspasa(142 productos)
- FOXO1(3 productos)
- IAP(67 productos)
- Mdm2(12 productos)
- PD-1 / PD-L1(138 productos)
- PDK(9 productos)
- PERK(25 productos)
- Serina / treonina quinasa(14 productos)
- Survivin(14 productos)
- TNF(89 productos)
- c-RET(56 productos)
- p53(63 productos)
Mostrar 6 subcategorías más
Se han encontrado 5903 productos de "Apoptosis"
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MI-888 free base
CAS:MI-888 is the most potent MDM2 inhibitor (Ki = 0.44 nM), with high oral efficacy in human cancer models and optimal pharmacokinetics.Fórmula:C28H32Cl2FN3O3Forma y color:SolidPeso molecular:548.48TMX-2164
CAS:TMX-2164: strong, irreversible BCL6 inhibitor, IC50=152 nM, long-lasting action, inhibits cell proliferation.Fórmula:C25H24ClFN6O6SForma y color:SolidPeso molecular:591.01GDC-2394
CAS:GDC-2394: Oral, selective NLRP3 inhibitor; blocks IL-1β (human 0.4μM, mouse 0.1μM), spares NLRC4.Fórmula:C20H25N5O4SForma y color:SolidPeso molecular:431.51Met-F-AEA
CAS:<p>Met-F-AEA is a metabolically stable analogue of anandamine that exhibits antitumor activity by inhibiting cell growth through the activation of apoptosis [1].</p>Fórmula:C23H38FNOForma y color:SolidPeso molecular:363.561CNDAC
CAS:CNDAC, a nucleoside analog, is a major metabolite of oral drug sapacitabine.Fórmula:C10H12N4O4Pureza:98%Forma y color:SolidPeso molecular:252.23RET-IN-13
CAS:RET-IN-13: potent quinoline RET inhibitor; IC50 = 0.5 nM (WT), 0.9 nM (V804M); potential for RET-related tumor/intestinal disease research.Fórmula:C32H33F4N5O3Forma y color:SolidPeso molecular:611.63Agerafenib hydrochloride
CAS:Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).Fórmula:C24H23ClF3N5O5Pureza:98%Forma y color:SolidPeso molecular:553.92YM281
CAS:<p>YM281 is a potent EZH2 inhibitor, causes apoptosis and G0/G1 arrest, has antitumor activity in vivo, and may be researched for lymphoma.</p>Fórmula:C56H71N7O9SForma y color:SolidPeso molecular:1018.27INCB3619
CAS:INCB3619 is a selective and potent inhibitor of ADAM with antitumour effects, inhibiting ADAM10, ADAM17, MMP12 and MMP15.Fórmula:C22H27N3O5Pureza:98.41% - 99.51%Forma y color:SolidPeso molecular:413.47Famitinib malate
CAS:Famitinib malate (SHR1020) is a potent oral kinase inhibitor targeting c-kit, VEGFR-2, and PDGFRβ, with IC50s 2.3, 4.7, 6.6 nM, useful for cancer research.Fórmula:C27H33FN4O7Forma y color:SolidPeso molecular:544.57SM-433
CAS:<p>SM-433: Smac mimetic, blocks IAPs, strong XIAP BIR3 affinity (IC50 <1 μM). See patent WO2008128171A2.</p>Fórmula:C32H43N5O4Forma y color:SolidPeso molecular:561.71Estrogen receptor modulator 10
CAS:<p>Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM).</p>Fórmula:C32H37F9N4O3SPureza:98%Forma y color:SolidPeso molecular:728.71Ezatiostat hydrochloride
CAS:Ezatiostat HCl (TLK199) inhibits glutathione S-transferase, GSTP1-1 specifically, and may treat cytopenias.Fórmula:C27H36ClN3O6SPureza:98%Forma y color:SolidPeso molecular:566.11Ac-VAD-CHO
CAS:<p>Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release of</p>Fórmula:C14H23N3O6Pureza:98%Forma y color:SolidPeso molecular:329.35IM156
CAS:IM156, a Metformin derivative, activates AMPK, enhances cognition in aging animals, and inhibits OXPHOS in solid tumor research.Fórmula:C13H16F3N5OPureza:99.67%Forma y color:SolidPeso molecular:315.29ERα antagonist 1
CAS:<p>ERα antagonist 1 is a selective, potent, covalent estrogen receptor alpha (ERα) antagonist that blocks the cell cycle of MCF-7 cells in G0/G1 phase and induces</p>Fórmula:C33H32N2O5SForma y color:SolidPeso molecular:568.68CUR61414
CAS:<p>CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) and selectively binds to smoothened (Ki = 44 nM).</p>Fórmula:C31H42N4O5Pureza:97.34% - 98%Forma y color:SolidPeso molecular:550.69IK-862
CAS:<p>IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.</p>Fórmula:C25H27N3O4Pureza:97.75% - 98.29%Forma y color:SolidPeso molecular:433.5SW IV-52
CAS:SW IV-52 is an XIAP-inhibitor that acts as a second mitochondria-derived activator of caspases (SMAC) mimetic.Fórmula:C25H39ClN4O3Pureza:98%Forma y color:SolidPeso molecular:479.05viFSP1
CAS:<p>viFSP1, a species-independent FSP1 inhibitor, effectively induces ferroptosis in FSP1-dependent cells by targeting the highly conserved NAD(P)H binding pocket of FSP1, directly inhibiting its activity. This action results in lipid peroxidation and exhibits anticancer activity [1].</p>Fórmula:C16H17N3O3SForma y color:SolidPeso molecular:331.39
