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Apoptosis

Apoptosis

Los inhibidores de la apoptosis son compuestos que previenen o retrasan el proceso de muerte celular programada, conocido como apoptosis. Estos inhibidores son vitales para estudiar los mecanismos de supervivencia celular y se utilizan para investigar enfermedades donde la apoptosis está desregulada, como el cáncer, los trastornos neurodegenerativos y las enfermedades autoinmunes. Al modular la apoptosis, estos inhibidores pueden ayudar en el desarrollo de terapias dirigidas a controlar la muerte celular. En CymitQuimica, ofrecemos una amplia selección de inhibidores de la apoptosis de alta calidad para apoyar su investigación en biología celular, oncología y campos relacionados.

Subcategorías de "Apoptosis"

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Se han encontrado 5903 productos de "Apoptosis"

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  • APE1-IN-2
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    APE1-IN-2

    CAS:
    <p>APE1-IN-2 (AP1), a Pt(IV) proagent, targets APE1 protein, induces DNA damage, and triggers apoptosis with anticancer effects.</p>
    Fórmula:C9H12Cl2N4O5Pt
    Pureza:98%
    Forma y color:Solid
    Peso molecular:522.21

    Ref: TM-T73299

  • Atiprimod dihydrochloride
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    Atiprimod dihydrochloride

    CAS:
    JAK2 inhibitor; IC50=397 nM; hampers STAT3/5 phosphorylation; curbs growth and triggers apoptosis in JAK2V617F+ cells.
    Fórmula:C22H46Cl2N2
    Forma y color:Solid
    Peso molecular:409.52

    Ref: TM-T35894

  • PARP-1-IN-3
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    PARP-1-IN-3

    CAS:
    <p>PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-</p>
    Fórmula:C21H17BrN2O3
    Pureza:98.38%
    Forma y color:Solid
    Peso molecular:425.28

    Ref: TM-T78157

  • Mezigdomide
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    Mezigdomide

    CAS:
    <p>Mezigdomide (CC-92480) is a potent, novel cereblon E3 ubiquitin ligase modulator (CELMoD) that acts as a molecular glue.Cost-effective and quality-assured.</p>
    Fórmula:C32H30FN5O4
    Pureza:97.21% - 99.68%
    Forma y color:Solid
    Peso molecular:567.61

    Ref: TM-T10703

  • Riboxin
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    Riboxin

    CAS:
    Riboxin (IDP), an orally administered purine derivative known as hypoxanthine riboside, exhibits antihypoxic and antihyperthermic effects.
    Fórmula:C10H14N4O11P2
    Forma y color:Solid
    Peso molecular:428.19

    Ref: TM-T81275

  • 2-O-methyl PAF C-16
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    2-O-methyl PAF C-16

    CAS:
    2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS).
    Fórmula:C25H54NO6P
    Forma y color:Solid
    Peso molecular:495.7

    Ref: TM-T84610

  • Ac-VAD-CHO
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    Ac-VAD-CHO

    CAS:
    <p>Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release of</p>
    Fórmula:C14H23N3O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:329.35

    Ref: TM-T80624

  • Bcl-2-IN-16
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    Bcl-2-IN-16

    CAS:
    Bcl-2-IN-16 is a Bcl-2 (B-cell lymphoma 2) inhibitor [1].
    Fórmula:C53H63ClN8O10S
    Forma y color:Solid
    Peso molecular:1039.63

    Ref: TM-T82910

  • c-Met/MEK1/Flt-3-IN-1
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    c-Met/MEK1/Flt-3-IN-1

    Antiproliferative Against-3 (comp 33) demonstrates significant activity against Hela (IC 50 = 0.21 µM), A549 (IC 50 = 0.39 µM), and MCF-7 (IC 50 = 0.33 µM) cell
    Fórmula:C39H37FN6O5
    Forma y color:Solid
    Peso molecular:688.75

    Ref: TM-T72407

  • AGN 192870
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    AGN 192870

    CAS:
    AGN 192870 is a potent retinoic acid receptor (RAR) antagonist.AGN 192870 can be used to study cell growth arrest, differentiation and apoptosis.
    Fórmula:C27H22O2
    Pureza:99.22%
    Forma y color:Solid
    Peso molecular:378.46

    Ref: TM-T61588

  • MC2590
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    MC2590

    CAS:
    MC2590 is a histone deacetylase (HDAC) inhibitor that inhibits HDAC1-3, -6, -8, and -10 activities, induces cell cycle arrest, and promotes apoptosis.
    Fórmula:C20H17N3O3
    Pureza:99.64%
    Forma y color:Solid
    Peso molecular:347.37

    Ref: TM-T73515

  • DLC-50
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    DLC-50

    CAS:
    <p>DLC-50 is a dual inhibitor of PARP-1 and HDAC-1, exhibiting IC50 values of 1.2 nM and 31 nM respectively. It hinders the proliferation of cancer cells such as MDA-MB-436, MDA-MB-231, and MCF-7 with IC50 values of 0.3 μM, 2.7 μM, and 2.41 μM respectively. Additionally, DLC-50 induces apoptosis in MDA-MB-231 cells and causes cell cycle arrest at the G2 phase.</p>
    Fórmula:C28H32FN5O4S2
    Forma y color:Solid
    Peso molecular:585.71

    Ref: TM-T88516

  • erythro-Austrobailignan-6
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    erythro-Austrobailignan-6

    CAS:
    Erythro-Austrobailignan-6: orally active, anti-cancer, inhibits DNA topoisomerases, induces apoptosis, boosts p38/JNK phosphorylation.
    Fórmula:C20H24O4
    Forma y color:Solid
    Peso molecular:328.4

    Ref: TM-T72236

  • BMS-561392 formate
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    BMS-561392 formate

    CAS:
    BMS-561392 formate, the formate derivative of BMS-561392, functions as a TNF alpha-converting enzyme (TACE) inhibitor and an ADAM17 blocker. It is utilized in the research of inflammatory bowel disease [1] [2].
    Fórmula:C28H34N4O6
    Forma y color:Solid
    Peso molecular:522.59

    Ref: TM-T84690

  • GGTI2417
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    GGTI2417

    CAS:
    <p>GGTI2417 blocks Geranylgeranyltransferase I, targeting RalB for apoptosis and RalA to stop growth.</p>
    Fórmula:C24H33N5O4
    Forma y color:Solid
    Peso molecular:455.55

    Ref: TM-T27412

  • Necrostatin-1 (inactive control)
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    Necrostatin-1 (inactive control)

    CAS:
    Necrostatin-1 (Nec-1) (inactive control), an inactive analog of Necrostatin-1, functions as a potent inhibitor of necroptosis [1].
    Fórmula:C12H11N3OS
    Forma y color:Solid
    Peso molecular:245.3

    Ref: TM-T84727

  • CDDO-3P-Im
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    CDDO-3P-Im

    CAS:
    <p>CDDO-3P-Im is an orally active inhibitor of necroptosis with chemopreventive effects. CDDO-3P-Im can be used in studies about ischemia/reperfusion.</p>
    Fórmula:C39H46N4O3
    Pureza:97.72%
    Forma y color:Solid
    Peso molecular:618.81

    Ref: TM-T13603

  • Nanatinostat
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    Nanatinostat

    CAS:
    Nanatinostat (CHR-3996) is an HDAC inhibitor with selectivity and oral bioavailability, for HDAC1/2/3 .anti-proliferation apoptosis.
    Fórmula:C20H19FN6O2
    Pureza:99.03%
    Forma y color:Solid
    Peso molecular:394.4

    Ref: TM-T16270

  • AZA197
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    AZA197

    CAS:
    AZA197 (AZA-197) is a selective Cdc42 inhibitor.
    Fórmula:C24H36N6
    Pureza:99.08%
    Forma y color:Solid
    Peso molecular:408.58

    Ref: TM-T25125

  • GCN2-IN-7
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    GCN2-IN-7

    CAS:
    GCN2-IN-7 is an inhibitor of the environmental sensing protein GCN2 with antitumor activity for the study of melanoma.
    Fórmula:C22H23BrN8OS
    Pureza:99.12%
    Forma y color:Solid
    Peso molecular:527.44

    Ref: TM-T63699